中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

29 records (took 0.021 seconds)

    15.
    发明专利
    未知

    公开(公告)号：SE431208B

    公开(公告)日：1984-01-23

    申请号：SE8008533

    申请日：1980-12-04

    Applicant: ABBOTT LAB

    Inventor： WINN M ,  KYNCL J ,  DUNNIGAN D A ,  JONES P H

    IPC: C07D405/12 ,  A61K31/505 ,  A61P9/12 ,  A61P25/04 ,  C07D309/08 ,  C07D405/14

    Abstract: Described are antihypertensive agents selected from the class consisting of 2[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-[4(tetrahydropyran-2-carbonyl)-piperazinyl]-4-amino-6,7-dimethoxyqui nazoline, and pharmaceutically acceptable acid addition salts thereof. The compounds are highly water soluble and can be administered in time release form as well as parenterally, including intravenously.

    HETEROCYCLIC ESTERS OF ALKYLPHENYL BENZOPYRANS
    16.
    发明专利
    HETEROCYCLIC ESTERS OF ALKYLPHENYL BENZOPYRANS 未知

    公开(公告)号：PH13583A

    公开(公告)日：1980-07-16

    申请号：PH15684

    申请日：1974-04-02

    Applicant: ABBOTT LAB

    Inventor： WINN M

    IPC: C07C37/055 ,  C07D295/14 ,  C07D295/15 ,  C07D311/80 ,  C07D311/94 ,  C07D405/12 ,  C07D311/00 ,  C07D311/04

    Abstract: Heterocyclic esters of benzopyrans represented by the formula wherein n is 1 or 2; each R and R1 are the same or different members of the group consisting of hydrogen or loweralkyl; R2 is loweralkyl; R3 is WITH Y' being a straight or branched chain alkylene group having from one to eight carbon atoms, a is an integer from 1 to 4, b is an integer from 1 to 4, X is CH2, O, S or NR7 with R7 being hydrogen or loweralkyl, with the limitation that when X is O, S, or NR7, a and b each must be 2; R8 is hydrogen or loweralkyl; Y is a straight or branched chain alkylene group having from one to ten carbon atoms; and each R4 and R5 and R6 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl; and the pharmaceutically acceptable salts thereof.

    ALKYLPHENYL BENZOPYRAN DERIVATIVE,PHARMACEUTICAL COMPOSITION AND METHOD OF USE THEREOF
    18.
    发明专利
    ALKYLPHENYL BENZOPYRAN DERIVATIVE,PHARMACEUTICAL COMPOSITION AND METHOD OF USE THEREOF 未知

    公开(公告)号：PH12327A

    公开(公告)日：1979-01-16

    申请号：PH15681

    申请日：1974-04-01

    Applicant: ABBOTT LAB

    Inventor： LYNN K ,  WINN M ,  MARTIN Y

    IPC: C07C37/055 ,  C07D213/30 ,  C07D213/50 ,  C07D311/80 ,  C07D311/94 ,  C07D311/00

    Abstract: 1459564 Derivatives of dibenzopyran and cyclopentabenzopyran ABBOTT LABORATORIES 1 April 1974 [2 April 1973 13 Feb 1974] 14404/74 Heading C2C The invention comprises compounds of formulµ and the pharmaceutically acceptable salts of (I), (II) and (III), wherein n is 1 or 2; R and R 1 are each H or C 1-6 alkyl [but in the pyrone compound (XIII), H or Me]; R 2 is C 1-6 alkyl; Y is C 1-10 alkylene; R 4 , R 5 , R 6 are each H, halogen, CF 3 or C 1-6 alkyl; and Z is C or N. In examples, (XIII) are prepared by reacting an ethyl cyclopentanone (or cyclohexanone)-2-carboxylate with an appropriate 5-aralkylresorcinol (A), and converted into (I) and (II) by reaction with R 2 MgBr, followed optionally by hydrogenation to give (III). Starting materials prepared are the dimethyl ethers of (A), the benzene compounds where Q is CH : CHCO 2 H, CH 2 CH 2 CO 2 H, (CH 2 ) 3 OH, (CH 2 ) 3 Br, (CH 2 ) 5 OH and (CH 2 ) 3 Br, and the compounds 3,5-(MeO) 2 C 6 H 3 CR 0 R 0 - alkylene-Ar where CR 0 R 0 is CO or one R‹ is Me and the other is OH, and Ar is R 4 R 5 R 6 C 5 HZ-. Therapeutic compositions for oral, parenteral or rectal administration comprise the above compounds (Ia), which are analgesics, mild tranquillizers and antidiarrhoeals.

    19.
    发明专利
    未知

    公开(公告)号：SE7611379L

    公开(公告)日：1977-04-15

    申请号：SE7611379

    申请日：1976-10-13

    Applicant: ABBOTT LAB

    Inventor： WINN M ,  KYNCL J ,  DUNNIGAN D A ,  JONES P H

    IPC: C07D405/12 ,  A61K31/505 ,  A61P9/12 ,  A61P25/04 ,  C07D309/08 ,  C07D405/14

    Abstract: Described are antihypertensive agents selected from the class consisting of 2[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-[4(tetrahydropyran-2-carbonyl)-piperazinyl]-4-amino-6,7-dimethoxyqui nazoline, and pharmaceutically acceptable acid addition salts thereof. The compounds are highly water soluble and can be administered in time release form as well as parenterally, including intravenously.

Patent Agency Ranking