中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

32 records (took 0.024 seconds)

    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME
    24.
    发明专利
    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME 未知

    公开(公告)号：SG10202107927VA

    公开(公告)日：2021-08-30

    申请号：SG10202107927V

    申请日：2005-01-25

    Applicant: FLUIDIGM CORP

    Inventor： GROSSMAN ROBERT ,  UNGER MARC ,  LAM PHILLIP ,  CHOU HOU-PU ,  KIMBALL JAKE ,  PIEPRZYK MARTIN

    IPC: B01J19/00 ,  B01L3/00 ,  B01L3/06 ,  B01L9/00 ,  B01L99/00 ,  C30B7/00 ,  C30B29/58

    Abstract: The present invention provides for microfluidic devices and methods for their use. The invention further provides for apparatus and systems for using the microfluidic devices, analyze reactions carried out in the microfluidic devices, and systems to generate, store, organize, and analyze data generated from using the microfluidic devices. The invention further provides methods of using and making microfluidic systems and devices which, in some embodiments, are useful for crystal formation. In one embodiment, an apparatus includes a platen having a platen face with one or more fluid ports therein. The fluid ports spatially correspond to one or more wells on a surface of the microfluidic device. A platform for holding the microfluidic device relative to the platen is included, and a platen actuator for urging the platen against the microfluidic device so that at least one of the fluid ports of the platen is urged against one of the wells to form a pressure chamber comprising the well and the port, so that when pressurized fluid is introduced or removed into or from the pressure chamber through one of the ports, fluid pressure is changed therein.

    HAPLOIDOME DETERMINATION BY DIGITIZED TRANSPOSONS
    25.
    发明专利
    HAPLOIDOME DETERMINATION BY DIGITIZED TRANSPOSONS 未知

    公开(公告)号：CA2949952C

    公开(公告)日：2021-03-23

    申请号：CA2949952

    申请日：2015-05-21

    Applicant: FLUIDIGM CORP

    Inventor： XI LEI ,  WANG XIAOHUI ,  UNGER MARC ,  RUFF DAVID

    IPC: C12N15/10 ,  C12N15/09 ,  C12N15/63 ,  C12P19/34

    Abstract: In certain embodiments, the present invention provides a way of "digitally" marking different the alleles of different chromosomes by using a transposase to insert differently barcoded transposons into genomic DNA before further analysis. According to this method, each allele becomes marked with a unique pattern of transposon barcodes. Because each unique pattern of transposon barcodes identifies a particular allele, the method facilitates determinations of ploidy and copy number variation, improves the ability to discriminate among homozygotes, heterozygotes, and patterns arising from sequencing errors, and allows loci separated by uninformative stretches of DNA to be identified as linked loci, thereby facilitating haplotype determinations. Also provided is a novel artificial transposon end that includes a barcode sequence in two or more positions that are not essential for transposition.

    MICROFLUIDIC DEVICES AND METHODS OF USING SAME
    26.
    发明专利
    MICROFLUIDIC DEVICES AND METHODS OF USING SAME 未知

    公开(公告)号：CA2807564C

    公开(公告)日：2014-01-28

    申请号：CA2807564

    申请日：2004-04-05

    Applicant: FLUIDIGM CORP

    Inventor： MCBRIDE LINCOLN ,  LUCERO MICHAEL ,  UNGER MARC ,  NASSEF HANY RAMEZ ,  FACER GEOFFREY

    IPC: B81B3/00 ,  B81B7/04 ,  C12M1/34 ,  C12M1/40 ,  C12Q1/68 ,  C40B30/00 ,  C40B60/00 ,  G01N33/48

    Abstract: A microfluidic device, with elastomeric components, and having a flow channel, wherein said flow channel has a plurality of blind flow channels opening into and in fluid communication with the flow channel, each blind flow channel having an aperture portion, a channel portion and a terminus portion, and wherein a region at the terminus of each blind flow channel defines a reaction site. Each blind flow channel is associated with a valve that when closed isolates the reaction site from the flow channel. The valves associated with each of the plurality of blind flow channels in fluid communication with the flow channel are under the control of a common control channel and are coordinately closed or opened.

    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME
    28.
    发明专利
    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME 未知

    公开(公告)号：SG187392A1

    公开(公告)日：2013-02-28

    申请号：SG2012094876

    申请日：2005-01-25

    Applicant: FLUIDIGM CORP

    Inventor： GROSSMAN ROBERT ,  UNGER MARC ,  LAM PHILLIP ,  CHOU HOU-PU ,  KIMBALL JAKE ,  PIEPRZYK MARTIN

    IPC: B01J19/00 ,  B01L3/00 ,  B01L3/06 ,  B01L9/00 ,  B01L99/00 ,  C30B7/00 ,  C30B29/58

    Abstract: The present invention provides for microfluidic devices and methods for their use. The invention further provides for apparatus and systems for using the microfluidic devices, analyze reactions carried out in the microfluidic devices, and systems to generate, store, organize, and analyze data generated from using the microfluidic devices. The invention further provides methods of using and making microfluidic systems and devices which, in some embodiments, are useful for crystal formation. In one embodiment, an apparatus includes a platen having a platen face with one or more fluid ports therein. The fluid ports spatially correspond to one or more wells on a surface of the microfluidic device. A platform for holding the microfluidic device relative to the platen is included, and a platen actuator for urging the platen against the microfluidic device so that at least one of the fluid ports of the platen is urged against one of the wells to form a pressure chamber comprising the well and the port, so that when pressurized fluid is introduced or removed into or from the pressure chamber through one o f the ports, fluid pressure is changed therein.FIG. 14B

    DISPOSITIVOS FORMADORES DE CRISTAL Y SISTEMAS Y METODOS PARA HACER Y UTILIZAR LOS MISMOS.
    29.
    发明专利
    DISPOSITIVOS FORMADORES DE CRISTAL Y SISTEMAS Y METODOS PARA HACER Y UTILIZAR LOS MISMOS. 未知

    公开(公告)号：MXPA06008399A

    公开(公告)日：2008-03-07

    申请号：MXPA06008399

    申请日：2005-01-25

    Applicant: FLUIDIGM CORP

    Inventor： GROSSMAN ROBERT ,  UNGER MARC ,  LAM PHILLIP ,  CHOU HOU-PU ,  KIMBALL JAKE ,  PIERPRZYK MARTIN

    IPC: G01N33/00 ,  B01J19/00 ,  B01L3/00 ,  B01L3/06 ,  B01L9/00 ,  B01L99/00 ,  C30B7/00 ,  C30B29/58

    Abstract: La presente invencion proporciona dispositivos de microfluido y metodos para su uso. La invencion ademas proporciona aparatos y sistemas para usar los dispositivos de microfluido, analizar reacciones realizadas en los dispositivos de microfluido, y sistemas para generar, almacenar, organizar, y analizar datos generados del uso de los dispositivos de microfluido. La invencion ademas proporciona metodos para usar y hacer sistemas y dispositivos de microfluido que, en algunas modalidades, son utiles para la formacion de cristal. En una modalidad, un aparato incluye una platina que tiene una cara de platina con uno o mas puertos de fluido en la misma. Los puertos de fluido espacialmente corresponden a uno o mas pozos sobre una superficie del dispositivo de microfluido. Se incluye una plataforma para sostener el dispositivo de microfluido con relacion a la platina, y un accionador de platina para empujar la platina contra el dispositivo de microfluido de manera que por lo menos uno de los puertos de fluido de la platina es empujado contra uno de los pozos para formar una camara de presion que comprende el pozo y el puerto, de manera que ciando se introduce o remueve fluido presurizado hacia o desde la camara de presion a traves de uno de los puertos, la presion de fluido es cambiada ahi.

Patent Agency Ranking