-
公开(公告)号：BR112013002182A2
公开(公告)日：2016-05-31
申请号：BR112013002182
申请日：2011-07-28
Applicant: ONCOTHERAPY SCIENCE INC
Inventor： AHMED FERYAN , DECORNEZ HELENE , WALKER JOEL R , HUNTLEY RAYMOND , HISADA SHOJI , MATSUO YO , NAKAMURA YUSUKE
Abstract: derivados de quinolina e inibidores de melk contendo os mesmos. a presente invenção refere-se a um composto representado por fórmula (i).
-
公开(公告)号：SG11201403335WA
公开(公告)日：2014-09-26
申请号：SG11201403335W
申请日：2012-12-21
Applicant: ONCOTHERAPY SCIENCE INC
Inventor： MATSUO YO , HISADA SHOJI , NAKAMURA YUSUKE , AHMED FERYAN , WALKER JOEL R , HUNTLEY RAYMOND
IPC: A61K31/4745 , C07D471/04
-
公开(公告)号：AU2011282588A1
公开(公告)日：2013-03-21
申请号：AU2011282588
申请日：2011-07-28
Applicant: ONCOTHERAPY SCIENCE INC
Inventor： MATSUO YO , HISADA SHOJI , NAKAMURA YUSUKE , AHMED FERYAN , HUNTLEY RAYMOND , WALKER JOEL R , DECORNEZ HELENE
Abstract: The present invention directs a compound represented by formula (I).
-
公开(公告)号：SG184376A1
公开(公告)日：2012-11-29
申请号：SG2012072807
申请日：2011-03-29
Applicant: ONCOTHERAPY SCIENCE INC
Inventor： NAKAMURA YUSUKE , MATSUO YO , HISADA SHOJI , AHMED FERYAN , HUNTLEY RAYMOND , SAJJADI-HASHEMI ZOHREH , JENKINS DAVID M , KARGBO ROBERT B , CUI WENGE , GAUUAN POLIVINA JOLICIA F , WALKER JOEL R , DECORNEZ HELENE , GURRAM MAHENDER
Abstract: Trycyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
-
公开(公告)号：CO6361855A2
公开(公告)日：2012-01-20
申请号：CO11060496
申请日：2011-05-17
Applicant: ONCOTHERAPY SCIENCE INC
Inventor： MATSUO YO , OHSAWA RYUJI , HISADA SHOJI , LI YINGFU , WALKER JOEL R , AHMED FERYAN
IPC: A01N43/80
Abstract: La presente invención se refiere a derivados de 7-hidroxi-benzoimidazol-4-il-metanona de fórmula (I), y una sal farmacéuticamente aceptable, hidrato, solvato, o isómero de los mismos:para inhibir la actividad de PBK, un método para la preparación de los mismos, y una composición farmacéutica que contiene los mismos como ingrediente activo.
-
Patent Agency Ranking16.发明专利
公开(公告)号：CA2732280A1
公开(公告)日：2010-02-04
申请号：CA2732280
申请日：2009-07-30
Applicant: ONCOTHERAPY SCIENCE INC
Inventor： OHTANI MITSUAKI , MATSUO YO , LI YINGFU , WALKER JOEL R , JENKINS DAVID M , AHMED FERYAN , OHSAWA RYUJI , HISADA SHOJI
IPC: A01N43/30
Abstract: Benzoimidazole Derivatives are provided. The compounds of the present invention are useful for Glycogen Synthase Kinase-3 Beta Inhibitors.
-
公开(公告)号：BR112012023836B1
公开(公告)日：2022-02-01
申请号：BR112012023836
申请日：2011-03-29
Applicant: ONCOTHERAPY SCIENCE INC
Inventor： DAVID M JENKINS , AHMED FERYAN , DECORNEZ HELENE , JOEL R WALKER , GURRAM MAHENDER , POLIVINA JOLICIA F GAUUAN , HUNTLEY RAYMOND , ROBERT B KARGBO , HISADA SHOJI , CUI WENGE , MATSUO YO , NAKAMURA YUSUKE , SAJJADI-HASHEMI ZOHREH
IPC: C07D213/64 , A61P35/00 , C07D221/06 , C07D221/16 , C07D401/04 , C07D401/10 , C07D487/04 , C07D495/04 , C07D513/04 , C07D519/00
Abstract: compostos tricíclicos, composição farmacêutica compreendendo os referidos compostos, inibidor de pbk contendo os mesmos e uso dos referidos compostos. a presente invenção refere-se a compostos tricíclicos que são fornecidos. estes compostos são inibidores de pbk, e são úteis para o tratamento de doenças relacionadas com pbk, incluindo câncer.
-
公开(公告)号：MX366983B
公开(公告)日：2019-08-01
申请号：MX2014008780
申请日：2012-12-21
Applicant: ONCOTHERAPY SCIENCE INC
Inventor： NAKAMURA YUSUKE , WALKER JOEL R , MATSUO YO , HISADA SHOJI , AHMED FERYAN , HUNTLEY RAYMOND
IPC: A61K31/4375 , A61K31/4745 , A61K31/496 , A61K31/506 , A61K31/5377 , A61P35/00 , C07D471/04
Abstract: La presente invención está dirigida a un compuesto representado por la fórmula (I), que comprende un derivado de 1,5-naftiridina; en una modalidad, el derivado de 1,5-naftiridina de fórmula (I) tiene actividad inhibitoria contra la cinasa de cierre de leucina embrionaria materna (MELK); la presente invención también incluye un método para preparar el derivado de 1,5-naftiridina de fórmula (I); la presente invención también incluye una composición farmacéutica que contiene el derivado de 1,5-naftiridina de fórmula (I) como ingrediente activo.
-
公开(公告)号：CA2806332C
公开(公告)日：2017-11-14
申请号：CA2806332
申请日：2011-07-28
Applicant: ONCOTHERAPY SCIENCE INC
Inventor： MATSUO YO , HISADA SHOJI , NAKAMURA YUSUKE , AHMED FERYAN , HUNTLEY RAYMOND , WALKER JOEL R , DECORNEZ HELENE
IPC: C07D215/46 , A61K31/47 , A61K31/496 , A61K31/506 , A61K31/5377 , A61P35/00 , C07D401/00 , C07D409/00
Abstract: The present disclosure relates to a quinoline derivative of formula I: (see formula I) The derivatives are useful for inhibiting MELK activity. There is also provided a method for the preparation the derivatives, the use of same for the treatment of diseases that involve overexpression of MELK and a pharmaceutical composition containing the derivatives.
-
公开(公告)号：CA2792941C
公开(公告)日：2017-09-12
申请号：CA2792941
申请日：2011-03-29
Applicant: ONCOTHERAPY SCIENCE INC
Inventor： NAKAMURA YUSUKE , MATSUO YO , HISADA SHOJI , AHMED FERYAN , HUNTLEY RAYMOND , SAJJADI-HASHEMI ZOHREH , JENKINS DAVID M , KARGBO ROBERT B , CUI WENGE , GAUUAN POLIVINA JOLICIA F , WALKER JOEL R , DECORNEZ HELENE , GURRAM MAHENDER
IPC: C07D495/04 , A61K31/4365 , A61K31/444 , A61P35/00
Abstract: Trycyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
-
-
-
-
-
-
-
-
-
Search Results
46
records
(took 0.019 seconds)
