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公开(公告)号：CA2770714A1
公开(公告)日：2011-03-17
申请号：CA2770714
申请日：2010-08-27
Applicant: STC UNM
Inventor： SMYTH HUGH D C , DONOVAN MARTIN J
Abstract: A method of method of coating powdered medical agent onto a carrier particle for use in a dry powder inhaler may include applying ultrasonic energy to agglomerated powdered medical agent to deaggregate and aerosolize particles of the medical agent into particles having a desired average particle size, and coating at least one carrier particle with a desired amount of the deaggregated and aerosolized particles of the medical agent.
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12.发明公开FORMULATIONS CONTAINING LARGE-SIZE CARRIER PARTICLES FOR DRY POWDER INHALATION AEROSOLS 审中-公开制剂大载体AEROSOLE干粉吸入
公开(公告)号：EP2328556A4
公开(公告)日：2013-11-20
申请号：EP09803599
申请日：2009-07-30
Applicant: STC UNM
Inventor： SMYTH HUGH D C , DONOVAN MARTIN
IPC: A61K9/14
CPC classification number: A61K9/0075 , Y10T428/2982
Abstract: A dry powder inhaler may include a drug chamber configured to contain a formulation including carrier particles and working agent particles, a mouthpiece configured to direct flow of working agent particles to a user, and a retaining member proximal the mouthpiece. The retaining member be sized and arranged to prevent flow of substantially all carrier particles to the user while permitting flow of working agent particles to a user. The inhaler may include a formulation including carrier particles for delivering working agent to the pulmonary system of a patient. The carrier particles may have an average sieve diameter greater than about 500 μm. The carrier particles may be one of polystyrene, PTFE, silicone glass, and silica gel or glass.
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Patent Agency Ranking
公开(公告)号：AU2011224397A1
公开(公告)日：2012-09-06
申请号：AU2011224397
申请日：2011-03-09
Applicant: STC UNM
Inventor： SELVAM PARTHIBAN , SMYTH HUGH D C , DONOVAN MARTIN
Abstract: A device for coating dry powder microparticles onto a surfacemay include a jet mill configured to mill dry powder particles into microparticles having a desired aerodynamic diameter and to deaggregate the microparticles, a feed hopper structured and arranged to feed dry powder particles to the jet mill, a surface configured to receive dry powder microparticles and an exit nozzle associated with the jet mill. The exit nozzle may be arranged to direct deaggregated micronized dry powder particles from the jet mill to the surface to be coated. The device may further include a holder structured and arranged to hold an item, wherein the item includes the surface. In some aspects of the device, the item may be a film.
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公开(公告)号：AU2010319328A1
公开(公告)日：2012-05-31
申请号：AU2010319328
申请日：2010-11-12
Applicant: STC UNM
Inventor： SMYTH HUGH D C , SELVAM PARTHIBAN , TRUMAN CHARLES RANDALL
Abstract: A dry powder inhaler including a housing defining a chamber for receiving a dose of powdered medicament, an inhalation port in fluid communication with the chamber, at least one airflow inlet providing fluid communication between the chamber and an exterior of the housing, and a flutter element in the chamber and associated with a dose of powdered medicament. The flutter element has a tensioned distal end proximate the at least one airflow inlet and a free proximal end opposite to the distal end and downstream of the inlet. The flutter element is configured to vibrate in response to airflow through the chamber and aerosolize the dose of powdered medicament.
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公开(公告)号：CA2789674A1
公开(公告)日：2011-09-15
申请号：CA2789674
申请日：2011-03-09
Applicant: STC UNM
Inventor： SELVAM PARTHIBAN , SMYTH HUGH D C , DONOVAN MARTIN
Abstract: A device for coating dry powder microparticles onto a surfacemay include a jet mill configured to mill dry powder particles into microparticles having a desired aerodynamic diameter and to deaggregate the microparticles, a feed hopper structured and arranged to feed dry powder particles to the jet mill, a surface configured to receive dry powder microparticles and an exit nozzle associated with the jet mill. The exit nozzle may be arranged to direct deaggregated micronized dry powder particles from the jet mill to the surface to be coated. The device may further include a holder structured and arranged to hold an item, wherein the item includes the surface. In some aspects of the device, the item may be a film.
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公开(公告)号：CA2732585A1
公开(公告)日：2010-02-04
申请号：CA2732585
申请日：2009-07-30
Applicant: STC UNM
Inventor： SMYTH HUGH D C , DONOVAN MARTIN
IPC: A61K9/14
Abstract: A dry powder inhaler may include a drug chamber configured to contain a formulation including carrier particles and working agent particles, a mouthpiece configured to direct flow of working agent particles to a user, and a retaining member proximal the mouthpiece. The retaining member be sized and arranged to prevent flow of substantially all carrier particles to the user while permitting flow of working agent particles to a user. The inhaler may include a formulation including carrier particles for delivering working agent to the pulmonary system of a patient. The carrier particles may have an average sieve diameter greater than about 500 µm. The carrier particles may be one of polystyrene, PTFE, silicone glass, and silica gel or glass.
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公开(公告)号：AU2009276498A1
公开(公告)日：2010-02-04
申请号：AU2009276498
申请日：2009-07-30
Applicant: STC UNM
Inventor： SMYTH HUGH D C , DONOVAN MARTIN
IPC: A61K9/14
Abstract: A dry powder inhaler may include a drug chamber configured to contain a formulation including carrier particles and working agent particles, a mouthpiece configured to direct flow of working agent particles to a user, and a retaining member proximal the mouthpiece. The retaining member be sized and arranged to prevent flow of substantially all carrier particles to the user while permitting flow of working agent particles to a user. The inhaler may include a formulation including carrier particles for delivering working agent to the pulmonary system of a patient. The carrier particles may have an average sieve diameter greater than about 500 μm. The carrier particles may be one of polystyrene, PTFE, silicone glass, and silica gel or glass.
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