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公开(公告)号：KR101069906B1
公开(公告)日：2011-10-05
申请号：KR1020080065646
申请日：2008-07-07
Applicant: 재단법인 제주테크노파크
Abstract: 본발명의비짜루국화추출물또는이로부터얻은용매분획물은뛰어난항산화활성을나타내며, 기존에미백제로알려진 melasolv보다더욱높은멜라닌저해활성을보이고, NO 생성을억제하여항염증효과를가지는것으로확인되었다.
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公开(公告)号：KR1020090104519A
公开(公告)日：2009-10-06
申请号：KR1020080029970
申请日：2008-03-31
Applicant: 재단법인 제주테크노파크
CPC classification number: A61K8/97 , A61K36/25 , A61Q19/02 , Y10S514/844
Abstract: PURPOSE: A whitening cosmetic composition containing Rhombea extract is provided to suppress melanogenesis and tyrosinase activity and prevent skin aging. CONSTITUTION: A method for manufacturing Rhombea extract with activity of melanogenesis and inhibiting tyrosinase comprises: a step of washing Rhombea; a step of drying and pulverizing the Rhombea; a step of dropping organic solvent and filtering; a step of concentrating filtering liquid to obtain powder; and a step of fractioning the Rhombea extract with organic solvent.
Abstract translation: 目的：提供含有Rhombea提取物的美白化妆品，以抑制黑素生成和酪氨酸酶活性，并防止皮肤老化。 构成：制造具有黑色素生成活性和抑制酪氨酸酶活性的菱形提取物的方法，包括：洗涤菱角的步骤; 干燥和粉碎罗汉亚的一个步骤; 滴加有机溶剂并过滤的步骤; 浓缩过滤液以获得粉末的步骤; 和用有机溶剂分级罗氏提取物的步骤。
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公开(公告)号：KR1020090081287A
公开(公告)日：2009-07-28
申请号：KR1020080007278
申请日：2008-01-23
Applicant: 재단법인 제주테크노파크
IPC: A61K31/35 , A61K31/352 , A61K36/752 , A61P3/04
Abstract: A composition for preventing and treating obesity is provided to reduce the content of cholesterol and neutral lipid in blood and effectively prevent and treat obesity by reducing weight. A composition for preventing or treating obesity comprises a citrus extract or compound of the chemical formulas 1 to 4 isolated from the extract. The citrus extract is contained in 0.01 to 50 weight% based on the weight of total composition. The compound is contained in 0.001 to 50 weight% based on total weight.
Abstract translation: 提供了用于预防和治疗肥胖症的组合物，以减少血液中胆固醇和中性脂质的含量，并通过减轻重量来有效预防和治疗肥胖。 用于预防或治疗肥胖症的组合物包括从提取物中分离的柑橘提取物或化学式1至4的化合物。 基于总组合物的重量，柑橘提取物的含量为0.01至50重量％。 该化合物的含量占总重量的0.001〜50重量％。
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公开(公告)号：KR100898758B1
公开(公告)日：2009-05-25
申请号：KR1020070057318
申请日：2007-06-12
Applicant: 재단법인 제주테크노파크
Abstract: 본 발명은 항당뇨 활성을 나타내는 패과식물의 추출물에 관한 것이다.
본 발명의 패과식물 추출물은 패, 넓패 중 선택된 1종을 준비하여 세척한 후, 70 % 에탄올에 침적시키고 2 ~ 3 일동안 실온에서 교반하여 침출한 다음, 여과기로 여과하여 조추출물을 제조하고, 이 조추출물을 극성이 다른 용매인 n- 헥산, 에틸아세테이트, 부탄올을 이용해 순차적으로 분획하여 분획물을 제조하는 것으로 구성된다.
본 발명에 의해 패과식물 추출물이 유효성분으로 포함된 항당뇨용 조성물 및 항산화용 조성물이 제공된다.
또한, 본 발명에 의해 패과식물 추출물로부터 분리한 디플로르에토하이드록시카르마롤(Diphlorethohydroxycarmalol)이 유효성분으로 포함된 항당뇨용 조성물 및 항산화용 조성물이 제공된다.
패, 넓패, 항당뇨, 항산화, 추출-
公开(公告)号：KR101162761B1
公开(公告)日：2012-07-05
申请号：KR1020080007278
申请日：2008-01-23
Applicant: 재단법인 제주테크노파크
IPC: A61K31/35 , A61K31/352 , A61K36/752 , A61P3/04
Abstract: 본 발명은 비만 예방 또는 치료용 조성물에 관한 것으로, 구체적으로는 미성숙 감귤 추출물 또는 이로부터 분리한 리모시트린-3-글루코즈(limocitrin-3-glucose), 8-메톡시 퀘르세틴 3-오-[6”-(3”′-하이드록시-3”′-메틸-글루타로일)-베타-디-글루코피라노시드] (8-Methoxy Quercetin 3-
O -[6”-(3”'-hydroxy-3”'-methyl-glutaroyl)-
β -D-glucopyranoside]), 퀘르세틴3-오-[6”-(3”′-하이드록시-3”′-메틸-글루타로일)-베타-디-글루코피라노시드] (Quercetin 3-
O -[6”-(3”'-hydroxy-3”'-methyl-glutaroyl)-
β -D-glucopyranoside]) 및 5,6,7,8,3',4'-헥사메톡시퀘르세틴3-오-[6”-(3”'-하이드록시-글루타로일)-베타-디-글루코피라노시드](5,6,7,8,3',4'-HexaMethoxyQuercetin3-O-[6”-(3”'-hydroxy-3”'-methyl-glutaroyl)-β-D-glucopyranoside])로 이루어진 군으로부터 선택된 하나 이상의 화합물을 포함하는 비만 예방 또는 치료용 조성물에 관한 것이다. 또한, 본 발명은 상기 비만 예방 또는 치료용 조성물을 포함하는 약제학적 조성물 및 건강 기능성 식품에 관한 것이다.
온주밀감, 미성숙과, 비만-
Patent Agency Ranking
公开(公告)号：KR1020090020216A
公开(公告)日：2009-02-26
申请号：KR1020070084778
申请日：2007-08-23
Applicant: 재단법인 제주테크노파크
CPC classification number: A61K8/97 , A61K36/03 , A61K2236/333 , A61Q19/02 , Y10S514/844
Abstract: A whitening composition containing the extract of Dictyota is provided to improve the inhibitory activity of tyrosinase in the cell and inhibitory activity of melanin formation, so that the composition is usable for the functional cosmetics. The whitening composition contains the extract of Dictyota which is prepared by washing the brown algae of Dictyota with the flowing water; drying the brown algae of Dictyota at 40 deg. C for 3 days and pulverizing it; extracting the pulverized product with 70% ethanol at room temperature for 2-3 days; filtering the extract; repeating the extracting and filtering process 2-3 times; concentrating the filtered solution under reduced pressure, and freeze-drying the concentrate to prepare the crude extract; and fractionating the crude extract with solvent having different polarity sequentially.
Abstract translation: 提供含有Dictyota提取物的增白组合物，以改善酪氨酸酶在细胞中的抑制活性和黑色素形成的抑制活性，使得该组合物可用于功能性化妆品。 美白组合物含有Dictyota的提取物，其通过用流动的水洗涤Dictyota的棕色藻类而制备; 在40度干燥Dictyota的棕色藻类。 C 3天，粉碎; 用70％乙醇在室温下萃取粉碎产物2-3天; 过滤提取物; 重复提取和过滤2-3次; 在减压下浓缩过滤的溶液，并冷冻干燥浓缩物以制备粗提取物; 并用依次具有不同极性的溶剂对粗提物进行分馏。
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公开(公告)号：KR1020130107947A
公开(公告)日：2013-10-02
申请号：KR1020120030154
申请日：2012-03-23
Applicant: 제주대학교 산학협력단 , 재단법인 제주테크노파크
IPC: A61K31/357 , A61K31/36 , A61K36/03 , A61P25/28
Abstract: PURPOSE: A composition containing diphlorethohydroxycarmalol compounds as active ingredients for protecting nerve cells is provided to prevent or treat brain diseases caused by glutamate neurotoxicity and to be used in functional foods for treating brain diseases. CONSTITUTION: A composition for protecting nerve cells contains diphlorethohydroxycarmalol compounds of chemical formula as active ingredients. The compound is derived from Ishigeaceae plants. The compound suppresses neurotoxicity caused by glutamate and activation of microglial cells. The compound prevents or treats brain diseases caused by glutamate neurotoxicity.
Abstract translation: 目的：提供一种含有双缓冲羟基卡马洛尔化合物作为保护神经细胞的有效成分的组合物，用于预防或治疗由谷氨酸神经毒性引起的脑部疾病，并用于治疗脑部疾病的功能性食品。 构成：用于保护神经细胞的组合物含有化学式的双倍亮氨酸羟基卡马洛尔化合物作为活性成分。 该化合物衍生自石ae科植物。 该化合物抑制谷氨酸引起的神经毒性和小胶质细胞的活化。 该化合物预防或治疗由谷氨酸神经毒性引起的脑部疾病。
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公开(公告)号：KR101042005B1
公开(公告)日：2011-06-16
申请号：KR1020090090696
申请日：2009-09-24
Applicant: 재단법인 제주테크노파크
IPC: C07C43/205 , A61K8/33 , A61K8/97 , A61Q19/02
Abstract: 본 발명은 비목나무 유래 화합물, 이의 분리 방법 및 이를 함유하는 피부 미백용 조성물에 관한 것으로, 더욱 상세하게는 비목나무(
Lindera erythrocarpa ) 추출물의 용매 분획물로부터 분리한 화합물과 이의 분리 방법 및 상기 화합물을 함유함으로써 멜라닌 생합성을 억제할 수 있는 피부 미백용 조성물에 관한 것이다.
페닐프로판(phenylpropane) 화합물, 비목나무, 추출물, 용매분획, 미백, 멜라닌, 티로시나제-
19.发明公开비목나무 추출물, 이의 분획물, 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 약학적 조성물 有权包含LINDERA ERYTHROCARPA提取物，其分类或其分离的化合物的药物组合物
公开(公告)号：KR1020110050397A
公开(公告)日：2011-05-13
申请号：KR1020100110687
申请日：2010-11-08
Applicant: 재단법인 제주테크노파크
Abstract: PURPOSE: A composition containing Lindera erythrocarpa extract, fraction, or compounds isolated from the extract and fraction is provided to prevent or treat cancer, arteriosclerosis, rheumatoid arthritis, multiple sclerosis, Alzheimer's disease, or obesity. CONSTITUTION: A pharmaceutical composition for preventing or treating cancer, arteriosclerosis, rheumatoid arthritis, multiple sclerosis, Alzheimer's disease, or obesity contains Lindera erythrocarpa extract, fraction or compounds isolated form the extract or fraction as an active ingredient. The Lindera erythrocarpa extract is isolated using water, C1-C4 alcohol, or mixture solvent thereof.
Abstract translation: 目的：提供含有从提取物和级分分离的Lindera erythrocarpa提取物，级分或化合物的组合物，以预防或治疗癌症，动脉硬化，类风湿性关节炎，多发性硬化，阿尔茨海默氏病或肥胖症。 构成：用于预防或治疗癌症，动脉硬化症，类风湿性关节炎，多发性硬化症，阿尔茨海默病或肥胖症的药物组合物含有从提取物或级分分离形成的作为活性成分的林德拉红果提取物，级分或化合物。 使用水，C1-C4醇或其混合溶剂分离林德拉红果提取物。
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20.发明公开
公开(公告)号：KR1020100028440A
公开(公告)日：2010-03-12
申请号：KR1020080087480
申请日：2008-09-04
Applicant: 재단법인 제주테크노파크
Abstract: PURPOSE: A composition for skin whiteing containing Lindera erythrocarpa extract or fraction and compound derived from Lindera erythrocarpa is provided to suppress melanin and ensure excellent whitening effects. CONSTITUTION: A composition for skin whitening contains Lindera erythrocarpa extract and solvent fraction thereof. The Lindera erythrocarpa extract is ethanol extract. The solvent fraction is hexane, methylene chloride, ethyl acetate, butanol, water or complex. The composition for skin whitening contains cyclpentadione compound as an active ingredient. The cyclepentadion is quercitrin, kaempferol-3-O-rhamnopyranoside, quercetin-3-O-arabinofuranoside, caffeic acid ethyl ester, cinamic acid methyl ester, lucidone, methyl linderone, or kanakugiol.
Abstract translation: 目的：提供含有Lindera erythrocarpa提取物或级分的衍生自Lindera erythrocarpa的皮肤白化组合物以抑制黑色素并确保优异的美白效果。 构成：用于皮肤美白的组合物含有Lindera erythrocarpa提取物及其溶剂级分。 Lindera erythrocarpa提取物是乙醇提取物。 溶剂馏分为己烷，二氯甲烷，乙酸乙酯，丁醇，水或络合物。 用于皮肤美白的组合物含有环戊二酮化合物作为活性成分。 槲皮素是槲皮素，山奈酚-3-O-鼠李糖吡喃糖苷，槲皮素-3-O-阿拉伯呋喃糖苷，咖啡酸乙酯，肉桂酸甲酯，荧光酮，甲基哌啶酮或者kanakugol。
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