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    Use of sulfur containing compound, as a peroxide composite, in cosmetic and pharmaceutical agent to treat skin
    14.
    发明专利
    Use of sulfur containing compound, as a peroxide composite, in cosmetic and pharmaceutical agent to treat skin 未知

    公开(公告)号：DE102005022292A1

    公开(公告)日：2006-11-16

    申请号：DE102005022292

    申请日：2005-05-13

    Applicant: BASF AG

    Inventor： KROLL MANFRED ,  WAGENBLAST GERHARD ,  PTOCK ARNE ,  HAREMZA SYLKE ,  JENTZSCH AXEL

    IPC: A61K8/49 ,  A61K8/06 ,  A61K8/46 ,  A61Q17/00 ,  A61Q19/08

    Abstract: Use of sulfur containing compound (A), as a peroxide composite in cosmetic and pharmaceutical agent to treat skin. Use of sulfur containing compound (A) of formula ([Z 1>-N=C(Z 2>)-S] n-R 1>), (Z 1>-N(R 2>)-C(Z 2>)=S) or (Z 1>-S-C(Z 2>)=S), as a peroxide composite in cosmetic and pharmaceutical agent to treat skin. Either Z 1>, Z 2>organyl residue H; or Z 1>+Z 2>a bivalent group with 1-5 atoms between the flanking compound; R 1>H, alkyl, (hetero)cycloalkyl, (hetero)aryl or n-valent cation; R 2>H, alkyl, (hetero)cycloalkyl, (het)aryl, COOR-a, COO-M +>, SO 3R-a, SO 3-M +>, sulfone amide, NE 1>E 2>, (NE 1>E 2>E 3>) +>A ->, OR-a, SR-a, (CHR-bCH 2O) yR-a, (CH 2O) yR-a, (CH 2CH 2NE 1>) yR-a, (di)alkylaminocarbonyl, alkylcarbonylamino or acyl; R-a : resembles in each case or different remainders, H, alkyl, cycloalkyl, (het)aryl; E 1>-E 3>H, alkyl, cycloalkyl or (hetro)aryl; R-b : H, methyl or ethyl; M +>cation equivalent stands; A ->equivalent anion; y : 1-250; and n : 1-3. Independent claims are included for a cosmetic or pharmaceutical agent to treat skin to avoid or reduce damage of the skin, as a result of peroxide formed by endogenic or exogenous factors and/or hydroperoxide, comprising at least a peroxide composite, optionally at least an antioxidant that is effective as radical catcher. ACTIVITY : Dermatological; Antiseborrheic; Antiinflammatory; Antiallergic; Immunosuppressive. MECHANISM OF ACTION : None given.

    16.
    发明专利
    未知

    公开(公告)号：BR0311563A

    公开(公告)日：2005-04-26

    申请号：BR0311563

    申请日：2003-07-16

    Applicant: BASF AG

    Inventor： JENTZSCH AXEL ,  HABICH ANDREAS ,  KOPSEL CHRISTIAN ,  ERNST ANDREAS

    IPC: A23L33/15 ,  A23L33/155 ,  A61K8/67 ,  A61Q1/02 ,  A61Q17/04 ,  A61Q19/00 ,  A61K7/48 ,  A61K7/42 ,  A61K7/02

    Abstract: Preparations comprising at least one retinoid, at least one water-soluble antioxidant and at least one oil-soluble antioxidant, where, per part by weight of retinoid, at least 1 part by weight of one or more water-soluble antioxidants and 0.1 to 100 parts by weight of one or more oil-soluble antioxidants are present in the preparations, where the content of one or more water-soluble antioxidants is in the range from 0.05 to 0.8% by weight, based on the total amount of the preparations.

    Cosmetic preparations containing new or known 4-oxoretinol compounds, useful for prophylaxis of aging of the skin or hair
    19.
    发明专利
    Cosmetic preparations containing new or known 4-oxoretinol compounds, useful for prophylaxis of aging of the skin or hair 未知

    公开(公告)号：DE10010814A1

    公开(公告)日：2001-09-13

    申请号：DE10010814

    申请日：2000-03-08

    Applicant: BASF AG

    Inventor： JENTZSCH AXEL ,  ERNST HANSGEORG ,  STREICHER HARALD ,  KLEIN DANIELA

    IPC: A61K8/35 ,  A61K8/67 ,  A61Q5/00 ,  A61Q17/00 ,  A61Q19/08 ,  C07C403/16 ,  C07D311/58 ,  C07D311/72 ,  A61K7/00 ,  A61K7/06 ,  A61K7/48

    Abstract: The use of 4-oxo-retinol compounds (I) (including the free alcohol and ether, ester or carbonate derivatives) in cosmetic preparations is new. Some of (I) are new compounds. The use of 4-oxo-retinol compounds (I) in cosmetic preparations is new. [Image] R : H, 1-12C alkyl, 1-20C acyl, 1-12C alkoxycarbonyl, amino acid residue or tocopherol derivative residue of formula (i). [Image] Independent claims are included for: (1) cosmetic preparations for protecting the human epidermis or hair, comprising an effective amount of (I) in a carrier; and (2) (I; R = R') as new compounds. R' : 1-12C alkoxycarbonyl, amino acid residue or group (i). - ACTIVITY : Dermatological; antiseborrheic; antiinflammatory; antiallergic; immunosuppressive. - MECHANISM OF ACTION : Radical scavenger; antioxidant; regulation of collagen, hyaluronic acid or elastin synthesis; stimulation of DNA synthesis; regulation of transcription and translation of matrix-degrading enzymes (especially matrix metalloproteases); promotion of cellular renewal and regeneration of the skin; stimulation of intrinsic DNA, lipid and/or protein protection and repair mechanisms in the skin.

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