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公开(公告)号：DE59010205D1
公开(公告)日：1996-04-18
申请号：DE59010205
申请日：1990-11-22
Applicant: BASF AG
Inventor： KURFUERST MANFRED , RUEBSAMEN KLAUS , SCHMIED BERNHARD , KOERWER WOLFGANG , SCHWEDEN JUERGEN , HOEFFKEN HANS
IPC: A61K38/55 , A61K38/00 , A61K38/58 , A61K47/48 , A61P7/02 , C07K14/815 , C07K17/08 , C12N15/09 , C12P21/02 , C12R1/19
Abstract: PCT No. PCT/EP90/01998 Sec. 371 Date May 29, 1992 Sec. 102(e) Date May 29, 1992 PCT Filed Nov. 22, 1990 PCT Pub. No. WO91/08229 PCT Pub. Date Jun. 13, 1991Hirudin/polyalkylene glycol derivatives of the formula[A-(CH2)n-[O-(CH2)nlm-B-]p Hir [sic]I and hirudin muteins and the preparation thereof are described. The compounds are suitable for controlling diseases.
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公开(公告)号：AU611113B2
公开(公告)日：1991-06-06
申请号：AU8240387
申请日：1987-12-10
Applicant: BASF AG
Inventor： SEITZ WERNER , UNGER LILIANE , RASCHACK MANFRED , BALDINGER VERENA , RUEBSAMEN KLAUS , GRIES JOSEF
IPC: A61K31/275 , A61K31/335 , A61K31/357 , A61K31/36 , A61P1/04 , A61P3/00 , A61P9/00 , A61P11/00 , A61P43/00 , C07C67/00 , C07C253/00 , C07C253/30 , C07C255/32 , C07C255/33 , C07C255/35 , C07C255/37 , C07C255/42 , C07C255/53 , C07C255/58 , C07D317/50 , C07D317/60 , C07D319/08 , C07D319/18 , C07D321/00 , C07C121/80 , C07C121/78
Abstract: Basic-substituted phenylacetonitriles of the formula I … … in which… R to R and n have the meaning given in the description, are suitable for combating diseases.
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公开(公告)号：CA2067224A1
公开(公告)日：1991-06-02
申请号：CA2067224
申请日：1990-11-22
Applicant: BASF AG
Inventor： KURFUERST MANFRED , RUEBSAMEN KLAUS , SCHMIED BERNHARD , KOERWER WOLFGANG , SCHWEDEN JUERGEN , HOEFFKEN HANS W
IPC: A61K38/55 , A61K38/00 , A61K38/58 , A61K47/48 , A61P7/02 , C07K14/815 , C07K17/08 , C12N15/09 , C12P21/02 , C12R1/19 , C07K17/06
Abstract: Hirudin/polyalkylene glycol derivatives of the formula (A-(CH2)n-[O-(CH2)n]m-B-]p Hir [sic] I and hirudin muteins and the preparation thereof are described. The compounds are suitable for controlling diseases.
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公开(公告)号：FI81347B
公开(公告)日：1990-06-29
申请号：FI852730
申请日：1985-07-10
Applicant: BASF AG
Inventor： GEISS KARL-HEINZ , SCHMIED BERNHARD , RASCHACK MANFRED , LEHMANN HANS-DIETER , GRIES JOSEF , RUEBSAMEN KLAUS
IPC: A61K31/50 , A61K31/55 , A61P1/04 , A61P7/02 , A61P9/04 , A61P9/12 , C07D237/00 , C07D403/04 , C07D403/10
Abstract: Novel pyrrol-1-ylphenyldihydropyridazinones of the formula I their preparation and their use in the treatment of disorders.
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公开(公告)号：FI852730L
公开(公告)日：1986-01-13
申请号：FI852730
申请日：1985-07-10
Applicant: BASF AG
Inventor： GEISS KARL-HEINZ , SCHMIED BERNHARD , RASCHACK MANFRED , LEHMANN HANS-DIETER , GRIES JOSEF , RUEBSAMEN KLAUS
IPC: A61K31/50 , A61K31/55 , A61P1/04 , A61P7/02 , A61P9/04 , A61P9/12 , C07D237/00 , C07D403/04 , C07D403/10 , C07D
Abstract: Novel pyrrol-1-ylphenyldihydropyridazinones of the formula I their preparation and their use in the treatment of disorders.
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Patent Agency Ranking
公开(公告)号：BG62068B2
公开(公告)日：1999-01-29
申请号：BG9860494
申请日：1994-02-28
Applicant: BASF AG
Inventor： KURFUERST MANFRED , RUEBSAMEN KLAUS , SCHMIED BERNHARD , KOERWER WOLFGANG , SCHWEDEN JUERGEN , HOEFFKEN HANS W
IPC: A61K38/55 , A61K38/00 , A61K38/58 , A61K47/48 , A61P7/02 , C07K14/815 , C07K17/08 , C12N15/09 , C12P21/02 , C12R1/19 , C08G65/32
Abstract: The invention relates to new hirudinmuteins and theirpolyalkylenglycol conjugates with the formula[Z-(CH2)n-[O-CH2)n]m-W-]p Hirand to a method for their preparation. The compounds are suitablefor the prevention and treatment of carbiovascular diseases.16 claims
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公开(公告)号：ES2084149T3
公开(公告)日：1996-05-01
申请号：ES91900751
申请日：1990-11-22
Applicant: BASF AG
Inventor： KURFUERST MANFRED , RUEBSAMEN KLAUS , SCHMIED BERNHARD , KOERWER WOLFGANG , SCHWEDEN JURGEN , HOEFFKEN HANS WOLFGANG
IPC: A61K38/55 , A61K38/00 , A61K38/58 , A61K47/48 , A61P7/02 , C07K14/815 , C07K17/08 , C12N15/09 , C12P21/02 , C12R1/19
Abstract: PCT No. PCT/EP90/01998 Sec. 371 Date May 29, 1992 Sec. 102(e) Date May 29, 1992 PCT Filed Nov. 22, 1990 PCT Pub. No. WO91/08229 PCT Pub. Date Jun. 13, 1991Hirudin/polyalkylene glycol derivatives of the formula[A-(CH2)n-[O-(CH2)nlm-B-]p Hir [sic]I and hirudin muteins and the preparation thereof are described. The compounds are suitable for controlling diseases.
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18.发明专利
公开(公告)号：FI81347C
公开(公告)日：1990-10-10
申请号：FI852730
申请日：1985-07-10
Applicant: BASF AG
Inventor： GEISS KARL-HEINZ , SCHMIED BERNHARD , RASCHACK MANFRED , LEHMANN HANS-DIETER , GRIES JOSEF , RUEBSAMEN KLAUS
IPC: A61K31/50 , A61K31/55 , A61P1/04 , A61P7/02 , A61P9/04 , A61P9/12 , C07D237/00 , C07D403/04 , C07D403/10
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公开(公告)号：ES2015273B3
公开(公告)日：1990-08-16
申请号：ES87100041
申请日：1987-01-03
Applicant: BASF AG
Inventor： GEISS KARL-HEINZ , SCHMIED BERNHARD , KROPP RUDOLF , BALDINGER VERENA , GRIES JOSEF , LEHMANN HANS DIETER , RUEBSAMEN KLAUS
IPC: C07D237/00 , A61K31/50 , A61P1/04 , A61P7/02 , A61P9/04 , A61P9/12 , C07D403/04 , C07D403/10
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公开(公告)号：NO162557C
公开(公告)日：1990-01-17
申请号：NO852793
申请日：1985-07-11
Applicant: BASF AG
Inventor： GEISS KARL-HEINZ , SCHMIED BERNHARD , RASCHACK MANFRED , LEHMANN HANS-DIETER , GRIES JOSEF , RUEBSAMEN KLAUS
IPC: A61K31/50 , A61K31/55 , A61P1/04 , A61P7/02 , A61P9/04 , A61P9/12 , C07D237/00 , C07D403/04 , C07D403/10
Abstract: Novel pyrrol-1-ylphenyldihydropyridazinones of the formula I their preparation and their use in the treatment of disorders.
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