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公开(公告)号:JPH1087659A
公开(公告)日:1998-04-07
申请号:JP22474097
申请日:1997-08-21
Applicant: BASF AG
Inventor: ROSENAU THOMAS , HABICHER WOLF-DIETER , STREICHER HARALD
IPC: A23L1/30 , A23L33/15 , A61K8/00 , A61K8/49 , A61K8/67 , A61K31/35 , A61K31/375 , A61P43/00 , A61Q19/00 , C07D407/12 , C07F9/6558 , C08K5/15 , C08K5/1545 , C09K15/08 , C09K15/32 , A23L1/302 , A61K7/00 , A61K7/48
Abstract: PROBLEM TO BE SOLVED: To obtain a new compound useful as a medicine, a cosmetic, a food additive, a biological antioxidant and a stabilizer. SOLUTION: This compound is represented by formula I [R is a 1-12C hydrocarbon, a (substituted)cycloalkyl, a heterocyclic ring, etc.; R is an 8-30C hydrocarbon, a (substituted)alkyl, etc.; R is PO3 H2 or glycosidyl; R , R and R are each H, an alkyl, an aryl, an aralkyl, etc.; R is H, or CO-R (R is H, a 1-20C aliphatic or phenylvinyl)]. The compound represented by formula I is obtained by reacting a 5-halogenomethyl-chroman represented by formula II (X is Br or Cl) with an alkali(ne earth) metallic salt of ascorbic acid or an ascorbic acid derivative represented by formula III. The compound represented by formula I can be used to thereby stabilize an organic substance, especially a food, medicine, a cosmetic or a plastic to injurious actions of oxygen, heat and/or light.
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公开(公告)号:NO327978B1
公开(公告)日:2009-11-02
申请号:NO994565
申请日:1999-09-20
Applicant: BASF AG
Inventor: KAESLER BRUNO , STREICHER HARALD , SAMSON WOLFGANG , MUESCHEN HANS
IPC: A23K3/00 , A01N37/02 , A23B7/10 , A23B9/24 , A23B9/26 , A23B9/28 , A23B9/30 , A23K3/03 , A23L3/3463 , A23L3/3481 , A23L3/3508 , A23L3/358 , C02F1/50
Abstract: The disclosure is directed to a solution of78.0-93.0% by weight propionic acid,0.5-5.0% by weight ammonia,1.0-6.0% by weight propanediol,0.1-10.0% by weight water,where the amounts of individual components add up to 100% by weight, and its use in livestock nutrition.
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公开(公告)号:DE10027875A1
公开(公告)日:2001-12-13
申请号:DE10027875
申请日:2000-06-06
Applicant: BASF AG
Inventor: STREICHER HARALD , JENTZSCH AXEL
IPC: C07D339/04 , A61K8/00 , A61K8/06 , A61K8/14 , A61K8/49 , A61K31/381 , A61K31/385 , A61P11/00 , A61Q1/00 , A61Q1/02 , A61Q1/04 , A61Q1/12 , A61Q1/14 , A61Q5/00 , A61Q5/06 , A61Q5/12 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A61Q19/10 , A61K7/48 , A61K7/06 , A61K9/06
Abstract: A cosmetic/dermatological composition comprises: (1) lipoic acid, its derivative or salt (0.001 - 30 wt.%) having an (R)-enantiomer excess (ee) of at least 40 (preferably 80, especially 98)%; (2) optionally at least one active ingredient; and (3) carrier or a formulation base. An Independent claim is included for a commercial pack containing the composition with instructions for the therapeutic use of (a).
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公开(公告)号:DE19903459A1
公开(公告)日:2000-08-03
申请号:DE19903459
申请日:1999-01-28
Applicant: BASF AG
Inventor: STREICHER HARALD , BURST WOLFRAM , DAEUWEL JUERGEN , KOPPENHOEFER JUERGEN
Abstract: Production of highly pure phytantriol (I) comprises rectification of (I) in a fine vacuum in columns with ordered metal fabric packing and duct distributors with ≥ 500 dripping points/m at an angle of 90 degrees to the layer of fabric just below them. There are 2 or more, 20-100 mm high packing elements with layers of fabric at 90 degrees to one another. Strictly adiabatic rectification with absolute exclusion of air is used. Production of highly pure phytantriol (I) comprises rectification of (I) contaminated with lower and/or higher boiling by-products in a fine vacuum in columns containing metal fabric packing with ordered structure. The liquid is distributed with duct distributors with ≥ 500 dripping points/m . The ducts are at an angle of 90 degrees to the layer of fabric directly below them in the packing. There are 2 or more packing elements with a height of 20-100 mm and layers of fabric at 90 degrees to one another, below the distributor. The process is operated with absolute exclusion of air. Strictly adiabatic rectification is used.
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公开(公告)号:DE59706478D1
公开(公告)日:2002-04-04
申请号:DE59706478
申请日:1997-08-13
Applicant: BASF AG
Inventor: ROSENAU THOMAS , HABICHER WOLF-DIETER , STREICHER HARALD
IPC: A23L33/15 , A61K8/00 , A61K8/49 , A61K8/67 , A23L1/30 , A61K31/35 , A61K31/375 , A61P43/00 , A61Q19/00 , C07D407/12 , C07F9/6558 , C08K5/15 , C08K5/1545 , C09K15/08 , C09K15/32
Abstract: Chromanyl-ascorbic acid derivatives of formula (I) are new. R1 = 1-12C aliphatic hydrocarbyl; or 4-12C cycloalkyl, aryl or heterocyclyl (optionally substituted by one or more alkyl, alkoxy, OH, NH2 or mono- or dialkylamino); R2 = 8-30C (especially 12-24C) hydrocarbyl, 1-6C alkyl (optionally substituted by COOH); or 4-20C cycloalkyl, aryl or heterocyclyl (optionally substituted by one or more alkyl, alkoxy, OH, NH2 or mono- or dialkylamino); R3 = PO3H2 or glycosidyl; R3-R5 = H or 1-20C alkyl, cycloalkyl, aryl, aralkyl, cycloalkylalkyl or COR7 (sic); or R4 + R5 = alkylene optionally substituted by one or more alkyl; R6 = H or COR7; and R7 = H, 1-20C aliphatic hydrocarbyl or phenyl-vinyl. N.B. R3 is defined twice in the main claim, but in dependent claims is defined once with R4 and R5 (see "More Specifically").
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公开(公告)号:AU7055401A
公开(公告)日:2001-12-17
申请号:AU7055401
申请日:2001-06-05
Applicant: BASF AG
Inventor: STREICHER HARALD , JENTZSCH AXEL
IPC: C07D339/04 , A61K8/00 , A61K8/06 , A61K8/14 , A61K8/49 , A61K31/381 , A61K31/385 , A61P11/00 , A61Q1/00 , A61Q1/02 , A61Q1/04 , A61Q1/12 , A61Q1/14 , A61Q5/00 , A61Q5/06 , A61Q5/12 , A61Q15/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A61Q19/10 , A61K7/48 , A61K7/06
Abstract: The present invention relates to the use of lipoic acid, lipoic acid derivatives or salts thereof having an (R)-enantiomer-excess in cosmetic compositions for skin or hair and for the preparation of dermatological compositions for the treatment of skin disorders, to cosmetic and dermatological compositions, and to compositions in the form of commercial packs.
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公开(公告)号:DE19941595A1
公开(公告)日:2001-03-08
申请号:DE19941595
申请日:1999-09-01
Applicant: BASF AG
Inventor: STREICHER HARALD
IPC: C07D307/79 , A61K8/00 , A61K8/02 , A61K8/06 , A61K8/49 , A61K31/343 , A61K31/352 , A61K31/353 , A61P39/06 , A61Q1/00 , A61Q1/04 , A61Q1/06 , A61Q5/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , C07D311/72 , A61K7/00 , A61K7/40
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公开(公告)号:CZ329799A3
公开(公告)日:1999-12-15
申请号:CZ329799
申请日:1998-03-17
Applicant: BASF AG
Inventor: KAESLER BRUNO , MUSCHEN HANS , STREICHER HARALD , SAMSON WOLFGANG
IPC: A01N37/02 , A23B7/10 , A23B9/24 , A23B9/26 , A23B9/28 , A23B9/30 , A23K3/00 , A23K3/03 , A23L3/3463 , A23L3/3481 , A23L3/3508 , A23L3/358 , C02F1/50
Abstract: The disclosure is directed to a solution of78.0-93.0% by weight propionic acid,0.5-5.0% by weight ammonia,1.0-6.0% by weight propanediol,0.1-10.0% by weight water,where the amounts of individual components add up to 100% by weight, and its use in livestock nutrition.
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公开(公告)号:NO994565D0
公开(公告)日:1999-09-20
申请号:NO994565
申请日:1999-09-20
Applicant: BASF AG
Inventor: KAESLER BRUNO , MUESCHEN HANS , STREICHER HARALD , SAMSON WOLFGANG
IPC: A01N37/02 , A23B7/10 , A23B9/24 , A23B9/26 , A23B9/28 , A23B9/30 , A23K3/00 , A23K3/03 , A23L3/3463 , A23L3/3481 , A23L3/3508 , A23L3/358 , C02F1/50
Abstract: The disclosure is directed to a solution of78.0-93.0% by weight propionic acid,0.5-5.0% by weight ammonia,1.0-6.0% by weight propanediol,0.1-10.0% by weight water,where the amounts of individual components add up to 100% by weight, and its use in livestock nutrition.
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公开(公告)号:AU7033198A
公开(公告)日:1998-10-20
申请号:AU7033198
申请日:1998-03-17
Applicant: BASF AG
Inventor: KAESLER BRUNO , MUSCHEN HANS , STREICHER HARALD , SAMSON WOLFGANG
IPC: A01N37/02 , A23B7/10 , A23B9/24 , A23B9/26 , A23B9/28 , A23B9/30 , A23K3/00 , A23K3/03 , A23L3/3463 , A23L3/3481 , A23L3/3508 , A23L3/358 , C02F1/50
Abstract: The disclosure is directed to a solution of78.0-93.0% by weight propionic acid,0.5-5.0% by weight ammonia,1.0-6.0% by weight propanediol,0.1-10.0% by weight water,where the amounts of individual components add up to 100% by weight, and its use in livestock nutrition.
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