公开(公告)号：WO2014098818A1

公开(公告)日：2014-06-26

申请号：PCT/US2012/070498

申请日：2012-12-19

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： PAN, Long ,  YUAN, Shaotang ,  MATTAI, Jairajh ,  MASTERS, James G.

IPC: C07F3/06 ,  A61Q15/00

CPC classification number: A61K8/27 ,  A61K8/44 ,  A61K2800/58 ,  A61K2800/591 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/10 ,  C07B2200/13 ,  C07F3/06

Abstract: The invention provides a zinc-lysine complex having the formula [Zn(C 6 H 14 N 2 O 2 ) 2 Cl] + Cl ¯ having antibacterial and antiperspirant properties, together with personal care compositions comprising the complex, and methods of making and using these complexes and compositions. The application discloses a general reaction for formation of such complexes by mixing a Zn source with Lysine in 1:2 ratio: ZnO + 2 (Lysine 'HCI) - > [Zn(Lysine) 2 CI ] + CI - ⋅( H 2 O) 2

Abstract translation: 本发明提供具有抗菌和止汗性质的具有式[Zn（C 6 H 14 N 2 O 2）2 Cl] + Cl的锌 - 赖氨酸复合物，以及包含该复合物的个人护理组合物，以及制备和使用这些复合物和组合物的方法。 本申请公开了通过将Zn源与1：2比例的赖氨酸混合形成这种络合物的一般反应：ZnO + 2（赖氨酸HCl）→[Zn（赖氨酸）2 Cl] + Cl-（H 2 O）2

公开(公告)号：WO2012148481A1

公开(公告)日：2012-11-01

申请号：PCT/US2011/066018

申请日：2011-12-20

Applicant: COLGATE-PALMOLIVE COMPANY ,  VAUGHN, John ,  PAPPAS, Iraklis ,  PAN, Long

Inventor： VAUGHN, John ,  PAPPAS, Iraklis ,  PAN, Long

IPC: C01F7/00 ,  C01F7/56 ,  C01G25/00

CPC classification number: C01F7/026 ,  A61K8/26 ,  A61K8/28 ,  A61K8/44 ,  A61K2800/58 ,  A61Q15/00 ,  C01F7/002 ,  C01F7/56 ,  C01P2002/86 ,  C01P2002/87

Abstract: A composition comprising a polyhydroxyoxoaluminum cation detectable at 76 ppm by 27 Al NMR that is present in a relative abundance on a 27 Al NMR spectrograph that is greater than any other polyhydroxyoxoaluminum cation detectable by 27 Al NMR. Also, disclosed are methods of making the composition.

Abstract translation: 包含通过27Al NMR在76ppm下可检测的聚羟基氧代铝阳离子的组合物，其在27Al NMR光谱仪上的相对丰度存在，其大于可通过27Al NMR检测的任何其它聚羟基氧代铝阳离子。 此外，公开了制备组合物的方法。

公开(公告)号：WO2011079001A2

公开(公告)日：2011-06-30

申请号：PCT/US2010/060634

申请日：2010-12-16

Applicant: COLGATE-PALMOLIVE COMPANY ,  PAN, Long ,  WU, Donghui ,  KILPATRICK-LIVERMAN, LaTonya ,  EIBLING, Matthew J. ,  FITZGERALD, Michael ,  PAPPAS, Iraklis

Inventor： PAN, Long ,  WU, Donghui ,  KILPATRICK-LIVERMAN, LaTonya ,  EIBLING, Matthew J. ,  FITZGERALD, Michael ,  PAPPAS, Iraklis

IPC: A61Q15/00

CPC classification number: A61K8/416 ,  A61K8/26 ,  A61K8/42 ,  A61K8/44 ,  A61K2800/31 ,  A61K2800/58 ,  A61Q15/00

Abstract: An anhydrous liquid antiperspirant/deodorant composition comprising a carrier comprising a cation and/or zwitterion and a hydrogen bond donor, wherein an amount of carrier is greater than an amount of any other material in the composition, and an antiperspirant active. This represents a new delivery form for antiperspirant actives and/or deodorant actives.

Abstract translation: 一种无水液体止汗剂/除臭剂组合物，其包含载体，其包含阳离子和/或两性离子和氢键供体，其中载体的量大于组合物中任何其它材料的量和止汗活性剂。 这代表了止汗活性物质和/或除臭活性物质的新的交付形式。

公开(公告)号：WO2021263151A1

公开(公告)日：2021-12-30

申请号：PCT/US2021/039167

申请日：2021-06-25

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： LI, Ningwei ,  SHEN, Hongwei ,  TANG, Saide ,  WON, Betty ,  DUBOVOY, Viktor ,  PAN, Long

IPC: A61Q11/00 ,  A61K8/24 ,  A61K8/43 ,  A61K8/60 ,  A61K8/49 ,  A61K8/46 ,  A61K8/44 ,  A61K2800/28 ,  A61K2800/48 ,  A61K2800/524 ,  A61K2800/5422 ,  A61K2800/5426 ,  A61K2800/5428 ,  A61K2800/74 ,  A61K8/442 ,  A61K8/466 ,  A61K8/4926 ,  A61K8/604

Abstract: This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, in particular, chlorhexidine and polyphosphate salts, by formulating the composition with a surfactant.

公开(公告)号：WO2020214311A1

公开(公告)日：2020-10-22

申请号：PCT/US2020/023068

申请日：2020-03-17

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： HAO, Zhigang ,  THOMSON, Paul ,  PAN, Long ,  BRINZARI, Tatiana ,  XU, Guofeng ,  LEITE, Sergio ,  WANG, Yu

IPC: A61K8/21 ,  A61K8/24 ,  A61Q11/00

Abstract: Disclosed herein are improved methods for the synthesis of stannous pyrophosphate, as well as improved methods for the manufacture of oral care compositions comprising stannous pyrophosphate.

公开(公告)号：WO2020086298A1

公开(公告)日：2020-04-30

申请号：PCT/US2019/055755

申请日：2019-10-11

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： BRINZARI, Tatiana ,  STRANICK, Michael ,  CHENG, Chi-Yuan ,  HAO, Zhigang ,  PAPPAS, Iraklis ,  MARRON, Greggory ,  DUBOVOY, Viktor ,  PAN, Long

IPC: A61K8/19 ,  A61K8/27 ,  A61K8/44 ,  A61K8/46 ,  A61Q11/00

Abstract: Described herein are zinc-amino acid-lauryl sulfate complexes and oral care compositions comprising the same; and methods of making and using the same are also described.

公开(公告)号：WO2019125826A1

公开(公告)日：2019-06-27

申请号：PCT/US2018/064964

申请日：2018-12-11

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： PAN, Long ,  WU, Donghui ,  SUBRAMANYAM, Ravi ,  SHEN, Hongwei ,  CHENG, Chi-Yuan ,  BRINZARI, Tatiana

IPC: A61Q11/00 ,  C07C269/04 ,  C07C271/06 ,  A61P31/04

CPC classification number: A61K8/44 ,  A61K8/19 ,  A61K8/21 ,  A61K8/442 ,  A61K8/445 ,  A61K8/447 ,  A61K8/492 ,  A61K8/4946 ,  A61K31/198 ,  A61K31/4172 ,  A61K33/16 ,  A61K2800/58 ,  A61Q11/00 ,  C07C269/04 ,  C07C271/06 ,  C07C279/14

Abstract: Disclosed herein are amino acid carbamate complexes, methods of synthesis thereof, oral care compositions comprising the same, and methods of making and using thereof.

公开(公告)号：WO2019118452A1

公开(公告)日：2019-06-20

申请号：PCT/US2018/064940

申请日：2018-12-11

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： HAO, Zhigang ,  CHENG, Chi-Yuan ,  PAN, Long ,  SUBRAMANYAM, Ravi

IPC: C07F9/655 ,  A61Q11/00 ,  A61K8/19

CPC classification number: C07F9/65515 ,  A61K8/19 ,  A61K8/21 ,  A61K8/27 ,  A61K8/365 ,  A61K8/44 ,  A61K8/55 ,  A61K8/676 ,  A61K2800/58 ,  A61Q11/00

Abstract: Disclosed herein are stannous-ascorbyl phosphate and stannic-asorbyl phosphate complexes, oral care compositions stannous-ascorbyl phosphate and stannic-asorbyl phosphate complexes, and methods of making and using the same.

公开(公告)号：WO2019118432A1

公开(公告)日：2019-06-20

申请号：PCT/US2018/064908

申请日：2018-12-11

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： DUBOVOY, Viktor ,  PETROU, Irene ,  PAN, Long

IPC: C01G25/00 ,  A61K8/00 ,  C01F5/10 ,  C02F5/10

CPC classification number: C01G25/04 ,  A61K8/21 ,  A61K8/28 ,  A61K8/44 ,  A61K2800/413 ,  A61K2800/805 ,  A61Q11/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01F5/10 ,  C01G25/00 ,  C01P2002/87 ,  C01P2004/64

Abstract: Described herein are zirconium oxychloride clusters comprising zirconium oxychloride and a basic amino acid. Oral care compositions comprising the same; and methods of making and using the same are also described.

公开(公告)号：WO2019118302A1

公开(公告)日：2019-06-20

申请号：PCT/US2018/064576

申请日：2018-12-07

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： HAO, Zhigang ,  ZHANG, Dennis ,  WU, Donghui ,  SUBRAMANYAM, Ravi ,  CHENG, Chi-Yuan ,  PAN, Long ,  JARACZ, Stanislav

IPC: A61K8/24 ,  A61K8/27 ,  A61K8/44 ,  A61Q11/00 ,  A61Q15/00

CPC classification number: A61K8/58 ,  A61K8/24 ,  A61K8/27 ,  A61K8/44 ,  A61K2800/58 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/005

Abstract: Disclosed herein are zinc-amino acid-tripolyphosphate complexes, oral care and personal care compositions comprising zinc-amino acid-tripolyphosphate complexes, and methods of making and using the same.