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公开(公告)号：CA2249779A1
公开(公告)日：1998-03-19
申请号：CA2249779
申请日：1997-08-28
Applicant: ABBOTT LAB
Inventor： FRITCHIE PATRICK P , DUNN CHADWICK M , GRANDONE CASS J , SLESZYNSKI NEAL T , MITCHELL JAMES E , BARNES GRADY III , BUTTON RICHARD D , MURRAY ADRIAN J , EAST RICHARD C JR , MURRAY DAVID W , ARNQUIST DAVID C , MCCOY JIMMY D , GALITZ CHARLES M , GRAY ROBERT C , GARDNER GREGORY E , TOTH JULIUS J , HOLEN JAMES T , LUOMA ROBERT P II , RAMSEY JACK F
Abstract: A method of constructing at least a first process lane and a second process lane, both for determining an item of interest in a sample; the method includes the steps of: (a) defining an effective length representing a total traveled distance of a container, in which the item of interest in the sample is determined, along a process lane where a process step comprises a process for determining the item of interest in the sample is performed; (b) constructing the first process lane to have a first physical length and the effective length; and (c) constructing the second process lane to have a second physical length different from the first physical length and the effective length; the sample is in particular a body fluid, for example, blood, on which tests are to be carried out for a component in the fluid, as part of the determination of the health of a person from whom the sample is obtained.
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公开(公告)号：ES2044997T3
公开(公告)日：1994-01-16
申请号：ES88105532
申请日：1988-04-07
Applicant: ABBOTT LAB
Inventor： GRANDONE CASS J
IPC: G01N33/48 , B01L3/00 , G01N21/03 , G01N33/543 , G01N35/04
Abstract: A plurality of disposable cartridges (20), each having a plurality of wells including at least one assay reaction well, are loaded in a plurality of openings arranged radially around a rack (30) of a carousel (10). Securing of the cartridges in a predetermined orientation and position in said openings is ensured by means of alignment and securing means on the cartridges and corresponding means on the rack. A locking hub (40) with tangs is mounted on the rack and is rotated to cause the tangs to contact locator tabs on each cartridge to force locator nubs on each of the cartridges radially into corresponding notches on the rack, and to accurately wedge the cartridges against the outer periphery of the rack. The carousel indexes for positioning the cartridges under a variety of stations, one of which generally contains an optical reader such as a fluorometer.
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公开(公告)号：CA2069545A1
公开(公告)日：1992-12-04
申请号：CA2069545
申请日：1992-05-26
Applicant: ABBOTT LAB
Inventor： GRANDONE CASS J , HERCHENBACH STEPHEN L , TYRANSKI JAMES T
IPC: B01J4/02 , B01L3/14 , B65D47/08 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , B65D41/20 , B01L3/00 , B65D51/24 , B65D41/28
Abstract: REAGENT BOTTLE AND CAP A reagent bottle and cap assembly includes a bottle which may be positioned in current apparatus in such a manner that the removal of fluids is maximized. The cap has a flip-top with a live hinge and live over-center spring for holding the cap in an open position and includes a conical core which is in communication with a wiper blade for breaking the meniscus or fluid seal between the core and the neck to enhance the flow of fluids which have collected on the cap back into the bottle for minimizing evaporation.
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公开(公告)号：AU1474488A
公开(公告)日：1988-10-27
申请号：AU1474488
申请日：1988-04-19
Applicant: ABBOTT LAB
Inventor： GRANDONE CASS J
Abstract: A plurality of disposable cartridges (20), each having a plurality of wells including at least one assay reaction well, are loaded in a plurality of openings arranged radially around a rack (30) of a carousel (10). Securing of the cartridges in a predetermined orientation and position in said openings is ensured by means of alignment and securing means on the cartridges and corresponding means on the rack. A locking hub (40) with tangs is mounted on the rack and is rotated to cause the tangs to contact locator tabs on each cartridge to force locator nubs on each of the cartridges radially into corresponding notches on the rack, and to accurately wedge the cartridges against the outer periphery of the rack. The carousel indexes for positioning the cartridges under a variety of stations, one of which generally contains an optical reader such as a fluorometer.
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公开(公告)号：AT313082T
公开(公告)日：2005-12-15
申请号：AT97116256
申请日：1997-09-18
Applicant: ABBOTT LAB
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Patent Agency Ranking
公开(公告)号：CA2214125C
公开(公告)日：2003-08-05
申请号：CA2214125
申请日：1997-08-28
Applicant: ABBOTT LAB
Inventor： GRANDONE CASS J , GRAY ROBERT C , TOTH JULIUS J , RAMSEY JACK F , MURRAY DAVID W , FRITCHIE PATRICK P , MCCOY JIMMY D , SLESZYNSKI NEAL T , MURRAY ADRIAN J , GALITZ CHARLES M , ARNQUIST DAVID C , MITCHELL JAMES E , BARNES GRADY III , BUTTON RICHARD D , GARDNER GREGORY E , EAST RICHARD C JR , HOLEN JAMES T , DUNN CHADWICK M , LUOMA ROBERT P II
IPC: G01N35/02
Abstract: The embodiments disclosed relate to determination of an item of interest in a sample. One embodiment relates to a structure which comprises a process path. The process path comprises a process lane including a process step performance lane where a process step is performed, and a process step avoidance lane where the process step is avoided. A first prime mover is operatively connected with the process path for moving a container holding the sample along the process path. A first pipetting system is operatively associated with the process path for introducing the sample to the container. A second pipetting system is operatively associated with the process path for introducing a reagent to the container. A device is operatively connected with the process path and is selectively engagable with the container for mixing the sample and the reagent in the container. A second prime mover is operatively connected with the process path for selectively positioning the container in a selected one of the process step performance lane and the process step avoidance lane. A reader is operatively connected with the process path for determining the item of interest in the sample based upon a reaction between the sample and the reagent; the embodiments disclosed also related to determination of an item of interestin a sample. In one method, a process path comprising a process lane including a process step performance lane where a process step is performed, and a process step avoidance lane where the process step is avoided is provided. A container holding the sample is moved along the process path. The sample is introduced to the container. A reagent is introduced to the container. The sample and the reagent are mixed in the container. The container is selectively positioned in a selected one of the process step performance lane and the process step avoidance lane. The item of interest in the sample is determined based upon a reaction between the sample and the reagent; embodiments also described herein provide methods of performing a process for determining an item of interest in a sample. In one embodiment, a container for holding the sample is accepted in a process lane where a process step is selectively automatically performed on the sample in the container. The process step is selectively automatically performed on the sample in the container. An effective length of the process lane is maintained constant while a physical length of the process lane is selectively varied.
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公开(公告)号：CA2249779C
公开(公告)日：2003-02-18
申请号：CA2249779
申请日：1997-08-28
Applicant: ABBOTT LAB
Inventor： MCCOY JIMMY D , BUTTON RICHARD D , EAST RICHARD C JR , DUNN CHADWICK M , MITCHELL JAMES E , GRANDONE CASS J , GARDNER GREGORY E , MURRAY ADRIAN J , GRAY ROBERT C , ARNQUIST DAVID C , LUOMA ROBERT P II , MURRAY DAVID W , FRITCHIE PATRICK P , RAMSEY JACK F , GALITZ CHARLES M , BARNES GRADY III , HOLEN JAMES T , TOTH JULIUS J , SLESZYNSKI NEAL T
Abstract: A method of constructing at least a first process lane and a second process lane, both for determining an item of interest in a sample; the method includes the steps of: (a) defining an effective length representing a total traveled distance of a container, in which the item of interest in the sample is determined, along a process lane where a process for determining the item of interest in the sample is performed; (b) constructing the first process lanefor determining an item of interest in a sample, said first process lane having a first physical length, said first physical length being less than the effective lengthof said first process lane; and (c) constructing the second process lane for determining an item of interest in a sample, said second process lane having a second physical length different from the first physical length, said second physical length being less than the effective length of said second process lane; the sample is in particular a body fluid, for example, blood, on which tests are to be carried out for a component in the fluid, as part of the determination of the health of a person from whom the sample is obtained.
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公开(公告)号：AT213839T
公开(公告)日：2002-03-15
申请号：AT97114411
申请日：1997-08-20
Applicant: ABBOTT LAB
Inventor： ARNQUIST DAVID C , BARNES GRADY III , BUTTON RICHARD D , DUNN CHADWICK M , EAST RICHARD C JR , FRITCHIE PATRICK P , GALITZ CHARLES M , GRANDONE CASS J , GARDNER GREGORY E , GRAY ROBERT C , HOLEN JAMES T , LUOMA ROBERT P II , MCCORY JIMMY D , MITCHELL JAMES E , MURRAY ADRIAN JOHN , MURRAY DAVID W , RAMSEY JACK F , SLESZYNSKI NEAL T , TOTH JULIUS J
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公开(公告)号：DE69214013D1
公开(公告)日：1996-10-31
申请号：DE69214013
申请日：1992-05-27
Applicant: ABBOTT LAB
Inventor： ZUCK GARY LEE , TYRANSKI JAMES L , HERCHENBACH STEPHEN L , NELSON ROBERT J , GRANDONE CASS J
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公开(公告)号：DE3882783T2
公开(公告)日：1993-11-11
申请号：DE3882783
申请日：1988-04-07
Applicant: ABBOTT LAB
Inventor： GRANDONE CASS J
IPC: G01N33/48 , B01L3/00 , G01N21/03 , G01N33/543 , G01N35/04
Abstract: A plurality of disposable cartridges (20), each having a plurality of wells including at least one assay reaction well, are loaded in a plurality of openings arranged radially around a rack (30) of a carousel (10). Securing of the cartridges in a predetermined orientation and position in said openings is ensured by means of alignment and securing means on the cartridges and corresponding means on the rack. A locking hub (40) with tangs is mounted on the rack and is rotated to cause the tangs to contact locator tabs on each cartridge to force locator nubs on each of the cartridges radially into corresponding notches on the rack, and to accurately wedge the cartridges against the outer periphery of the rack. The carousel indexes for positioning the cartridges under a variety of stations, one of which generally contains an optical reader such as a fluorometer.
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