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公开(公告)号:BR112012008833A2
公开(公告)日:2015-09-08
申请号:BR112012008833
申请日:2010-10-15
Applicant: ABBOTT LAB
Inventor: LIU JUNJIAN , HONORE MARIE P , KAMATH RAJESH V , GHAYUR TARIQ
Abstract: imunoglobulinas de domínio variável duplo e usos das mesmas. a presente invenção se refere a proteínas de ligação multiespecíficas e multivalentes manipuladas, métodos de preparação e, especificamente, a seus usos na prevenção, diagnóstico, e/ou tratamento de doenças.
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公开(公告)号:BRPI0720124A2
公开(公告)日:2014-03-04
申请号:BRPI0720124
申请日:2007-12-12
Applicant: ABBOTT LAB
Inventor: GOPALAKRISHNAN MURALI , HONORE MARIE P , LEE CHIH-HUNG , MALYSZ JOHN , JI JIANGUO , LI TAO , SCHRIMPF MICHAEL R , SIPPY KEVIN B , ANDERSON DAVID J
IPC: A61K31/4245 , A61K45/06 , A61P25/28
Abstract: The invention relates to a composition comprising a neuronal nicotinic receptor ligand and an ±4²2 positive allosteric modulator, a method of using the same, and a related article of manufacture.
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公开(公告)号:CO6541597A2
公开(公告)日:2012-10-16
申请号:CO12079008
申请日:2012-05-14
Applicant: ABBOTT LAB
Inventor: GHAYUR TARIQ , KAMATH RAJESH V , LIU JUNJIAN , HONORE MARIE P
IPC: C12P21/08
Abstract: Proteínas de unión multivalentes y multiespecíficas modificadas, métodos para su obtención y específicamente sus usos en la prevención, diagnóstico y/o tratamiento de enfermedades.
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公开(公告)号:MX2009006235A
公开(公告)日:2009-06-22
申请号:MX2009006235
申请日:2007-12-12
Applicant: ABBOTT LAB
Inventor: JI JIANGUO , SCHRIMPF MICHAEL R , LI TAO , SIPPY KEVIN B , ANDERSON DAVID J , GOPALAKRISHNAN MURALI , MALYSZ JOHN , LEE CHIH-HUNG , HONORE MARIE P
IPC: A61K31/4245 , A61K45/06 , A61P25/28
Abstract: La invención se refiere a una composición que comprende un ligando de un receptor nicotínico neuronal y un modulador alostérico positivo de a4ß2, un método para usarla y un artículo de fabricación relacionado.
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公开(公告)号:CA2671683A1
公开(公告)日:2008-06-19
申请号:CA2671683
申请日:2007-12-12
Applicant: ABBOTT LAB
Inventor: ANDERSON DAVID J , LI TAO , SCHRIMPF MICHAEL R , SIPPY KEVIN B , JI JIANGUO , GOPALAKRISHNAN MURALI , HONORE MARIE P , MALYSZ JOHN , LEE CHIH-HUNG
IPC: A61K31/4245 , A61K45/06 , A61P25/28
Abstract: The invention relates to a composition comprising a neuronal nicotinic re ceptor ligand and an .alpha.4.beta.2 positive allosteric modulator, a method of using the same, and a related article of manufacture.
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公开(公告)号:AU2007333129A1
公开(公告)日:2008-06-19
申请号:AU2007333129
申请日:2007-12-12
Applicant: ABBOTT LAB
Inventor: LEE CHIH-HUNG , MALYSZ JOHN , JI JIANGUO , LI TAO , SIPPY KEVIN B , GOPALAKRISHNAN MURALI , ANDERSON DAVID J , SCHRIMPF MICHAEL R , HONORE MARIE P
IPC: A61K31/4245 , A61K45/06 , A61P25/28
Abstract: The invention relates to a composition comprising a neuronal nicotinic receptor ligand and an ±4²2 positive allosteric modulator, a method of using the same, and a related article of manufacture.
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