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11.发明公开
公开(公告)号：KR1020140064540A
公开(公告)日：2014-05-28
申请号：KR1020120131965
申请日：2012-11-20
Applicant: 대한민국(농촌진흥청장)
Abstract: The present invention relates to a fibrinogenase cel-KG26 gene derived from rumen microorganisms of a black goat and uses thereof, and more specifically, to a cel-KG26 gene which is a novel fibrinogenase selected from rumen microorganisms of a black goat and a method of providing protein products thereof and manufacturing feed additives, a detergent composition, and biofuel by using the same. According to the present invention, by selecting a cel-KG26 gene which is a novel fibrinogenase gene derived from the rumen microorganisms of a black goat and providing a fibrinogenase cel-KG26 gene and protein products therethrough, it can be used for developing low-priced feed additives, softener, and detergent and actively used for production of biofuel by decomposing fibrins which are rich sources.
Abstract translation: 本发明涉及一种来自黑山羊瘤胃微生物的纤维蛋白原酶cel-KG26基因及其用途，更具体地说，涉及一种选自黑山羊瘤胃微生物的新型纤维蛋白原酶的cel-KG26基因， 通过使用它们提供蛋白质产物和制造饲料添加剂，洗涤剂组合物和生物燃料。 根据本发明，通过选择作为来源于黑山羊的瘤胃微生物的新型纤维蛋白原酶基因的cel-KG26基因，通过其提供纤维蛋白原酶cel-KG26基因和蛋白质产物，可以用于开发低价位 饲料添加剂，软化剂和洗涤剂，并通过分解富集的纤维素积极地用于生产生物燃料。
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公开(公告)号：KR1020140052093A
公开(公告)日：2014-05-07
申请号：KR1020120108343
申请日：2012-09-27
Applicant: 전남대학교산학협력단 , 대한민국(농촌진흥청장)
IPC: C12N15/85 , C12N15/54 , A01K67/027
Abstract: The present invention relates to a knock-in vector that can target a complement regulatory protein (decay accelerating factor, DAF) gene and a human alpha 1,2-fucosyltransferase (HT) gene in a position of an alpha 1,3-galactosyl transferase (alpha 1,3-GT) gene, a cell transduced with the vector, a fertilized egg that is nuclear transplanted in the cell, a transgenic animal that is knocked out by the vector, and a method for producing the same. The knock-in vector of the present invention can be used to produce a transgenic animal in which hyperacute rejection that occurs in xeno-transplantation is controlled, so that the knock-in vector can be widely used for the production of a transgenic animal that can be used for effective xeno-transplantation.
Abstract translation: 本发明涉及可以靶向α1,3-半乳糖基转移酶位置的补体调节蛋白（衰变加速因子，DAF）基因和人α1,2-岩藻糖基转移酶（HT）基因的敲入载体 （α1T-GT）基因，用载体转导的细胞，被移植到细胞中的受精卵，被载体敲除的转基因动物及其制备方法。 本发明的敲入载体可用于产生其中控制异种移植中发生超急性排斥反应的转基因动物，使得敲入载体可广泛用于生产转基因动物，其可以 用于有效的异种移植。
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公开(公告)号：KR1020120047338A
公开(公告)日：2012-05-14
申请号：KR1020100101442
申请日：2010-10-18
Applicant: 대한민국(농촌진흥청장)
CPC classification number: A61K38/193 , C07K14/535 , Y10S514/824
Abstract: PURPOSE: A pharmaceutical composition containing human G-CSF mutant is provided to reduce administration amount and number. CONSTITUTION: A pharmaceutical composition for treating ischemic diseases contains the G-CSF mutant which is modified by substitution of 140th amino acid residue of human G-CSF, from phenylalanine(F) to asparagine(N). The human G-CSF is G-CSFb. The pharmaceutical composition further contains a carrier or excipient. The pharmaceutical composition also contains suspension, stabilizing agent, isotonizing agent, preservative, anti-adsorbing agent, surfactant, pH adjusting agent, analgesia agent, or anti-oxidant agent.
Abstract translation: 目的：提供含有人G-CSF突变体的药物组合物，以减少给药量和数量。 构成：用于治疗缺血性疾病的药物组合物含有通过将人G-CSF的第140位氨基酸残基从苯丙氨酸（F）取代为天冬酰胺（N）而被修饰的G-CSF突变体。 人G-CSF是G-CSFb。 药物组合物还含有载体或赋形剂。 药物组合物还含有悬浮液，稳定剂，等渗剂，防腐剂，抗吸附剂，表面活性剂，pH调节剂，镇痛剂或抗氧化剂。
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公开(公告)号：KR101890351B1
公开(公告)日：2018-10-01
申请号：KR1020160150622
申请日：2016-11-11
Applicant: 대한민국(농촌진흥청장) , 성균관대학교산학협력단
IPC: C07K16/18 , C12N15/74 , A23K10/18 , A61K35/747
Abstract: 본발명은생쥐의락토바실러스존스니및 이를이용한면역증진용조성물에관한것으로, 보다상세하게는, 항바이러스활성이있는최적화된단백질을생쥐유래유산균을운반체로하여항바이러스활성및 면역증진효과를동시에가지는형질전환된생쥐의락토바실러스존스니및 이를이용한면역증진용조성물에관한것이다.
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15.发明授权
公开(公告)号：KR101503856B1
公开(公告)日：2015-03-19
申请号：KR1020130073950
申请日：2013-06-26
Applicant: 대한민국(농촌진흥청장)
Abstract: 본 발명은 흑염소 반추위 미생물 유래의 자일라나아제 활성 효소 cel10-CBM6-KG60 유전자 및 이의 용도에 관한 것으로, 보다 구체적으로 흑염소 반추위 미생물로부터 선별한 신규한 자일라나아제 활성 효소 유전자인 cel10-CBM6-KG60 유전자 및 이의 단백질 산물을 제공하고, 이를 이용하여 사료첨가제, 세제 조성물 및 바이오연료를 제조하는 방법에 관한 것이다. 본 발명에 따르면, 흑염소 반추위 미생물로부터 신규한 자일라나아제 활성 효소 유전자인 cel10-CBM6-KG60 유전자를 선별할 수 있으며, 이를 통해 자일라나아제 활성 효소 cel10-CBM6-KG60 유전자 및 단백질 산물을 제공함으로써 저가의 사료 첨가제 개발에 이용할 수 있고, 섬유 유연제 및 세제 개발뿐만 아니라 풍부한 자원인 자일란을 분해하여 바이오연료의 생산에도 적극적으로 이용할 수 있다.
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Patent Agency Ranking
公开(公告)号：KR101437545B1
公开(公告)日：2014-09-11
申请号：KR1020120132027
申请日：2012-11-20
Applicant: 대한민국(농촌진흥청장)
Abstract: 본 발명은 흑염소 반추위 미생물 유래의 섬유소분해효소 cel-KG36 유전자 및 이의 용도에 관한 것으로, 보다 구체적으로 흑염소 반추위 미생물로부터 선별한 신규한 섬유소분해효소 유전자인 cel-KG36 유전자 및 이의 단백질 산물을 제공하고, 이를 이용하여 사료첨가제, 세제 조성물 및 바이오연료를 제조하는 방법에 관한 것이다.
본 발명에 따르면, 흑염소 반추위 미생물로부터 신규한 섬유소분해효소 유전자인 cel-KG36 유전자를 선별할 수 있으며, 이를 통해 섬유소분해효소 cel-KG36 유전자 및 단백질 산물을 제공함으로써 저가의 사료 첨가제 개발에 이용할 수 있고, 섬유 유연제 및 세제 개발뿐만 아니라 풍부한 자원인 섬유소를 분해하여 바이오연료의 생산에도 적극적으로 이용할 수 있다.-
公开(公告)号：KR101437571B1
公开(公告)日：2014-09-05
申请号：KR1020120131957
申请日：2012-11-20
Applicant: 대한민국(농촌진흥청장)
Abstract: 본 발명은 흑염소 반추위 미생물 유래의 섬유소분해효소 cel-KG11 유전자 및 이의 용도에 관한 것으로, 보다 구체적으로 흑염소 반추위 미생물로부터 선별한 신규한 섬유소분해효소 유전자인 cel-KG11 유전자 및 이의 단백질 산물을 제공하고, 이를 이용하여 사료첨가제, 세제 조성물 및 바이오연료를 제조하는 방법에 관한 것이다. 본 발명에 따르면, 흑염소 반추위 미생물로부터 신규한 섬유소분해효소 유전자인 cel-KG11 유전자를 선별할 수 있으며, 이를 통해 섬유소분해효소 cel-KG11 유전자 및 단백질 산물을 제공함으로써 저가의 사료 첨가제 개발에 이용할 수 있고, 섬유 유연제 및 세제 개발뿐만 아니라 풍부한 자원인 섬유소를 분해하여 바이오연료의 생산에도 적극적으로 이용할 수 있다.
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18.发明公开
公开(公告)号：KR1020140064576A
公开(公告)日：2014-05-28
申请号：KR1020120132030
申请日：2012-11-20
Applicant: 대한민국(농촌진흥청장)
Abstract: The present invention relates to a fibrinogenase cel-KG49 gene derived from rumen microorganisms of a black goat and uses thereof, and more specifically, to a cel-KG49 gene which is a novel fibrinogenase selected from rumen microorganisms of a black goat and a method of providing protein products thereof and manufacturing feed additives, a detergent composition, and biofuel by using the same. According to the present invention, a cel-KG49 gene which is a novel fibrinogenase gene derived from the rumen microorganisms of a black goat can be selected, and by providing the fibrinogenase cel-KG49 gene and protein products therethrough, they can be used for developing low-priced feed additives, softener, and detergent and actively used for production of biofuel by decomposing fibrins which are rich sources.
Abstract translation: 本发明涉及一种来自黑山羊瘤胃微生物的纤维蛋白原酶cel-KG49基因及其用途，更具体地说，涉及一种选自黑山羊瘤胃微生物的新型纤维蛋白原酶的cel-KG49基因， 通过使用它们提供蛋白质产物和制造饲料添加剂，洗涤剂组合物和生物燃料。 根据本发明，可以选择作为来自黑山羊的瘤胃微生物的新型纤维蛋白原酶基因的cel-KG49基因，通过提供纤维蛋白原酶cel-KG49基因和蛋白质产物，可以用于显影 低价饲料添加剂，软化剂和洗涤剂，并通过分解富集的纤维素积极地用于生产生物燃料。
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公开(公告)号：KR1020140064571A
公开(公告)日：2014-05-28
申请号：KR1020120132022
申请日：2012-11-20
Applicant: 대한민국(농촌진흥청장)
Abstract: The present invention relates to a fibrinogenase cel-KG25 gene derived from rumen microorganisms of a black goat and uses thereof, and more specifically, to a cel-KG25 gene which is a novel fibrinogenase selected from rumen microorganisms of a black goat and a method of providing protein products thereof and manufacturing feed additives, a detergent composition, and biofuel by using the same. According to the present invention, it is possible to select a cel-KG25 gene which is a novel fibrinogenase gene derived from the rumen microorganisms of a black goat, and by providing the fibrinogenase cel-KG25 gene and protein products therethrough, they can be used for developing low-priced feed additives, softener, and detergent and actively used for production of biofuel by decomposing fibrins which are rich sources.
Abstract translation: 本发明涉及来源于黑山羊瘤胃微生物的纤维蛋白原酶cel-KG25基因及其用途，更具体地说，涉及一种选自黑山羊的瘤胃微生物的新型纤维蛋白原酶的cel-KG25基因， 通过使用它们提供蛋白质产物和制造饲料添加剂，洗涤剂组合物和生物燃料。 根据本发明，可以选择作为来自黑山羊的瘤胃微生物的新型纤维蛋白原酶基因的cel-KG25基因，通过提供纤维蛋白原酶-KK25基因和蛋白质产物，可以使用它们 用于开发低价饲料添加剂，软化剂和洗涤剂，并通过分解富集的纤维素积极地用于生产生物燃料。
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20.发明公开
公开(公告)号：KR1020140064565A
公开(公告)日：2014-05-28
申请号：KR1020120132009
申请日：2012-11-20
Applicant: 대한민국(농촌진흥청장)
Abstract: The present invention relates to a fibrinogenase cel-KG48 gene derived from rumen microorganisms of a black goat and uses thereof, and more specifically, to a cel-KG48 gene which is a novel fibrinogenase gene selected from rumen microorganisms of a black goat and a method of providing protein products thereof and manufacturing feed additives, a detergent composition, and biofuel by using the same. According to the present invention, a cel-KG48 gene which is a novel fibrinogenase gene derived from the rumen microorganisms of a black goat can be selected, and by providing the fibrinogenase cel-KG48 gene and protein products therethrough, they can be used for developing low-priced feed additives, softener, and detergent and actively used for production of biofuel by decomposing fibrins which are rich sources.
Abstract translation: 本发明涉及来自黑山羊瘤胃微生物的纤维蛋白原酶cel-KG48基因及其用途，更具体地说，涉及一种选自黑山羊瘤胃微生物的新型纤维蛋白原酶基因cel-KG48基因 提供其蛋白质产物和制造饲料添加剂，洗涤剂组合物和使用它们的生物燃料。 根据本发明，可以选择作为来自黑山羊的瘤胃微生物的新型纤维蛋白原酶基因的cel-KG48基因，通过提供纤维蛋白原酶cel-KG48基因和蛋白质产物，可以用于显影 低价饲料添加剂，软化剂和洗涤剂，并通过分解富集的纤维素积极地用于生产生物燃料。
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