公开(公告)号：JP2013238607A

公开(公告)日：2013-11-28

申请号：JP2013140346

申请日：2013-07-04

Applicant: Abbott Lab ,  アボット・ラボラトリーズAbbott Laboratories

Inventor： FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  RICHARD W MAHONEY ,  OSCAR F SCHWARTZ

IPC: G01N35/02 ,  G01N35/00 ,  G06K17/00 ,  G06K19/00 ,  G06K19/07

CPC classification number: G01N35/00732 ,  B01L3/545 ,  B01L2300/022 ,  B01L2300/024 ,  G01N2035/00782 ,  G01N2035/00851

Abstract: PROBLEM TO BE SOLVED: To provide a system for automation of an analyzer for laboratory which uses a container and a liquid container used in the system, and a radio recognition (RFID) tag and a radio recognition (RFID) reader to identify contents thereof.SOLUTION: Radio recognition tags 18 adaptive to guidelines of ISO14443 or ISO15693 or ISO18000 are arranged on an object such as a reagent container, a sample container 14, a microplate, etc. Those tags can be read and written through a movable antenna of an RFID reader or a fixed antenna of the RFID reader. The reading from the RFID tags and the writing to the RFID tags are controlled by software.

Abstract translation: 要解决的问题：提供一种使用系统中使用的容器和液体容器的实验室分析仪的自动化系统，以及用于识别其内容的无线电识别（RFID）标签和无线电识别（RFID）读取器。 解决方案：适用于ISO14443或ISO15693或ISO18000准则的无线电识别标签18布置在诸如试剂容器，样品容器14，微板等物体上。这些标签可以通过RFID的可移动天线读取和写入 阅读器或RFID读取器的固定天线。 RFID标签的读取和对RFID标签的写入由软件控制。

公开(公告)号：JPH10260189A

公开(公告)日：1998-09-29

申请号：JP25559697

申请日：1997-09-19

Applicant: ABBOTT LAB

Inventor： ARNQUIST DAVID C ,  BARNES GRADY III ,  BUTTON RICHARD D ,  DUNN CHADWICK M ,  EAST RICHARD C JR ,  FRITCHIE PATRICK P ,  GALITZ CHARLES M ,  GARDNER GREGORY E ,  GRANDONE CASS J ,  GRAY ROBERT C ,  HOLEN JAMES T ,  LUOMA ROBERT P II ,  MCCOY JIMMY D ,  MITCHELL JAMES E ,  ADRIAN J MURRY ,  MURRAY DAVID W ,  RAMSEY JACK F ,  SLESZYNSKI NEAL T ,  TOTH JULIUS J

IPC: G01N35/02 ,  G01N35/00 ,  G01N35/04

Abstract: PROBLEM TO BE SOLVED: To provide a method to produce a structure for the execution of the determination of items of concern in a sample. SOLUTION: By one method, the effective length of movement of a container 15 holding a sample at a process lane 28 which selectively and automatically performs process steps on a sample in the container 15 is determined. The process lane 28 is produced so as to correspond to at least one of predetermined throughput and predetermined physical size. Elements are arranged along the process lane 28 so that the container 15 moves the effective length during the execution of the determination of items of concern.

公开(公告)号：JPH10142232A

公开(公告)日：1998-05-29

申请号：JP25559497

申请日：1997-09-19

Applicant: ABBOTT LAB

Inventor： ARNQUIST DAVID C ,  BARNES GRADY III ,  BUTTON RICHARD D ,  DUNN CHADWICK M ,  EAST RICHARD C JR ,  FRITCHIE PATRICK P ,  GALITZ CHARLES M ,  GARDNER GREGORY E ,  GRANDONE CASS J ,  GRAY ROBERT C ,  HOLEN JAMES T ,  LUOMA ROBERT P II ,  MCCORY JIMMY D ,  MITCHELL JAMES E ,  MURRAY ADRIAN J ,  MURRAY DAVID W ,  RAMSEY JACK F ,  SLESZYNSKI NEAL T ,  TOTH JULIUS J

IPC: G01N33/543 ,  G01N35/04

Abstract: PROBLEM TO BE SOLVED: To constitute a structure for executing a process of determining concerned items in a sample by connecting a prime mover to a process path to move a container, holding the sample, along the process path. SOLUTION: A prime mover 24 is connected to a process path 10 to move a container, holding a sample, along the process path 10, that is, a plurality of teeth are provided at the outer diameter surface of a disc 16 and meshed with a gear driven by the prime mover 24 fitted to a base 14 by a bracket 26. The prime mover 24 and the whole process path 10 are driven being connected to a control device such as a computer for executing appropriate routine or the like. The disc 16 moves corresponding to the motion of the gear driven by the prime mover 24. The base 14 guides the container along the process path 10 in correspondence with the motion of the disc 16. When the disc 16 moves, the container moves from one processing station to another processing station, and concerned items in the sample are determined.

公开(公告)号：JPH11194133A

公开(公告)日：1999-07-21

申请号：JP28665298

申请日：1998-10-08

Applicant: ABBOTT LAB

Inventor： ARNQUIST DAVID C ,  BARNES GRADY III ,  BUTTON RICHARD D ,  DUNN CHADWICK M ,  EAST RICHARD C JR ,  FRITCHIE PATRICK P ,  GALITZ CHARLES M ,  GRANDONE CASS J ,  GARDNER GREGORY E ,  GRAY ROBERT C ,  HOLEN JAMES T ,  LUOMA ROBERT P II ,  MCCOY JIMMY D ,  MITCHELL JAMES E ,  MURRAY ADRIAN JOHN ,  MURRAY DAVID W ,  RAMSEY JACK F ,  SLESZYNSKI NEAL T ,  TOTH JULIUS J

IPC: G01N33/483 ,  G01N33/49 ,  G01N33/543 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04

Abstract: PROBLEM TO BE SOLVED: To provide a method in which an interested item in a sample is decided. SOLUTION: A method provides a process route provided with a process lane 28 in which a process-step execution lane 62 used to execute a process step and a process-step prevention lane 64 used to prevent the process step are contained. A container which holds a sample is moved along the process route. The sample is introduced into the container. A reagent is introduced into the container. The sample and the reagent are mixed inside the container. The container is arranged selectively in one selected out of the process-step execution lane 62 and the process-step prevention lane 64. An interested item in the sample is decided on the basis of the reaction of the sample with the reagent.

公开(公告)号：JPH10282113A

公开(公告)日：1998-10-23

申请号：JP10300698

申请日：1998-04-14

Applicant: ABBOTT LAB

Inventor： ARNQUIST DAVID C ,  BARNES GRADY III ,  BUTTON RICHARD D ,  DUNN CHADWICK M ,  EAST RICHARD C JR ,  FRITCHIE PATRICK P ,  GALITZ CHARLES M ,  GARDNER GREGORY E ,  GRANDONE CASS J ,  GRAY ROBERT C ,  HOLEN JAMES T ,  LUOMA ROBERT P II ,  MCCOY JIMMY D ,  MITCHELL JAMES E ,  ADRIAN J MURRY ,  MURRAY DAVID W ,  RAMSEY JACK F ,  SLESZYNSKI NEAL T ,  TOTH JULIUS J

IPC: G01N33/483 ,  G01N33/49 ,  G01N33/543 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04

Abstract: PROBLEM TO BE SOLVED: To provide a method for forming a structure for deciding an item of concern contained in a sample. SOLUTION: In a process lane 28 in which process steps are selectively and automatically performed on a sample contained in a container 15, the effective moving length of the container 15 containing the sample is decided. The lane 28 is formed so that the lane 28 may become suitable to at least either one of a predetermined throughput and a predetermined physical dimension. At the time of deciding an item of concern, elements are arranged along the lane 28 so that the container 15 may move by the effective length.

公开(公告)号：JPH10142231A

公开(公告)日：1998-05-29

申请号：JP25559297

申请日：1997-09-19

Applicant: ABBOTT LAB

Inventor： ARNQUIST DAVID C ,  BARNES GRADY III ,  BUTTON RICHARD D ,  DUNN CHADWICK M ,  EAST RICHARD C JR ,  FRITCHIE PATRICK P ,  GALITZ CHARLES M ,  GRANDONE CASS J ,  GARDNER GREGORY E ,  GRAY ROBERT C ,  HOLEN JAMES T ,  LUOMA ROBERT P II ,  MCCORY JIMMY D ,  MITCHELL JAMES E ,  MURRAY ADRIAN JOHN ,  MURRAY DAVID W ,  RAMSEY JACK F ,  SLESZYNSKI NEAL T ,  TOTH JULIUS J

IPC: G01N33/483 ,  G01N33/49 ,  G01N33/543 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04

Abstract: PROBLEM TO BE SOLVED: To execute a process of determining concerned items in a sample by arranging a container selectively at either one of a process step execution lane and a process step avoiding lane. SOLUTION: A process lane 28 includes a process step execution lane 62 executing steps of a process, and a process step avoiding lane 64 avoiding the steps of the process. A container holding a sample moves along the process lane 28, and the reagent is put and mixed. The container is selectively arranged at the selected one of the process step execution lane 62 and process step avoiding lane 64, and concerned items in the sample are determined. Structure of selectively and automatically executing the steps of the process of determining the concerned items is arranged along the process lane 28 and includes bypass areas 58A, 58B, 58C.

公开(公告)号：JPH10142229A

公开(公告)日：1998-05-29

申请号：JP25559597

申请日：1997-09-19

Applicant: ABBOTT LAB

Inventor： ARNQUIST DAVID C ,  BARNES GRADY III ,  BUTTON RICHARD D ,  DUNN CHADWICK M ,  EAST RICHARD C JR ,  FRITCHIE PATRICK P ,  GALITZ CHARLES M ,  GARDNER GREGORY E ,  GRANDONE CASS J ,  GRAY ROBERT C ,  HOLEN JAMES T ,  LUOMA ROBERT P II ,  MCCORY JIMMY D ,  MITCHELL JAMES E ,  MURRAY ADRIAN J ,  MURRAY DAVID W ,  RAMSEY JACK F ,  SLESZYNSKI NEAL T ,  TOTH JULIUS J

IPC: G01N33/483 ,  G01N33/49 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04

Abstract: PROBLEM TO BE SOLVED: To determine concerned items in a sample by moving a container along a process lane, and executing a process step selectively and automatically to the sample in the container. SOLUTION: A process step is executed selectively and automatically to a sample in a container while moving the container along a process path 10 (process lane), that is, a plurality of slots 18 are arranged at a disc 16 of the process path 10, and the slots 18 move the container along the process path 10. When the container moves from a charging lane to the process lane, the container moves along the process lane by the motion of the disc 16 in order to determine concerned items in the sample. The process of determining the concerned items in the sample includes separation of solid/liquid phase, suction and cleaning of contents in the container, and the like. The process path 10 has such constitution as to be able to execute all the processes of determining the concerned items.

公开(公告)号：WO2010147896A3

公开(公告)日：2011-09-29

申请号：PCT/US2010038521

申请日：2010-06-14

Applicant: ABBOTT LAB ,  FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W

Inventor： FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W

IPC: G01N35/10

CPC classification number: G01N35/1002 ,  G01N1/28 ,  G01N35/1009 ,  G01N35/1016 ,  G01N35/1065 ,  G01N35/1074 ,  G01N2035/1025 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/25625 ,  Y10T436/2575

Abstract: A system for managing bulk liquids for an automated clinical analyzer. The system comprises (a) at least one local reservoir for storing a bulk liquid for impending use, (b) at least one container for holding a bulk liquid before the liquid is transferred to a local reservoir, and (c) a controller for monitoring the level of a bulk liquid in a local reservoir. The local reservoir for storing a bulk liquid for impending use can be a trough. The use of troughs for storing a reagent, a diluent, or some other treating agent for impending use enables an aspirating/dispensing device having a plurality of pipettes to aspirate and dispense the reagent, diluent, or other treating agent at a high rate of throughput. The controller can monitor the level of a liquid in (a) a local reservoir for storing a bulk liquid for imminent use and the level of liquid in a (b) container for holding a bulk liquid before the liquid is transferred to a local reservoir. In the laboratory automation system described herein, the container for holding a bulk liquid before the liquid is transferred to a local reservoir can be a bottle. Other desirable features in the system include, but are not limited to, pump(s), valves, liquid level sensors.

Abstract translation: 用于管理自动化临床分析仪的散装液体的系统。 该系统包括（a）至少一个用于储存即将使用的散装液体的局部储存器，（b）至少一个用于在液体被转移到局部储存器之前保持散装液体的容器，以及（c）用于监测的控制器 局部水库中大量液体的水平。 用于储存即将使用的散装液体的局部储存罐可以是槽。 用于储存用于即将使用的试剂，稀释剂或一些其它处理剂的槽使得具有多个移液管的抽吸/分配装置可以以高生产率将吸入和分配试剂，稀释剂或其它处理剂 。 控制器可以监测（a）用于储存即将使用的散装液体的局部储存器中的液体的液面，以及（b）容器中用于容纳大量液体的液体的液面，然后液体被转移到局部储存器。 在本文所述的实验室自动化系统中，在将液体转移到局部储存器之前用于保持散装液体的容器可以是瓶子。 该系统中的其它期望特征包括但不限于泵，阀，液位传感器。

公开(公告)号：WO2009061641A3

公开(公告)日：2009-08-27

申请号：PCT/US2008081494

申请日：2008-10-29

Applicant: ABBOTT LAB ,  FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W

Inventor： FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W

IPC: B01L3/00 ,  C12Q1/68 ,  G01N35/00

CPC classification number: G01N35/028 ,  B01L3/5085 ,  B01L2300/0829 ,  G01N35/0098 ,  G01N35/0099 ,  G01N35/1002 ,  G01N35/1065 ,  G01N2035/00564 ,  G01N2035/0406 ,  G01N2035/1051 ,  Y02P20/582 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/2575

Abstract: A laboratory automation system that is capable of carrying out clinical chemistry assays, immunoassays, amplification of nucleic acid assays, and any combination of the foregoing, said laboratory automation system employing at least one of micro-well plates and deep multi-well plates as reaction vessels. The use of micro-well plates as reaction vessels enables the laboratory automation system to assume a variety of arrangements, i.e., the laboratory automation system can comprise a variety of functional modules that can be arranged in various ways. In order to effectively carry out immunoassays by means of micro-well plates, a technique known as inverse magnetic particle processing can be used to transfer the product(s) of immunoassays from one micro-well of a micro-well plate to another.

Abstract translation: 实验室自动化系统能够进行临床化学测定，免疫测定，核酸测定的扩增以及前述的任何组合，所述实验室自动化系统采用微孔板和深度多孔板中的至少一种作为反应 船只。 使用微孔板作为反应容器使得实验室自动化系统能够采取各种布置，即，实验室自动化系统可以包括可以以各种方式布置的各种功能模块。 为了有效地通过微孔板进行免疫测定，可以使用称为反向磁性颗粒处理的技术将免疫测定的产物从微孔板的一个微孔转移到另一微孔板。

公开(公告)号：WO2008014117A2

公开(公告)日：2008-01-31

申请号：PCT/US2007073201

申请日：2007-07-11

Applicant: ABBOTT LAB ,  FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W ,  SCHWARTZ OSCAR F

Inventor： FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W ,  SCHWARTZ OSCAR F

IPC: G01N35/00

CPC classification number: G01N35/00732 ,  B01L3/545 ,  B01L2300/022 ,  B01L2300/024 ,  G01N2035/00782 ,  G01N2035/00851

Abstract: A system for automation of laboratory analyzers that utilizes radio frequency identification (RFID) tags and radio frequency identification (RFID) readers to identify containers and vessels, and the contents thereof, that are employed in the system. Radio frequency identification tags, conforming to the guidelines of ISO 14443 or ISO 15693 or ISO 18000, are positioned on the items of interest, such as, for example, reagent containers, sample containers, and microplates. These tags can be read by and written to by either a moving antenna of a RFID reader or a stationary antenna of a RFID reader. Reading of RFID tags and writing to RFID tags are controlled by software.

Abstract translation: 实验室分析仪自动化系统，利用射频识别（RFID）标签和射频识别（RFID）读取器识别系统中使用的容器和容器及其内容。 射频识别标签符合ISO 14443或ISO 15693或ISO 18000标准，位于感兴趣的项目上，例如试剂容器，样品容器和微孔板。 这些标签可以通过RFID阅读器的移动天线或RFID阅读器的固定天线读取和写入。 读取RFID标签并写入RFID标签由软件控制。