公开(公告)号：ES2061447T3

公开(公告)日：1994-12-16

申请号：ES87103938

申请日：1987-03-18

Applicant: HOECHST AG

Inventor： HOCK FRANZ DR ,  SCHOLTHOLT JOSEF PROF DR ,  URBACH HANSJORG DR ,  HENNING RAINER DR ,  LERCH ULRICH DR ,  NICKEL WOLF-ULRICH DR ,  RUGER WOLFGANG DR

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  A61K37/02 ,  A61K37/64

Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.

公开(公告)号：CS354591A3

公开(公告)日：1992-06-17

申请号：CS354591

申请日：1991-11-22

Applicant: HOECHST AG

Inventor： WAGNER ADALBERT DR ,  HENNING RAINER DR ,  NICKEL WOLF-ULRICH DR

IPC: A61K31/41 ,  A61K31/425 ,  A61P9/12 ,  A61P43/00 ,  C07D263/06 ,  C07D417/04 ,  C07D417/06 ,  C12N9/99 ,  C07D263/04 ,  A61K31/42

Abstract: The invention relates to compounds of the formula in which W represents -CO-, -O-CO-, -SO2- or -NH-CO-, R , R , R , R , R and R represent hydrogen or an organic radical and R denotes alkyl, cycloalkyl or cycloalkylalkyl, processes for their preparation, intermediates and their use in the preparation of inhibitors of renin and HIV protease.

公开(公告)号：DE4037437A1

公开(公告)日：1992-05-27

申请号：DE4037437

申请日：1990-11-24

Applicant: HOECHST AG

Inventor： WAGNER ADALBERT DR ,  HENNING RAINER DR ,  NICKEL WOLF-ULRICH DR

IPC: A61K31/41 ,  A61K31/425 ,  A61P9/12 ,  A61P43/00 ,  C07D263/06 ,  C07D417/04 ,  C07D417/06 ,  C12N9/99

Abstract: The invention relates to compounds of the formula in which W represents -CO-, -O-CO-, -SO2- or -NH-CO-, R , R , R , R , R and R represent hydrogen or an organic radical and R denotes alkyl, cycloalkyl or cycloalkylalkyl, processes for their preparation, intermediates and their use in the preparation of inhibitors of renin and HIV protease.

公开(公告)号：CS8906519A3

公开(公告)日：1992-05-13

申请号：CS651989

申请日：1987-03-27

Applicant: HOECHST AG

Inventor： HOCK FRANZ DR ,  SCHOLTHOLT JOSEF PROF DR ,  URBACH HANSJORG DR ,  HENNING RAINER DR ,  LERCH ULRICH DR ,  NICKEL WOLF-ULRICH DR ,  RUGER WOLFGANG DR

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  C07C103/50 ,  C07C103/68

CPC classification number: C07K5/0222 ,  A61K38/00

公开(公告)号：CS8702126A3

公开(公告)日：1992-04-15

申请号：CS212687

申请日：1987-03-27

Applicant: HOECHST AG

Inventor： HOCK FRANZ DR ,  SCHOLTHOLT JOSEF PROF DR ,  URBACH HANSJORG DR ,  HENNING RAINER DR ,  LERCH ULRICH DR ,  NICKEL WOLF-ULRICH DR ,  RUGER WOLFGANG DR

IPC: C07K14/81 ,  A61K38/00 ,  A61P9/12 ,  A61P25/28 ,  C07C235/02 ,  C07K1/06 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  C07C233/50 ,  C07C233/68

CPC classification number: C07K5/0222 ,  A61K38/00