-
公开(公告)号：EP2771010A4
公开(公告)日：2015-04-01
申请号：EP12841068
申请日：2012-10-19
Applicant: PHARMACYCLICS INC
Inventor： BUGGY JOSEPH J , ELIAS LAURENCE , FYFE GWEN , HEDRICK ERIC , LOURY DAVID J , MODY TARAK D
IPC: A61K31/52 , A61K31/337 , A61K31/4184 , A61K31/454 , A61K31/475 , A61K31/4965 , A61K31/519 , A61K31/5383 , A61K31/704 , A61K31/7076 , A61P35/00
CPC classification number: A61K31/519 , A61K31/337 , A61K31/4184 , A61K31/454 , A61K31/475 , A61K31/4965 , A61K31/52 , A61K31/5383 , A61K31/704 , A61K31/7076 , A61K45/06 , C12Q1/6886 , G01N33/57484 , A61K2300/00
-
公开(公告)号：EP2575818A4
公开(公告)日：2013-11-06
申请号：EP11790524
申请日：2011-06-03
Applicant: PHARMACYCLICS INC
Inventor： BUGGY JOSEPH J , ELIAS LAURENCE , FYFE GWEN , HEDRICK ERIC , LOURY DAVID J , MODY TARAK D
IPC: A61K31/195 , A61K31/436 , A61K31/454 , A61K31/475 , A61K31/519 , A61K31/573 , A61K31/606 , A61K31/675 , A61K31/69 , A61K31/704 , A61K31/7076 , A61P35/00 , A61P35/02
CPC classification number: A61K31/519 , A61K9/0014 , A61K9/0031 , A61K9/0048 , A61K9/0056 , A61K9/007 , A61K9/06 , A61K31/195 , A61K31/337 , A61K31/4184 , A61K31/436 , A61K31/437 , A61K31/454 , A61K31/4745 , A61K31/475 , A61K31/573 , A61K31/606 , A61K31/664 , A61K31/675 , A61K31/69 , A61K31/7032 , A61K31/704 , A61K31/7076 , A61K39/395 , A61K39/39533 , A61K39/3955 , A61K45/06 , C07D487/04 , A61K2300/00
Abstract: Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.
-
公开(公告)号：EP1576015A4
公开(公告)日：2007-04-04
申请号：EP03796482
申请日：2003-11-24
Applicant: PHARMACYCLICS INC
Inventor： DOUGLAS CARY , FU LEI , MODY TARAK D
IPC: C07D487/22 , C07F3/02 , C07F3/04 , C07F5/00 , C08F20060101 , C08F2/00 , C08F8/42 , C07B47/00
CPC classification number: C07D487/22
Abstract: The present invention provides a process for replacing a metal cation, M1, from a compound of Formula (I).
Abstract translation: 本发明提供了从式（I）化合物中置换金属阳离子M1的方法。
-
公开(公告)号：EP1408955A4
公开(公告)日：2006-09-06
申请号：EP01968223
申请日：2001-08-28
Applicant: PHARMACYCLICS INC
Inventor： MODY TARAK D , GALANTER JOSHUA
IPC: A61K41/00 , C07D487/22 , A61K31/335 , A61P35/00
CPC classification number: C07D487/22 , A61K41/0076
-
15.发明专利
公开(公告)号：UA110853C2
公开(公告)日：2016-02-25
申请号：UAA201402905
申请日：2011-09-13
Applicant: PHARMACYCLICS INC
Inventor： LOURY DAVID J , BUGGY JOSEPH J , MODY TARAK D , VERNER ERIK J , PURRO NORBERT , BALASUBRAMANIAN SRIRAM , KLOOS IOANA , DEPIL STEPHANE
IPC: A61K31/343 , A61K31/16 , A61K31/166 , A61P35/00 , C07D213/68 , C07D307/78 , C07D491/10
Abstract: Винахідстосуєтьсяфармацевтичноїкомпозиції, міститьінгібіторгістодеацетилази (HDAC), бендамустині фармацевтичноприйнятнудопоміжнуречовину, комбінаціїбендамустинуабойогофармацевтичноприйнятногоскладногоефіру, соліабосольватутаінгібітора HDAC ізастосуваннятакоїкомбінаціїдлялікуванняракуу пацієнта, якийцьогопотребує.
-
Patent Agency Ranking
公开(公告)号：AU2010306921B2
公开(公告)日：2015-08-13
申请号：AU2010306921
申请日：2010-10-12
Applicant: PHARMACYCLICS INC
Inventor： CHEN WEI , LOURY DAVID J , MODY TARAK D , VERNER ERIK , SMYTH MARK STEPHEN , LUO WENCHEN
IPC: C07D401/04 , A61K31/519 , A61P19/02 , A61P19/10 , C07D401/14 , C07D487/04
Abstract: Described herein are kinase inhibitor compounds, methods for synthesizing such inhibitors, and methods for using such inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate inhibitor of a protein, including a kinase.
-
17.发明专利
公开(公告)号：AU2011376953A1
公开(公告)日：2014-03-06
申请号：AU2011376953
申请日：2011-09-13
Applicant: PHARMACYCLICS INC , SERVIER SAS LAB
Inventor： LOURY DAVID J , BUGGY JOSEPH J , MODY TARAK D , VERNER ERIK J , PURRO NORBERT , BALASUBRAMANIAN SRIRAM , KLOOS IOANA , DEPIL STEPHANE
IPC: A61K31/343 , A61K31/16 , A61K31/166 , A61P35/00
Abstract: Dosing regimens, methods of treatment, controlled release formulations, and combination therapies that include bendamustine, or a pharmaceutically acceptable salt thereof and an HDAC inhibitor, or a pharmaceutically acceptable salt thereof, are described.
-
公开(公告)号：AU2012283775A8
公开(公告)日：2014-02-20
申请号：AU2012283775
申请日：2012-07-13
Applicant: PHARMACYCLICS INC , WANG LONGCHENG
Inventor： CHEN WEI , LOURY DAVID J , MODY TARAK D , WANG LONGCHENG
IPC: C07D473/32 , A61K31/433 , A61K31/52 , A61P17/00 , A61P29/00 , C07D473/34
Abstract: Described herein are kinase inhibitor compounds, methods for synthesizing such inhibitors, and methods for using such inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate inhibitor of a protein, including a kinase.
-
公开(公告)号：ZA201202552B
公开(公告)日：2013-11-27
申请号：ZA201202552
申请日：2012-04-10
Applicant: PHARMACYCLICS INC
Inventor： LUO WENCHEN , SMYTH MARK STEPHEN , MODY TARAK D , LOURY DAVID J , VERNER ERIK , CHEN WEI
-
公开(公告)号：CA2864736A1
公开(公告)日：2013-08-22
申请号：CA2864736
申请日：2013-02-15
Applicant: PHARMACYCLICS INC
Inventor： BALASUBRAMANIAN SRIRAM , MODY TARAK D
IPC: A61K31/506 , A61K31/517 , A61P35/00
-
-
-
-
-
-
-
-
-
Search Results
114
records
(took 0.022 seconds)
