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    NON-INVASIVE SYSTEM FOR MEASURING GLUCOSE IN THE BODY
    211.
    发明申请
    NON-INVASIVE SYSTEM FOR MEASURING GLUCOSE IN THE BODY 审中-公开
    用于测量身体中葡萄糖的非入侵系统

    公开(公告)号：WO2006113476A2

    公开(公告)日：2006-10-26

    申请号：PCT/US2006/014152

    申请日：2006-04-13

    Applicant: BAYER HEALTHCARE LLC ,  REBEC, Mihailo, V.

    Inventor： REBEC, Mihailo, V.

    IPC: A61B5/1455

    CPC classification number: G01J3/1256 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1495 ,  A61B5/726 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0262 ,  G01J3/0272 ,  G01J3/10 ,  G01J3/28 ,  G01J3/433 ,  G01J2003/2866 ,  G01N21/35 ,  G01N2021/3144 ,  G01N2021/3185

    Abstract: A system for determining an analyte concentration in a fluid sample (e.g., glucose) comprises a light source, a detector, and a central processing unit. The detector is adapted to receive spectral information corresponding to light returned from the fluid sample being analyzed and to convert the received spectral information into an electrical signal indicative of the received spectral information. The central processing unit is adapted to compare the electrical signal to an algorithm built upon correlation with the analyte in body fluid. The algorithm is adapted to convert the received spectral information into the analyte concentration in body fluid. Spectral information is delivered from the central processing unit to the light source and used to vary the intensity and timing of the light to improve the accuracy of conversion into analyte concentration.

    Abstract translation: 用于确定流体样品（例如葡萄糖）中的分析物浓度的系统包括光源，检测器和中央处理单元。 检测器适于接收对应于正在分析的流体样品返回的光的光谱信息，并将接收到的光谱信息转换为指示所接收的光谱信息的电信号。 中央处理单元适于将电信号与建立在体液中分析物相关的算法进行比较。 该算法适用于将接收到的光谱信息转换成体液中的分析物浓度。 光谱信息从中央处理单元传送到光源，并用于改变光的强度和时间，以提高转换成分析物浓度的准确度。

    REDUCING SPECTRAL NOISE IN SEMICONDUCTOR SPECTROSCOPY SYSTEM
    212.
    发明申请
    REDUCING SPECTRAL NOISE IN SEMICONDUCTOR SPECTROSCOPY SYSTEM 审中-公开
    减少半导体光谱系统中的光谱噪声

    公开(公告)号：WO2006091274A1

    公开(公告)日：2006-08-31

    申请号：PCT/US2006/000823

    申请日：2006-01-10

    Applicant: AXSUN TECHNOLOGIES, INC. ,  ATIA, Walid, A. ,  FLANDERS, Dale, C.

    Inventor： ATIA, Walid, A. ,  FLANDERS, Dale, C.

    IPC: G01J3/10

    CPC classification number: G01J3/10 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0251 ,  G01J3/26 ,  G01J3/433

    Abstract: A spectroscopy system comprises a tunable semiconductor laser, such as an external cavity laser, that generates a tunable signal. A detector is provided for detecting the tunable signal after interaction with a sample. In this way, the system is able to determine the spectroscopic response of the sample by tuning the laser of the scan band and monitoring the detector's response. An integrating device, such as an integrating sphere, is interposed optically between the tunable semiconductor laser and the detector. This integrating device is used to mitigate the effects of parasitic spectral noise, such as noise that is generated by speckle or the combination of single- and multi-mode optical fibers in the transmission link between the tunable semiconductor laser and the detector.

    Abstract translation: 光谱系统包括可调谐半导体激光器，例如外腔激光器，其产生可调信号。 提供了一种检测器，用于在与样品相互作用后检测可调信号。 以这种方式，该系统能够通过调谐扫描带的激光并监测检测器的响应来确定样品的光谱响应。 诸如积分球的积分装置被光学地插入在可调半导体激光器和检测器之间。 该集成装置用于减轻寄生光谱噪声的影响，例如由可调谐半导体激光器和检测器之间的传输链路中的斑点或单模和多模光纤的组合产生的噪声。

    SYSTEM AND METHOD FOR MONITORING ENVIRONMENTAL EFFECTS USING OPTICAL SENSORS
    214.
    发明申请
    SYSTEM AND METHOD FOR MONITORING ENVIRONMENTAL EFFECTS USING OPTICAL SENSORS 审中-公开
    使用光学传感器监测环境影响的系统和方法

    公开(公告)号：WO2005078405A1

    公开(公告)日：2005-08-25

    申请号：PCT/US2004/004554

    申请日：2004-02-11

    Applicant: NEW FOCUS, INC.

    Inventor： PIETERSE, Jan-Willem ,  NGUYEN, Hoang ,  ABRIAM, Rosemary, O. ,  CORDES, Andrew, H.

    IPC: G01L01/24

    CPC classification number: G01J3/28 ,  G01D5/35303 ,  G01J3/1895 ,  G01J3/433

    Abstract: An apparatus and method for determining a physical parameter affecting an optical sensor or a number of sensors in a network. The apparatus uses a narrow linewidth source at an emission wavelength λ e and an arrangement for varying the emission wavelength λ e of the radiation. An analysis module with curve fitting is used to generate a fit to the response signal obtained from the optical sensor. The physical parameter is determined form the fit rather than from the response signal. The apparatus can be employed with Bragg gratings, etalons, Fabry Perot elements or other optical sensors.

    Abstract translation: 一种用于确定影响网络中的光学传感器或多个传感器的物理参数的装置和方法。 该装置使用发射波长长度的窄线宽源和用于改变辐射的发射波长的布置。 使用具有曲线拟合的分析模块来产生对从光学传感器获得的响应信号的拟合。 物理参数由合适而不是来自响应信号确定。 该装置可以与布拉格光栅，标准器，法布里珀罗元件或其他光学传感器一起使用。

    MULTISPECTRAL, MULTIFUSION, LASER-POLARIMETRIC OPTICAL IMAGING SYSTEM
    215.
    发明申请
    MULTISPECTRAL, MULTIFUSION, LASER-POLARIMETRIC OPTICAL IMAGING SYSTEM 审中-公开
    多光谱，多光谱，激光极向光学成像系统

    公开(公告)号：WO2005029015A2

    公开(公告)日：2005-03-31

    申请号：PCT/US2004/015046

    申请日：2004-05-13

    Applicant: THE UNIVERSITY OF AKRON ,  GIAKOS, George, C.

    Inventor： GIAKOS, George, C.

    IPC: G01J

    CPC classification number: G01J4/04 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0224 ,  G01J3/2823 ,  G01J3/36 ,  G01J3/433 ,  G01J3/447 ,  G01N21/21

    Abstract: A multi-energy polarization imaging method consisting of a multi-fusion, dual-rotating retarder / multiple-energy complete Mueller matrix-based polarimeter and dual-energy capabilities, has been invented. The term multifusion describes the use of several imaging functions altogether such as polarimetric imaging, dual-energy subtraction, multifocal imaging and other. By substracting polarimetric parameters such as degree of polarization, degree of linear polarization, degree of circular polarization, respectively, obtained with interrogation light beams of wavelengths λ 1 and λ 2 , he system, enhanced imaging is obtained. The system includes a light source for illuminating a target with a first quantity of light having a first wavelength and a second quantity of light having a second wavelength, the first and second wavelengths being different. A polarization-state generator generates a polarization state for each of the first and second quantities of light, and includes a first polarizer through which the first and second quantities of light are transmitted before entering a first waveplate. A polarization-state receiver evaluates a resulting polarization state of the first and second quantities of light following illumination of the target, the polarization-state receiver including a second waveplate through which the first and second quantittes of light are transmitted before entering a second polarizer. An optical image-capture device captures a first image of the target illuminated by the first quantity of light and a second image of the target illuminated by the second quantity of light. A processing unit assigns a weighting factor to at least one of the first and second images and evaluates a weighted difference between the first and second images to generate a multi-energy image of the target.

    Abstract translation: 已经发明了由多融合，双旋转延迟器/多能量完全Mueller基于矩阵的旋光仪和双能量能量组成的多能量偏振成像方法。 术语multifusion描述了几种成像功能的使用，例如极化成像，双能量减影，多焦点成像等。 通过减去分别用波长λ1和λ2的询问光束获得的极化度，极化度，线偏振度，圆偏振度等极化参数，他 系统，获得增强的成像。 该系统包括用于利用具有第一波长的第一光量和具有第二波长的第二光量照射目标的光源，第一和第二波长不同。 偏振态发生器为第一和第二光量中的每一个产生偏振态，并且包括第一偏振器，在进入第一波片之前，第一和第二光量通过该第一偏振器传输。 偏振态接收器评估在目标照射之后第一和第二光量的偏振状态，该偏振状态接收器包括第二波片，在进入第二偏振器之前，第一和第二量子光通过该第二波片传输。 光学图像捕获装置捕获由第一数量的光照射的目标的第一图像和由第二数量的光照射的目标的第二图像。 处理单元向第一和第二图像中的至少一个分配加权因子并评估第一和第二图像之间的加权差值以生成目标的多能量图像。

    METHOD AND APPARATUS FOR SPECTRUM ANALYSIS AND ENCODER
    216.
    发明申请
    METHOD AND APPARATUS FOR SPECTRUM ANALYSIS AND ENCODER 审中-公开
    光谱分析和编码器的方法和装置

    公开(公告)号：WO0000796A9

    公开(公告)日：2000-07-20

    申请号：PCT/US9914446

    申请日：1999-06-25

    Applicant: HAGLER THOMAS W

    Inventor： HAGLER THOMAS W

    IPC: G01J3/12 ,  G01J3/28 ,  G01J3/32 ,  G01J3/433

    CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0213 ,  G01J3/0229 ,  G01J3/0289 ,  G01J3/12 ,  G01J3/18 ,  G01J3/32 ,  G01J3/433 ,  G01J2001/4242 ,  G01J2003/2866

    Abstract: A disc serving as a spatial radiation modulator has dispersed radiation filters thereon. Each filter has a transmittance or reflectance modulation function of the form sin (m theta + p pi /4), where m is a positive integer and p has one of the four values 0, 1, 2, 3. A radiation beam including selected wavelength components is diffracted into an elongated image dispersed according to wavelength. Different wavelength components are focused onto different filters on the modulator and are encoded by corresponding filters. Since the modulation functions of the filters are orthogonal to one another, it is possible to extract the amplitude of each wavelength component after it has been encoded or modulated by corresponding filter from the total detected signal during one measurement.

    Abstract translation: 用作空间辐射调制器的盘在其上具有分散的辐射过滤器。 每个滤光器具有形式为sin 2（mθ+ p pi / 4）的透射率或反射率调制函数，其中m是正整数，p具有四个值0,1,2,3中的一个。辐射 包括所选择的波长分量的光束被衍射成根据波长分散的细长图像。 不同的波长分量聚焦在调制器上的不同滤波器上，并由相应的滤波器编码。 由于滤波器的调制功能彼此正交，因此可以在一次测量期间从总检测信号对相应的滤波器进行编码或调制之后提取每个波长分量的振幅。

    METHOD AND APPARATUS FOR SPECTRUM ANALYSIS AND ENCODER
    217.
    发明申请
    METHOD AND APPARATUS FOR SPECTRUM ANALYSIS AND ENCODER 审中-公开
    用于频谱分析和编码器的方法和设备

    公开(公告)号：WO0000796B1

    公开(公告)日：2000-05-18

    申请号：PCT/US9914446

    申请日：1999-06-25

    Applicant: HAGLER THOMAS W

    Inventor： HAGLER THOMAS W

    IPC: G01J3/12 ,  G01J3/28 ,  G01J3/32 ,  G01J3/433

    CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0213 ,  G01J3/0229 ,  G01J3/0289 ,  G01J3/12 ,  G01J3/18 ,  G01J3/32 ,  G01J3/433 ,  G01J2001/4242 ,  G01J2003/2866

    Abstract: A disc serving as a spatial radiation modulator has dispersed radiation filters thereon. Each filter has a transmittance or reflectance modulation function of the form sin (m theta + p pi /4), where m is a positive integer and p has one of the four values 0, 1, 2, 3. A radiation beam including selected wavelength components is diffracted into an elongated image dispersed according to wavelength. Different wavelength components are focused onto different filters on the modulator and are encoded by corresponding filters. Since the modulation functions of the filters are orthogonal to one another, it is possible to extract the amplitude of each wavelength component after it has been encoded or modulated by corresponding filter from the total detected signal during one measurement.

    Abstract translation: 用作空间辐射调制器的盘在其上散布有辐射滤波器。 每个滤波器具有sin 2（m theta + p pi / 4）形式的透射率或反射率调制函数，其中m是正整数并且p具有四个值0,1,2,3中的一个。辐射 包括选定波长分量的光束被衍射成根据波长分散的细长图像。 不同的波长成分被聚焦到调制器上的不同滤波器上，并由相应的滤波器进行编码。 由于滤波器的调制功能彼此正交，所以可以在一次测量期间从总检测信号中提取每个波长分量的幅度，在每个波长分量已经被相应的滤波器编码或调制之后。

    METHOD FOR IMPROVING THE SELECTIVITY OF SPECTROMETRIC MEASUREMENTS, AS WELL AS DEVICE FOR IMPLEMENTING SUCH METHOD
    218.
    发明申请
    METHOD FOR IMPROVING THE SELECTIVITY OF SPECTROMETRIC MEASUREMENTS, AS WELL AS DEVICE FOR IMPLEMENTING SUCH METHOD 审中-公开
    提高光谱测量选择性的方法，以及用于实施这种方法的设备

    公开(公告)号：WO1987000273A1

    公开(公告)日：1987-01-15

    申请号：PCT/EP1986000395

    申请日：1986-07-04

    Applicant: CAMMANN, Karl

    IPC: G01J03/433

    CPC classification number: H01J49/02 ,  G01J3/433 ,  G01N21/3103 ,  G01N21/6402

    Abstract: The selectivity, that is to say the ratio between the analyte-proportional signal and the foreign body-proportional signal is an essential factor in spectrometric measurements. When a narrow spectral band of the spectral domain is filtered by means of filter arrangements or the like and when supplying a detector of which the output signal is displayed, a sensitive improvement of the selectivity is obtained. The filter arrangement is periodically offset with respect to the spectral domain to be analyzed so that the spectral band passing through the filter arrangement is periodically offset through the spectral domain to be analyzed and the output signal from the detector is displayed through a lock-in amplifier of which the phase reference signal is proportional to the displacement.

    Abstract translation: 选择性，也就是说分析物比例信号与异物比例信号之间的比例是光谱测量中的一个重要因素。 当通过滤波器布置等过滤频域的窄谱带时，当提供显示输出信号的检测器时，可以获得敏感的选择性提高。 滤波器布置相对于要分析的频谱域周期性地偏移，使得通过滤波器装置的频谱带周期性地偏移通过待分析的频谱域，并且来自检测器的输出信号通过锁定放大器显示 其相位参考信号与位移成比例。

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