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公开(公告)号：ES2244094T3
公开(公告)日：2005-12-01
申请号：ES98956338
申请日：1998-10-29
Applicant: ABBOTT LAB
Inventor： PHAN LY TAM , OR YAT SUN , CHU DANIEL T , PLATTNER JACOB J , CHEN YAN , CLARK RICHARD F
IPC: A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08 , A61K31/70
Abstract: Un compuesto que tiene la fórmula: o una sal farmacéuticamente aceptable del mismo, donde Rp es hidrógeno o un grupo hidroxi protector; X es F, Cl o Br; y R1 se selecciona entre el grupo compuesto por (1) -CH2-CH=CH-Y, en la que Y se selecciona entre el grupo compuesto por (a) H, (b) fenilo, (c) quinolinilo, (d) naftiridinilo, (e) heteroarilo sustituido, donde el heteroarilo es piridinilo, quinolinilo o tiofenilo sustituido con carboxamida, alquilamino, dialquilamino, carboxaldehído, nitro, -CN, -CH(=N-OH), -CH(=N-NH2), -CH(=N-N=C(CH3)2), piridilo, tiofenilo o pirimidinilo o amino N-protegido, donde el grupo N-protector es t- butiloxicarbonilo; (f) quinoxalinilo, y (g) (aril)oilo, donde el arilo es fenilo; y (2) -CH2-C=C-Y, en la que Y es como se ha definido anteriormente.
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公开(公告)号：PT1027362E
公开(公告)日：2005-08-31
申请号：PT98956338
申请日：1998-10-29
Applicant: ABBOTT LAB
Inventor： OR YAT SUN , CHU DANIEL T , CLARK RICHARD F , PLATTNER JACOB J , PHAN LY TAM , YAN CHEN
IPC: A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08 , A61K31/70
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公开(公告)号：ES2218604T3
公开(公告)日：2004-11-16
申请号：ES96936579
申请日：1996-10-17
Applicant: ABBOTT LAB
Inventor： OR YAT SUN , PHAN LY TAM , CHU DANIEL T , SPINA KENNETH P , HALLAS ROBERT , ELLIOTT RICHARD L
Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R , R and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.
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公开(公告)号：AT259823T
公开(公告)日：2004-03-15
申请号：AT96936579
申请日：1996-10-17
Applicant: ABBOTT LAB
Inventor： OR YAT SUN , PHAN LY TAM , CHU DANIEL T , SPINA KENNETH P , HALLAS ROBERT , ELLIOTT RICHARD L
Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R , R and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.
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公开(公告)号：UY26964A1
公开(公告)日：2002-06-20
申请号：UY26964
申请日：2001-10-12
Applicant: ABBOTT LAB
Inventor： MA ZHENKUN , ZHANG SOUMING , PHAN LY TAM , DJURIC STEVAN , CLARK RICK F
IPC: A61K31/7056 , A61P31/04 , C07H17/08 , A61K31/7048
Abstract: Compuestos de fórmula I son útiles para el tratamiento de infeciones bacterianas pero sin producir el efecto colateral de intolerancia gastrointestinal. También se revelan composiciones que contienen los compuestos y métodos de tratamiento que los utilizan.
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Patent Agency Ranking
公开(公告)号：CA2372270A1
公开(公告)日：2000-11-23
申请号：CA2372270
申请日：2000-05-04
Applicant: ABBOTT LAB
Inventor： PHAN LY TAM , OR YAT SUN , MA ZHENKUN , CLARK RICHARD F , SUOMING ZHANG
IPC: A61K31/7048 , A61P31/04 , C07H17/08 , A61K31/70
Abstract: A compound having the formula selected from the group consisting of a compou nd of formula (I), a compound of formula (II), and a compound of formula (III) as well as pharmaceutically acceptable salts, esters, solvates, metabolites, an d prodrugs thereof, are useful in treating bacterial infections. Also provided are pharmaceutically acceptable compositions, methods of treating bacterial infections, and processes for the preparation of the compounds.
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公开(公告)号：CZ231599A3
公开(公告)日：1999-12-15
申请号：CZ231599
申请日：1997-04-07
Applicant: ABBOTT LAB
Inventor： OR YAT SUN , PHAN LY TAM , CHU DANIAL T , SPINA KENNATH P , HALLAS ROBERT , ELLIOTT RICHARD L , TUFANO MICHAEL
IPC: C07H17/00 , A61K31/00 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P31/00 , A61P31/04 , C07H17/08 , A61K31/71
Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of the formula:wherein A, B, D and E, R1, R2, and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of bacterial infections with such compositions, and processes for the preparation of the compounds.
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公开(公告)号：AU7447096A
公开(公告)日：1997-05-29
申请号：AU7447096
申请日：1996-10-17
Applicant: ABBOTT LAB
Inventor： OR YAT SUN , PHAN LY TAM , CHU DANIEL T , SPINA KENNETH P , HALLAS ROBERT , ELLIOTT RICHARD L
Abstract: Compounds, or pharmaceutically acceptable salts and esters thereof, of formulae (I); (II); (III) or (IV) wherein A, B, D and E, R , R and Z are specifically defined, having antibacterial activity, pharmaceutical compositions containing said compounds, treatment of antibacterial infections with such compositions, and processes for the preparation of the compounds.
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公开(公告)号：CA2372270C
公开(公告)日：2008-07-22
申请号：CA2372270
申请日：2000-05-04
Applicant: ABBOTT LAB
Inventor： MA ZHENKUN , SUOMING ZHANG , PHAN LY TAM , CLARK RICHARD F , OR YAT SUN
IPC: C07H17/08 , A61K31/7048 , A61P31/04
Abstract: A compound having the formula selected from the group consisting of a compou nd of formula (I), a compound of formula (II), and a compound of formula (III) as well as pharmaceutically acceptable salts, esters, solvates, metabolites, an d prodrugs thereof, are useful in treating bacterial infections. Also provided are pharmaceutically acceptable compositions, methods of treating bacterial infections, and processes for the preparation of the compounds.
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公开(公告)号：DE60039122D1
公开(公告)日：2008-07-17
申请号：DE60039122
申请日：2000-12-01
Applicant: ABBOTT LAB
Inventor： PHAN LY TAM , OR YAT SUN , MA ZHENKUN
IPC: C07H17/00 , A61K31/7052 , A61K31/7056 , A61P31/04 , C07H17/08
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