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    13.
    发明专利
    未知

    公开(公告)号：DE10115840A1

    公开(公告)日：2002-10-10

    申请号：DE10115840

    申请日：2001-03-30

    Applicant: BASF AG

    Inventor： STREICHER HARALD

    IPC: A61K31/07 ,  C07C275/00 ,  A61K7/48 ,  A61K7/06 ,  A61K7/42

    Abstract: The invention relates to the use of retinyl carbonates of formula (I), wherein R represents an optionally substituted C1-C12 alkyl, C6-C12 aryl, C7-C13 aralkyl or a group of formula (II), for the cosmetic treatment of the skin or hair and for the dermatological treatment of skin diseases. The invention also relates to corresponding cosmetic and dermatological agents.

    Cosmetic preparations containing new or known 4-oxoretinol compounds, useful for prophylaxis of aging of the skin or hair
    18.
    发明专利
    Cosmetic preparations containing new or known 4-oxoretinol compounds, useful for prophylaxis of aging of the skin or hair 未知

    公开(公告)号：DE10010814A1

    公开(公告)日：2001-09-13

    申请号：DE10010814

    申请日：2000-03-08

    Applicant: BASF AG

    Inventor： JENTZSCH AXEL ,  ERNST HANSGEORG ,  STREICHER HARALD ,  KLEIN DANIELA

    IPC: A61K8/35 ,  A61K8/67 ,  A61Q5/00 ,  A61Q17/00 ,  A61Q19/08 ,  C07C403/16 ,  C07D311/58 ,  C07D311/72 ,  A61K7/00 ,  A61K7/06 ,  A61K7/48

    Abstract: The use of 4-oxo-retinol compounds (I) (including the free alcohol and ether, ester or carbonate derivatives) in cosmetic preparations is new. Some of (I) are new compounds. The use of 4-oxo-retinol compounds (I) in cosmetic preparations is new. [Image] R : H, 1-12C alkyl, 1-20C acyl, 1-12C alkoxycarbonyl, amino acid residue or tocopherol derivative residue of formula (i). [Image] Independent claims are included for: (1) cosmetic preparations for protecting the human epidermis or hair, comprising an effective amount of (I) in a carrier; and (2) (I; R = R') as new compounds. R' : 1-12C alkoxycarbonyl, amino acid residue or group (i). - ACTIVITY : Dermatological; antiseborrheic; antiinflammatory; antiallergic; immunosuppressive. - MECHANISM OF ACTION : Radical scavenger; antioxidant; regulation of collagen, hyaluronic acid or elastin synthesis; stimulation of DNA synthesis; regulation of transcription and translation of matrix-degrading enzymes (especially matrix metalloproteases); promotion of cellular renewal and regeneration of the skin; stimulation of intrinsic DNA, lipid and/or protein protection and repair mechanisms in the skin.

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