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公开(公告)号:CA2730995C
公开(公告)日:2016-11-22
申请号:CA2730995
申请日:2009-07-16
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS , NEET JOHN
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.
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公开(公告)号:CA2841360A1
公开(公告)日:2013-01-24
申请号:CA2841360
申请日:2012-07-12
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , ZANI BRETT G , NEET JOHN , KIORPES TIMOTHY CHARLES
IPC: A61F2/06
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on the substrate, wherein the coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within the coating and on the substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of the medical device in the body of the subject a portion of the pharmaceutical agent and/or active biological agent is delivered at the intervention site along with at least a portion of the polymer and/or a at least a portion of the pharmaceutical carrying agents.
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公开(公告)号:CA2805631C
公开(公告)日:2018-07-31
申请号:CA2805631
申请日:2011-07-15
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , ZANI BRETT G , NEET JOHN , KIORPES TIMOTHY CHARLES
IPC: A61L29/08 , A61K9/00 , A61K31/436 , A61L29/16 , A61M31/00
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on the substrate, wherein the coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within the coating and on the substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of the medical device in the body of the subject a portion of the pharmaceutical agent and/or active biological agent is delivered at the intervention site along with at least a portion of the polymer and/or a at least a portion of the pharmaceutical carrying agents.
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公开(公告)号:CA2805631A1
公开(公告)日:2012-01-19
申请号:CA2805631
申请日:2011-07-15
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , ZANI BRETT G , NEET JOHN , KIORPES TIMOTHY CHARLES
IPC: A61L29/08 , A61K9/00 , A61K31/436 , A61L29/16 , A61M31/00
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on the substrate, wherein the coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within the coating and on the substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of the medical device in the body of the subject a portion of the pharmaceutical agent and/or active biological agent is delivered at the intervention site along with at least a portion of the polymer and/or a at least a portion of the pharmaceutical carrying agents.
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公开(公告)号:CA2946195A1
公开(公告)日:2010-01-21
申请号:CA2946195
申请日:2009-07-16
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS , NEET JOHN
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.
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公开(公告)号:CA2730995A1
公开(公告)日:2010-01-21
申请号:CA2730995
申请日:2009-07-16
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS , NEET JOHN
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.
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公开(公告)号:AU2009270849A1
公开(公告)日:2010-01-21
申请号:AU2009270849
申请日:2009-07-16
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS , NEET JOHN
IPC: A61L33/00
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.
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公开(公告)号:WO2010111232A2
公开(公告)日:2010-09-30
申请号:PCT/US2010028253
申请日:2010-03-23
Applicant: MICELL TECHNOLOGIES INC , NEET JOHN , TAYLOR DOUGLAS , MCCLAIN JAMES B
Inventor: NEET JOHN , TAYLOR DOUGLAS , MCCLAIN JAMES B
CPC classification number: A61L31/16 , A61L27/16 , A61L27/34 , A61L29/085 , A61L29/16 , A61L31/10 , A61L2300/602 , A61L2300/608 , A61L2300/63 , A61L2420/08 , A61M25/0045
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.
Abstract translation: 提供一种涂覆的可植入医疗装置,包括:基底; 以及设置在所述基底上的涂层,其中所述涂层包含至少一种聚合物和至少一种治疗上需要的形态和/或至少一种活性生物试剂和任选的一种或多种药物载体的药剂; 其中基本上所有的药剂和/或活性生物制剂都保留在所述涂层内和所述衬底上,直到所述可植入装置部署在受试者身体内部的介入部位,并且其中在将所述医疗装置部署在所述受试者的身体中时 所述药剂和/或活性生物剂的一部分与所述聚合物的至少一部分和/或所述药物载体的至少一部分在所述介入部位递送。
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公开(公告)号:CA2756386C
公开(公告)日:2019-01-15
申请号:CA2756386
申请日:2010-03-23
Applicant: MICELL TECHNOLOGIES INC
Inventor: NEET JOHN , TAYLOR DOUGLAS , MCCLAIN JAMES B
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.
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公开(公告)号:AU2009270849B2
公开(公告)日:2013-11-21
申请号:AU2009270849
申请日:2009-07-16
Applicant: MICELL TECHNOLOGIES INC
Inventor: TAYLOR DOUGLAS , MCCLAIN JAMES B , NEET JOHN
IPC: A61L33/00
Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.
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