비목나무 유래 화합물, 이의 분리 방법 및 이를 함유하는 피부 미백용 조성물
    3.
    发明公开
    비목나무 유래 화합물, 이의 분리 방법 및 이를 함유하는 피부 미백용 조성물 有权
    来自LINDERA ERYTHROCARPA的化合物,其分离方法和包含其的皮肤白化组合物

    公开(公告)号:KR1020110032931A

    公开(公告)日:2011-03-30

    申请号:KR1020090090696

    申请日:2009-09-24

    Abstract: PURPOSE: A Lindera erythrocarpa-derived compound is provided to obtain a composition for skin whitening showing melanin inhibitory activity higher than existing albutin known as a whitening agent. CONSTITUTION: A method for separating a Lindera erythrocarpa-derived compound comprises the steps of: extracting Lindera erythrocarpa in a solvent to obtain Lindera erythrocarpa extracts; partitioning the Lindera erythrocarpa extracts into hexane, methylene chloride, ethyl acetate, and butanol to obtain solvent fractions; partitioning the Lindera erythrocarpa extracts by performing a primary silicagel column chromatography using hexane and ethyl acetate as a solvent; and applying a secondary silica gel column chromatography to the extracts using a mixed solvent of hexane and ethyl acetate.

    Abstract translation: 目的:提供一种来源于林德拉克罗car甙的化合物,以获得一种皮肤美白组合物,其显示比已知的作为增白剂的已有的琥珀酸高的黑色素抑制活性。 构成:分离林多鱼赤藓醇衍生化合物的方法,包括以下步骤:在溶剂中提取枸杞子,获得枸杞子赤芍提取物; 将Lindera erythrocarpa提取物分配到己烷,二氯甲烷,乙酸乙酯和丁醇中,得到溶剂级分; 通过使用己烷和乙酸乙酯作为溶剂进行初级硅胶柱色谱法分离林德罗氏赤霉素提取物; 并使用己烷和乙酸乙酯的混合溶剂,在萃取液中进行二次硅胶柱色谱。

    비목나무 추출물, 이의 분획물, 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 약학적 조성물
    5.
    发明公开
    비목나무 추출물, 이의 분획물, 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 약학적 조성물 有权
    包含LINDERA ERYTHROCARPA提取物,其分类或其分离的化合物的药物组合物

    公开(公告)号:KR1020110050397A

    公开(公告)日:2011-05-13

    申请号:KR1020100110687

    申请日:2010-11-08

    Abstract: PURPOSE: A composition containing Lindera erythrocarpa extract, fraction, or compounds isolated from the extract and fraction is provided to prevent or treat cancer, arteriosclerosis, rheumatoid arthritis, multiple sclerosis, Alzheimer's disease, or obesity. CONSTITUTION: A pharmaceutical composition for preventing or treating cancer, arteriosclerosis, rheumatoid arthritis, multiple sclerosis, Alzheimer's disease, or obesity contains Lindera erythrocarpa extract, fraction or compounds isolated form the extract or fraction as an active ingredient. The Lindera erythrocarpa extract is isolated using water, C1-C4 alcohol, or mixture solvent thereof.

    Abstract translation: 目的:提供含有从提取物和级分分离的Lindera erythrocarpa提取物,级分或化合物的组合物,以预防或治疗癌症,动脉硬化,类风湿性关节炎,多发性硬化,阿尔茨海默氏病或​​肥胖症。 构成:用于预防或治疗癌症,动脉硬化症,类风湿性关节炎,多发性硬化症,阿尔茨海默病或肥胖症的药物组合物含有从提取物或级分分离形成的作为活性成分的林德拉红果提取物,级分或化合物。 使用水,C1-C4醇或其混合溶剂分离林德拉红果提取物。

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