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公开(公告)号：KR1020000051076A
公开(公告)日：2000-08-16
申请号：KR1019990001314
申请日：1999-01-18
Applicant: 한국과학기술연구원
IPC: C07D207/00
Abstract: PURPOSE: Rachlopride derivative attached with an N2S2 ligand useful as imaging compound for a dopamin D2 acceptor and preparing process thereof are provided which label a technetium having the radiochemically optimum physical conditions. CONSTITUTION: A rachlopride derivative represented by the formula (1) is that an N2S2 ligand is introduced into rachlopride to introduce the technetium to the raclopride for the attachment of technetium. The compound has the advantage of labeling a technetium having the optimum physical conditions such as manufacturing easiness, half-life period, radioactive strength and purchase easiness. Also described is a process for preparing the rachlopride.
Abstract translation: 目的：提供与用作多巴胺D2受体的成像化合物的N2S2配体连接的Rachlopride衍生物及其制备方法，其标记具有放射化学最佳物理条件的锝。 构成：由式（1）表示的rachlopride衍生物是将N 2 S 2配体引入rachlopride以将锝引入到raclopride中以连接锝。 该化合物具有标记具有制造容易性，半衰期，放射性强度和购买容易性等最佳物理条件的锝的优点。 还描述了制备rachlopride的方法。
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公开(公告)号：KR1020000051066A
公开(公告)日：2000-08-16
申请号：KR1019990001304
申请日：1999-01-18
Applicant: 한국과학기술연구원
IPC: C07D487/00
Abstract: PURPOSE: Flumazenil derivatives containing a N2S2 ligand and preparing process thereof are provided which are expected to be useful for imaging benzodiazapine CONSTITUTION: A flumazenil derivatives represented by the formula (1), 2-methyl-1-({2-methyl-2-£(2-methyl-2-sulfanylpropyl)amino|propane-2-thiol, 8-fluoro-3-(hydroxymethyl)-5-methyl-4H-benzo£f|imidazole£1,5-al|1,4-diazaperhydroepine- 6-one are prepared. New compound which is capable of being used as a ligand of technetium, being inexpensive and convenient to handle and having appropriate half-life period is provided by this process when a benzodiazepin acceptor is imaged.
Abstract translation: 目的：提供含有N2S2配体的氟马西尼衍生物及其制备方法，其可用于成像苯并二氮萘成分：由式（1）表示的氟马西尼衍生物，2-甲基-1 - （{2-甲基-2- （2-甲基-2-硫烷基丙基）氨基|丙烷-2-硫醇，8-氟-3-（羟甲基）-5-甲基-4H-苯并咪唑1,2,5-三 当苯并二氮杂受体成像时，通过该方法提供能够用作锝配体的新化合物，其便宜且方便处理并具有适当的半衰期。
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公开(公告)号：KR1019990070091A
公开(公告)日：1999-09-06
申请号：KR1019980004741
申请日：1998-02-17
Applicant: 한국과학기술연구원
IPC: B01D71/02
Abstract: 본 발명은 열경화성 수지가 첨가된 무기물 소결 여과재 및 그 제조방법에 관한 것으로, 제올라이트, 백토 등의 무기물 미립자와 미세분말 형태의 열경화성 수지를 균일하게 혼합하여 가열, 가압, 경화에 의해 다공성 구조로 성형하여 이루어진 것을 특징으로 하는 것으로, 다양한 용도로 사용가능하면서도 여과능력 및 기계적 물성이 우수하고, 저렴한 비용으로 용이하게 제조할 수 있는 것이다.
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公开(公告)号：KR101146559B1
公开(公告)日：2012-05-25
申请号：KR1020100046553
申请日：2010-05-18
Applicant: 한국과학기술연구원
IPC: G07D7/12 , G01N21/3563 , G01N21/88 , G01J3/28
Abstract: 분광법을 이용한 인주 및 서명 감식 방법을 개시한다. 본 발명의 일 실시예에 따른 인주 감식 방법은, 인영(印影)의 배경에 대하여 분광 스펙트럼을 측정하는 단계와, 날인된 인영 부분에 대하여 분광 스펙트럼을 측정하는 단계와, 인영 부분의 분광 스펙트럼으로부터 배경의 분광 스펙트럼을 제거하여 인주(印朱)의 분광 스펙트럼을 구하는 단계와, 인주의 분광 스펙트럼에서 검색 키로 사용할 특징을 선택하는 단계와, 인주 샘플 스펙트럼 데이터베이스에서 검색 키에 대하여 미리 정해진 값 이상의 동등성 조건을 만족하는 인주 샘플 스펙트럼을 검색하는 단계 및 검색된 결과에 기반하여 동등성 조건을 만족하는 인주 샘플의 발견 여부 및 발견된 인주 샘플의 출처 정보를 출력하는 단계를 포함한다.
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公开(公告)号：KR100367575B1
公开(公告)日：2003-01-10
申请号：KR1020000041597
申请日：2000-07-20
Applicant: 한국과학기술연구원
IPC: A01G31/00
Abstract: 콩나물류의 부패가 일어나지 않아 위생적이고 생산성이 높음과 아울러 폐수에 의한 환경오염문제가 없는 콩나물류 재배방법 및 그 장치에 관한 것으로, 콩나물 재배부로부터 배출된 오염물질 내지 불순물이 포함된 재배수에 응집제를 투입하여 오염물질 내지 불순물을 응집시켜 슬러지가 되게 하는 단계와, 응집된 슬러지를 포함한 재배수를 DAF처리하여 슬러지를 제거하는 단계와, 슬러지가 제거된 깨끗한 재배수를 상기 콩나물 재배부로 재공급하는 단계를 구비하는 것을 특징으로 하는 콩나물류 재배방법과 그를 실현하기 위한 장치가 제공된다.
Abstract translation: 目的：提供一种豆芽的培育方法和装置，该方法和装置能够防止豆芽在处理后通过循环用水而防止豆腐腐烂，该方法和装置可防止环境污染，提高生产率并减少用水量。 组成：在含有从豆芽培养部分（1）排出的污染物或杂质的废水中，在溶解气浮（DAF）罐（3）中引入混凝剂以凝结污染物或杂质，从污泥 - 通过DAF处理废水和处理后的含水废水，用消毒剂对废水进行灭菌并向其中倒入无机营养素后，再将其供给豆芽的培养部分。 凝固剂和防腐剂的浓度分别为1至20ppm和0.1至10ppm。
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Patent Agency Ranking
公开(公告)号：KR1020020087570A
公开(公告)日：2002-11-23
申请号：KR1020010026194
申请日：2001-05-14
Applicant: 한국과학기술연구원 , 주식회사 엔에스케이텍
IPC: A61K36/068 , A61P3/10
Abstract: PURPOSE: A method for cultivation of Paecilomyces Japonica using a silkworm without a pupa as a host and a freeze drying method is provided. Therefore, a product having an excellent therapeutic effect on diabetic is produced with high productivity without causing the depletion of nutrients. CONSTITUTION: In the process for artificial cultivation of Paecilomyces Japonica, a 5 day old silkworm as a host is subjected to sterilization using chlorine dioxide water with a concentration of 1 to 5ppm without using heat treatment, a compound selected from the group consisting of silk amino acid, sugar and a mixture thereof is added to a medium for cultivation thereof, and then the silkworm is freeze dried and killed through an electric shock method.
Abstract translation: 目的：提供使用没有蛹作为宿主的蚕培养拟青藓的方法和冷冻干燥方法。 因此，以高生产率生产对糖尿病具有优异治疗效果的产品，而不会导致营养物质的消耗。 构成：在人造培养拟青藓的过程中，将5日龄的蚕作为宿主，使用浓度为1〜5ppm的二氧化氯水进行灭菌，不用热处理，选自丝氨基 酸，糖及其混合物加入到培养基中，然后通过电击法将蚕冷冻干燥灭活。
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公开(公告)号：KR1020020005863A
公开(公告)日：2002-01-18
申请号：KR1020000039341
申请日：2000-07-10
Applicant: 한국과학기술연구원
IPC: C01B11/02
CPC classification number: C01B11/024 , B01J19/006 , B01J19/1893 , B01J2219/00164 , B01J2219/00177 , B01J2219/00763
Abstract: PURPOSE: A method for preparing chlorine dioxide in high yield is accomplished by proper adjustment of the supply ratio of sodium chlorite and chlorine, by which hydrogen-ion concentration condition is optimized. The chlorine dioxide, when applied to cooling water, showed excellent bactericidal effect against Legionella pneumophila when applied to cooling water. In addition, chlorine dioxide has proven to be effective in eliminating alien algae in cultivating lava. CONSTITUTION: In the generation of chlorine dioxide using sodium chlorite and chlorine, by using a flowmeter and a chemical pump, Cl2 supply rate and NaClO2 supply rate are controlled to adjust pH in the range 1.9 to 2.0. For the smooth dissolving of chlorine gas into sodium chlorite solution, chlorine gas is supplied through glass wool(7), and a baffle(8) is installed to be perpendicular to a sodium chlorite/chlorine inlet. The baffle plays role in converting laminar flow to turbulent flow within short time.
Abstract translation: 目的：通过适当调整亚氯酸钠和氯的供应比，通过优化氢离子浓度条件来实现高产量制备二氧化氯的方法。 当应用于冷却水时，二氧化氯在用于冷却水时对嗜肺军团病菌显示出极好的杀菌作用。 此外，二氧化氯已被证明有效地消除培养熔岩中的外来藻类。 构成：使用亚氯酸钠和氯生成二氧化氯，通过使用流量计和化学泵，控制Cl2供应速率和NaClO2供应速率，调节pH在1.9至2.0。 为了将氯气平滑溶解在亚氯酸钠溶液中，氯气通过玻璃棉（7）供应，挡板（8）安装成与亚氯酸钠/氯气入口垂直。 挡板在短时间内将层流转化为湍流的作用。
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公开(公告)号：KR1020000051067A
公开(公告)日：2000-08-16
申请号：KR1019990001305
申请日：1999-01-18
Applicant: 한국과학기술연구원
IPC: C07D473/00
Abstract: PURPOSE: A purine compound having a substitutent group at the C-8 position is provided which is expected to be useful as an inhibitor of cyclin-dependent kinase. CONSTITUTION: A purine compound represented by the formula 1 having a substitutent group at the C-8 position is prepared, Thus, urea and ethylisocyanoacetate are subjected to heating reflux in the presence of a base to give a compound of formula 2, which is subjected to heating reflux after nitration and treated with sodium hydrosulfide to give a compound of formula 3, which is subjected to reaction continuously to give the title compound. In formula, R1 is methyl or phenyl; R2 is ethanolamine, or 2-amino-3-methyl-1-butanol.
Abstract translation: 目的：提供在C-8位置具有取代基的嘌呤化合物，其预期可用作细胞周期蛋白依赖性激酶的抑制剂。 构成：制备在C-8位具有取代基的式1表示的嘌呤化合物。因此，在碱的存在下，将脲和乙基异氰酸乙酯进行加热回流，得到式2的化合物， 硝化后加热回流并用氢硫化钠处理，得到式3的化合物，其连续进行反应，得到标题化合物。 在式中，R 1是甲基或苯基; R2是乙醇胺，或2-氨基-3-甲基-1-丁醇。
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公开(公告)号：KR1020000051061A
公开(公告)日：2000-08-16
申请号：KR1019990001299
申请日：1999-01-18
Applicant: 한국과학기술연구원
IPC: C07D477/00 , C07D487/04
Abstract: PURPOSE: A thiol derivative having a novel bicyclic and 1-beta-methyl-carbaphenem having them as a substituent group at its 2-position are provided which are useful for resolving the reduction of activity of conventional carbaphenem by DHP-1. CONSTITUTION: A bicyclic thiol derivative of formula (1) and 1-beta-methyl-2-thio based carbaphenem of formula (2) having two methyl groups at its 2-position are described. In formula, R denotes H, C1-6 lower alkyl, C1-6 lower cycloalkyl, aryl, benzyl, or amino group-substituted C1-6 lower alkyl. Preferably the lower alkyl is methyl, ethyl, propyl, cyclopropylmethyl and the amino group-substituted C1-6 lower alkyl is amino ethyl.
Abstract translation: 目的：提供一种具有新的双环和1-β-甲基 - 碳青霉烯在其2-位具有取代基的硫醇衍生物，可用于解决通过DHP-1降低常规碳青霉烯酮的活性。 描述：描述了在其2位具有两个甲基的式（1）的双环硫醇衍生物和式（2）的1-β-甲基-2-硫基碳代苯并芬酮。 在式中，R表示H，C 1-6低级烷基，C 1-6低级环烷基，芳基，苄基或氨基取代的C 1-6低级烷基。 优选地，低级烷基是甲基，乙基，丙基，环丙基甲基，氨基取代的C 1-6低级烷基是氨基乙基。
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