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公开(公告)号:JPH10260189A
公开(公告)日:1998-09-29
申请号:JP25559697
申请日:1997-09-19
Applicant: ABBOTT LAB
Inventor: ARNQUIST DAVID C , BARNES GRADY III , BUTTON RICHARD D , DUNN CHADWICK M , EAST RICHARD C JR , FRITCHIE PATRICK P , GALITZ CHARLES M , GARDNER GREGORY E , GRANDONE CASS J , GRAY ROBERT C , HOLEN JAMES T , LUOMA ROBERT P II , MCCOY JIMMY D , MITCHELL JAMES E , ADRIAN J MURRY , MURRAY DAVID W , RAMSEY JACK F , SLESZYNSKI NEAL T , TOTH JULIUS J
Abstract: PROBLEM TO BE SOLVED: To provide a method to produce a structure for the execution of the determination of items of concern in a sample. SOLUTION: By one method, the effective length of movement of a container 15 holding a sample at a process lane 28 which selectively and automatically performs process steps on a sample in the container 15 is determined. The process lane 28 is produced so as to correspond to at least one of predetermined throughput and predetermined physical size. Elements are arranged along the process lane 28 so that the container 15 moves the effective length during the execution of the determination of items of concern.
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公开(公告)号:JPH11194133A
公开(公告)日:1999-07-21
申请号:JP28665298
申请日:1998-10-08
Applicant: ABBOTT LAB
Inventor: ARNQUIST DAVID C , BARNES GRADY III , BUTTON RICHARD D , DUNN CHADWICK M , EAST RICHARD C JR , FRITCHIE PATRICK P , GALITZ CHARLES M , GRANDONE CASS J , GARDNER GREGORY E , GRAY ROBERT C , HOLEN JAMES T , LUOMA ROBERT P II , MCCOY JIMMY D , MITCHELL JAMES E , MURRAY ADRIAN JOHN , MURRAY DAVID W , RAMSEY JACK F , SLESZYNSKI NEAL T , TOTH JULIUS J
IPC: G01N33/483 , G01N33/49 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04
Abstract: PROBLEM TO BE SOLVED: To provide a method in which an interested item in a sample is decided. SOLUTION: A method provides a process route provided with a process lane 28 in which a process-step execution lane 62 used to execute a process step and a process-step prevention lane 64 used to prevent the process step are contained. A container which holds a sample is moved along the process route. The sample is introduced into the container. A reagent is introduced into the container. The sample and the reagent are mixed inside the container. The container is arranged selectively in one selected out of the process-step execution lane 62 and the process-step prevention lane 64. An interested item in the sample is decided on the basis of the reaction of the sample with the reagent.
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公开(公告)号:JPH10282113A
公开(公告)日:1998-10-23
申请号:JP10300698
申请日:1998-04-14
Applicant: ABBOTT LAB
Inventor: ARNQUIST DAVID C , BARNES GRADY III , BUTTON RICHARD D , DUNN CHADWICK M , EAST RICHARD C JR , FRITCHIE PATRICK P , GALITZ CHARLES M , GARDNER GREGORY E , GRANDONE CASS J , GRAY ROBERT C , HOLEN JAMES T , LUOMA ROBERT P II , MCCOY JIMMY D , MITCHELL JAMES E , ADRIAN J MURRY , MURRAY DAVID W , RAMSEY JACK F , SLESZYNSKI NEAL T , TOTH JULIUS J
IPC: G01N33/483 , G01N33/49 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04
Abstract: PROBLEM TO BE SOLVED: To provide a method for forming a structure for deciding an item of concern contained in a sample. SOLUTION: In a process lane 28 in which process steps are selectively and automatically performed on a sample contained in a container 15, the effective moving length of the container 15 containing the sample is decided. The lane 28 is formed so that the lane 28 may become suitable to at least either one of a predetermined throughput and a predetermined physical dimension. At the time of deciding an item of concern, elements are arranged along the lane 28 so that the container 15 may move by the effective length.
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公开(公告)号:EP0588931A4
公开(公告)日:1994-06-22
申请号:EP92913497
申请日:1992-06-11
Applicant: ABBOTT LAB
Inventor: CHOW HERBERT S , WILSON THOMAS J , WROBLEWSKI MIECZYSLAW , KOTLARIK JOHN J , ALSBERG KEITH D , MCCOY JIMMY D , LADD JIMMY L , CORBETT KEVIN M
IPC: G01N21/17 , B01L3/00 , B01L3/02 , G01N15/14 , G01N21/82 , G01N33/48 , G01N33/483 , G01N33/543 , G01N33/80 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , G02B7/28 , G06T1/00 , G01N21/01
CPC classification number: G01N35/109 , B01L3/0262 , B01L3/5085 , G01N15/1468 , G01N21/82 , G01N35/0095 , G01N35/0098 , G01N35/028 , G01N35/1004 , G01N2035/042 , G01N2035/0425 , G01N2035/0491 , G01N2035/1018 , G01N2035/1025 , G01N2035/1034 , G01N2201/0446 , G01N2201/0461 , G01N2201/0492 , G02B7/28 , Y10T137/7306 , Y10T436/115831
Abstract: An apparatus is provided for moving a reaction cartridge (10) to different processing areas (36, 38, 42) of the apparatus. Robots (34, 40) for moving the reaction cartridge to the various areas (30, 32, 36, 38, 42, 46) of the apparatus. An image forming device (42) is provided to detect images which indicate whether specific reactions have occurred in reaction wells (16) of the reaction cartridge (10). The apparatus also includes a mechanism (36) for aspirating and dispensing liquids which includes a liquid level detecting mechanism (70, 72, 74, 76, 78, 80, 82, 84). The device further includes a microprocessor and logic (44) for controlling the apparatus operation and analyzing the information received from the image forming device (42) to generate a visual indication of assay results.
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公开(公告)号:EP0588967A4
公开(公告)日:1994-06-22
申请号:EP92914524
申请日:1992-06-12
Applicant: ABBOTT LAB
Inventor: CHOW HERBERT S , WILSON THOMAS J , ALSBERG KEITH D , MCCOY JIMMY D , SEBESTA ESWARD E
IPC: G01N21/17 , B01L3/00 , B01L3/02 , G01N15/14 , G01N21/82 , G01N33/48 , G01N33/483 , G01N33/543 , G01N33/80 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , G02B7/28 , G06T1/00 , G01N21/03
CPC classification number: G01N35/109 , B01L3/0262 , B01L3/5085 , G01N15/1468 , G01N21/82 , G01N35/0095 , G01N35/0098 , G01N35/028 , G01N35/1004 , G01N2035/042 , G01N2035/0425 , G01N2035/0491 , G01N2035/1018 , G01N2035/1025 , G01N2035/1034 , G01N2201/0446 , G01N2201/0461 , G01N2201/0492 , G02B7/28 , Y10T137/7306 , Y10T436/115831
Abstract: A reaction cartridge (10) for an automatic analysis apparatus having a plurality of reaction wells (16) having different reagents disposed thereon, at least one sample well (11a, 11b), a well (12) containing magnetically separable particles for binding the sample, a fluorophore containing well (13), and a wash area (15) for washing a probe.
Abstract translation: 提供了一种装置,其包括具有多个反应孔的反应筒,反应孔具有设置在其上的不同试剂,至少一个适于接收样品的孔,含有适于结合样品的颗粒的孔,并具有与样品分离的能力 不结合分离颗粒的细胞和适于结合样品中特定类型的细胞的至少一种荧光团和适于洗涤探针的洗涤区域。 提供图像形成装置以检测指示每个反应孔中是否发生特定反应的图像。 该装置还包括用于分配和抽吸液体的机构,包括用于检测液位的机构。 该装置还包括用于分析从图像检测装置接收的信息并处理信息以生成正在执行的测定结果的视觉指示的逻辑。 提供微处理器以帮助设备的操作以及图像处理。
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公开(公告)号:CA2214125A1
公开(公告)日:1998-03-19
申请号:CA2214125
申请日:1997-08-28
Applicant: ABBOTT LAB
Inventor: BARNES GRADY III , SLESZYNSKI NEAL T , RAMSEY JACK F , MURRAY ADRIAN J , HOLEN JAMES T , GRANDONE CASS J , GARDNER GREGORY E , MURRAY DAVID W , GALITZ CHARLES M , EAST RICHARD C JR , FRITCHIE PATRICK P , BUTTON RICHARD D , MITCHELL JAMES E , GRAY ROBERT C , TOTH JULIUS J , ARNQUIST DAVID C , MCCOY JIMMY D , DUNN CHADWICK M , LUOMA ROBERT P II
IPC: G01N35/02
Abstract: The embodiments disclosed relate to determination of an item of interest in a sample. One embodiment relates to a structure which comprises a process path. The process path comprises a process lane including a process step performance lane where a process step is performed, and a process step avoidance lane where the process step is avoided. A first prime mover is operatively connected with the process path for moving a container holding the sample along the process path. A first pipetting system is operatively associated with the process path for introducing the sample to the container. A second pipetting system is operatively associated with the process path for introducing a reagent to the container. A device is operatively connected with the process path and is selectively engagable with the container for mixing the sample and the reagent in the container. A second prime mover is operatively connected with the process path for selectively positioning the container in a selected one of the process step performance lane and the process step avoidance lane. A reader is operatively connected with the process path for determining the item of interest in the sample based upon a reaction between the sample and the reagent; the embodiments disclosed also related to determination of an item of interestin a sample. In one method, a process path comprising a process lane including a process step performance lane where a process step is performed, and a process step avoidance lane where the process step is avoided is provided. A container holding the sample is moved along the process path. The sample is introduced to the container. A reagent is introduced to the container. The sample and the reagent are mixed in the container. The container is selectively positioned in a selected one of the process step performance lane and the process step avoidance lane. The item of interest in the sample is determined based upon a reaction between the sample and the reagent; embodiments also described herein provide methods of performing a process for determining an item of interest in a sample. In one embodiment, a container for holding the sample is accepted in a process lane where a process step is selectively automatically performed on the sample in the container. The process step is selectively automatically performed on the sample in the container. An effective length of the process lane is maintained constant while a physical length of the process lane is selectively varied.
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公开(公告)号:DE69734863D1
公开(公告)日:2006-01-19
申请号:DE69734863
申请日:1997-09-18
Applicant: ABBOTT LAB
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公开(公告)号:CA2214207A1
公开(公告)日:1998-09-11
申请号:CA2214207
申请日:1997-08-28
Applicant: ABBOTT LAB
Inventor: GRANDONE CASS J , MITCHELL JAMES E , MCCOY JIMMY D , GRAY ROBERT C , SLESZYNSKI NEAL T , MURRAY DAVID W , MURRAY ADRIAN J , RAMSEY JACK F , FRITCHIE PATRICK P , GARDNER GREGORY E , ARNQUIST DAVID C , HOLEN JAMES T , BARNES GRADY III , EAST RICHARD C JR , DUNN CHADWICK M
Abstract: Methods of constructing a structure for determining an item of interest in a sample are provided. According to one method, an effective length of movement of a container (15) for holding the sample in a process lane (28) where a process step is selectively automatically performed on the sample in the container (15) is determined. The process lane (28) is constructed such that the process lane (28) meets at least one of a predetermined throughput and a predetermined physical dimension. Elements are arranged along the process lane (28) such that the container (15) moves the effective length during performance of a determination of an item of interest.
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公开(公告)号:CA2249779A1
公开(公告)日:1998-03-19
申请号:CA2249779
申请日:1997-08-28
Applicant: ABBOTT LAB
Inventor: FRITCHIE PATRICK P , DUNN CHADWICK M , GRANDONE CASS J , SLESZYNSKI NEAL T , MITCHELL JAMES E , BARNES GRADY III , BUTTON RICHARD D , MURRAY ADRIAN J , EAST RICHARD C JR , MURRAY DAVID W , ARNQUIST DAVID C , MCCOY JIMMY D , GALITZ CHARLES M , GRAY ROBERT C , GARDNER GREGORY E , TOTH JULIUS J , HOLEN JAMES T , LUOMA ROBERT P II , RAMSEY JACK F
Abstract: A method of constructing at least a first process lane and a second process lane, both for determining an item of interest in a sample; the method includes the steps of: (a) defining an effective length representing a total traveled distance of a container, in which the item of interest in the sample is determined, along a process lane where a process step comprises a process for determining the item of interest in the sample is performed; (b) constructing the first process lane to have a first physical length and the effective length; and (c) constructing the second process lane to have a second physical length different from the first physical length and the effective length; the sample is in particular a body fluid, for example, blood, on which tests are to be carried out for a component in the fluid, as part of the determination of the health of a person from whom the sample is obtained.
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公开(公告)号:DE69734863T2
公开(公告)日:2006-07-27
申请号:DE69734863
申请日:1997-09-18
Applicant: ABBOTT LAB
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