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    POSITIONING OF THE MEASURING VOLUME IN A SCANNING MICROSCOPIC METHOD
    231.
    发明申请
    POSITIONING OF THE MEASURING VOLUME IN A SCANNING MICROSCOPIC METHOD 审中-公开
    测量量的在扫描显微操作过程定位

    公开(公告)号：WO00037984A3

    公开(公告)日：2001-10-18

    申请号：PCT/EP1999/010142

    申请日：1999-12-21

    IPC: G01B11/24 ,  G01J3/02 ,  G01N21/17 ,  G01N21/47 ,  G01N21/64 ,  G01N21/65 ,  G01N33/483 ,  G02B21/00

    CPC classification number: G01J3/02 ,  G01J3/0237 ,  G01N21/6408 ,  G01N21/6445 ,  G01N21/6458 ,  G01N21/65 ,  G01N2021/6439 ,  G02B21/006 ,  G02B21/0068 ,  G02B21/0076 ,  G02B21/008

    Abstract: The invention relates to a method for optically detecting at least one entity arranged on a substrate (60). The at least one entity is scanned with a measuring volume (70) using at least one radiation source (10) and at least one set of confocal optics (32) or using a set of optics (32) configured for multi-photon excitation. Said entity essentially maintains the same position with regard to the substrate (60) and/or the support (61) for the duration of the recording of the measured values. An auxiliary focus (71) is generated before and/or during the scanning process while using at least one radiation source (11) and at least one set of optics (34). Said auxiliary focus lies at least partially on the contact surface (62) between the substrate (60) and the adjacent component or on another contact surface (62) located in a defined spatial relationship with regard to the entity. A retroreflection from the auxiliary focus (71) is detected in a confocal manner by at least one detector (21), is used for measuring the position of the contact surface (62) and is thus used for indirectly positioning the measuring volume (70). According to the inventive method, the position of the auxiliary focus (71) in relation to the measuring volume (70) can be adjusted in a defined manner.

    Abstract translation: 本发明涉及一种用于光学地检测至少一个实体，其被布置在基底（60）上的方法。 该至少一个实体进行扫描使用至少一个辐射源（10）和共焦光学系统（32）或设计用于多光子激发光学系统（32）的测量体积（70）。 它之前和/或所述支撑件（61）基本上为测量值的记录的持续时间保持其相对于所述基板（60）的位置。 之前和/或在扫描过程中的辅助聚焦（71）使用至少一个辐射源（11）和一个光学系统（34）产生的至少部分地在基底（60）和相邻部件或其他之间的界面（62）上 至固定实体接口（62）限定的空间关系。 从辅助聚焦（71）的背反射是由至少一个检测器（21）的共焦和用于测量接口（62），并且因此的位置来间接地定位使用的测量体积（70）检测。 在本发明方法中，辅助聚焦（71）相对于测量体积（70）的位置被限定可调节的。

    A FLUORESCENCE IMAGING SYSTEM
    232.
    发明申请
    A FLUORESCENCE IMAGING SYSTEM 审中-公开
    荧光成像系统

    公开(公告)号：WO1986002730A1

    公开(公告)日：1986-05-09

    申请号：PCT/SE1985000408

    申请日：1985-10-22

    Applicant: HIGHTECH NETWORK SCI AB ,  SVANBERG, Sune ,  MONTAN, Sune

    Inventor： HIGHTECH NETWORK SCI AB

    IPC: G01N21/64

    CPC classification number: G01N21/6456 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0237 ,  G01J3/36 ,  G01J2003/1239 ,  G01N2021/6421

    Abstract: A fluorescence imaging system includes a light source, preferably a pulsated laser (1), which irradiates an object, optionally via further optical components (2, 3, 5), so as to induce fluorescence radiation in the object. This radiation images the object on a detector plane (11). In accordance with the invention there is provided a beam-splitting system (6), such that the fluorescent object is reproduced in the form of at least three, and preferably four separate and mutually adjacent images. A selected filter is placed in each of the paths of these partial light beams. The detector plane has a plurality of image-point detectors each of which produces a respective electric signal, so that there is obtained for each image point at least three, and preferably four intensity signals recorded for a respective frequency band determined by respective filters. These signals are processed mathematically to provide a weighted signal value, which may be dimensionless. These weighted image-point values are reproduced, for example on a video-monitor (13), which makes possible fluorescence reproduction rich in contrast and free from disturbances with respect to spectral signatures. One example of the use to which the invention can be put is the detection of cancer cells to which a fluorescence signature has been imparted with the aid of HPD.

    Abstract translation: 荧光成像系统包括光源，优选脉动激光器（1），其可选地经由另外的光学部件（2,3,5）照射物体，以便在物体中诱导荧光辐射。 该辐射将物体在检测器平面（11）上成像。 根据本发明，提供一种分束系统（6），使得荧光物体以至少三个，优选四个分开且相互相邻的图像的形式再现。 选择的滤光器被放置在这些部分光束的每个路径中。 检测器平面具有多个图像点检测器，每个图像点检测器产生相应的电信号，从而为每个图像点获得针对由各个滤波器确定的相应频带记录的至少三个，最好是四个强度信号。 这些信号在数学上被处理以提供加权信号值，其可以是无量纲的。 这些加权图像点值例如在视频监视器（13）上再现，这使得可能的荧光再现富有对比度并且没有关于光谱特征的干扰。 可以放置本发明的用途的一个实例是在HPD的帮助下检测已经赋予了荧光标记的癌细胞。

    INTEGRATED SPECTROMETER AND OPTOMECHANICAL SENSOR
    233.
    发明公开
    INTEGRATED SPECTROMETER AND OPTOMECHANICAL SENSOR 审中-公开

    公开(公告)号：EP3400427A1

    公开(公告)日：2018-11-14

    申请号：EP17700161.7

    申请日：2017-01-06

    Applicant: Technische Universiteit Eindhoven

    Inventor： FIORE, Andrea ,  VAN DER HEIJDEN, Robertus Willebrordus ,  MIDOLO, Leonardo ,  ZOBENICA, Zarco ,  LIU, Tianran

    IPC: G01J3/02 ,  G01J3/26 ,  G01J3/12

    CPC classification number: G01J3/0256 ,  G01J3/0205 ,  G01J3/0237 ,  G01J3/26 ,  G01J2003/1213

    Abstract: A double membrane microspectrometer is provided that includes a first membrane having a first and second doped semiconductor layers, and a first intrinsic layer is disposed between the first and second layers, where the first intrinsic layer includes an optically absorbing material, a first pattern of through holes are disposed perpendicular through the first membrane having lateral support arms, a second membrane having a third doped layer and a fourth layer is an intrinsic layer or a doped layer, where the second membrane includes a second pattern of through holes, where the first membrane is separated from the second membrane by an insulating bridge layer and is supported above the second membrane by lateral support arms, where an absorption spectrum of the absorbing material is dependent on the separation distance of the membranes, electrodes are disposed on the first layer, the second layer, and the third layer operate the separation.

    SYSTEM METHOD AND APPARATUS FOR SELECTING AND CONTROLLING LIGHT SOURCE BANDWIDTH
    235.
    发明公开
    SYSTEM METHOD AND APPARATUS FOR SELECTING AND CONTROLLING LIGHT SOURCE BANDWIDTH 审中-公开
    SYSTEM，VERFAHREN UND VORRICHTUNG ZUR AUSWAHL UND STEUERUNG EINER LICHTQUELLENBANDBREITE

    公开(公告)号：EP2351169A4

    公开(公告)日：2017-08-30

    申请号：EP09822830

    申请日：2009-10-24

    Applicant: CYMER LLC

    Inventor： FIGUEROA EFRAIN ,  PARTLO WILLIAM N ,  ALGOTS JOHN MARTIN

    IPC: H01S3/10 ,  G01J3/02 ,  G01J3/06 ,  G01J3/12 ,  G01J3/14 ,  G01J3/18 ,  G02B5/18 ,  H01S3/08 ,  H01S3/1055 ,  H01S3/106

    CPC classification number: H01S3/08009 ,  G01J3/02 ,  G01J3/0237 ,  G01J3/027 ,  G01J3/06 ,  G01J3/14 ,  G01J3/18 ,  G01J2003/1208 ,  G02B5/1828 ,  H01S3/08004 ,  H01S3/1055 ,  H01S3/1067

    Abstract: The bandwidth selection mechanism includes a first actuator mounted on a second face of a dispersive optical element, the second face being opposite from a reflective face, the first actuator having a first end coupled to a first end block and a second end coupled to a second end block, the first actuator being operative to apply equal and opposite forces to the first end block and the second end block to bend the body of the dispersive optical element along the longitudinal axis of the body and in a first direction normal to the reflective face of the dispersive optical element. The bandwidth selection mechanism also includes a second actuator being operative to apply equal and opposite forces to bend the body along the longitudinal axis of the body, in a second direction perpendicular to the reflective face of the dispersive optical element.

    Abstract translation: 带宽选择机构包括安装在色散光学元件的第二面上的第一致动器，第二面与反射面相对，第一致动器具有耦合到第一端块的第一端和耦合到第二端的第二端 所述第一致动器可操作以将相等且相反的力施加到所述第一端块和所述第二端块上，以使所述色散光学元件的所述主体沿所述主体的所述纵向轴线弯曲，并沿垂直于所述反射面的第一方向弯曲 的色散光学元件。 带宽选择机构还包括第二致动器，第二致动器可操作以在垂直于色散光学元件的反射面的第二方向上施加相等且相反的力以沿着主体的纵向轴线弯曲主体。

    USER DEVICE COMPRISING A CAMERA AND A SPECTROMETER MODULE
    236.
    发明公开
    USER DEVICE COMPRISING A CAMERA AND A SPECTROMETER MODULE 审中-公开
    包括摄像机和光谱仪模块的用户设备

    公开(公告)号：EP3184976A1

    公开(公告)日：2017-06-28

    申请号：EP15202382.6

    申请日：2015-12-23

    Applicant: IMEC VZW

    Inventor： BORREMANS, Jonathan ,  LAMBRECTHS, Andy ,  BARON, Jerome

    IPC: G01J3/02 ,  G01J3/28

    CPC classification number: H04N5/332 ,  G01C3/08 ,  G01J3/0237 ,  G01J3/0248 ,  G01J3/0278 ,  G01J3/28 ,  G01J3/2823 ,  G01J2003/2826 ,  G06T7/90 ,  G06T2207/10016 ,  H04N5/23212 ,  H04N5/23222 ,  H04N5/23293

    Abstract: According to an aspect of the invention, there is provided a user device comprising:
    a camera adapted to acquire at least one image of a scenery which falls within a field of view of the camera,
    a spectrometer module adapted to acquire spectral information from a region within the scenery which region falls within a field of view of the spectrometer module, and
    a processing unit adapted to determine based on information relating the field of view of the spectrometer module to the field of view of the camera, a spectrometer module target area, within said at least one image, corresponding to the region and to output display data to a screen of the user device for providing an indication of the target area on the display.

    Abstract translation: 根据本发明的一个方面，提供了一种用户设备，包括：照相机，适用于获取落入照相机的视场内的景物的至少一个图像;光谱仪模块，适于从区域获取光谱信息 在所述区域落入所述光谱仪模块的视场内的景物内;以及处理单元，适于基于与所述光谱仪模块的视场与所述照相机的所述视场相关的信息来确定光谱仪模块目标区域， 在所述至少一个图像内对应于所述区域并将显示数据输出到所述用户设备的屏幕，用于在所述显示器上提供所述目标区域的指示。

    WAVELENGTH TUNABLE BIREFRINGENT FILTER
    237.
    发明公开
    WAVELENGTH TUNABLE BIREFRINGENT FILTER 审中-公开
    多功能过滤器MIT ABSTIMMBARERWELLENLÄNGE

    公开(公告)号：EP3136156A1

    公开(公告)日：2017-03-01

    申请号：EP16185366.8

    申请日：2016-08-23

    Applicant: Luceo Co., Ltd.

    Inventor： ICHIMOTO, Kiyoshi ,  YOSHIMURA, Kensho ,  SAKASHITA, Ryuichi ,  HONDA, Umehiko ,  HANASHIMA, Masakazu ,  SEO, Kazuhiro

    IPC: G02B27/28 ,  H01S3/106 ,  G02B7/00 ,  G01J3/12 ,  G01J3/02

    CPC classification number: G02B26/007 ,  G01J3/0224 ,  G01J3/0237 ,  G01J3/12 ,  G01J3/447 ,  G01J2003/1213 ,  G02B5/3083 ,  G02B7/006 ,  G02B27/288 ,  H01S3/1062

    Abstract: A wavelength tunable filter (200) selectively transmitting light of any desired wavelength within the range of 450 nm to 1100 nm without using a band pass filter is disclosed. The wavelength tunable filter (200) comprises a plurality of polarizers (101a to 101f) and a plurality of units between the adjacent polarizers (101 a to 101f) on a common optical axis (111) in a housing (201). Each unit has, in order from light incident side, a quartz birefringent plate (102), an ultra-wide band 1/4 waveplate (103) and an ultra-wide band 1/2 waveplate (104). The ultra-wide band 1/2 waveplate (104) is accommodated in a cylindrical rotatable body (303; 403; 503) and it is rotated by a rotating mechanism.

    Abstract translation: 公开了一种波长可调滤波器（200），其不使用带通滤波器选择性地透射450nm至1100nm范围内的任何所需波长的光。 波长可调滤波器（200）包括多个偏振器（101a至101f）以及在壳体（201）中的公共光轴（111）上的相邻偏振器（101a至101f）之间的多个单元。 每个单元具有从光入射侧起的顺序为石英双折射板（102），超宽带1/4波片（103）和超宽带1/2波片（104）。 超宽带1/2波片（104）容纳在圆筒状的旋转体（303; 403; 503）中，并通过旋转机构旋转。

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