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公开(公告)号：KR1020120119189A
公开(公告)日：2012-10-30
申请号：KR1020110036997
申请日：2011-04-20
Applicant: 대구가톨릭대학교산학협력단 , 서미자
IPC: C07D311/30 , C07C65/10 , A61K36/605 , A61P39/06
Abstract: PURPOSE: A manufacturing method of mulberry seed originated polyphenol compound is provided to enhance antioxidant function, thereby being useful for cosmestic material. CONSTITUTION: A polyphenol compound is one of compounds having chemical structure 1-11 which are originated from mulberry seed. An isolation refining method of the polyphenol compound comprises the following steps: obtaining mulberry seed oil and defatted meal by compressing the mulberry seed; organic solvent extracting degatted meal; and silica-gel, sephadex LH-20, ODS-A column chromatographing ethyl acetate fraction. The functional food for antioxidant contains mulberry seed originated polyphenol compound.
Abstract translation: 目的：提供桑树种子起源的多酚化合物的制造方法，以增强抗氧化功能，从而可用于美容材料。 构成：多酚化合物是起源于桑树种子的具有化学结构1-11的化合物之一。 多酚化合物的分离精制方法包括以下步骤：通过压缩桑树种子获得桑树籽油和脱脂粉; 有机溶剂提取脱盐粉; 和硅胶，sephadex LH-20，ODS-A柱层析乙酸乙酯级分。 抗氧化功能性食品含有桑树种子起源于多酚化合物。
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公开(公告)号：KR101371194B1
公开(公告)日：2014-03-12
申请号：KR1020120025594
申请日：2012-03-13
Applicant: 대구가톨릭대학교산학협력단 , (주)에스.앤.디
IPC: A61K31/404 , A61K36/815 , A61P3/00
Abstract: 본 발명은 구기자 뿌리껍질인 지골피(
Lycii Cortex Radicis , LCR)로부터 유래한 티라민 유도체(CT, FT)의 항콜레스테롤 효능에 관한 것으로, 지골피 유래의 티라민 유도체는 HMG-CoA 환원효소와 ACAT의 활성을 저해하고, 동물실험을 통하여 혈청 총콜레스테롤 감소효과 뿐만 아니라, 특히 LCR 페놀릭아마이드 FT는 잇꽃종자유래의 FS(
N- feruloylserotonin) 수준의 상기 효소저해 효과가 있고 페놀릭아마이드를 포함하는 LCR 추출물은 저농도에서도 잇꽃종자추출물 유래의 serotonin보다 혈청 콜레스테롤 수준을 감소시키는 뛰어난 효과가 있다-
公开(公告)号：KR1020120119809A
公开(公告)日：2012-10-31
申请号：KR1020110038010
申请日：2011-04-22
Applicant: 대구가톨릭대학교산학협력단
Abstract: PURPOSE: Mulberry jam and a producing method thereof are provided to use high-quality mulberry syrup obtained from assorted mulberry to produce the jam. CONSTITUTION: A producing method of mulberry jam comprises the following steps: assorting and washing mulberry; mixing the washed mulberry and sugar in a weight ratio of 1:1; sealing, fermenting, and aging the mixture for 3-9 months, and filtering the mixture using a 20mesh sieve to obtain mulberry syrup; mixing the mulberry syrup with mulberry syrup flesh, and heating the mixture at 70 deg. C for 10 minutes before stirring; removing stems from the stirred mixture, and refining the mulberry syrup flesh; adding pectin to the refined mulberry syrup flesh; and coagulating the mixture before stopping the heating process and adding citric acid and vitamin C and sterilizing the mixture. [Reference numerals] (AA) Fresh mulberry; (BB) Dressing; (CC) Sugar-preserving; (DD) Sealed-aging; (EE) Filtering; (FF) Original mulberry jam flesh; (GG) Crushing; (HH) Stirring(removing stems); (II) Refining(mulberry jam flesh); (JJ) (fresh mulberry:sugar=1:1); (KK) (3-9 months); (LL) (sieve); (MM) Mulberry extract
Abstract translation: 目的：提供桑果果酱及其生产方法，以使用从各种桑树获得的优质桑果糖浆产生果酱。 构成：桑果果酱的生产方法包括以下步骤：桑树分类和洗涤; 以1：1的重量比混合洗涤的桑树和糖; 密封，发酵和熟化混合物3-9个月，并用20目筛过滤混合物，得到桑树浆; 将桑树浆与桑叶糖浆混合，并在70度加热混合物。 搅拌10分钟; 从搅拌的混合物中除去茎，并精制桑叶糖浆; 将果胶加入到精制桑叶浆中; 并在停止加热过程之前凝结混合物，并加入柠檬酸和维生素C并对混合物进行灭菌。 （附图标记）（AA）新鲜桑树; （BB）敷料; （CC）保糖; （DD）密封老化; （EE）过滤; （FF）原桑果果酱肉; （GG）粉碎; （HH）搅拌（去除茎）; （二）精炼（桑果果肉）; （JJ）（新鲜桑berry：糖= 1：1）; （KK）（3-9个月）; （LL）（筛）; （MM）桑树提取物
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公开(公告)号：KR1020110121487A
公开(公告)日：2011-11-07
申请号：KR1020100041094
申请日：2010-04-30
Applicant: 대구가톨릭대학교산학협력단 , 서미자
IPC: A61K36/14 , A61K36/264 , A61K8/97 , A61Q19/08
CPC classification number: A61K36/14
Abstract: PURPOSE: An oriental medicine material extract containing eugenol derivatives and a method for preparing the same are provided to ensure antioxidation, anti-aging, and anti-inflammation. CONSTITUTION: A method for preparing steam distillation extract of oriental medicine materials comprises: a step of drying herb medicines and adding distilled water; a step of adding ether and isolating with a steam distillation device; and a step of decompressing. A functional composition for antioxidation or antiaging contains the extract as an active ingredient. A functional composition for anti-inflammation contains the extract as an active ingredient. The extract contains eugenol derivatives as an active ingredient. The eugenol derivative is methyleugenol or acetyleugenol.
Abstract translation: 目的：提供含有丁子香酚衍生物的东方药物提取物及其制备方法，以确保抗氧化，抗衰老和抗炎。 构成：东方药材蒸汽蒸馏提取物的制备方法，包括：草药干燥，加入蒸馏水的步骤; 加入乙醚并用蒸汽蒸馏装置分离的步骤; 和解压缩的一个步骤。 用于抗氧化或抗衰老的功能组合物含有提取物作为活性成分。 用于抗炎的功能组合物含有提取物作为活性成分。 提取物含有丁子香酚衍生物作为活性成分。 丁子香酚衍生物是甲基丁烯醇或乙酰丁烯醇。
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公开(公告)号：KR1020090067273A
公开(公告)日：2009-06-25
申请号：KR1020070134845
申请日：2007-12-21
Applicant: 대구가톨릭대학교산학협력단
Abstract: An enzyme-treated seasoning and a preparation method thereof are provided to improve solubility, digestibility and preference while maintaining the functionality and nutrients of natural ingredients through extrusion molding and enzymatic treatment. A method for preparing an enzyme-treated seasoning comprises the following steps of: performing a first extraction molding; fermenting the first-extrusion molded material with an enzyme solution; performing a second extrusion molding; drying the second-extrusion molded material in a hot air drier until the moisture content becomes 5% or less; pulverizing the dried material 200-250 mesh in size; and collecting the pulverized material by a cyclone. The seasoning composition consists of 55wt% of freeze-dried shrimp, 5wt% of anchovy, 5wt% of sea tangle, 5wt% of pyogo mushroom, 5wt% of garlic, 2wt% of bean sprouts, 2wt% of radish, 2wt% of onion, 2wt% of ginger, 1wt% of Alaska Pollack, 1wt% of bonito, 1wt% of sea mussel, 1wt% of cuttlefish, 1wt% of sesame, 1wt% of Korean leek, 1wt% of red pepper and 10wt% of salicornia herbacea.
Abstract translation: 提供酶处理的调味料及其制备方法以通过挤出成型和酶处理来保持天然成分的功能和营养，从而提高溶解性，消化率和偏好。 制备酶处理调味料的方法包括以下步骤：进行第一次提取成型; 用酶溶液发酵第一挤出成型材料; 进行第二挤压成型; 在热空气干燥器中干燥第二挤出成型材料直到水分含量变为5％以下; 粉碎尺寸为200-250目的干燥材料; 并通过旋风收集粉碎物料。 调味成分由冻干虾55％，an鱼5％，海螯虾5％，py菇5％，大蒜5％，豆芽2％，萝卜2％，洋葱2％ ，2重量％的姜，1重量％的bon鱼，1重量％的bon鱼，1重量％的贻贝，1重量％的墨鱼，1重量％的芝麻，1重量％的韩国韭菜，1重量％的红辣椒和10重量％的水ia草 。
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Patent Agency Ranking
公开(公告)号：KR1020160101782A
公开(公告)日：2016-08-26
申请号：KR1020150024185
申请日：2015-02-17
Applicant: 대구가톨릭대학교산학협력단
IPC: A23G3/48
CPC classification number: A23G3/48
Abstract: 본발명은오디분말및 뽕잎분말에한천, 설탕과팥앙금를이용하여제조하는기존의오디및 뽕잎양갱과달리발효하거나찜처리및 볶음처리하여기능성및 기호성을배가시킨오디및 뽕잎가공품을이용한고품질의기능성오디및 뽕잎양갱제조방법에관한것으로더욱상세하게는, 뽕나무열매오디를흑설탕과올리고당으로저온숙성하여만든발효오디청과오디청을알코올및 초산발효하여만든오디식초, 그리고발효오디식초를만들때부산물로나오는오디씨를고명으로하여만든기능성오디양갱과뽕잎을쪄서열풍건조하여분말화한뽕잎분말과상지(뽕나무가지)를볶아서물로추출한상지추출물로만든기능성뽕잎양갱의제조방법에관한것이다.
Abstract translation: 本发明涉及使用桑叶和桑叶的加工品制备高品质功能性桑树和桑叶杨果（甜蜜果冻）的方法，其通过进行发酵过程或蒸煮过程而具有桑树和桑叶阳杨的双重功能和适口性， 与使用桑叶粉，桑叶粉，琼脂，糖和红豆酱制备的现有桑树和桑叶的方法不同的是焙烧过程。 更具体地说，本发明涉及一种制备桑树种子作为装饰品的桑蚕桑甘薯的制备方法，所述桑树种子在制备桑蚕醋时获得作为副产物生产的桑树种子，并且通过将粗精糖和寡糖加入到发酵桑果醋中而制备 桑树是桑树果实，在低温下熟化混合物以制备发酵桑兰昌和桑兰，并用酒精和乙酸发酵桑叶昌昌和桑兰昌，并制备了一种用于制备功能性桑叶的方法 通过蒸桑桑制备的樟子松提取物，热风烘干桑叶，获得桑叶粉末，烘焙桑叶粉末和樟树（桑树枝），并用水提取桑叶粉和樟子松 。
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17.发明授权항염증, 항노화 기능성 옥시레스베라트롤, 트란스-레스베라트롤 및 모라신이 함유된 뽕나무 가지추출물의 제조방법 有权氧化维甲醚，t-白藜芦醇和具有桑树枝提取物抗炎和抗衰老功能的莫沙星的制备方法
公开(公告)号：KR101438543B1
公开(公告)日：2014-09-18
申请号：KR1020120014928
申请日：2012-02-14
Applicant: 대구가톨릭대학교산학협력단 , 최상원
IPC: A61K36/605 , A61K36/60 , A61K31/045 , A61K31/05
Abstract: 본 발명은 항염증 및 항노화성 옥시레스베라트롤, 트란스-레스베라트롤 및 모라신 함유 뽕나무가지(상지)추출물의 제조방법에 관한 것으로, 상지를 찜처리한 후 건조하고 80% 에탄올수용액으로 추출하여 얻은 에탄올추출물을 pectinex 효소처리한 후 에틸아세테이트로 분획하고 농축한 후 최종 다이아이온 HP-20 흡착이온수지 칼럼 크로마토그래피를 실시하여 항염증성 및 항노화성 옥시레스베라트롤 (oxyresveratrol), 트란스-레스베라트롤(
trans -resveratrol) 및 모라신(moracin)을 함유하는 상지추출물을 제조하고, 이의 피부 염증 치료제 및 피부미백 기능성화장품 신소재용도를 개시한다.-
公开(公告)号：KR101340081B1
公开(公告)日：2013-12-11
申请号：KR1020120014927
申请日：2012-02-14
Applicant: 대구가톨릭대학교산학협력단 , 최상원
Abstract: 본 발명은 고혈압 뿐만 아니라 당뇨, 피부노화 억제용 플라보노이드 함유 뽕나무잎(상엽)추출물의 제조방법에 관한 것으로, 건조 상엽을 30% 에탄올수용액으로 추출하여 얻은 에탄올추출물을 다이아이온 HP-20 흡착이온수지 칼럼 크로마토그래피를 실시하여 항고혈압, 항당뇨 및 항노화성 퀘세틴 3-
O -(6"-
O -말로닐)-베타-디-글루코사이드(Q3MG) 및 캄페롤 3-
O -(6"-
O -말로닐)-베타-디-글루코사이드(K3MG)를 함유한 상엽추출물 I과 루틴(rutin, RT), 이소퀘시트린(isoquercitrin, IQT) 및 아스트라갈린(astragalin, AG)을 함유한 상엽추출물 Ⅱ를 제조하고 이를 이용하여 상엽으로부터 항고혈압, 항당뇨 및 항노화성 퀘세틴 및 캄페롤유도체를 대량생산과 고혈압, 당뇨 및 피부미백 기능성식품 및 화장품의 신소재의 용도를 개시한다.-
公开(公告)号：KR1020130104240A
公开(公告)日：2013-09-25
申请号：KR1020120025594
申请日：2012-03-13
Applicant: 대구가톨릭대학교산학협력단 , (주)에스.앤.디
IPC: A61K31/404 , A61K36/815 , A61P3/00
CPC classification number: A61K36/815 , A23V2200/326 , A61K2236/333
Abstract: PURPOSE: An anticholesterol composition is provided to suppress the activities of HMG-CoA reductase and acyl-CoA:cholesterol acyltransferase (ACAT) and to lower cholesterol in serum using a Lycii radicis cortex-derived tyramine derivative, thereby preventing hyperlipidemia. CONSTITUTION: A method for preparing an anticholesterol tyramine derivative comprises the steps of: extracting Lycii radicis cortex powder with an ethanol solution and filtering the extract; concentrating the extract by compression; and performing Sep-Pak C18 cartridges column chromatography. The derivative is trans-N-p-coumaroyltyramine (CT) or trans-N-feruloyltyramine (FT). A functional food composition for anticholesterol and antioxidative effects contains the tyramine derivative as an active ingredient.
Abstract translation: 目的：提供一种抗胆固醇组合物，以抑制HMG-CoA还原酶和酰基辅酶A：胆固醇酰基转移酶（ACAT）的活性，并使用雷公藤皮质衍生的酪胺衍生物降低血清中的胆固醇，从而预防高脂血症。 构成：制备抗胆固醇酪胺衍生物的方法，包括以下步骤：用乙醇溶液提取李子皮质粉末并过滤提取物; 通过压缩浓缩提取物; 并进行Sep-Pak C18柱色谱。 衍生物是反式-N-对 - 芳香酰酪氨酸（CT）或反式N-阿魏酰酪胺（FT）。 用于抗胆固醇和抗氧化作用的功能性食品组合物含有酪胺衍生物作为活性成分。
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公开(公告)号：KR1020130093371A
公开(公告)日：2013-08-22
申请号：KR1020120014927
申请日：2012-02-14
Applicant: 대구가톨릭대학교산학협력단 , 최상원
Abstract: PURPOSE: A production method of a mulberry leaf extract is provided to mass-produce refined powder containing flavonoid with the high value from mulberry leaves. CONSTITUTION: Mulberry leaves harvested in June are pre-dried in the shade for a week, and dried in a 45-55°C hot air drier for two days until the water content is 10 ± 3%. 100 kg of dried mulberry leaves is mixed with 650 kg of 30% ethanol solution for ultrasound extracting for 12 hours at 40-50°C, and the mixture is filtered and decompress-concentrated. The concentrate is dissolved in a 30% ethanol solution before settling for one night at room temperature, and centrifugal-separating precipitates. Supernatant is decompress-concentrated, and dissolved in a 20% ethanol solution. The concentrate passes through a Diaion HP-20 adsorption ion resin for absorbing flavonoid, and is eluted by 30% and 50% ethanol solutions. The silica gel and Sephadex column chromatography is conducted on each fraction successively. [Reference numerals] (AA) Mulberry leaves; (BB) Extraction (650 kg, 20% ethanol solution, ultrasound extractor, 50°C, 12 hours, 2 times); (CC) Filtration; (DD) Filtrate; (EE,JJ) Decompress-concentration; (FF) Mulberry leaf ethanol extract (23 kg); (GG) Re-dissolving (100 kg, 30% ethanol solution); (HH) Settling for one night; (II) Supernatant; (KK) Mulberry leaf ethanol extract (21.2 kg); (LL) Suspension (50 kg, 20% ethanol solution); (MM) Diaion HP-20 column chromatography; (NN) 30% ethanol solution fraction; (OO) 50% ethanol solution fraction; (PP) Mulberry extract I (1.1 kg); (QQ) Mulberry extract II (0.73 kg)
Abstract translation: 目的：提供桑叶提取物的生产方法，从桑叶中大量生产含有黄酮类化合物的精制粉末。 构成：6月份收获的桑叶在阴凉处预干燥一周，然后在45-55°C热空气干燥器中干燥两天，直到含水量为10±3％。 将100kg干桑叶与650kg 30％乙醇溶液混合，在40-50℃下超声提取12小时，将混合物过滤并减压浓缩。 将浓缩物溶解在30％乙醇溶液中，然后在室温下沉降一夜，然后离心分离沉淀。 上清液减压浓缩，溶于20％乙醇溶液。 浓缩物通过Diaion HP-20吸附离子树脂吸收黄酮，并被30％和50％乙醇溶液洗脱。 依次对各部分进行硅胶和Sephadex柱层析。 （附图标记）（AA）桑叶; （BB）提取（650kg，20％乙醇溶液，超声提取器，50℃，12小时，2次）; （CC）过滤; （DD）滤液; （EE，JJ）减压浓缩; （FF）桑叶乙醇提取物（23kg）; （GG）再溶解（100kg，30％乙醇溶液）; （HH）结算一晚; （二）上清液; （KK）桑叶乙醇提取物（21.2公斤）; （LL）悬浮液（50kg，20％乙醇溶液）; （MM）Diaion HP-20柱色谱; （NN）30％乙醇溶液级分; （OO）50％乙醇溶液级分; （PP）桑树提取物I（1.1kg）; （QQ）桑树提取物II（0.73公斤）
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