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    BIOABSORBABLE BIOMEDICAL IMPLANTS
    14.
    发明专利
    BIOABSORBABLE BIOMEDICAL IMPLANTS 未知

    公开(公告)号：CA2912387C

    公开(公告)日：2019-04-16

    申请号：CA2912387

    申请日：2014-05-15

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： MCCLAIN JAMES B

    IPC: A61L27/58 ,  A61F2/00 ,  A61F2/07 ,  A61F2/82 ,  A61L27/44 ,  A61L27/54 ,  A61L27/56 ,  A61L31/12

    Abstract: A bioabsorbable biomedical implant is disclosed. The implant includes a tubular scaffold comprising a plurality of interconnected polymer struts. The interconnected polymer struts defines a plurality of deformable cells. The polymer struts have an average thickness of no more than 150 µm. Methods for making the bioabsorbable biomedical implant, including the methods for making the fiber-reinforced polymer composite materials for the tubular scaffold, are also disclosed.

    PROLONGED DRUG-ELUTING PRODUCTS
    16.
    发明专利
    PROLONGED DRUG-ELUTING PRODUCTS 未知

    公开(公告)号：CA2977289A1

    公开(公告)日：2018-03-23

    申请号：CA2977289

    申请日：2017-08-22

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： KIORPES TIMOTHY CHARLES ,  MCCLAIN JAMES B

    IPC: A61L31/16 ,  A61K9/00 ,  A61K47/34 ,  A61L27/50 ,  A61L27/54 ,  A61L31/14

    Abstract: A drug-eluting product is disclosed comprising an at least partially bioabsorbable element and an active pharmaceutical agent having a morphology, a solubility, and an average particle size which are selected so that the active pharmaceutical agent continues to dissolve during the biodegradation of the bioabsorbable element. The morphology is a crystalline, semi-crystalline or amorphous morphology, the solubility is less than 100 µg/ml and the average particle size is grater that about 100 nm.

    DRUG/POLYMER COMPOSITE MATERIALS AND METHODS OF MAKING THE SAME
    17.
    发明专利
    DRUG/POLYMER COMPOSITE MATERIALS AND METHODS OF MAKING THE SAME 未知

    公开(公告)号：CA2922492C

    公开(公告)日：2018-02-20

    申请号：CA2922492

    申请日：2006-06-21

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： MCCLAIN JAMES B ,  DEYOUNG JAMES P

    IPC: A61K9/00

    Abstract: A method of forming a drug/polymer composite material is carried out by combining a drug material with a polymer material under pressure in the presence of a densified gas solvent (e.g., carbon dioxide) to form the drug/polymer composite material. Drug/polymer composite materials and shaped articles (e.g., subcutaneous drug depots) which may be produced by a process are also described, along with methods of use thereof.

    DRUG DELIVERY MEDICAL DEVICE
    18.
    发明专利
    DRUG DELIVERY MEDICAL DEVICE 未知

    公开(公告)号：CA2730995C

    公开(公告)日：2016-11-22

    申请号：CA2730995

    申请日：2009-07-16

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： MCCLAIN JAMES B ,  TAYLOR DOUGLAS ,  NEET JOHN

    IPC: A61L29/08 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16

    Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.

    STENTS HAVING BIODEGRADABLE LAYERS
    20.
    发明专利
    STENTS HAVING BIODEGRADABLE LAYERS 未知

    公开(公告)号：HK1208634A1

    公开(公告)日：2016-03-11

    申请号：HK15109302

    申请日：2015-09-23

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： MCCLAIN JAMES B ,  TAYLOR DOUGLAS

    IPC: A61L20060101 ,  A61F2/82

    Abstract: Provided herein is a coated coronary stent, comprising: a. stent framework; b. a plurality of layers deposited on said stent framework to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.

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