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公开(公告)号：KR1020170064622A
公开(公告)日：2017-06-12
申请号：KR1020150170057
申请日：2015-12-01
Applicant: 성균관대학교산학협력단
Abstract: 본발명은플라즈마멸균기및 플라즈마멸균기의과산화수소기체발생장치에관한것으로서, 본발명에따른플라즈마멸균기는멸균챔버를 100torr 이상의상압(준상압)으로형성한다음, 비활성기체를이용하여플라즈마를발생시키고, 발생된플라즈마에의해과산화수소기체로부터 OH 라디컬을생성시킴으로써멸균대상을멸균시키며, 이때비활성기체를이용하여과산화수소기체를생성하는것을특징으로한다.
Abstract translation: 本发明涉及在等离子体灭菌器和等离子体灭菌装置中产生气体的过氧化氢，根据本发明的等离子体灭菌器生成在常压下灭菌室至100托或更多的形成（标准大气压），然后，产生的等离子体使用惰性气体， 通过生成OH由等离子体从过氧化氢的气体基团sikimyeo灭菌灭菌目标，此时使用的惰性气体的特征在于，以产生过氧化氢的气体。
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公开(公告)号：KR101374409B1
公开(公告)日：2014-03-18
申请号：KR1020110105985
申请日：2011-10-17
Applicant: 성균관대학교산학협력단
IPC: A61K31/497 , A61K31/495 , A61P31/00
CPC classification number: A61K31/495 , A61K31/345 , A61K31/496 , Y02A50/475 , Y02A50/483
Abstract: 본 발명은 비유전성 항생제 내성을 가지는 미생물에게 항생제에 대한 감수성을 부여할 수 있는 화합물을 항생제와 함께 처리하여 비유전성 항생제 내성을 가지는 미생물을 사멸시키는 방법, 상기 화합물을 포함하는 항생제 내성 억제용 조성물 및 항생제와 상기 화합물을 유효성분으로 포함하는 미생물감염성 질환의 예방 또는 치료용 약학 조성물에 관한 것이다. 본 발명의 화합물은 다양한 항생제에 투여시 나타나는 비유전적 항생제 내성을 억제하여 이에 의한 2차 감염을 방지할 수 있으므로, 항생제를 이용하여 미생물감염증을 효과적으로 예방 또는 치료하는데 널리 활용될 수 있을 것이다.
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公开(公告)号：KR101373997B1
公开(公告)日：2014-03-12
申请号：KR1020120088641
申请日：2012-08-13
Applicant: 성균관대학교산학협력단
Abstract: 본 발명은 비만세포의 탈과립에 관여하는 SNARE(soluble NSF attachment protein receptor) 복합체 형성 저해능을 확인함으로써, 항알러지 물질을 스크리닝하는 방법에 관한 것이다. 본 발명의 방법을 이용하면, 항알러지 물질을 효과적으로 스크리닝하여 알러지 질환 개선 및 치료 물질의 개발에 이용할 수 있으며, 본 발명에서 확인한 결과를 바탕으로 알러지의 메커니즘을 보다 효과적으로 연구할 수 있는 장점이 있다.
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公开(公告)号：KR1020130139820A
公开(公告)日：2013-12-23
申请号：KR1020130148792
申请日：2013-12-02
Applicant: 성균관대학교산학협력단
IPC: A61K31/497 , A61K31/496 , A61K31/495 , A61K31/34 , A61P31/00
CPC classification number: Y02A50/475 , Y02A50/483 , A61K31/496 , A61K31/341 , A61K31/495
Abstract: The present invention relates to a method for killing microorganisms having non-inherited antibiotic resistance by processing an antibiotic with a compound which can add sensitivity for the antibiotic to the microorganism having the non-inherited antibiotic resistance; to a compound for suppressing antibiotic resistance which includes the compound; and to a pharmaceutical composition for preventing or treating microorganism infectious diseases which includes the compound as an active ingredient. The compound of the present invention suppresses the non-inherited antibiotic resistance which is shown when administered to various antibiotics in order to prevent secondary infections caused thereby and to effectively prevent or treat the microorganism infectious diseases using the antibiotic.
Abstract translation: 本发明涉及通过用具有抗生素对具有非遗传抗生素抗性的微生物增加敏感性的化合物处理抗生素来杀死具有非遗传抗生素抗性的微生物的方法; 涉及包含该化合物的抗生素抗性抑制化合物; 涉及包含该化合物作为有效成分的微生物感染性疾病的预防或治疗用药物组合物。 本发明的化合物抑制了当施用于各种抗生素时显示的非遗传性抗生素抗性，以防止由此引起的继发性感染并有效地预防或治疗使用抗生素的微生物感染性疾病。
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Patent Agency Ranking
公开(公告)号：KR1020130041613A
公开(公告)日：2013-04-25
申请号：KR1020110105985
申请日：2011-10-17
Applicant: 성균관대학교산학협력단
IPC: A61K31/497 , A61K31/495 , A61P31/00
CPC classification number: A61K31/495 , A61K31/345 , A61K31/496 , Y02A50/475 , Y02A50/483
Abstract: PURPOSE: A non-inherited antibiotic resistance inhibitor and a use thereof are provided to induce apoptosis of a microbe with non-inherited antibiotic resistance. CONSTITUTION: A method for inducing apoptosis of a microbe with non-inherited antibiotic resistance comprises a step of treating the microbe with non-inherited antibiotic resistance using antibiotics and a compound with antibiotic sensitivity, which is selected from the group consisting of 4-(4-(3-chlorophenyl)piperazin-1-yl)piperidin-3-yl 2-naphthoate, 3-(4-(4-methoxyphenyl)piperazin-1-yl)piperidin-4-yl biphenyl-4-carboxylate, (E)-2-nitro-5-styrylfuran, 1-(3-(bis(4-fluorophenyl)methoxy)phenyl)piperazine, a derivative thereof, and a combination thereof. The antibiotic is selected from the group consisting of beta-lactam antibiotics, tetracycline antibiotics, quinolone antibiotics, amino glycoside antibiotics, glycopeptides antibiotics, sulfonamide antibiotics, and a combination thereof.
Abstract translation: 目的：提供非遗传性抗生素抗性抑制剂及其用途，以诱导具有非遗传抗生素抗性的微生物细胞凋亡。 构成：用非导电抗生素抗性诱导微生物细胞凋亡的方法包括使用抗生素和具有抗生素敏感性的化合物治疗具有非遗传抗生素抗性的微生物的步骤，其选自4-（4 - （3-氯苯基）哌嗪-1-基）哌啶-3-基2-萘甲酸酯，3-（4-（4-甲氧基苯基）哌嗪-1-基）哌啶-4-基联苯-4-羧酸乙酯（E ）-2-硝基-5-苯乙烯基呋喃，1-（3-（双（4-氟苯基）甲氧基）苯基）哌嗪及其衍生物及其组合。 抗生素选自β-内酰胺抗生素，四环素抗生素，喹诺酮抗生素，氨基糖苷抗生素，糖肽抗生素，磺胺类抗生素及其组合。
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公开(公告)号：KR1020130036782A
公开(公告)日：2013-04-15
申请号：KR1020110100700
申请日：2011-10-04
Applicant: 성균관대학교산학협력단
IPC: A61K47/48 , A61K9/127 , A61K31/352 , A61K9/10
CPC classification number: A61K47/543 , A61K8/498 , A61K31/352 , A61K47/6911 , A61K2121/00 , A61Q19/08
Abstract: PURPOSE: A myricetin-liposome complex and a manufacturing method thereof are provided to use the complex for the development of various skin wrinkle enhancing cosmetics including myricetin. CONSTITUTION: A myricetin-liposome complex manufacturing method comprises the following steps: a step of obtaining suspension by applying myricetin and lipid to water; a step of forming liposome with collected myricetin by repeating a freezing and melting process of the suspension; and a step of collecting liposome encapsulated with formed myricetin.
Abstract translation: 目的：提供一种杨梅素 - 脂质体复合物及其制造方法，以使用该复合物用于开发包括杨梅素的各种皮肤皱纹增强化妆品。 构成：杨梅素 - 脂质体复合物制造方法包括以下步骤：通过将黄芪素和脂质施用于水得到悬浮液的步骤; 通过重复悬浮液的冷冻和熔融过程形成具有收集的杨梅素的脂质体的步骤; 并收集用形成的杨梅素包裹的脂质体的步骤。
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公开(公告)号：KR1020120105403A
公开(公告)日：2012-09-25
申请号：KR1020120100118
申请日：2012-09-10
Applicant: 성균관대학교산학협력단
Abstract: PURPOSE: A composition containing plant extract for suppressing granule secretion of mast cells is provided to effectively prevent and treat allergic diseases and to be used in a food composition and cosmetic composition. CONSTITUTION: A composition for preventing or treating allergic diseases contains Salix koreensis extract as an active ingredient. The extract is isolated from Salix koreensis stems using methanol. A method for preparing Corydalis speciosa Maxim. extract comprises: a step of pulverizing Salix koreensis; a step of extracting pulverized Salix koreensis with water, organic solvent, or a mixture solvent thereof and drying; and a step of dissolving the dried material with water, organic solvent, or a mixture thereof.
Abstract translation: 目的：提供含有用于抑制肥大细胞的颗粒分泌的植物提取物的组合物，以有效预防和治疗过敏性疾病并用于食品组合物和化妆品组合物中。 构成：用于预防或治疗过敏性疾病的组合物含有柳枝稷提取物作为活性成分。 提取物使用甲醇从柳枝稷茎中分离出来。 一种制备延胡索种子的方法。 提取物包括：粉碎柳柳的步骤; 用水，有机溶剂或其混合溶剂提取粉碎的柳叶柳的步骤并干燥; 以及用水，有机溶剂或其混合物将干燥的材料溶解的步骤。
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公开(公告)号：KR1020120003317A
公开(公告)日：2012-01-10
申请号：KR1020100064099
申请日：2010-07-02
Applicant: 성균관대학교산학협력단
CPC classification number: A61K36/52 , A61K36/13 , A61K36/28 , A61K36/344 , A61K36/35 , A61K36/48 , A61K36/505 , A61K36/73 , A61K36/76 , A61K2300/00
Abstract: PURPOSE: A composition containing plant extract for suppressing degranulation of mast cells is provided to prevent and treat allergic diseases. CONSTITUTION: A composition for suppressing degranulation of mast cells contains Larix leptolepis, Maackia amurensis, Corydalis speciosa, Agrimonia pilosa, Codonopsis pilosula, Salix koreensis, Viburnum wrightii, Platycarya strobilacea, or Salix graciliglans. The extract is isolated from whole plant and leaves using methanol.
Abstract translation: 目的：提供含有用于抑制肥大细胞脱粒的植物提取物的组合物，用于预防和治疗过敏性疾病。 构成：用于抑制肥大细胞脱粒的组合物含有Larix leptolepis，Maackia amurensis，Corydalis speciosa，Agrimonia pilosa，Codonopsis pilosula，Salix koreensis，Viburnum wrightii，Platycarya strobilacea或Salix graciliglans。 提取物从全株分离，用甲醇离心。
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公开(公告)号：KR100901078B1
公开(公告)日：2009-06-03
申请号：KR1020070106592
申请日：2007-10-23
Applicant: 성균관대학교산학협력단
Abstract: 본 발명은 호랑버들, 오미자, 황근, 부들, 싸리, 애기부들, 큰꿩의 비름, 진달래, 쪽, 마가목, 감나무, 동백나무, 생강나무, 굴피나무, 딱지꽃, 밤나무, 말오줌때, 서어나무, 료양화, Negesvari, Raj briksha, Dhayaro, 월계화 및 매괴화의 꽃 추출물에 관한 것이다. 본 발명에 따른 꽃 추출물은 SNARE 복합체의 형성을 저해하여 신경전달물질 배출을 조절하고, BoNT(Botulinum neurotoxin)보다 저렴하게 원료를 제공할 수 있으며, 천연 소재이므로 소비자에게 친숙한 접근이 가능하여 산업적으로 매우 유용하다.
SNARE (Soluble N-ethylmaleimide-sensitive factor attachment protein receptor) 복합체, 신경전달물질, 추출물, 보톡스(BoNT)Abstract translation: 本发明黄花柳，五味子，hwanggeun，零部件，萩，香蒲，keunkkwong，杜鹃花，侧面，山灰，柿子树，山茶花，生姜，木材，化香，黑星病花，栗子，马小便时，鹅耳枥树苋菜， Negesvari，Raj briksha，Dhayaro，Laurelia和Mastiflora。 根据本发明的花提取物是抑制SNARE复合控制神经递质放电的形成，并能廉价地提供的原料比的BoNT（肉毒杆菌神经毒素），天然材料，因为它是为消费者熟悉的访问工业上非常 这很有用。
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