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21.发明专利
公开(公告)号：AU2017225758A1
公开(公告)日：2018-08-30
申请号：AU2017225758
申请日：2017-03-02
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MAHALAKSHMI , FARACE GIOSI , QUINN JOHN JOSEPH , YERRAMILLI MURTHY V S N
Abstract: The disclosure provides compositions and methods for the detection of renal disease and periodontal disease in mammals.
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公开(公告)号：AU2016254226A1
公开(公告)日：2017-11-09
申请号：AU2016254226
申请日：2016-05-02
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MAHALAKSHMI , OBARE EDWARD , QUINN JOHN JOSEPH , YERRAMILLI MURTHY VSN
IPC: G01N33/48 , C07C229/08 , C07C279/12 , G01N33/50 , G01N33/68
Abstract: Methods for determining renal function in an animal subject, the method including measuring the concentration of β-aminoisobutyric acid (β-amino isobutyrate) (BAIB) in patients samples and determining the presence, likelihood, or progression of kidney disease as a result of structural damage, or mortality associated with kidney disease. The methods also include measuring the concentration of BAIB in combination is symmetrical dimethyl arginine (SDMA) and determining kidney disease based upon the concentrations of BAIB and SDMA in the samples. Anti-BAIB antibodies, BAIB-conjugates, and assay methods using the antibodies and conjugates are also disclosed.
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公开(公告)号：AU2012262154B2
公开(公告)日：2016-08-04
申请号：AU2012262154
申请日：2012-05-31
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MURTHY V S N , YERRAMILLI MAHALAKSHMI , ATKINSON MICHAEL
IPC: G01N33/53
Abstract: A method for determining the amount of NT-proBNP in blood samples from felines. The method includes detecting degradation products of feline NT-proBNP by various methods, including using antibodies, kits and devices.
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公开(公告)号：AU2011261308C1
公开(公告)日：2016-02-18
申请号：AU2011261308
申请日：2011-06-03
Applicant: IDEXX LAB INC
IPC: G01N33/68 , C07K14/00 , C07K14/775 , G01N33/53
Abstract: This invention provides reagents and methods for diagnosing renal disease. Differential levels of inosine metabolite, and proteins: apolipoprotein C-I, apolipoprotein C-II, fibrinogen alpha chain, or fibrinogen A-alpha chain, kininogen, Inter-Alpha Inhibitor H4 (ITIH4), keratin Type I cytoskeletol 10 cystatin A, cystatin B and other polypeptides and fragments thereof provide biomarkers of renal disease and are described herein.
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公开(公告)号：CA2923140A1
公开(公告)日：2015-03-12
申请号：CA2923140
申请日：2014-09-05
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MAHALAKSHMI , YERRAMILLI MURTHY V S N
Abstract: The disclosure is directed to methods and apparatus for the determination, diagnosis, progression and prognosis of kidney disease and mortality associated with kidney disease. The disclosure includes a method for determining renal function, in particular estimating glomerular filtration rate (GFR), in an animal. GFR can be useful in the diagnosis and treatment of kidney disease or dysfunction. In various aspects, the disclosure is directed to the use of free symmetrical dimethylarginine (SDMA) and creatinine in blood samples from animals, in particular cats and dogs, to determine glomerular filtration rate and kidney disease.
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Patent Agency Ranking
公开(公告)号：CA2856798A1
公开(公告)日：2012-12-06
申请号：CA2856798
申请日：2012-05-31
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MURTHY V S N , YERRAMILLI MAHALAKSHMI , ATKINSON MICHAEL
IPC: G01N33/48 , G01N33/483 , G01N33/53 , G01N33/577
Abstract: A method for determining the amount of NT-proBNP in blood samples from felines. The method includes detecting degradation products of feline NT-proBNP by various methods, including using antibodies, kits and devices.
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公开(公告)号：CA2807240A1
公开(公告)日：2012-02-09
申请号：CA2807240
申请日：2011-08-04
Applicant: IDEXX LAB INC
Abstract: A method for determining the amount of NT-proBNP in blood samples from animals. The method includes detecting degradation products of NT-proBNP by various methods, including using antibodies, kits and device.
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公开(公告)号：MX383274B
公开(公告)日：2025-03-13
申请号：MX2016002922
申请日：2016-03-04
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MAHALAKSHMI , YERRAMILLI MURTHY V S N
Abstract: La presente invención se refiere a métodos y aparatos para la determinación, diagnóstico, progreso y pronóstico de la enfermedad renal y mortalidad asociada con la enfermedad renal. La descripción incluye un método para determinar la función renal, en particular estimar velocidad de filtración glomerular (GFR), en un animal. La GFR puede ser útil en el diagnóstico y tratamiento de la enfermedad o disfunción renal. En varios aspectos, la descripción se dirige al uso de dimetilarginina simétrica libre (SDMA) y creatinina en muestras de sangre de animales, en particular gatos y perros, para determinar la velocidad de filtración glomerular y enfermedad renal.
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公开(公告)号：AU2023306240A1
公开(公告)日：2025-01-30
申请号：AU2023306240
申请日：2023-07-15
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MURTHY , YERRAMILLI MAHALAKSHMI , OBARE EDWARD , PATCH DANIEL
Abstract: Methods and devices for determining the hematocrit of blood samples.
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30.发明专利
公开(公告)号：NZ745263A
公开(公告)日：2022-07-01
申请号：NZ74526317
申请日：2017-03-02
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MAHALAKSHMI , YERRAMILLI MURTHY , FARACE GIOSI , QUINN JOHN
Abstract: The disclosure provides use of one or more antibodies that specifically bind one or more polypeptides consisting of SEQ ID NOs:2, 3, 5, 6, 7, 11, or 12, in manufacture of an agent for detecting cystatin B polypeptides in a sample by a method comprising contacting the sample with the one or more antibodies, under conditions suitable for formation of complexes of the cystatin B polypeptides and the one or more antibodies, and detecting the complexes of cystatin B polypeptides and the one or more antibodies.
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