公开(公告)号：KR100823896B1

公开(公告)日：2008-04-21

申请号：KR1020070003919

申请日：2007-01-12

Applicant: 전북대학교산학협력단

Inventor： 심재석 ,  신동화 ,  김용석 ,  정평화

IPC: A23L1/202 ,  A23L1/20

CPC classification number: A23L11/20 ,  A23L7/25 ,  A23L33/16 ,  A23V2002/00 ,  A23V2250/2116

Abstract: A method of increasing isoflavone content by hydropriming and osmopriming treatment of soybeans consecutively is provided to increase the isoflavone content by 10 to 40% due to soybeans. The germinated soybeans with increased isoflavone content are used to manufacture high functional fermented soybeans. Soybeans are soaked in purified water at 20 to 25deg.C for 4 to 6hr, hydrated, soaked in inorganic salt solutions for 4 to 6hr and germinated at 20 to 25deg.C and 85% relative humidity for 24 to 48hr in an incubator to give germinated soybeans with increased isoflavone content. The inorganic salt is any one selected from NaCl, KNO3 or MgSO4. High functional fermented soybeans are obtained by steaming the germinated soybeans with increased isoflavone content at 121deg.C for 60min, cooling to 50deg.C, inoculating with 2% by volume of Bacillus subtilis cultures and fermenting at 40deg.C for 72hr.

Abstract translation: 提供了一种通过连续大豆水解和渗透渗透处理来增加异黄酮含量的方法，以将大豆的异黄酮含量提高10〜40％。 具有增加的异黄酮含量的发芽大豆用于制造高功能发酵大豆。 大豆在20〜25℃的纯水中浸泡4〜6小时，水合，浸泡于无机盐溶液中4〜6小时，并在培养箱中在20〜25℃，85％相对湿度下发酵24〜48小时， 具有增加的异黄酮含量的发芽大豆。 无机盐是选自NaCl，KNO 3或MgSO 4的任何一种。 通过将含有异黄酮含量的发芽大豆在121℃蒸煮60分钟，冷却至50℃，用2体积％的枯草芽孢杆菌培养物接种并在40℃下发酵72小时，获得高功能发酵大豆。

公开(公告)号：KR1020100087825A

公开(公告)日：2010-08-06

申请号：KR1020090006833

申请日：2009-01-29

Applicant: 전북대학교산학협력단

Inventor： 강형섭 ,  김성주 ,  전설희 ,  김기범 ,  김진상 ,  장선일 ,  심재석

IPC: A61K31/185 ,  A61K31/352 ,  A61K36/284 ,  A61P25/32

Abstract: PURPOSE: A hangover relieving agent containing a flavonoid and taurine is provided to ensure the synergic function of extracted flavonoid and taurine and to treat and prevent liver damage. CONSTITUTION: A hangover relieving agent contains a flavonoid and taurine extracted from Atractylodis Rhizoma alba, Puerariae Radix, Cyperi Rhizoma, Cinnamomi Cortex, Agastachis Herba, Alpinia officinarum, Hordei Fructus Germinatus, Caryophylli Flos, Aurantii nobilis Pericarpium, or Ginseng Radix rubra. The hangover relieving agent is used for treating or preventing a fatty liver, alcoholic liver disease, liver cirrhosis, or cholestasis.

Abstract translation: 目的：提供含有类黄酮和牛磺酸的宿醉缓解剂，以确保提取的黄酮和牛磺酸的协同作用，并治疗和预防肝损伤。 构成：宿醉缓解剂含有从白术，葛根，西葫芦，肉桂皮，藿香，高粱，山茱萸，天竺葵，天竺葵或人参蓝花提取的黄酮和牛磺酸。 宿醉缓解剂用于治疗或预防脂肪肝，酒精性肝病，肝硬化或胆​​汁郁积。

公开(公告)号：KR1020100033064A

公开(公告)日：2010-03-29

申请号：KR1020080092039

申请日：2008-09-19

Applicant: 전북대학교산학협력단 ,  임실생약영농조합법인

Inventor： 차연수 ,  심재석 ,  김숙영 ,  문연정 ,  최보람

IPC: A61K36/81 ,  A61P3/10

Abstract: PURPOSE: A composition for preventing or treating obesity or type 2 diabetes is provided to reduce body weight and epididymis fat and carnitine, neutral lipid and blood cholesterol. CONSTITUTION: A composition for preventing or treating obesity or type 2 diabetes contains Jerusalem artichoke powder or extract as an active ingredient. The Jerusalem artichoke extract is contained in 0.01-5.99 weight%(w/w) of total diet. The composition increases carnitine content in blood or liver. The carnitine is increased by high expression of carnitine palmitoyltransferase-I.

Abstract translation: 目的：提供一种预防或治疗肥胖或2型糖尿病的组合物，以减轻体重和附睾脂肪和肉碱，中性脂质和血液胆固醇。 构成：用于预防或治疗肥胖或2型糖尿病的组合物含有菊芋粉或提取物作为活性成分。 菊芋提取物含有0.01-5.99重量％（w / w）的总饮食。 该组合物增加血液或肝脏中的肉碱含量。 肉碱棕榈酰转移酶I的高表达增加肉碱。

公开(公告)号：KR1020090005678A

公开(公告)日：2009-01-14

申请号：KR1020070068881

申请日：2007-07-09

Applicant: 전북대학교산학협력단 ,  임실생약영농조합법인

Inventor： 신동화 ,  홍선표 ,  정은정 ,  심재석

IPC: A23L1/221 ,  A23L1/23

CPC classification number: A23L19/00 ,  A23L5/13 ,  A23V2002/00 ,  A23V2200/302

Abstract: A method for maturing and preparing the black garlic, and the black garlic prepared by the method are provided to reduce the maturation time of garlic and to improve productivity. A method for maturing and preparing the black garlic comprises the steps of putting the raw garlic whose skin is removed in a sterilization pot and steaming the garlic; and maturing the steamed garlic in a thermo-hygrostat to prepare the steamed black garlic. Preferably the raw garlic is steamed at a temperature of 100±1 deg.C for 10-15 min.

Abstract translation: 提供熟化和制备黑蒜的方法以及通过该方法制备的黑蒜减少大蒜的熟化时间并提高生产率。 一种成熟和制备黑蒜的方法包括以下步骤：将除去皮肤的生蒜放入灭菌锅中并蒸煮大蒜; 并将蒸的大蒜熟成恒温恒湿器，以制备蒸黑蒜。 优选将生蒜在100±1℃的温度下蒸10-15分钟。

公开(公告)号：KR101917822B1

公开(公告)日：2018-11-12

申请号：KR1020170081745

申请日：2017-06-28

Applicant: 임실생약영농조합법인 ,  전북대학교산학협력단

Inventor： 심재석 ,  김용석 ,  심동준

IPC: A23L33/00 ,  A23L29/00 ,  A23L33/105 ,  C12P17/06

Abstract: 본발명은KCCM 11322 균주를이용한 cirsimaritin이강화된엉겅퀴농축액의제조방법에관한것으로, 더욱상세하게는건조된엉겅퀴에정제수를투입한후 열수추출하여엉겅퀴추출액을준비하는단계와; 상기엉겅퀴추출액을멸균한다음냉각하는단계와; 상기냉각한엉겅퀴추출액에올리고당을첨가하여보당하는단계와; 상기보당한엉겅퀴추출액에균주락토바실러스플란타럼(KCCM 11322)를접종하는단계와; 상기균주를접종한엉겅퀴추출액을발효하여엉겅퀴발효액을제조하는단계와; 상기엉겅퀴발효액을여과한후, 농축기로감압농축하여엉겅퀴농축액을제조하는단계; 및상기엉겅퀴농축액에결정과당및 사과산을혼합하는단계;를포함하는것을특징으로하는KCCM 11322 균주를이용한 cirsimaritin이강화된엉겅퀴농축액의제조방법에관한것이다.

公开(公告)号：KR1020110054409A

公开(公告)日：2011-05-25

申请号：KR1020090111031

申请日：2009-11-17

Applicant: 전북대학교산학협력단 ,  임실생약영농조합법인

Inventor： 강형섭 ,  김성주 ,  박혜민 ,  전설희 ,  장선일 ,  심재석 ,  김선영

IPC: A61K36/539 ,  A61P25/32 ,  A61K36/288 ,  A61K36/185

Abstract: PURPOSE: A hangover-relieving agent containing flavonoid is provided to suppress ROS generation and to prevent apoptosis of hepatocytes. CONSTITUTION: A hangover-relieving agent containing flavonoid is prepared by adding 1-10 weight% of taurine to extract mixture of 5-10 weight% of Scutellaria baicalensis, 5-10 weight% of Taraxacum platycarpum, 10-20 weight% of Alnus japonica Steude, 5-15 weight% of Puerariae radix, 1-10 weight% of red ginseng, 1-10 weight% of malt, 1-10 weight% of Aurantii nobilis Pericarpium, 1-10 weight parts of Artemisiae capillaries herba, 1-5 weight% of Atractylodes macrocephala Koidzumi, and 1-5 weight% of Beckmannia syzigachne.

Abstract translation: 目的：提供含有类黄酮的宿醉缓解剂，以抑制ROS的产生并防止肝细胞凋亡。 构成：通过添加1-10重量％的牛磺酸来提取5-10重量％的黄芩，5-10重量％的蒲公英，10-20重量％的Al粳的混合物，制备含有黄酮的宿醉缓释剂 葛根5-15重量％，红参1-10重量％，麦芽1-10重量％，天竺葵1-10重量％，蒿青蒿1-10重量份， 5％（重量）白术（Atractylodes macrocephala Koidzumi）和1-5％（重量）的贝克曼氏菌属。