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公开(公告)号:CS276385B6
公开(公告)日:1992-05-13
申请号:CS651989
申请日:1987-03-27
Applicant: HOECHST AG
Inventor: HOCK FRANZ DR , SCHOLTHOLT JOSEF PROF DR , URBACH HANSJORG DR , HENNING RAINER DR , LERCH ULRICH DR , NICKEL WOLF-ULRICH DR , RUGER WOLFGANG DR
IPC: C07K14/81 , A61K38/00 , A61P9/12 , A61P25/28 , C07C235/02 , C07K1/06 , C07K1/113 , C07K5/02 , C07K5/06 , C07C103/50
Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.
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公开(公告)号:CS276179B6
公开(公告)日:1992-04-15
申请号:CS212687
申请日:1987-03-27
Applicant: HOECHST AG
Inventor: HOCK FRANZ DR , SCHOLTHOLT JOSEF PROF DR , URBACH HANSJORG DR , HENNING RAINER DR , LERCH ULRICH DR , NICKEL WOLF-ULRICH DR , RUGER WOLFGANG DR
IPC: C07K14/81 , A61K38/00 , A61P9/12 , A61P25/28 , C07C235/02 , C07K1/06 , C07K1/113 , C07K5/02 , C07K5/06 , C07C237/00
Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.
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公开(公告)号:CS212687A3
公开(公告)日:1992-04-15
申请号:CS212687
申请日:1987-03-27
Applicant: HOECHST AG
Inventor: HOCK FRANZ DR , SCHOLTHOLT JOSEF PROF DR , URBACH HANSJORG DR , HENNING RAINER DR , LERCH ULRICH DR , NICKEL WOLF-ULRICH DR , RUGER WOLFGANG DR
IPC: C07K14/81 , A61K38/00 , A61P9/12 , A61P25/28 , C07C235/02 , C07K1/06 , C07K1/113 , C07K5/02 , C07K5/06 , C07C233/50 , C07C233/68
Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.
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公开(公告)号:ES2061447T3
公开(公告)日:1994-12-16
申请号:ES87103938
申请日:1987-03-18
Applicant: HOECHST AG
Inventor: HOCK FRANZ DR , SCHOLTHOLT JOSEF PROF DR , URBACH HANSJORG DR , HENNING RAINER DR , LERCH ULRICH DR , NICKEL WOLF-ULRICH DR , RUGER WOLFGANG DR
IPC: C07K14/81 , A61K38/00 , A61P9/12 , A61P25/28 , C07C235/02 , C07K1/06 , C07K1/113 , C07K5/02 , C07K5/06 , A61K37/02 , A61K37/64
Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.
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公开(公告)号:CS8906519A3
公开(公告)日:1992-05-13
申请号:CS651989
申请日:1987-03-27
Applicant: HOECHST AG
Inventor: HOCK FRANZ DR , SCHOLTHOLT JOSEF PROF DR , URBACH HANSJORG DR , HENNING RAINER DR , LERCH ULRICH DR , NICKEL WOLF-ULRICH DR , RUGER WOLFGANG DR
IPC: C07K14/81 , A61K38/00 , A61P9/12 , A61P25/28 , C07C235/02 , C07K1/06 , C07K1/113 , C07K5/02 , C07K5/06 , C07C103/50 , C07C103/68
CPC classification number: C07K5/0222 , A61K38/00
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公开(公告)号:CS8702126A3
公开(公告)日:1992-04-15
申请号:CS212687
申请日:1987-03-27
Applicant: HOECHST AG
Inventor: HOCK FRANZ DR , SCHOLTHOLT JOSEF PROF DR , URBACH HANSJORG DR , HENNING RAINER DR , LERCH ULRICH DR , NICKEL WOLF-ULRICH DR , RUGER WOLFGANG DR
IPC: C07K14/81 , A61K38/00 , A61P9/12 , A61P25/28 , C07C235/02 , C07K1/06 , C07K1/113 , C07K5/02 , C07K5/06 , C07C233/50 , C07C233/68
CPC classification number: C07K5/0222 , A61K38/00
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公开(公告)号:ES2059688T3
公开(公告)日:1994-11-16
申请号:ES89122794
申请日:1989-12-11
Applicant: HOECHST AG
Inventor: RUGER WOLFGANG DR , URBACH HANSJORG DR , RUPPERT DIETER DR , SCHOLKENS BERNWARD DR
IPC: A61K31/16 , A61K31/33 , A61K31/415 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4412 , A61K31/4418 , A61K38/00 , A61K38/55 , A61P9/12 , A61P31/12 , A61P43/00 , C07C291/02 , C07D213/81 , C07D233/64 , C07D295/18 , C07D333/24 , C07D521/00 , C07K1/113 , C07K5/02 , C07K5/06 , C07K5/065 , C07K14/81 , A61K37/64
Abstract: The present invention relates to compounds of the general formula I (I) in which A denotes a radical from the group comprising S, SO, SO2, O, CO, CS or a direct bond, B denotes the radical of an amino acid and D denotes a CH2 group or a radical -NR7-, where R7 can be hydrogen or a (C1-C4)alkyl radical; and in which R1 to R4 are defined as indicated in the description, to a process for the preparation thereof, to agents containing these, and to the use thereof.
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公开(公告)号:ES2043626T3
公开(公告)日:1994-01-01
申请号:ES87114164
申请日:1987-09-29
Applicant: HOECHST AG
Inventor: BECKER REINHARD DR , HENNING RAINER DR , RUGER WOLFGANG DR , TEETZ WOLFGANG DR , URBACH HANSJORG DR
IPC: A61K31/40 , A61K31/401 , A61K31/435 , A61K31/44 , A61K38/05 , A61K38/55 , A61K45/06 , A61P3/00 , A61P3/14 , A61P9/12 , A61P43/00 , A61K37/64
Abstract: The combinations are produced as described and used as medicines.
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公开(公告)号:CS651989A3
公开(公告)日:1992-05-13
申请号:CS651989
申请日:1987-03-27
Applicant: HOECHST AG
Inventor: HOCK FRANZ DR , SCHOLTHOLT JOSEF PROF DR , URBACH HANSJORG DR , HENNING RAINER DR , LERCH ULRICH DR , NICKEL WOLF-ULRICH DR , RUGER WOLFGANG DR
IPC: C07K14/81 , A61K38/00 , A61P9/12 , A61P25/28 , C07C235/02 , C07K1/06 , C07K1/113 , C07K5/02 , C07K5/06 , C07C103/50 , C07C103/68
Abstract: The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.
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