Abstract:
The present invention provides a pharmaceutical composition or a functional health food for controlling angiogenesis, wherein trans-farnesol is included as an active ingredient. The trans-farnesol of the present invention controls the proliferation of vascular endothelial cells and the generation of tubes to control angiogenesis, thereby angiogenesis-related diseases can be prevented and treated.
Abstract:
The present invention relates to a composition containing Allyl isothiocyanate as an active ingredient for preventing and treating angiogenesis. According to the present invention, the Allyl isothiocyanate has an excellent effect in inhibiting angiogenesis, thereby being used as the active ingredient in a pharmaceutical composition and health functional food for preventing and treating angiogenesis. [Reference numerals] (AA,CC,GG,KK) Normal group; (BB,DD,HH,LL) Control group; (EE,II,MM) Experimental group 1; (FF,JJ,NN) Experimental group 2
Abstract:
본 발명은 어랩틴(Auraptene)을 유효성분으로 함유하는 신생혈관 촉진용 약학조성물에 관한 것으로, 본 발명에 의한 신생혈관 촉진용 약학조성물은 유효성분인 어랩틴에 의해 혈관 신생을 촉진시켜 피부판 재생, 상처 및 화상치유, 인공피부이식 및 이식용 혈관 제조 등의 조직 재생에 효과적이다.
Abstract:
PURPOSE: A pharmaceutical composition and health functional food containing thienylbutyl isothiocyanate are provided to inhibit adipocyte differentiation. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity and lipid-related metabolic disorders contains 0.1-50 wt% of thienylbutyl isothiocyanate as an active ingredient. The composition is administered in 0.01-500 mg/kg. The composition is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, oral administration, external use formulation, suppository, or sterilized injection solution. A health functional for preventing and relieving obesity and lipid-related metabolic diseases contains the thienyl butyl isothiocyanate as an active ingredient. The health functional food is manufactured in the form of capsules, tablets, granules, powder, or beverage.
Abstract:
PURPOSE: A method for detecting a marker contained in a biological sample is provided to diagnose and treat obesity or obesity-associated diseases. CONSTITUTION: A method for detecting a marker contained in a biological sample for diagnosing obesity comprises a step of detecting the concentration of arginine, tyrosine, pipecolic acid, benzoic acid, pantothenic acid, uric acid, phenyl acetamide, serotonin, L-carnitine, decanoyl carnitine, myristoyl carnitine, hexadekenoyl carnitine, linoleyl carnitien, vacenyl carnitine, stearoyl carnitine, lysoPC(C14:0), lysoPC(C15:0), lysoPC(C16:0), lysoPC(C16:1), lysoPC(C17:0), lysoPC(C17:1), lysoPC(C18:0), lysoPC(C18:1), lysoPC(C18:2), lysoPC(C18:3), lysoPC(C19:0), lysoPC(C20:1), lysoPC(C20:4), lysoPC(C20:5), lysoPE(C18:2), lysoPE(C20:4) or PCs marker in blood or glucose, glycerol, tyrosine, valine, 7-ketodeoxy cholic acid, and betain, L-carnitine, plamitic acid, linoleic acid, oleic acid, stearic acid, lysoPC(C14:0), lysoPC(C16:0), lysoPC(C16:1), lysoPC(C18:0), lysoPC(C18:3), lysoPC(C20:4), lysoPC(C22:6), or PCs in liver tissue.
Abstract:
PURPOSE: A composition containing Chelidonium majus var asiaticum extract is provided to activate AMPK(5'AMP-activated protein kinase) and to ensure antiobesity. CONSTITUTION: A composition for preventing and treating obesity contains 0.1-99.9 wt% of Chelidonium majus var asiaticum extract as an active ingredient. The composition is a pharmaceutical composition or food additive composition. The food composition for preventing and treating obesity contains the extract as an active ingredient. The extract is a hot water extract or ethanol extract. The composition is manufactured in the form of beverage, gum, tea, vitamin complex, pill, powder, granule, tablet, or capsule.
Abstract translation:目的:提供含有Chelidonium majus var asiaticum提取物的组合物以激活AMPK(5'AMP-活化的蛋白激酶)并确保抗肥胖。 构成:用于预防和治疗肥胖症的组合物含有0.1-99.9wt%的Chelidonium majus var asiaticum提取物作为活性成分。 该组合物是药物组合物或食品添加剂组合物。 用于预防和治疗肥胖症的食物组合物含有提取物作为活性成分。 提取物是热水提取物或乙醇提取物。 该组合物以饮料,口香糖,茶叶,维生素复合物,丸剂,粉末,颗粒,片剂或胶囊的形式制成。
Abstract:
PURPOSE: A composition containing 3-methyladenine is provided to decompose neutral lipid into glycerol and free fatty acid and to prevent or treat obesity, diabetes, and hyperlipidemia. CONSTITUTION: A pharmaceutical composition for preventing or treating obesity contains 3-methyladenien as an active ingredient. 3-methyladenine decomposes neutral lipid into glycerol and free fatty acid. A food composition for preventing or treating obesity contains 3-methyladenine as an active ingredient. The composition is used for preventing or treating obesity-associated metabolic diseases including diabetes, arteriosclerosis, metabolic diseases, and hyperlipidemia. The pharmaceutical composition is manufactured in the form of a liquid formulation or parenteral formulation.
Abstract:
PURPOSE: A composition containing genistein or pharmacologically acceptable salt thereof is provided to suppress fractalkine expression and vascular inflammation. CONSTITUTION: A composition for treating vasculitis caused by fractalkine expression contains 1-10 wt% of genistein or pharmacologically acceptable salt thereof as an active ingredient. The composition is a pharmaceutical composition or food additive composition. The composition also contains NF-kappaB inhibitor and p38 inhibitor or PI3'-K inhibitor in a weight ratio of 1:10-10:1.