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    식품 및 식품 포장제 중의 비스페놀-에이 검출법
    31.
    发明授权
    식품 및 식품 포장제 중의 비스페놀-에이 검출법 失效
    식품및식품포장제중의비스페놀 - 에이검출법

    公开(公告)号：KR100379757B1

    公开(公告)日：2003-04-11

    申请号：KR1020000071402

    申请日：2000-11-28

    Applicant: 한국과학기술연구원

    Inventor： 명승운 ,  김명수 ,  김세진 ,  김기철

    IPC: G01N30/72

    Abstract: PURPOSE: Provided is a detection method of bisphenol-A among foods or foods packing material which shows selective and superior sensitivity for gas chromatography(GC) or GC/mass spectrometer so that it provides optimal analysis condition for the GC/mass spectrometer. CONSTITUTION: The detection method of bisphenol-A among the foods or the foods packing material comprises the steps of: (i) extracting bisphenol-A from the foods or the foods packing material in organic solvent and treating in sodium hydroxide; (ii) reacting with 100-1400μl of anhydrous acetic acid at 25-100deg.C for 5-20 minutes to produce derivatives of bisphenol-A; and (iii) analyzing concentration of bisphenol-A at the GC or the GC/mass spectrometer.

    Abstract translation: 用途：本发明提供一种食品或食品包装材料中的双酚A检测方法，其对气相色谱（GC）或GC /质谱仪显示选择性和优异的灵敏度，从而为GC /质谱仪提供最佳分析条件。 构成：在食品或食品包装材料中检测双酚A的方法包括以下步骤：（i）从食品或食品包装材料中用有机溶剂提取双酚-A并用氢氧化钠处理; （ii）在25-100℃与100-1400μl无水乙酸反应5-20分钟以产生双酚-A衍生物; 和（iii）分析GC或GC /质谱仪处双酚A的浓度。

    이고들빼기로부터 분리한 화합물을 유효성분으로 함유하는 간 기능 개선용 약학적 조성물 및 간 기능 개선용 건강기능 식품조성물
    33.
    发明公开
    이고들빼기로부터 분리한 화합물을 유효성분으로 함유하는 간 기능 개선용 약학적 조성물 및 간 기능 개선용 건강기능 식품조성물 有权
    药物组合物和健康功能食品组合物，用于改善含有从作为活性成分的青IA素分离的化合物的肝脏功能

    公开(公告)号：KR1020120031041A

    公开(公告)日：2012-03-29

    申请号：KR1020120024051

    申请日：2012-03-08

    Applicant: 한국과학기술연구원

    Inventor： 노주원 ,  이샛별 ,  윤지호 ,  정상훈 ,  이희주 ,  강경수 ,  유지혜 ,  김명수 ,  안수용 ,  김종환

    IPC: A61K31/7042 ,  A61K31/704 ,  A61K36/28 ,  A61P1/16

    CPC classification number: A61K36/28 ,  A61K31/222 ,  A61K31/7028

    Abstract: PURPOSE: A pharmaceutical composition and a health supplement for liver function improvement containing a compound isolated from youngia denticulata as an active ingredient are provided to increase activity of detoxification enzyme of liver including Quinone reductase and Antioxidant response element. CONSTITUTION: A pharmaceutical composition and a health supplement for liver function improvement containing a compound isolated from youngia denticulata as an active ingredient comprises a compound which is represented by chemical formula 3,4, or 5 as active ingredients. The compound of chemical formula 3,4, or 5 is Youngiaside A, Youngiaside B, and Youngiaside C. A health supplement composition for liver function improvement comprises compound of the chemical formulas of 3,4, or 5. The compound of chemical formula 3, 4, or 5 detoxifies carcinogenic materials by multiplying activity of quinone reductase. The compound of chemical formula 3, 4, or 5 also detoxifies carcinogenic materials by multiplying activity of the oxygen-resistant response factor(ARE) which induces activity of 2 phase detoxifying enzyme system.

    Abstract translation: 目的：提供一种药物组合物和肝脏功能改善的健康补充剂，其含有从幼牙牙齿中分离的化合物作为活性成分，以增加肝脏的解毒酶的活性，包括醌类还原酶和抗氧化剂反应元件。 构成：含有从幼齿牙齿中分离出的化合物作为活性成分的肝功能改善的药物组合物和健康补充剂包括由化学式3,4或5表示的化合物作为活性成分。 化学式3,4或5的化合物是亚氨基酸A，亚氨基二乙酸和亚油酸酯C.用于肝功能改善的健康补充剂组合物包括化学式为3,4或5的化合物。化学式3的化合物 ，4或5通过增加醌还原酶的活性来解毒致癌物质。 化学式3,4或5的化合物还通过增加诱导2相解毒酶体系活性的耐氧反应因子（ARE）的活性来对致癌物质进行解毒。

    이고들빼기 추출물, 이의 분획물 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 간 기능 개선용 약학적 조성물 및 간 기능 개선용 건강기능 식품조성물
    34.
    发明公开
    이고들빼기 추출물, 이의 분획물 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 간 기능 개선용 약학적 조성물 및 간 기능 개선용 건강기능 식품조성물 有权
    药物组合物和健康功能食品组合物，用于改善含有青蒿素提取物的肝脏功能，其分离或其分离的化合物作为活性成分

    公开(公告)号：KR1020100091131A

    公开(公告)日：2010-08-18

    申请号：KR1020100011969

    申请日：2010-02-09

    Applicant: 한국과학기술연구원

    Inventor： 노주원 ,  이샛별 ,  윤지호 ,  정상훈 ,  이희주 ,  강경수 ,  유지혜 ,  김명수 ,  안수용 ,  김종환

    IPC: A61K36/28 ,  A61K31/222 ,  A61K31/7028 ,  A61P35/00

    CPC classification number: A61K36/28 ,  A61K31/222 ,  A61K31/7028

    Abstract: PURPOSE: A composition containing Youngia denticulate extract or compound isolated from the same are provided to induce activation of quinone reductase(QR) and to improve liver function. CONSTITUTION: A pharmaceutical composition for preventing cancer contains Youngia denticulate extract as an active ingredient, which is isolated using water, organic solvent or mixture solvent thereof. An organic solvent is alcohol of C1-C4, acetic acid ethyl, methylene chloride, or chloroform. The Youngia denticulate extract detoxifies carcinogen by enhancing quinone reductase activation. A pharmaceutical composition for preventing cancer contains Youngia denticulate fraction as an active ingredient. The Youngia denticulate fraction is obtained by frequently fractioning Youngia denticulate extract using n-hexane, ethyl acetate, and n-butanol. The pharmaceutical composition for preventing cancer contains a compound of chemical formula 1, 2, 3, 4, or 5 as an active ingredient.

    Abstract translation: 目的：提供含有Youngia牙质提取物或从其分离的化合物的组合物以诱导醌还原酶（QR）的活化并改善肝功能。 构成：用于预防癌症的药物组合物含有作为活性成分的青ia牙提取物，其使用水，有机溶剂或其混合溶剂分离。 有机溶剂是C1-C4，乙酸乙酯，二氯甲烷或氯仿的醇。 青霉素小齿提取物通过增强醌还原酶活化来解毒致癌物质。 用于预防癌症的药物组合物含有作为活性成分的青霉素小齿状部分。 通过使用正己烷，乙酸乙酯和正丁醇频繁分选杨氏小齿提取物获得青霉素小齿级分。 用于预防癌症的药物组合物含有作为活性成分的化学式1,2,3,4或5的化合物。

    식품 및 식품 포장제 중의 비스페놀-에이 검출법
    35.
    发明公开
    식품 및 식품 포장제 중의 비스페놀-에이 검출법 失效
    二苯醚A食品或食品包装材料的检测方法

    公开(公告)号：KR1020020041713A

    公开(公告)日：2002-06-03

    申请号：KR1020000071402

    申请日：2000-11-28

    Applicant: 한국과학기술연구원

    Inventor： 명승운 ,  김명수 ,  김세진 ,  김기철

    IPC: G01N30/72

    Abstract: PURPOSE: Provided is a detection method of bisphenol-A among foods or foods packing material which shows selective and superior sensitivity for gas chromatography(GC) or GC/mass spectrometer so that it provides optimal analysis condition for the GC/mass spectrometer. CONSTITUTION: The detection method of bisphenol-A among the foods or the foods packing material comprises the steps of: (i) extracting bisphenol-A from the foods or the foods packing material in organic solvent and treating in sodium hydroxide; (ii) reacting with 100-1400μl of anhydrous acetic acid at 25-100deg.C for 5-20 minutes to produce derivatives of bisphenol-A; and (iii) analyzing concentration of bisphenol-A at the GC or the GC/mass spectrometer.

    Abstract translation: 目的：提供食品或食品包装材料中双酚A的检测方法，对气相色谱（GC）或GC /质谱仪具有选择性和优异的灵敏度，为GC /质谱仪提供最佳分析条件。 构成：食品或食品包装材料中双酚A的检测方法包括以下步骤：（i）从有机溶剂中的食品或食品包装材料中提取双酚A，并在氢氧化钠中处理; （ii）在25-100℃下与100-1400μl无水乙酸反应5-20分钟，得到双酚-A的衍生物; 和（iii）分析双酚A在GC或GC /质谱仪上的浓度。

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