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    STRUCTURE, METHOD AND PROCESS FOR DETERMINATION OF AN ITEM OF INTEREST IN A SAMPLE
    7.
    发明专利
    STRUCTURE, METHOD AND PROCESS FOR DETERMINATION OF AN ITEM OF INTEREST IN A SAMPLE 未知

    公开(公告)号：CA2214125A1

    公开(公告)日：1998-03-19

    申请号：CA2214125

    申请日：1997-08-28

    Applicant: ABBOTT LAB

    Inventor： BARNES GRADY III ,  SLESZYNSKI NEAL T ,  RAMSEY JACK F ,  MURRAY ADRIAN J ,  HOLEN JAMES T ,  GRANDONE CASS J ,  GARDNER GREGORY E ,  MURRAY DAVID W ,  GALITZ CHARLES M ,  EAST RICHARD C JR ,  FRITCHIE PATRICK P ,  BUTTON RICHARD D ,  MITCHELL JAMES E ,  GRAY ROBERT C ,  TOTH JULIUS J ,  ARNQUIST DAVID C ,  MCCOY JIMMY D ,  DUNN CHADWICK M ,  LUOMA ROBERT P II

    IPC: G01N35/02

    Abstract: The embodiments disclosed relate to determination of an item of interest in a sample. One embodiment relates to a structure which comprises a process path. The process path comprises a process lane including a process step performance lane where a process step is performed, and a process step avoidance lane where the process step is avoided. A first prime mover is operatively connected with the process path for moving a container holding the sample along the process path. A first pipetting system is operatively associated with the process path for introducing the sample to the container. A second pipetting system is operatively associated with the process path for introducing a reagent to the container. A device is operatively connected with the process path and is selectively engagable with the container for mixing the sample and the reagent in the container. A second prime mover is operatively connected with the process path for selectively positioning the container in a selected one of the process step performance lane and the process step avoidance lane. A reader is operatively connected with the process path for determining the item of interest in the sample based upon a reaction between the sample and the reagent; the embodiments disclosed also related to determination of an item of interestin a sample. In one method, a process path comprising a process lane including a process step performance lane where a process step is performed, and a process step avoidance lane where the process step is avoided is provided. A container holding the sample is moved along the process path. The sample is introduced to the container. A reagent is introduced to the container. The sample and the reagent are mixed in the container. The container is selectively positioned in a selected one of the process step performance lane and the process step avoidance lane. The item of interest in the sample is determined based upon a reaction between the sample and the reagent; embodiments also described herein provide methods of performing a process for determining an item of interest in a sample. In one embodiment, a container for holding the sample is accepted in a process lane where a process step is selectively automatically performed on the sample in the container. The process step is selectively automatically performed on the sample in the container. An effective length of the process lane is maintained constant while a physical length of the process lane is selectively varied.

    LOCKING RACK AND DISPOSABLE SAMPLE CARTRIDGE
    9.
    发明专利
    LOCKING RACK AND DISPOSABLE SAMPLE CARTRIDGE 未知

    公开(公告)号：CA1318840C

    公开(公告)日：1993-06-08

    申请号：CA564514

    申请日：1988-04-19

    Applicant: ABBOTT LAB

    Inventor： GRANDONE CASS J

    IPC: G01N33/48 ,  B01L3/00 ,  G01N21/03 ,  G01N33/543 ,  G01N35/04 ,  G01N35/00 ,  B01L9/00

    Abstract: A plurality of disposable cartridges, each having a plurality of wells including at least one assay reaction well, are loaded in a plurality of openings arranged radially around a rack of a carousel. Securing of the cartridges in a predetermined orientation and position in said openings is ensured by means of alignment and securing means on the cartridges and corresponding means on the rack. A locking hub with tangs is mounted on the rack and is rotated to cause the tangs to contact locator tabs on each cartridge to force locator nubs on each of the cartridges radially into corresponding notches on the rack, and to accuratell wedge the cartridges against the outer periphery of the rack. The carousel indexes for positioning the cartridges under a variety of stations, one of which generally contains an optical reader such as a fluorometer.

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