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公开(公告)号:AU5761690A
公开(公告)日:1991-01-03
申请号:AU5761690
申请日:1990-06-19
Applicant: HOECHST AG
Inventor: HEDTMANN UDO , FEHLHABER HANS-WOLFRAM , SUKATSCH DIETER-ANDREAS , KRAEMER HANS PETER , HOFFMANN DIETER
IPC: A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P35/00 , C07H15/252 , C12P19/56 , C12R1/00 , C07H17/04
Abstract: The present invention relates to anthracycline derivatives of the formula I in which R is the sugar residue Roa or the sugar combination Roa-Rod-Rod and R is the sugar residue Roa, where Roa represents rhodosamine of the formula II and Roa-Rod-Rod represents rhodosamine-rhodinose-rhodinose of the formula III and to the pharmacologically acceptable salts thereof and to a microbiological process for the preparation thereof. The compounds have cytostatic activity and can therefore be used as medicaments.
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公开(公告)号:PT501215E
公开(公告)日:2000-10-31
申请号:PT92102197
申请日:1992-02-10
Applicant: HOECHST AG
Inventor: SEEMANN GERHARD , BOSSLET KLAUS , CZECH JORG , KOLAR CENEK , HOFFMANN DIETER , SEDLACEK HANS-HARALD
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公开(公告)号:DE59209839D1
公开(公告)日:2000-06-29
申请号:DE59209839
申请日:1992-02-10
Applicant: HOECHST AG
Inventor: SEEMANN GERHARD , BOSSLET KLAUS , CZECH JOERG , KOLAR CENEK , HOFFMANN DIETER , SEDLACEK HANS-HARALD
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14.
公开(公告)号:CA2019315A1
公开(公告)日:1990-12-20
申请号:CA2019315
申请日:1990-06-19
Applicant: HOECHST AG
Inventor: HEDTMANN UDO , FEHLHABER HANS-WOLFRAM , SUKATSCH DIETER-ANDREAS , KRAEMER HANS PETER , HOFFMANN DIETER
IPC: A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P35/00 , C07H15/252 , C12P19/56 , C12R1/00 , A61K31/65
Abstract: of the disclosure: Novel anthracycline derivatives, a process for the preparation thereof and the use thereof as a pharmaceutical The present invention relates to anthracycline derivatives of the formula I (I) in which R1 is the sugar residue Roa or the combination of sugars Roa-Rod-Rod and R2 is the sugar residue Roa, Roa being rhodosamine of the formula II (II) and Roa-Rod-Rod being rhodosamine-rhodinose-rhodinose of the formula III (III) and the pharmacologically acceptable salts thereof, and a microbiological process for the preparation thereof. The compounds have cytostatic activity and can therefore be used as pharmaceuticals.
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公开(公告)号:CA1030551A
公开(公告)日:1978-05-02
申请号:CA193886
申请日:1974-03-01
Applicant: HOECHST AG
Inventor: BRECHT HEINZ , HOFFMANN DIETER
IPC: C07C305/10 , A01N25/30 , C07C67/00 , C07C301/00 , C07C303/24 , C07C305/06 , C09G1/00 , C09K23/00 , C11D1/00
Abstract: 1457322 Biocidal compositions containing novel wetting agents HOECHST AG 27 Feb 1974 [2 March 1973] 8809/74 Heading A5E [Also in Divisions B1, CC2 and C3] Novel Wetting agents of formula: in which R f is a straight-chain perflouroalkyl group having from 6 to 10 carbon atoms, n is 1 or 2, p is 2 or 3, m has a value of from 1 to 12, and M is a cation selected from hydrogen, sodium, potassium, ammonium, ammonium substituted by 1 to 3 alkyl groups each having from 1 to 4 carbon atoms, and ammonium substituted by 1 to 3 hydroxyalkyl groups each having 2 to 4 carbon atoms, are used in biocide spray powders containing Lindan, DDT, Endosulfan, and N-trichloromethyl-thiophthalimide.
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公开(公告)号:AU4290672A
公开(公告)日:1973-12-06
申请号:AU4290672
申请日:1972-05-31
Applicant: HOECHST AG
Inventor: STACH HANS , HOFFMANN DIETER , BRECHT HEINZ
IPC: C09K23/22 , C11D1/00 , C07C103/44 , B01F3/08
Abstract: 1391618 Perfluorocarboxylic acid derivatives HOECHST AG 2 June 1972 [2 June 1971] 25903/72 Heading C2C [Also in Division B1] Novel perfluorocarboxylic acid derivatives of formula RfCO.NH.(CH 2 ) 3 .Y where Rf is an unbranched C 6 -C 10 perfluoroalkyl group and Y is a group of formulae -N[(CH 2 CH 2 O) n H] 2 , [(CH 2 ) q COO - ] or where R is C 1 -C 4 alkyl, X- is a halogen, sulphate or methosulphate anion, n is 1-5 and q is 1 or 2, are prepared by reacting an alkyl perfluoroalkanoate of formula RfCOOR where R is alkyl, with N,N-di-#-hydroxyethylpropylenediamine followed by optional etherification, esterification, or quaternization. The novel derivatives are used as melting and dispersing agents and as emulsifiers.
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17.
公开(公告)号:CA904336A
公开(公告)日:1972-07-04
申请号:CA904336D
Applicant: HOECHST AG
Inventor: SCHUIERER ERICH , HOFFMANN DIETER
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公开(公告)号:DE69425356T2
公开(公告)日:2002-04-18
申请号:DE69425356
申请日:1994-09-09
Applicant: HOECHST AG , HOECHST HOUDE S A LAB
Inventor: BOSSLET KLAUS , CZECH JOERG , HOFFMANN DIETER , TILLEQUIN FRANCOIS , FLORENT JEAN-CLAUDE , AZOULAY MICHEL , MONNERET CLAUDE , JACQUESY JEAN-CLAUDE , GESSON JEAN-PIERRE , KOCH MICHEL
IPC: C07H15/244 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61K47/48 , A61P43/00
Abstract: Substrate-spacer-prodrug compounds (pro-prodrugs) suited for site specific delivery of drugs, a process of preparing them and their use are described.
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公开(公告)号:ES2149159T3
公开(公告)日:2000-11-01
申请号:ES92102197
申请日:1992-02-10
Applicant: HOECHST AG
Inventor: SEEMANN GERHARD , BOSSLET KLAUS , CZECH JORG , KOLAR CENEK , HOFFMANN DIETER , SEDLACEK HANS-HARALD
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公开(公告)号:DK0501215T3
公开(公告)日:2000-09-18
申请号:DK92102197
申请日:1992-02-10
Applicant: HOECHST AG
Inventor: SEEMANN GERHARD , BOSSLET KLAUS , CZECH JOERG , KOLAR CENEK , HOFFMANN DIETER , SEDLACEK HANS-HARALD
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