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21.发明专利
公开(公告)号：CA2200061A1
公开(公告)日：1996-03-21
申请号：CA2200061
申请日：1995-07-26
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , MATSUNAGA TERRY , YELLOWHAIR DAVID
IPC: G01R33/28 , A61B5/055 , A61J1/00 , A61K8/04 , A61K8/14 , A61K8/70 , A61K9/127 , A61K9/133 , A61K41/00 , A61K47/48 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B65D81/20
Abstract: A container comprising an aqueous lipid suspension and a gaseous phase substantially separate from the aqueous stabilizing phase, useful in diagnostic imaging such as ultrasound and magnetic resonance imaging and in therapeutic applications, is disclosed.
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公开(公告)号：DK0711127T4
公开(公告)日：2009-03-16
申请号：DK94919184
申请日：1994-05-19
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , MATSUNAGA TERRY , WU GUANLI , FRITZ THOMAS A , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K48/00 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02
Abstract: Methods of and apparatus for preparing gas-filled liposomes are described. Gas-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号：ES2207687T3
公开(公告)日：2004-06-01
申请号：ES96938613
申请日：1996-06-06
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , MCCREERY THOMAS , YELLOWHAIR DAVID , BARRETTE TERRENCE R
IPC: A61B5/055 , A61B8/00 , A61K49/00 , A61J3/00 , A61K8/14 , A61K8/70 , A61K9/127 , A61K41/00 , A61K47/48 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01F3/04 , B01F11/00 , B01F15/00
Abstract: A method and apparatus for making vesicles suitable for use as contrast agents in which a container containing an aqueous suspension phase and a separate gas phase is shaken using reciprocating motion. The reciprocating motion is produced by a shaker arm that moves the container in two, substantially perpendicular directions, with the motion in the first direction being along an arcuate path. The overall path of the motion occurs in a figure-8 eight pattern. The frequency of shaking is at least approximately 2800 RPM, the length of the shaker arm is at least approximately 6 cm, and the angle through which the shaker arm rotates in the first direction is at least approximately 3 DEG . The total length of travel around the figure-8 pattern is at least 0.7 cm.
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公开(公告)号：DE69431753T2
公开(公告)日：2003-07-03
申请号：DE69431753
申请日：1994-05-19
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K48/00 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02
Abstract: Methods of and apparatus for preparing gas-filled liposomes are described. Gas-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号：DK0711127T3
公开(公告)日：2003-03-17
申请号：DK94919184
申请日：1994-05-19
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K48/00 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02
Abstract: Methods of and apparatus for preparing gas-filled liposomes are described. Gas-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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Patent Agency Ranking
公开(公告)号：AT233574T
公开(公告)日：2003-03-15
申请号：AT94919208
申请日：1994-05-20
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02
Abstract: Methods of and apparatus for preparing temperature activated gaseous precursor-filled liposomes are described. Gaseous precursor-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号：AU732440B2
公开(公告)日：2001-04-26
申请号：AU8840698
申请日：1998-10-09
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
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公开(公告)号：HK1028943A1
公开(公告)日：2001-03-16
申请号：HK99105053
申请日：1999-11-04
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , FRITZ THOMAS A , MATXUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K48/00 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02 , A61K
Abstract: Methods of and apparatus for preparing gas-filled liposomes are described. Gas-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号：AU684088B2
公开(公告)日：1997-12-04
申请号：AU7094894
申请日：1994-05-19
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
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公开(公告)号：DK0788348T3
公开(公告)日：2004-11-29
申请号：DK95927429
申请日：1995-07-26
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , MATSUNAGA TERRY O , YELLOWHAIR DAVID
IPC: G01R33/28 , A61B5/055 , A61J1/00 , A61K8/04 , A61K8/14 , A61K8/70 , A61K9/127 , A61K9/133 , A61K41/00 , A61K47/48 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B65D81/20
Abstract: A container comprising an aqueous lipid suspension and a gaseous phase substantially separate from the aqueous stabilizing phase, useful in diagnostic imaging such as ultrasound and magnetic resonance imaging and in therapeutic applications, is disclosed.
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