公开(公告)号：KR1020040056691A

公开(公告)日：2004-07-01

申请号：KR1020020083233

申请日：2002-12-24

Applicant: 임실생약영농조합법인

Inventor： 장선일 ,  김형진 ,  황기명 ,  제갈승주 ,  정헌택 ,  권태오 ,  김윤철 ,  윤용갑 ,  최병민 ,  배현옥 ,  심재석

IPC: A61K35/618

CPC classification number: A61K35/618

Abstract: PURPOSE: Provided is a pharmaceutical composition for treating liver diseases containing the extract of natural products with Semisulcospira libertina (Gould) extract as active ingredient. The composition has excellent inhibition effect on hepatic fibrosis. CONSTITUTION: A pharmaceutical composition for treating liver diseases is characterized by containing Semisulcospira libertina (Gould) extract as active ingredient and it further contains the extract of natural products selected from Artemisia Messerschmidtiana Besser, Hovenia dulcis Thumb, garlic, Paeonia japonica var. pilosa, Angelica gigas Nakai, Polygonatum odoratum Druce var., licorice root, jujube, cinnamon, dried ginger and Gardenia jasminoides Ellis.

Abstract translation: 目的：本发明提供一种含有半固体半乳糖（Goose）提取物作为有效成分的天然产物提取物治疗肝病的药物组合物。 该组合物对肝纤维化具有优异的抑制作用。 构成：用于治疗肝脏疾病的药物组合物的特征在于含有半透半乳皂苷（Gould）提取物作为活性成分，并且还含有选自蒿蒿，Ho is，大蒜，芍药的天然产物提取物。 茯苓，当归，中药，茯苓，甘草，枣，肉桂，干姜，栀子栀子。

公开(公告)号：KR3009169180000S

公开(公告)日：2017-08-16

申请号：KR3020160055553

申请日：2016-11-18

Applicant: 임실생약영농조합법인

Designer： 심재석

公开(公告)号：KR1020140119933A

公开(公告)日：2014-10-13

申请号：KR1020130034505

申请日：2013-03-29

Applicant: 임실생약영농조합법인

Inventor： 강현주 ,  김현수 ,  전인화 ,  목지예 ,  정승일 ,  심재석 ,  장선일

IPC: A61K36/28 ,  A61K36/287 ,  A61P19/02

Abstract: The present invention relates to a composition for alleviating arthritis, which is effective for alleviating rheumatic arthritis symptoms by comprising Cirsium japonicum var. ussuriense leap extracts, and more specifically, to a composition for alleviating arthritis, which is highly effective in alleviating arthritis by comprising Cirsium japonicum var. ussuriense leap extracts, significantly decreasing infiltration of not only inflammatory cell but also mast cell, inhibiting cytokine which induces inflammation such as PGE2, TNF-α, IL-6, and IL-4, and increasing IL-10 which is anti-inflammatory cytokine.

Abstract translation: 本发明涉及一种用于缓解关节炎的组合物，其通过包括日本um um属（Carisium japonicum var。）来减轻风湿性关节炎症状。 尤其是用于减轻关节炎的组合物，其通过包含日本um um变种来缓解关节炎是非常有效的。 ususuriense飞跃提取物，显着减少渗透不仅炎症细胞，而且肥大细胞，抑制细胞因子诱导炎症如PGE2，TNF-α，IL-6和IL-4，并增加IL-10是抗炎细胞因子 。

公开(公告)号：KR101373120B1

公开(公告)日：2014-03-13

申请号：KR1020120029136

申请日：2012-03-22

Applicant: 임실생약영농조합법인

Inventor： 정승일 ,  김상준 ,  장선일 ,  심재석 ,  김선영

IPC: A61K36/287 ,  A61K36/28 ,  A61P1/16

Abstract: 본 발명은 엉겅퀴 추출물을 함유함으로써 간성상세포의 활성화를 억제함으로써 만성 간질환을 예방 및 개선할 수 있는 조성물에 관한 것이다.

公开(公告)号：KR101352591B1

公开(公告)日：2014-01-22

申请号：KR1020120029135

申请日：2012-03-22

Applicant: 임실생약영농조합법인

Inventor： 장선일 ,  목지예 ,  강현주 ,  조정근 ,  전인화 ,  김현수 ,  박지민 ,  정승일 ,  심재석

IPC: A61K36/287 ,  A61K36/28 ,  A61P7/00

Abstract: 본 발명은 엉겅퀴 추출물을 함유함으로써 적혈구의 용혈을 억제하고 혈장의 산화적 손상을 보호하며 혈관 손상을 방지하여 혈행을 개선시킴으로써 신체 질환의 예방 및 개선이 가능한 조성물에 관한 것이다.

公开(公告)号：KR1020160059152A

公开(公告)日：2016-05-26

申请号：KR1020140160646

申请日：2014-11-18

Applicant: 임실생약영농조합법인

Inventor： 심재석 ,  김창수

IPC: A61K36/28 ,  A61P3/04 ,  A61P3/00

Abstract: 본발명은엉겅퀴() 잎열수추출물을유효성분으로함유하는항비만용조성물, 상기조성물을함유하는비만치료또는예방용약학조성물및 건강기능식품에관한것이다.

Abstract translation: 本发明涉及一种抗肥胖组合物，其包含日本蓟马的水热提取物作为活性成分，以及包含该组合物的药物组合物和保健功能性食品。

公开(公告)号：KR1020140119934A

公开(公告)日：2014-10-13

申请号：KR1020130034506

申请日：2013-03-29

Applicant: 임실생약영농조합법인

Inventor： 장선일 ,  강현주 ,  김현수 ,  전인화 ,  목지예 ,  심재석 ,  정승일

IPC: A61K36/28 ,  A61K36/287 ,  A61P9/10 ,  A61P9/00

Abstract: The present invention relates to a composition containing a thistle extract for preventing and alleviating ischemic stroke, and more specifically, to a composition for effectively alleviating symptoms of cerebral infraction by inhibiting generation of ischemic stroke such as cerebral infraction and transient ischemic attacks, alleviating the symptoms, and especially decreasing the size of cerebral infraction. The composition contains 0.5-20 wt% of the thistle extract based on the total weight of the composition.

Abstract translation: 本发明涉及含有用于预防和减轻缺血性中风的蓟提取物的组合物，更具体地，涉及通过抑制脑缺血发作和短暂性脑缺血发作等缺血性中风的产生来有效缓解脑梗死症状的组合物，减轻症状 ，特别是减少脑梗死的大小。 基于组合物的总重量，组合物含有0.5-20重量％的蓟提取物。

公开(公告)号：KR1020130107407A

公开(公告)日：2013-10-02

申请号：KR1020120029135

申请日：2012-03-22

Applicant: 임실생약영농조합법인

Inventor： 장선일 ,  목지예 ,  강현주 ,  조정근 ,  전인화 ,  김현수 ,  박지민 ,  정승일 ,  심재석

IPC: A61K36/287 ,  A61K36/28 ,  A61P7/00

Abstract: PURPOSE: A composition containing a Cirsium japonicum extract for improving blood circulation is provided to suppress hemolysis of erythrocytes, to protect oxidative damage to plasma, and to prevent blood vessel injuries, thereby improving blood circulation and preventing and treating diseases. CONSTITUTION: A composition for improving blood circulation contains 1-1000 mg/kg of a Cirsium japonicum extract. The composition is used for preventing hemolysis and oxidative damage to plasma. The composition is also used for treating thrombosis. The composition is a health food.

Abstract translation: 目的：提供含有用于改善血液循环的日本蓟马提取物的组合物，以抑制红细胞的溶血，保护血浆的氧化损伤，防止血管损伤，从而改善血液循环和预防和治疗疾病。 构成：用于改善血液循环的组合物含有1-1000mg / kg的日本蓟马提取物。 该组合物用于预防血浆溶血和氧化损伤。 该组合物也用于治疗血栓形成。 组合物是保健食品。

公开(公告)号：KR100823896B1

公开(公告)日：2008-04-21

申请号：KR1020070003919

申请日：2007-01-12

Applicant: 전북대학교산학협력단

Inventor： 심재석 ,  신동화 ,  김용석 ,  정평화

IPC: A23L1/202 ,  A23L1/20

CPC classification number: A23L11/20 ,  A23L7/25 ,  A23L33/16 ,  A23V2002/00 ,  A23V2250/2116

Abstract: A method of increasing isoflavone content by hydropriming and osmopriming treatment of soybeans consecutively is provided to increase the isoflavone content by 10 to 40% due to soybeans. The germinated soybeans with increased isoflavone content are used to manufacture high functional fermented soybeans. Soybeans are soaked in purified water at 20 to 25deg.C for 4 to 6hr, hydrated, soaked in inorganic salt solutions for 4 to 6hr and germinated at 20 to 25deg.C and 85% relative humidity for 24 to 48hr in an incubator to give germinated soybeans with increased isoflavone content. The inorganic salt is any one selected from NaCl, KNO3 or MgSO4. High functional fermented soybeans are obtained by steaming the germinated soybeans with increased isoflavone content at 121deg.C for 60min, cooling to 50deg.C, inoculating with 2% by volume of Bacillus subtilis cultures and fermenting at 40deg.C for 72hr.

Abstract translation: 提供了一种通过连续大豆水解和渗透渗透处理来增加异黄酮含量的方法，以将大豆的异黄酮含量提高10〜40％。 具有增加的异黄酮含量的发芽大豆用于制造高功能发酵大豆。 大豆在20〜25℃的纯水中浸泡4〜6小时，水合，浸泡于无机盐溶液中4〜6小时，并在培养箱中在20〜25℃，85％相对湿度下发酵24〜48小时， 具有增加的异黄酮含量的发芽大豆。 无机盐是选自NaCl，KNO 3或MgSO 4的任何一种。 通过将含有异黄酮含量的发芽大豆在121℃蒸煮60分钟，冷却至50℃，用2体积％的枯草芽孢杆菌培养物接种并在40℃下发酵72小时，获得高功能发酵大豆。

公开(公告)号：KR1020100087825A

公开(公告)日：2010-08-06

申请号：KR1020090006833

申请日：2009-01-29

Applicant: 전북대학교산학협력단

Inventor： 강형섭 ,  김성주 ,  전설희 ,  김기범 ,  김진상 ,  장선일 ,  심재석

IPC: A61K31/185 ,  A61K31/352 ,  A61K36/284 ,  A61P25/32

Abstract: PURPOSE: A hangover relieving agent containing a flavonoid and taurine is provided to ensure the synergic function of extracted flavonoid and taurine and to treat and prevent liver damage. CONSTITUTION: A hangover relieving agent contains a flavonoid and taurine extracted from Atractylodis Rhizoma alba, Puerariae Radix, Cyperi Rhizoma, Cinnamomi Cortex, Agastachis Herba, Alpinia officinarum, Hordei Fructus Germinatus, Caryophylli Flos, Aurantii nobilis Pericarpium, or Ginseng Radix rubra. The hangover relieving agent is used for treating or preventing a fatty liver, alcoholic liver disease, liver cirrhosis, or cholestasis.

Abstract translation: 目的：提供含有类黄酮和牛磺酸的宿醉缓解剂，以确保提取的黄酮和牛磺酸的协同作用，并治疗和预防肝损伤。 构成：宿醉缓解剂含有从白术，葛根，西葫芦，肉桂皮，藿香，高粱，山茱萸，天竺葵，天竺葵或人参蓝花提取的黄酮和牛磺酸。 宿醉缓解剂用于治疗或预防脂肪肝，酒精性肝病，肝硬化或胆​​汁郁积。