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    Polymeric nanopillars and nanotubes, their manufacture and uses
    251.
    发明授权
    Polymeric nanopillars and nanotubes, their manufacture and uses 有权

    公开(公告)号：US09718676B2

    公开(公告)日：2017-08-01

    申请号：US12440546

    申请日：2007-09-12

    Applicant: Steven A. Soper ,  Robin L. McCarley ,  Guofang Chen ,  Hamed Shadpour

    Inventor： Steven A. Soper ,  Robin L. McCarley ,  Guofang Chen ,  Hamed Shadpour

    IPC: B82B3/00 ,  G01N27/26 ,  G01N33/561 ,  B81C1/00 ,  G01N27/447

    CPC classification number: B81C1/00111 ,  B81C2201/034 ,  G01N27/44773 ,  Y10T428/2982

    Abstract: A method is disclosed for fabricating free-standing polymeric nanopillars or nanotubes with remarkably high aspect ratios. The nanopillars and nanotubes may be used, for example, in integrated microfluidic systems for rapid, automated, high-capacity analysis or separation of complex protein mixtures or their enzyme digest products. One embodiment, preferably fabricated entirely from polymer substrates, comprises a cell lysis unit; a solid-phase extraction unit with free-standing, polymeric nanostructures; a multi-dimensional electrophoretic separation unit with high peak capacity; a solid-phase nanoreactor for the proteolytic digestion of isolated proteins; and a chromatographic unit for the separation of peptide fragments from the digestion of proteins. The nanopillars and nanotubes may also be used to increase surface area for reaction with a solid phase, for example, with immobilized enzymes or other catalysts within a microchannel, or as a solid support for capillary electrochromatography-based separations of proteins or peptides.

    Three Dimensional Microstructures And Fabrication Process
    253.
    发明申请
    Three Dimensional Microstructures And Fabrication Process 有权
    三维微结构和制作工艺

    公开(公告)号：US20160194200A1

    公开(公告)日：2016-07-07

    申请号：US14985859

    申请日：2015-12-31

    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

    Inventor： Khalil NAJAFI ,  Tal Nagourney ,  Jae Yoong CHO

    IPC: B81C99/00 ,  B22D25/02 ,  C03B23/035 ,  B22D23/06

    CPC classification number: B81C99/0085 ,  B22D23/06 ,  B22D25/02 ,  B81C2201/034 ,  C03B23/02 ,  C03B23/0302 ,  C03B23/0352 ,  C03B23/0355 ,  C03B23/0357

    Abstract: A method for fabricating three-dimensional microstructures is presented. The method includes: disposing a substantially planar reflow material between two molds; heating the reflow material while the reflow material is disposed between the two molds; and reflowing the reflow material towards the bottom surface of one of the molds by creating a pressure gradient across the reflow material. At least one of molds includes geometrics features that help to shape the reflow material and thereby form a complex three-dimensional microstructure.

    Abstract translation: 提出了制作三维微结构的方法。 该方法包括：在两个模具之间布置基本上平面的回流材料; 在回流材料设置在两个模具之间时加热回流材料; 并且通过在回流材料上产生压力梯度将回流材料回流到其中一个模具的底表面。 模具中的至少一个包括几何特征，其有助于形成回流材料，从而形成复杂的三维微结构。

    AEROGEL-BASED MOLD FOR MEMS FABRICATION AND FORMATION THEREOF
    254.
    发明申请
    AEROGEL-BASED MOLD FOR MEMS FABRICATION AND FORMATION THEREOF 有权
    用于MEMS制造及其形成的基于AIRGEL的模具

    公开(公告)号：US20140349078A1

    公开(公告)日：2014-11-27

    申请号：US14455745

    申请日：2014-08-08

    Applicant: Honeywell International Inc.

    Inventor： Robert Jon Carlson

    IPC: B29C33/38 ,  B81B7/00 ,  B29C41/00 ,  B29C59/16 ,  B29C59/14

    CPC classification number: B29C33/3842 ,  B29C41/00 ,  B29C59/14 ,  B29C59/16 ,  B29K2909/00 ,  B29K2995/0037 ,  B81B7/00 ,  B81B2201/05 ,  B81B2201/058 ,  B81B2203/0127 ,  B81C99/009 ,  B81C2201/0132 ,  B81C2201/0143 ,  B81C2201/034 ,  C23F1/02 ,  H01L21/30604 ,  Y10T428/24496

    Abstract: The invention is directed to a patterned aerogel-based layer that serves as a mold for at least part of a microelectromechanical feature. The density of an aerogel is less than that of typical materials used in MEMS fabrication, such as poly-silicon, silicon oxide, single-crystal silicon, metals, metal alloys, and the like. Therefore, one may form structural features in an aerogel-based layer at rates significantly higher than the rates at which structural features can be formed in denser materials. The invention further includes a method of patterning an aerogel-based layer to produce such an aerogel-based mold. The invention further includes a method of fabricating a microelectromechanical feature using an aerogel-based mold. This method includes depositing a dense material layer directly onto the outline of at least part of a microelectromechanical feature that has been formed in the aerogel-based layer.

    Abstract translation: 本发明涉及用作至少部分微机电特征的模具的图案化气凝胶基层。 气凝胶的密度小于MEMS制造中使用的典型材料的密度，例如多晶硅，氧化硅，单晶硅，金属，金属合金等。 因此，可以以明显高于在较致密的材料中形成结构特征的速率的速率在气凝胶层中形成结构特征。 本发明还包括一种图案化气凝胶层以产生这种基于气凝胶的模具的方法。 本发明还包括使用基于气凝胶的模具制造微机电特征的方法。 该方法包括将致密材料层直接沉积在已经形成在气凝胶层中的微机电特征的至少一部分的轮廓上。

    HIGH ASPECT RATIO POLYMER ELONGATE AND ONE-DIMENSIONAL MICRO STRUCTURE FABRICATION
    256.
    发明申请
    HIGH ASPECT RATIO POLYMER ELONGATE AND ONE-DIMENSIONAL MICRO STRUCTURE FABRICATION 审中-公开
    高倍率聚合物高分子和一维微结构制造

    公开(公告)号：US20140127508A1

    公开(公告)日：2014-05-08

    申请号：US14068224

    申请日：2013-10-31

    Applicant: The Board of Trustees of the University of llinois

    Inventor： M. Taher A. Saif ,  Jagannathan Rajagopalan

    IPC: B29C45/40

    CPC classification number: B29C33/42 ,  B01L3/502707 ,  B01L2300/0627 ,  B01L2300/0816 ,  B01L2300/123 ,  B29K2083/00 ,  B29L2031/753 ,  B29L2031/756 ,  B81B2201/0214 ,  B81B2201/058 ,  B81B2203/0118 ,  B81C99/0085 ,  B81C2201/034 ,  Y10T428/298

    Abstract: A preferred method of the invention introduces organosilicon polymer into the reservoir of a mold with trenches defining a negative mold impression of a feature that has a high aspect ratio in fluid communication with the micro-dimensioned reservoir. The mold is preferably coated with a low-stiction coating. The polymer is moved via capillary action into the negative mold from the reservoir. The polymer is cured. The polymer is then released from the mold. Preferably, the polymer is soaked in a releasing solution prior to release. Preferably, the polymer is released by gripping cured polymer in the reservoir and gently peeling the cured micropolymer from the mold. In preferred embodiments, the polymer is poly-dimethyl-siloxane (PDMS). A preferred structure formed by methods of the invention is polymer microbeam in a liquid having a length of one to a few millimeters and a stiffness of k

    Abstract translation: 本发明的优选方法将有机硅聚合物引入到具有沟槽的模具的储存器中，沟槽限定了具有与微尺寸储存器流体连通的高纵横比的特征的负模印迹。 模具优选地涂覆有低粘度涂层。 聚合物通过毛细作用移动到储存器的负模具中。 聚合物固化。 然后将聚合物从模具中释放出来。 优选地，在释放之前将聚合物浸泡在释放溶液中。 优选地，聚合物通过将固化的聚合物夹持在储存器中并从模具轻轻剥离固化的微聚合物来释放。 在优选的实施方案中，聚合物是聚二甲基硅氧烷（PDMS）。 通过本发明的方法形成的优选结构是在长度为1至几毫米且刚度为k <0.1pN /μm的液体中的聚合物微束。 可以与梁一起创建气动特征。 优选的微束可以是十或几十微米深，宽和毫米或几毫米长。

    METHOD OF FORMING STRUCTURED SINTERED ARTICLES
    259.
    发明申请
    METHOD OF FORMING STRUCTURED SINTERED ARTICLES 审中-公开
    形成结构化烧结物品的方法

    公开(公告)号：US20100276846A1

    公开(公告)日：2010-11-04

    申请号：US12831701

    申请日：2010-07-07

    Applicant: Diane Kimberlie Guilfoyle ,  Paul John Shustack ,  Lung-Ming Wu

    Inventor： Diane Kimberlie Guilfoyle ,  Paul John Shustack ,  Lung-Ming Wu

    IPC: B29C35/08

    CPC classification number: C03C17/28 ,  B81B2201/058 ,  B81C1/00071 ,  B81C2201/034 ,  C03B19/06 ,  C03C11/00 ,  C03C17/04 ,  C03C17/324 ,  C03C23/0005

    Abstract: Disclosed is a method of forming a structured sintered article including providing a mixture comprising a sinterable particulate material and a binder, the binder comprising, as a function of total resin content of the binder, at least 50% by weight of a thermoplastic binder material and at least 5% by weight of a radiation-curable binder material; shaping the mixture with a mold to form a structure; setting the structure by cooling the structure or by allowing the structure to cool; separating the structure from the mold; irradiating the structure so as to at least partially cure the radiation-curable binder material, and debinding and sintering the structure so as to form a structured sintered article. Shaping may include forming a structure having one or more open channels, and sintering may include sintering in together in contact with at least one additional structure so as to cover or enclose the channels.

    Abstract translation: 公开了一种形成结构化烧结制品的方法，包括提供包含可烧结颗粒材料和粘合剂的混合物，所述粘合剂包含作为粘合剂的总树脂含量的函数，至少50重量％的热塑性粘合剂材料和 至少5重量％的可辐射固化粘合剂材料; 用模具成型混合物以形成结构; 通过冷却结构或通过使结构冷却来设定结构; 将结构与模具分离; 照射该结构以至少部分地固化可辐射固化的粘合剂材料，以及脱结和烧结该结构以便形成结构化的烧结制品。 成形可以包括形成具有一个或多个开放通道的结构，并且烧结可以包括与至少一个附加结构接触在一起的烧结以覆盖或封闭通道。

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