公开(公告)号：WO2006091221A9

公开(公告)日：2007-02-01

申请号：PCT/US2005023635

申请日：2005-06-30

Applicant: CHEMIMAGE CORP ,  NELSON MATTHEW P ,  TREADO PATRICK ,  ATTANUCCI JASON

Inventor： NELSON MATTHEW P ,  TREADO PATRICK ,  ATTANUCCI JASON

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01N15/1475 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/65 ,  G01N2015/1497

Abstract: The invention relates to methods of assessing one or more geometric properties of a particle of a substance using an spectroscopic property of the substance. The method is useful, for example, for assessing particle sizes and size distributions in mixtures containing both particles of the substance and other materials.

Abstract translation: 本发明涉及使用该物质的光谱特性评估物质颗粒的一种或多种几何性质的方法。 该方法例如用于评估含有物质颗粒和其它材料的混合物的粒度和尺寸分布是有用的。

公开(公告)号：WO2006007064A3

公开(公告)日：2006-04-20

申请号：PCT/US2005016141

申请日：2005-05-06

Applicant: CHEMIMAGE CORP ,  STEWART SHONA ,  NELSON MATTHEW P ,  DEMUTH JOSEPH E ,  TREADO PATRICK J

Inventor： STEWART SHONA ,  NELSON MATTHEW P ,  DEMUTH JOSEPH E ,  TREADO PATRICK J

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01J3/44 ,  G01J3/0297 ,  G01N21/65

Abstract: The disclosure relates to a substrate material for the improved detection, resolution and imaging of biological material for spectroscopic characterization by Raman of optical imaging spectroscopy. The substrate provides a uniform, optically flat, highly reflective surface which can be made hydrophobic to prevent spreading of the sample and facilitating its optical evaluation. Moreover, the substrate can be coated with a material that does not emit Raman scattered photons when exposed to said illuminating photons. The principles disclosed herein allow a low spectroscopic background particularly suitable for examining small samples or samples having low concentrations of the suspected component.

Abstract translation: 本公开涉及一种用于改进的光学成像光谱术的拉曼光谱表征的生物材料的检测，分辨率和成像的基底材料。 基材提供均匀的，光学平坦的高度反射表面，其可以制成疏水性的，以防止样品扩散并促进其光学评估。 此外，衬底可以涂覆有当暴露于所述照射光子时不发射拉曼散射光子的材料。 本文公开的原理允许特别适用于检查小样品或具有低浓度可疑成分的样品的低光谱背景。

公开(公告)号：EP1651934A4

公开(公告)日：2010-08-25

申请号：EP04820713

申请日：2004-06-24

Applicant: CHEMIMAGE CORP

Inventor： GARDNER CHARLES W JR ,  MAIER JOHN S ,  NELSON MATTHEW P ,  SCHWEITZER ROBERT C ,  TREADO PATRICK J ,  VANNI G STEVEN ,  WOLFE JULIANNE

IPC: G01J3/44 ,  G01J3/02 ,  G01J3/10 ,  G01N21/35 ,  G01N21/64 ,  G01N21/65

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0272 ,  G01J3/10 ,  G01N21/35 ,  G01N21/3577 ,  G01N21/6458 ,  G01N21/6486 ,  G01N21/65 ,  G01N2021/6417 ,  G01N2021/6423 ,  G01N2021/656 ,  G01N2201/0221

公开(公告)号：EP1902301A4

公开(公告)日：2010-09-22

申请号：EP06851106

申请日：2006-06-09

Applicant: CHEMIMAGE CORP

Inventor： TREADO PATRICK J ,  NELSON MATTHEW P ,  HUBBLE HUGH W II ,  NEISS JASON

IPC: G01J3/02 ,  G01J3/28 ,  G01J3/36 ,  G01J3/44 ,  G01N21/35 ,  G01N21/64 ,  G01N21/65 ,  G01N21/71 ,  G01N33/22

CPC classification number: G01J3/36 ,  G01J3/02 ,  G01J3/0221 ,  G01J3/0264 ,  G01J3/2823 ,  G01J3/44 ,  G01N21/359 ,  G01N21/6456 ,  G01N21/65 ,  G01N21/718 ,  G01N2021/1738 ,  G01N2021/174 ,  G01N2021/1744

公开(公告)号：EP1766351A4

公开(公告)日：2009-12-02

申请号：EP05857503

申请日：2005-06-30

Applicant: CHEMIMAGE CORP

Inventor： NEISS JASON ,  NELSON MATTHEW P ,  TREADO PATRICK ,  SCHWEITZER ROBERT

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01J3/10 ,  G01J3/32 ,  G01N21/21 ,  G01N21/6428 ,  G01N21/6458 ,  G01N21/65 ,  G01N2021/6417 ,  G01N2021/6484 ,  G01N2021/656

公开(公告)号：EP1463926A4

公开(公告)日：2010-09-08

申请号：EP03708825

申请日：2003-01-10

Applicant: CHEMIMAGE CORP

Inventor： GARDNER CHARLES W JR ,  MAIER JOHN S ,  NELSON MATTHEW P ,  SCHWEITZER ROBERT C ,  TREADO PATRICK J ,  VANNI G STEVEN ,  WARE JULIANE

IPC: C12Q1/04 ,  G01N21/31 ,  G01N21/64 ,  G01N21/65 ,  G01J3/44

CPC classification number: G01N21/6486 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/2823 ,  G01J3/44 ,  G01N21/31 ,  G01N21/33 ,  G01N21/359 ,  G01N21/645 ,  G01N21/6456 ,  G01N21/6458 ,  G01N21/65 ,  G01N2021/1736 ,  G01N2021/6421 ,  G01N2021/6423 ,  G01N2021/656

公开(公告)号：EP1991844A4

公开(公告)日：2009-11-04

申请号：EP07757944

申请日：2007-03-05

Applicant: CHEMIMAGE CORP

Inventor： GARDNER CHARLES W ,  MAIER JOHN S ,  NELSON MATTHEW P ,  SCHWEITZER ROBERT C ,  TREADO PARTRICK J ,  VANNI G STEVEN ,  WOLFE JULIANNE ,  DEMUTH JOSEPH E ,  NEISS JASON H ,  WANG CHENHUI

IPC: G01J3/44 ,  G01J3/28 ,  G01J3/45

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/26 ,  G01J3/28 ,  G01J3/2823 ,  G01N21/6456 ,  G01N21/65 ,  G01N2021/6423 ,  G01N2201/0221

公开(公告)号：EP1787149A4

公开(公告)日：2008-07-16

申请号：EP05789312

申请日：2005-08-19

Applicant: CHEMIMAGE CORP

Inventor： TUSCHEL DAVID ,  NELSON MATTHEW P ,  DEMUTH JOSEPH E

IPC: G02B6/06 ,  G01J3/44

CPC classification number: A61B1/00165 ,  A61B1/043 ,  A61B1/07 ,  A61B5/0075 ,  A61B5/0084 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0291 ,  G01J3/32 ,  G01J3/44 ,  G01J2003/1213 ,  G01N21/33 ,  G01N21/359 ,  G01N21/474 ,  G01N21/645 ,  G01N21/65 ,  G01N2021/3155 ,  G01N2021/4742 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6484 ,  G01N2021/656 ,  G02B6/06 ,  G02B6/29398 ,  G02B23/2423 ,  G02B23/2469

Abstract: The disclosure generally relates to a method and apparatus for a fiberscope. In one embodiment, the disclosure relates to a chemical imaging fiberscope for imaging and collecting optical spectra from a sample having at least one illumination fiber (14) for transmitting light from a first an a second light source to a distal end of a fiberscope; a dichroic mirror (30) disposed at said distal end of the fiberscope such that the light from said first light source passes substantially straight through said mirror and light of a predetermined wavelength from said second light source is substantially reflected by said mirror toward said sample to thereby illuminate said sample; and at least one collection fiber (38) for receiving light from said illuminated sample and transmitting the received light to an optical device.