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11.ALTERNATE LABELING STRATEGIES FOR SINGLE MOLECULE SEQUENCING 审中-公开
Title translation: 用于单分子序列的备选标签策略公开(公告)号:WO2009073201A2
公开(公告)日:2009-06-11
申请号:PCT/US2008013363
申请日:2008-12-03
Applicant: PACIFIC BIOSCIENCES CALIFORNIA , KORLACH JONAS , ROITMAN DANIEL , EID JOHN , OTTO GEOFF , HARDENBOL PAUL , FLUSBERG BENJAMIN
Inventor: KORLACH JONAS , ROITMAN DANIEL , EID JOHN , OTTO GEOFF , HARDENBOL PAUL , FLUSBERG BENJAMIN
IPC: G01N33/573 , G01N33/53
CPC classification number: G01N33/54373 , C12Q1/6874 , G01N33/542 , G01N33/54313 , G01N33/573 , G01N33/58 , G01N33/585 , C12Q2565/607 , C12Q2565/531 , C12Q2563/143 , C12Q2563/137
Abstract: Systems and methods of enhancing fluorescent labeling strategies as well as systems and methods of using non-fluorescent and/or non-optic labeling strategies, e.g., as with single molecule sequencing using ZMWs, are described.
Abstract translation: 描述了增强荧光标记策略的系统和方法以及使用非荧光和/或非光学标记策略的系统和方法,例如与使用ZMW的单分子测序一样。
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公开(公告)号:WO2007064905A2
公开(公告)日:2007-06-07
申请号:PCT/US2006046025
申请日:2006-12-01
Applicant: PACIFIC BIOSCIENCES CALIFORNIA , EID JOHN , MURPHY DEVON , OTTO GEOFFREY , TURNER STEPHEN
Inventor: EID JOHN , MURPHY DEVON , OTTO GEOFFREY , TURNER STEPHEN
CPC classification number: A61K38/446 , A61K38/063 , A61K38/443 , G01N33/582
Abstract: Compositions, devices, systems and methods for reducing and/or preventing photodamage of one or more reactants in illuminated analytical reactions by one or more of incorporating photodamage mitigating agents within the reaction mixture and/or interrogating different observation regions of the reaction mixture for a period that is less than a photodamage threshold period.
Abstract translation: 用于通过一种或多种在反应混合物内掺入光损伤缓和剂和/或询问反应混合物的不同观察区域一段时间来减少和/或防止一种或多种反应物在照明分析反应中的光损伤的组合物,装置,系统和方法 这小于光损伤阈值期。
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公开(公告)号:CA2720247A1
公开(公告)日:2009-12-03
申请号:CA2720247
申请日:2009-03-30
Applicant: PACIFIC BIOSCIENCES CALIFORNIA
Inventor: EID JOHN , TURNER STEPHEN , DALAL RAVI , FLUSBERG BENJAMIN , KORLACH JONAS , LIN STEVEN , FEHR ADRIAN , CHRISTIANS FRED , EMIG ROBIN
Abstract: Methods, compositions and arrays for non-random loading of single analyte molecules into array structures are provided.
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公开(公告)号:AU2009251881A1
公开(公告)日:2009-12-03
申请号:AU2009251881
申请日:2009-03-30
Applicant: PACIFIC BIOSCIENCES CALIFORNIA
Inventor: CHRISTIANS FRED , KORLACH JONAS , DALAL RAVI , EID JOHN , LIN STEVEN , FEHR ADRIAN , EMIG ROBIN , FLUSBERG BENJAMIN , TURNER STEPHEN
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公开(公告)号:AU2008331824A1
公开(公告)日:2009-06-11
申请号:AU2008331824
申请日:2008-12-03
Applicant: PACIFIC BIOSCIENCES CALIFORNIA
Inventor: OTTO GEOFF , EID JOHN , KORLACH JONAS , HARDENBOL PAUL , FLUSBERG BENJAMIN , ROITMAN DANIEL
IPC: G01N33/53 , G01N33/535 , G01N33/573
Abstract: Systems and methods of enhancing fluorescent labeling strategies as well as systems and methods of using non-fluorescent and/or non-optic labeling strategies, e.g., as with single molecule sequencing using ZMWs, are described.
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公开(公告)号:AU2006320414A1
公开(公告)日:2007-06-07
申请号:AU2006320414
申请日:2006-12-01
Applicant: PACIFIC BIOSCIENCES CALIFORNIA
Inventor: OTTO GEOFFREY , TURNER STEPHEN , EID JOHN , MURPHY DEVON
Abstract: Compositions, devices, systems and methods for reducing and/or preventing photodamage of one or more reactants in illuminated analytical reactions by one or more of incorporating photodamage mitigating agents within the reaction mixture and/or interrogating different observation regions of the reaction mixture for a period that is less than a photodamage threshold period.
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公开(公告)号:EP1971364A4
公开(公告)日:2010-06-30
申请号:EP06838800
申请日:2006-12-01
Applicant: PACIFIC BIOSCIENCES CALIFORNIA
Inventor: EID JOHN , MURPHY DEVON , OTTO GEOFFREY , TURNER STEPHEN
CPC classification number: A61K38/446 , A61K38/063 , A61K38/443 , G01N33/582
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公开(公告)号:EP2286217A4
公开(公告)日:2011-05-25
申请号:EP09755181
申请日:2009-03-30
Applicant: PACIFIC BIOSCIENCES CALIFORNIA
Inventor: EID JOHN , TURNER STEPHEN , DALAL RAVI , FLUSBERG BENJAMIN , KORLACH JONAS , LIN STEVEN , FEHR ADRIAN , CHRISTIANS FRED , EMIG ROBIN
CPC classification number: B01J19/0046 , B01J2219/00596 , C12N2310/50 , C12N2310/51 , C12Q1/6869 , C12Q2535/122 , C40B40/06 , G01N33/54313 , G01N33/54366
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19.INTERMITTENT DETECTION DURING ANALYTICAL REACTIONS 有权
Title translation: INTERMITTIERENDE DETEKTIONWÄHRENDANALYSEREAKENEN公开(公告)号:EP2331935A4
公开(公告)日:2012-04-18
申请号:EP09816557
申请日:2009-09-16
Applicant: PACIFIC BIOSCIENCES CALIFORNIA
Inventor: MAXHAM KENNETH MARK , SORENSON JON , EID JOHN , MARKS PATRICK , TRAVERS KEVIN , GRAY DONALD , EMIG ROBIN , CHAISSON MARK , FLUSBERG BENJAMIN
CPC classification number: C12Q1/6869 , G01N2021/7786 , Y10T436/143333 , C12Q2525/301 , C12Q2533/101 , C12Q2537/149 , C12Q2565/631 , C12Q2525/307 , C12Q2525/191
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20.ALTERNATE LABELING STRATEGIES FOR SINGLE MOLECULE SEQUENCING 有权
Title translation: 替代MARKIERUNGSVERFAHRENFÜREINZELMOLEKÜLSEQUENZIERUNG公开(公告)号:EP2217928A4
公开(公告)日:2011-02-09
申请号:EP08856043
申请日:2008-12-03
Applicant: PACIFIC BIOSCIENCES CALIFORNIA
Inventor: KORLACH JONAS , ROITMAN DANIEL , EID JOHN , OTTO GEOFF , HARDENBOL PAUL , FLUSBERG BENJAMIN
IPC: G01N33/573 , B01L3/00 , C08G83/00 , C12Q1/68 , G01N33/53 , G01N33/535 , G01N33/542 , G01N33/543 , G01N33/58
CPC classification number: G01N33/54373 , C12Q1/6874 , G01N33/542 , G01N33/54313 , G01N33/573 , G01N33/58 , G01N33/585 , C12Q2565/607 , C12Q2565/531 , C12Q2563/143 , C12Q2563/137
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