公开(公告)号：KR1020140009854A

公开(公告)日：2014-01-23

申请号：KR1020120076803

申请日：2012-07-13

Applicant: 삼성전자주식회사

Inventor： 안태진 ,  무크헤르지수브한카르 ,  홍석진 ,  말라바라푸라마스리칸쓰 ,  손대순 ,  이천희 ,  보파르디카시암선더아지트

IPC: C12Q1/68 ,  G06F19/26 ,  G01N33/15

CPC classification number: G06F19/12 ,  G01N33/15 ,  G06F19/26

Abstract: The present invention relates to a method and a device for analyzing gene information for treatment decision which obtains information regarding a gene network for categorizing genes in a genome of an individual into multiple sub groups by the functional correlation of the genes, and visualizes the sub groups corresponding to the action of at least one medicine. [Reference numerals] (10) Gene information analyzing device; (110) Data obtaining unit; (120) Sub group extracting unit; (130) Index generating unit; (140) Visualization processing unit; (20) Drug list; (AA) Gene network

Abstract translation: 本发明涉及一种用于分析用于治疗决定的基因信息的方法和装置，其通过基因的功能相关性获得关于将个体基因组中的基因分为多个亚组的基因网络的信息，并且可视化子组 对应于至少一种药物的作用。 （附图标记）（10）基因信息分析装置; （110）数据获取单元; （120）子组提取单元; （130）指标生成单元; （140）可视化处理单元; （20）药物清单; （AA）基因网络

公开(公告)号：KR1020120098336A

公开(公告)日：2012-09-05

申请号：KR1020110018211

申请日：2011-02-28

Applicant: 삼성전자주식회사

Inventor： 안태진 ,  김수현 ,  우경구

IPC: G01N33/53 ,  G06F19/18 ,  G06F17/10 ,  C12Q1/68

CPC classification number: G06F19/16 ,  G06F19/18

Abstract: PURPOSE: A method for identifying target biomolecules by probe binding frequency is provided to effectively and accurately identify the target biomelecules in a sample. CONSTITUTION: A method for identifying target biomolecules comprises: a step of providing N number of probe molecules which bind to target biomolecule and contain each different members; a step of binding N number of probe molecules to target biomolecule to generate a target signature; a step of binding N number of probe molecules to known reference biomolecule which is allogenic with the target biomolecule to generate reference signature; and a step of identifying the target biomolecules according to the consistency degree of the target signature and reference signature. The biomolecule is peptide molecules including nucleic acid molecules or amino acids. [Reference numerals] (AA, BB) Probe; (CC) Target biomolecule

Abstract translation: 目的：提供通过探针结合频率鉴定目标生物分子的方法，以有效和准确地鉴定样品中的目标生物分子。 构成：用于鉴定靶生物分子的方法包括：提供N个与目标生物分子结合并包含每个不同成员的探针分子的步骤; 将N个探针分子与目标生物分子结合以产生目标标记的步骤; 将N个探针分子与目标生物分子同种异体的已知参考生物分子结合以产生参考标记的步骤; 以及根据目标签名和参考签名的一致性来识别目标生物分子的步骤。 生物分子是包括核酸分子或氨基酸的肽分子。 （附图标记）（AA，BB）探头; （CC）靶生物分子

公开(公告)号：KR101138867B1

公开(公告)日：2012-05-14

申请号：KR1020050051119

申请日：2005-06-14

Applicant: 삼성전자주식회사

Inventor： 김민선 ,  홍성우 ,  김재흡 ,  이연수 ,  김기은 ,  안태진

IPC: C12Q1/68 ,  C12N15/12

CPC classification number: C12Q1/6886 ,  C12Q2600/172

Abstract: Provided are a polynucleotide for diagnosis or treatment of colorectal cancer including at least 10 contiguous nucleotides of a nucleotide sequence selected from the group consisting of nucleotide sequences of SEQ ID NOS: 1 and 2 and including a nucleotide at position 101 of the nucleotide sequence, or the complement thereof; a microarray having a substrate on which the polynucleotide is immobilized; a diagnostic kit for the detection of colorectal cancer including the polynucleotide; and a method of detecting colorectal cancer using the polynucleotide.

公开(公告)号：KR101138862B1

公开(公告)日：2012-05-14

申请号：KR1020050012038

申请日：2005-02-14

Applicant: 삼성전자주식회사

Inventor： 이연수 ,  박경희 ,  김재흡 ,  이규상 ,  박연아 ,  조지영 ,  송옥렬 ,  안태진 ,  손옥경

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/156

Abstract: Provided is a polynucleotide for diagnosis or treatment of breast cancer, including at least 10 contiguous nucleotides of a nucleotide sequence selected from the group consisting of nucleotide sequences of SEQ ID No: 1 to SEQ ID No: 5 and comprising a nucleotide at 101st position of the nucleotide sequence, or a complementary polynucleotide thereof.

公开(公告)号：KR100878895B1

公开(公告)日：2009-01-15

申请号：KR1020070013060

申请日：2007-02-08

Applicant: 삼성전자주식회사

Inventor： 박태준 ,  안태진 ,  정태철

IPC: H04W88/02 ,  G06F15/00 ,  H04B1/40

CPC classification number: Y02D70/40

Abstract: 본 발명은 휴대단말 악성코드 처리 시스템에 관한 것으로, 휴대단말에 탑재되는 악성코드 처리장치와 중앙처리센터 간의 상호협력을 통한 악성코드 검출 시스템을 구성하는 것을 특징으로 한다. 특히 휴대단말에 해를 끼칠 악성코드로 의심되는 정보(프로그램 또는 데이터를 포함)를 검출하는 1차 검출 과정과, 1차 검출된 악성코드로 의심되는 정보가 실제로 악성코드인지를 확인하는 2차 검출 과정을 포함하는 2단계의 검출과정을 구현한 휴대단말 악성코드 처리 시스템이 제공된다. 이에 따라 검출 정확도를 높이면서 휴대단말의 CPU, 메모리, 배터리 오버헤드를 절감하고 통신 오버헤드를 줄일 수 있다.
악성코드, malware, 바이러스, 검출

Abstract translation: 提供了一种用于在移动终端中处理恶意软件的装置和方法，其主要是通过最小化CPU，存储器和通信开销来降低电池消耗，而不降低恶意软件检测性能。 第一检测器（12）通过分析输入到移动终端的信息来检测怀疑是恶意软件的信息。 第二检测器（14）通过有线/无线网络从与移动终端连接的中央处理中心接收到用于验证恶意软件所需的信息，来验证检测到的可疑信息是否为恶意软件。 显示单元显示第一检测器的检测结果和/或第二检测器的验证结果。 中央处理单元包括存储用于验证恶意软件所需的信息和处理器的数据库。 处理器从移动终端接收被怀疑为恶意软件的信息，通过参考数据库提取用于确定接收到的可疑信息是否对应于恶意软件的验证所需的信息，并将提取的信息发送到移动终端。

公开(公告)号：KR1020080071862A

公开(公告)日：2008-08-05

申请号：KR1020070010300

申请日：2007-01-31

Applicant: 삼성전자주식회사

Inventor： 안태진 ,  박태준 ,  정태철

IPC: G06F11/00

CPC classification number: G06F21/56 ,  G06F21/564

Abstract: A device and a method for detecting an intrusion code are provided to generate a customized immune database capable of determining the intrusion code, prevent damage caused by new or mutated malicious codes with the customized immune database, and obtain a diagnostic for the new or mutated malicious codes from a system having immunity to the new or mutated malicious codes. A setting value input unit(110) receives setting values customized to each group. An immune database generator(120) generates an immune database(140) based on the setting values. An intrusion code determiner(130) determines whether input data is an intrusion code based on the immune database. The setting value input unit receives a group feature key, a resident code list, and a random pool generation factor. The immune database generator includes a feature extractor extracting features of resident codes by using the group feature key, a pool feature generator generating random pool features based on the group feature key and the random pool generation factor, a similarity calculator calculating similarity between the features of the resident codes and the random pools, and an immune database generation manager generating the immune database from the features having the similarity under a threshold.

Abstract translation: 提供了用于检测入侵码的设备和方法，以产生能够确定入侵代码的定制免疫数据库，防止由定制的免疫数据库引起的新的或突变的恶意代码造成的损害，并且获得针对新的或突变的恶意的诊断 来自具有对新的或突变的恶意代码具有豁免性的系统的代码。 设置值输入单元（110）接收针对每个组定制的设置值。 免疫数据库生成器（120）基于设置值生成免疫数据库（140）。 入侵码确定器（130）确定输入数据是否是基于免疫数据库的入侵码。 设置值输入单元接收组特征密钥，驻留码列表和随机池生成因子。 免疫数据库生成器包括通过使用组特征密钥提取驻留码的特征的特征提取器，基于组特征密钥和随机池生成因子生成随机池特征的池特征生成器，计算相似度的相似度计算器 驻留码和随机池，以及免疫数据库生成管理器，从阈值下具有相似性的特征生成免疫数据库。

公开(公告)号：KR1020080058021A

公开(公告)日：2008-06-25

申请号：KR1020060132041

申请日：2006-12-21

Applicant: 삼성전자주식회사

Inventor： 안태진 ,  김병철 ,  이규상

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q1/6837 ,  G01N33/57423

Abstract: A marker is provided to diagnose lymph node micrometastasis of lung cancer from a trace amount of biopsy at an early stage, thereby being utilized to an early diagnosis of the lung cancer and also used as a marker for detecting the micrometastasis from blood and bone marrow as well as lung. A marker for diagnosing lymph node micrometastasis of lung cancer comprises at least one polynucleotide. A kit for diagnosing lymph node micrometastasis of lung cancer comprises a sense and an anti-sense primers of the at least one of the polynucleotide described in the table 3. A microarray for diagnosing lymph node micrometastasis of lung cancer comprises the marker or an antibody recognizing a protein encoded by the marker. A method for diagnosing lymph node micrometastasis of lung cancer comprises the steps of: (a) obtaining a lung cancer sample from a lung cancer patient; (b) detecting expression or activity of the polynucleotide from the sample; and (c) diagnosing the lymph node micrometastasis of the lung cancer based on the detection result.

Abstract translation: 提供了一种标记，用于从早期的微量活检中诊断肺癌的淋巴结微转移，从而用于肺癌的早期诊断，也用作检测血液和骨髓微转移的标志物 好肺。 用于诊断肺癌淋巴结微转移的标记物包含至少一种多核苷酸。 用于诊断肺癌淋巴结微转移的试剂盒包括表3中描述的至少一种多核苷酸的有义和反义引物。用于诊断肺癌淋巴结微转移的微阵列包括标记或识别抗体的抗体 由标记编码的蛋白质。 用于诊断肺癌淋巴结微转移的方法包括以下步骤：（a）从肺癌患者获得肺癌样品; （b）从样品中检测多核苷酸的表达或活性; （c）根据检测结果诊断肺癌的淋巴结微转移。

公开(公告)号：KR1020080029726A

公开(公告)日：2008-04-03

申请号：KR1020070007628

申请日：2007-01-24

Applicant: 삼성전자주식회사

Inventor： 오지영 ,  이연수 ,  백상현 ,  김병철 ,  김숙영 ,  박경희 ,  이정남 ,  정종석 ,  김아기 ,  이묘용 ,  안태진

IPC: C12Q1/68

CPC classification number: C12Q1/689 ,  C12Q2600/16 ,  C12Q1/6837

Abstract: A primer set is provided to amplify a resistance donating gene from antibiotics resistant bacteria. A probe set is provided to be specifically coupled to a target sequence existing in a PCR product amplified by the primer set, thereby being used for detecting at least one bacteria with the antibiotics resistance. A microarray is provided to be used for detecting the bacteria with antibiotics resistance. An oligonucleotide primer set for amplifying at least one selected from the group consisting of aataph, ant, aph, CMY1, CMY2, CTX1, CTX2, DHA, IMP, OXA, PER, SHV, TEM, VIM, ermA, ermB, ermC, mef, mecA, Spn pbp2b, Pae gyrA, Sau gyrA, Sau parC, Sau parE, vanA, and vanB is selected from the group consisting of: an oligonucleotide set including at least one oligonucleotide selected from oligonucleotides consisting of more than 10 consecutive nucleotide fragments in SEQ ID : NOs. 1 and 2; SEQ ID : NOs. 3 and 4; SEQ ID : NOs. 5 and 6; SEQ ID : NOs. 7 and 8; SEQ ID : NOs. 9 and 10; SEQ ID : NOs. 11 and 12; SEQ ID : NOs. 13 and 14; SEQ ID : NOs. 15 and 16; SEQ ID : NOs. 17 and 18; SEQ ID : NOs. 19 and 20; SEQ ID : NOs. 21 and 22; SEQ ID : NOs. 23 and 24; SEQ ID : NOs. 25 and 26; SEQ ID : NOs. 27 and 28; SEQ ID : NOs. 29 and 30; SEQ ID : NOs. 31 and 32; SEQ ID : NOs. 33 and 34; SEQ ID : NOs. 35 and 36; SEQ ID : NOs. 37 and 38; SEQ ID : NOs. 39 and 40; SEQ ID : NOs. 41 and 42; SEQ ID : NOs. 43 and 44; SEQ ID : NOs. 45 and 46; SEQ ID : NOs. 47 and 48; SEQ ID : NOs. 49 and 50; and SEQ ID : NOs. 51 and 52. A method for detecting the presence of bacteria having resistance against at least one antibiotics selected from the group consisting of aminoglycoside, beta-lactam, erythromycin, methicillin, vancomycin and quinolone-based antibiotics comprises the steps of: (a) contacting a sample with at least one oligonucleotide probe or oligonucleotide probe set to hybridize a target sequence in the sample with a probe sequence; and (b) detecting the hybridization degree between the probe and the target sequence in the sample. A kit for detecting the existence of the antibiotics resistant bacteria comprises the primer set and an instruction manual.

Abstract translation: 提供了一个引物组来扩增来自抗生素抗性细菌的抗性供体基因。 提供探针组以特异性偶联于存在于由引物组扩增的PCR产物中的靶序列，从而用于检测至少一种具有抗生素抗性的细菌。 提供微阵列用于检测抗生素抗性的细菌。 用于扩增选自由aataph，ant，aph，CMY1，CMY2，CTX1，CTX2，DHA，IMP，OXA，PER，SHV，TEM，VIM，ermA，ermB，ermC，mef中的至少一种的寡核苷酸引物组 ，mecA，Spn pbp2b，Pae gyrA，Sau gyrA，Sau parC，Sau parE，vanA和vanB选自：包含至少一种寡核苷酸组的寡核苷酸组，所述寡核苷酸组选自寡核苷酸，所述寡核苷酸由超过10个连续核苷酸片段组成， SEQ ID：NO。 1和2; SEQ ID：NO。 3和4; SEQ ID：NO。 5和6; SEQ ID：NO。 7和8; SEQ ID：NO。 9和10; SEQ ID：NO。 11和12; SEQ ID：NO。 13和14; SEQ ID：NO。 15和16; SEQ ID：NO。 17和18; SEQ ID：NO。 19和20; SEQ ID：NO。 21和22; SEQ ID：NO。 23和24; SEQ ID：NO。 25和26; SEQ ID：NO。 27和28; SEQ ID：NO。 29和30; SEQ ID：NO。 31和32; SEQ ID：NO。 33和34; SEQ ID：NO。 35和36; SEQ ID：NO。 37和38; SEQ ID：NO。 39和40; SEQ ID：NO。 41和42; SEQ ID：NO。 43和44; SEQ ID：NO。 45和46; SEQ ID：NO。 47和48; SEQ ID：NO。 49和50; 和SEQ ID NO： 一种用于检测对至少一种选自氨基糖苷，β-内酰胺，红霉素，甲氧西林，万古霉素和喹诺酮类抗生素的抗生素具有抗性的细菌的存在的方法包括以下步骤：（a） 设置有至少一个寡核苷酸探针或寡核苷酸探针的样品与样品中的靶序列与探针序列杂交; 和（b）检测样品中探针与目标序列之间的杂交度。 用于检测抗生素抗性细菌存在的试剂盒包括引物组和使用说明书。

公开(公告)号：KR100763902B1

公开(公告)日：2007-10-05

申请号：KR1020050009487

申请日：2005-02-02

Applicant: 삼성전자주식회사

Inventor： 이연수 ,  박종훈 ,  박경희 ,  안태진

IPC: C07K14/47 ,  C12Q1/68 ,  G01N33/53

Abstract: 본 발명은 서열번호 4의 아미노산 서열을 갖고, 세포자가사 (apoptosis)를 유도하는 활성을 갖는 분리된 단백질, 및 그를 코딩하는 유전자를 제공한다. 또한, 상기 유전자 또는 그 단편이 고정화되어 있는 기판을 갖는 마이크로어레이를 제공한다. 또한, 본 발명은 상기 단백질에 특이적으로 결합하는 항체를 이용하여 유방암을 진단하는 방법 또는 세포 내에서 상기 유전자의 발현 유무를 결정하여 유방암을 진단하는 방법을 제공한다.
SNP, BCRP 유전자, 유방암, 막단백질, 세포자가사

公开(公告)号：KR1020060134787A

公开(公告)日：2006-12-28

申请号：KR1020060029071

申请日：2006-03-30

Applicant: 삼성전자주식회사

Inventor： 김병철 ,  박경희 ,  안태진 ,  이규상 ,  김재흡 ,  김기은 ,  이연수

IPC: C07H21/00 ,  C12N15/00 ,  C12Q1/68

CPC classification number: C07K14/4702 ,  C12N15/113 ,  C12N2310/11 ,  C12Q1/6883 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/172 ,  C12Q1/6837

Abstract: A myocardial infarction related single nucleotide polymorphism and a haplotype thereof are provided to be able to predict the attack probability of the myocardial infarction and genetic sensitivity, thereby being used for diagnosing the myocardial infarction and screening medicines for treating the myocardial infarction. The myocardial infarction related single nucleotide polymorphism comprises a polynucleotide including at least 8 continuous polynucleotides containing each 101th nucleotide in a polynucleotide selected from the group consisting of SEQ ID : NOs. 1-7, 9, 10 and 14, and a complimentary polynucleotide thereof. The method for identifying a subject having a modified danger degree of myocardial infarction attack comprises the steps of: (a) isolating a nucleic acid sample from the subject to de diagnosed; and (b) determining a genotype of a polymorphic site of the each 101th nucleotide in the polynucleotide selected from the group consisting of SEQ ID : NOs. 1-7, 9, 10 and 14 or a polynucleotide consisting of SEQ ID : NOs. 1-14.

Abstract translation: 提供心肌梗死相关单核苷酸多态性及其单体型，以能够预测心肌梗死的发病概率和遗传敏感性，从而用于诊断心肌梗死并筛选用于治疗心肌梗死的药物。 心肌梗塞相关的单核苷酸多态性包括多核苷酸，其包含至少8个连续多核苷酸，其含有选自SEQ ID NO：1的多核苷酸中的每个第101位核苷酸。 1-7,9,10和14及其互补多核苷酸。 用于鉴定具有改变的心肌梗塞危险程度的受试者的方法包括以下步骤：（a）将来自受试者的核酸样品分离成诊断; 和（b）确定选自SEQ ID：NO的多核苷酸中的每个第101个核苷酸的多态性位点的基因型。 1-7,9,10和14或由SEQ ID NO： 1-14。