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    PUMP HEAD OUTLET PORT
    23.
    发明申请
    PUMP HEAD OUTLET PORT 审中-公开
    泵头出口口

    公开(公告)号：WO2012122442A3

    公开(公告)日：2013-10-17

    申请号：PCT/US2012028408

    申请日：2012-03-09

    Applicant: WATERS TECHNOLOGIES CORP ,  SHREVE JOSHUA A ,  ALMEIDA NEAL ,  ANGELOSANTO JOHN

    Inventor： SHREVE JOSHUA A ,  ALMEIDA NEAL ,  ANGELOSANTO JOHN

    IPC: H04W16/04

    CPC classification number: F04B53/164 ,  F04B13/00 ,  F04B53/007 ,  F04B53/06 ,  G01N30/32 ,  G01N2030/326

    Abstract: Pumps used in liquid chromatography applications employ actuators for pressurizing and moving liquid. An actuator includes a pump head having a chamber, a gland, a movable rod extending through the gland into the chamber of the pump head, and a plunger seal disposed in the gland around the rod for sealing against fluidic leakage from the chamber. The plunger seal has an annular flange that provides an OD (outer diameter) seal against the gland. The flange defines a seal cavity. The pump head further includes an outlet port and an outlet channel. One end of the outlet channel is in communication with the outlet port and the other end of the outlet channel opens into the seal cavity of the plunger seal. The outlet channel provides a flow path for liquid in the chamber to travel towards the outlet port in response to movement of the rod.

    Abstract translation: 用于液相色谱应用的泵使用用于加压和移动液体的致动器。 致动器包括泵头，其具有腔室，密封套，通过压盖延伸到泵头的腔室中的活动杆以及设置在杆周围的压盖中的活塞密封件，用于密封以防止来自腔室的流体泄漏。 柱塞密封件具有环形凸缘，其向压盖提供OD（外径）密封。 凸缘限定密封腔。 泵头还包括出口和出口通道。 出口通道的一端与出口连通，出口通道的另一端通向柱塞密封的密封腔。 出口通道为腔室中的液体提供流动路径，以响应于棒的移动朝向出口移动。

    APPARATUS AND METHODS FOR MAKING ANALYTE PARTICLES
    24.
    发明申请
    APPARATUS AND METHODS FOR MAKING ANALYTE PARTICLES 审中-公开
    用于制备分析颗粒的装置和方法

    公开(公告)号：WO2009117312A2

    公开(公告)日：2009-09-24

    申请号：PCT/US2009037043

    申请日：2009-03-13

    Applicant: WATERS TECHNOLOGIES CORP ,  JARRELL JOSEPH J

    Inventor： JARRELL JOSEPH J

    IPC: G01N30/14

    CPC classification number: G01N30/84 ,  G01N30/74 ,  G01N2030/847 ,  G01N21/47

    Abstract: A device for making particulate analyte molecules comprising a nebulizer producing a plume of liquid droplets, a vessel having a chamber to receive the plume in which the chamber has a nebulization section, a desolvation section. The nebulization section is cooled to form a condensed waste from a portion of said plume. The desolvation section is heated to form solvent gas molecules and particulate analyte molecules.

    Abstract translation: 一种用于制造颗粒分析物分子的装置，其包括产生液滴的雾化器的雾化器，具有容纳腔室的腔室的容器，其中腔室具有雾化部分，去溶剂化部分。 雾化部分被冷却以形成来自所述羽流的一部分的冷凝废料。 去溶剂化部分被加热以形成溶剂气体分子和颗粒分析物分子。

    SYSTEMS, METHODS AND DEVICES ADDRESSING SAMPLE EXTRACTION AND INJECTION PROBLEMS IN CHROMATOGRAPHY
    25.
    发明申请
    SYSTEMS, METHODS AND DEVICES ADDRESSING SAMPLE EXTRACTION AND INJECTION PROBLEMS IN CHROMATOGRAPHY 审中-公开
    处理色谱中的样品提取和注射问题的系统，方法和装置

    公开(公告)号：WO2017127516A8

    公开(公告)日：2017-08-24

    申请号：PCT/US2017014092

    申请日：2017-01-19

    Applicant: WATERS TECHNOLOGIES CORP

    Inventor： TARAFDER ABHIJIT

    IPC: G05D7/06 ,  B01D15/18 ,  G01N30/16

    CPC classification number: B01D17/12 ,  B01D11/0219 ,  G01N1/4055 ,  G01N30/02 ,  G01N35/1097 ,  G01N2001/4061 ,  G01N2035/0444

    Abstract: In a chromatography system, including within the system an extraction vessel which receives a mixture of mobile phase and co-solvent and provides a mixture of mobile phase and co-solvent with sample to a chromatography column to increase sample concentration within the mixture. In addition, adding a reservoir to the chromatography system to form an extraction-pressurization system, wherein the mixture with sample may be collected in the reservoir and may diffuse and equilibrate to an approximately uniform sample concentration before being provided to the chromatography column. Also in addition, providing a plurality of extraction-pressurization systems to allow near-simultaneous extraction of sample and loading of the column, or concurrent extraction and loading by the plurality of extraction-pressurization systems.

    Abstract translation: 在色谱系统中，包括系统内的提取容器，其接收流动相和共溶剂的混合物，并将流动相和共溶剂与样品的混合物提供给色谱柱以增加混合物内的样品浓度。 另外，向色谱系统添加储库以形成提取 - 加压系统，其中与样品的混合物可以被收集在储库中并且可以在被提供给色谱柱之前扩散并且平衡成大致均匀的样本浓度。 另外，提供多个抽取 - 加压系统以允许近乎同时地抽取样本并装载柱，或者通过多个抽取 - 加压系统同时抽取和装载。

    ROTARY SELECTOR VALVE AND ASSOCIATED SYSTEMS AND METHODS
    28.
    发明申请
    ROTARY SELECTOR VALVE AND ASSOCIATED SYSTEMS AND METHODS 审中-公开
    旋转选择阀和相关系统和方法

    公开(公告)号：WO2014047108A8

    公开(公告)日：2014-05-15

    申请号：PCT/US2013060291

    申请日：2013-09-18

    Applicant: WATERS TECHNOLOGIES CORP

    Inventor： JENCKS ROBERT A ,  MOELLER MARK W

    IPC: G01N30/36

    CPC classification number: G01N30/36 ,  F16K11/07 ,  F16K11/0743 ,  G01N30/34 ,  Y10T137/0318 ,  Y10T137/86541 ,  G01N2030/202 ,  B01D15/40

    Abstract: Exemplary embodiments are directed to a rotary selector valve that includes a valve body that includes a rotor and a stator. The stator includes a first port for flow of a first flow material and a second port for flow of a second flow material. The rotor includes a groove for flow of at least one of the first flow material and the second flow material. The rotor includes a vent groove disposed between the first port and the second port for venting at least a portion of at least one of the first flow material and the second flow material to an exterior of the valve body. Exemplary methods of operating a rotary selector valve and C02-based chromatography flow systems including a rotary selector valve are also provided.

    Abstract translation: 示例性实施例涉及一种旋转选择阀，其包括包括转子和定子的阀体。 定子包括用于第一流动材料流动的第一端口和用于第二流动材料流动的第二端口。 转子包括用于流动第一流动材料和第二流动材料中的至少一个的凹槽。 转子包括布置在第一端口和第二端口之间的通气槽，用于将第一流动材料和第二流动材料中的至少一个的至少一部分排放到阀体的外部。 还提供了操作旋转选择阀和包括旋转选择阀的基于CO 2的色谱流动系统的示例性方法。

    SYSTEM AND METHOD OF COOLING A PUMP HEAD USED IN CHROMATOGRAPHY
    29.
    发明申请
    SYSTEM AND METHOD OF COOLING A PUMP HEAD USED IN CHROMATOGRAPHY 审中-公开
    冷却在色谱中使用的泵头的系统和方法

    公开(公告)号：WO2012122361A3

    公开(公告)日：2014-04-17

    申请号：PCT/US2012028246

    申请日：2012-03-08

    Applicant: WATERS TECHNOLOGIES CORP ,  JOUDREY KURT D ,  LINDERSON PAUL E

    Inventor： JOUDREY KURT D ,  LINDERSON PAUL E

    IPC: F04B53/08

    CPC classification number: B01D15/40 ,  F04B53/08 ,  F04B53/16 ,  F28D1/00 ,  G01N30/32 ,  G01N2030/326 ,  G01N30/30

    Abstract: Disclosed is a system and method of cooling a pump head by transferring heat to the actuator body, which is joined to the pump head via a support plate. In some embodiments the heat transfer is accomplished by means of two conductive plates, one placed on either side of the support plate between it and the pump head and actuator body. In some embodiments the heat transfer is controlled by a thermoelectric device. Also disclosed is a second system and method of cooling fluid to move through a pump head by pre-chilling it.

    Abstract translation: 公开了一种通过将热传递到致动器主体来冷却泵头的系统和方法，致动器主体经由支撑板连接到泵头。 在一些实施例中，热传递通过两个导电板来实现，一个放置在支撑板的与泵头和致动器本体之间的任一侧上。 在一些实施例中，热传导由热电装置控制。 还公开了冷却流体以通过预冷而移动通过泵头的第二系统和方法。

    METHOD, SYSTEM AND APPARATUS FOR AUTOMATIC CALIBRATION OF A NEEDLE VALVE DEVICE IN A PRESSURIZED FLOW SYSTEM
    30.
    发明申请
    METHOD, SYSTEM AND APPARATUS FOR AUTOMATIC CALIBRATION OF A NEEDLE VALVE DEVICE IN A PRESSURIZED FLOW SYSTEM 审中-公开
    用于加压流动系统中针阀装置自动校准的方法，系统和装置

    公开(公告)号：WO2013134496A3

    公开(公告)日：2013-10-31

    申请号：PCT/US2013029580

    申请日：2013-03-07

    Applicant: WATERS TECHNOLOGIES CORP

    Inventor： SHREVE JOSHUA A ,  KEENAN PAUL ,  HILL RYAN ,  MAILLET JOHN

    IPC: C12Q1/68

    CPC classification number: F16K27/02 ,  B01D15/40 ,  F16K1/38 ,  F16K31/0655 ,  G01N30/20 ,  G01N30/32 ,  Y10T137/0486 ,  Y10T137/6065

    Abstract: Exemplary embodiments are directed to apparatus, systems and methods used in connection with a needle valve device operating in a pressurized flow system. The apparatus, systems and methods provide for automatic positioning of a needle relative to a seat in the needle valve device to provide consistent calibration with minimal user interaction after a maintenance event or upon a start-up of the pressurized flow system. The apparatus, systems and methods utilize a calibration collar secured to a shaft of an actuator within the needle valve device. The calibration collar includes one or more locking mechanism and a spring.

    Abstract translation: 示例性实施例涉及结合在加压流动系统中操作的针阀装置使用的装置，系统和方法。 该装置，系统和方法提供针头相对于针阀装置中的座位的自动定位，以在维护事件之后或加压流动系统启动时以最小的用户交互提供一致的校准。 该装置，系统和方法利用固定到针阀装置内的致动器的轴上的校准套环。 校准套环包括一个或多个锁定机构和弹簧。

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