Abstract:
본 발명은 손바닥선인장 추출물을 함유하는 약학 조성물에 관한 것으로, 더욱 상세하게는 손바닥선인장의 부탄올 추출물 또는 이 추출물의 산 가수분해물이 유효성분으로 함유되어 있음으로써 뇌신경 질환, 뇌혈관 질환 또는 심혈관 질환 보다 구체적으로는 뇌졸중, 뇌진탕, 알쯔하이머병, 파킨슨병, 뇌경색, 심근경색 등의 치료 및 예방에 유효한 약학 조성물에 관한 것이다. 손바닥선인장, 부탄올 추출물, 뇌졸중, 허혈, 신경세포 보호, 뇌신경질환
Abstract:
PURPOSE: A pharmaceutical composition containing Opuntia ficus-indica extract for preventing and treating memory loss is provided to strengthen ERK-CREB-BDNF signal in hippocampus. CONSTITUTION: A pharmaceutical composition for preventing and treating amnesia or memory loss-associated diseases contains Opuntia ficus-indica extract as an active ingredient. The extract is Opuntia ficus-indica stem extract. The extract is prepared using water, low alcohol of C1-C6, or mixture thereof. A health food for treating amnesia or memory loss contains the extract as an active ingredient. The health food is power, granules, tablet, capsule, or beverage.
Abstract:
PURPOSE: A composition containing Alnus hirsute stem extract or a compound isolated from the same is provided to protect hepatocytes and to prevent and treat liver diseases. CONSTITUTION: A composition for preventing and treating hepatotoxicity contains Alnus hirsute stem extract as an active ingredient. A composition for preventing and treating hepatotoxicity contains a compound of chemical formula 1 as an active ingredient. A method for preparing the Alnus hirsute extract comprises: a step of adding 0.1-10L of alcohol per 1kg of cut Alnus hirsute stem and refluxing at 60-100 °C for 2 to 6 hours; a step of filtering and decompressing extract; and a step of extracting with 1-5L of ethylacetate to obtain fraction.
Abstract:
본 발명은 활성산소 소거활성 및 항바이러스활성을 가지는 치자 추출물, 그로부터 분리된 신규한 화합물 및 그 용도에 관한 것이다. 보다 상세하게는 물 또는 유기용매로 추출되며, 유효성분으로 메틸 5- O -카페오일-4- O -시나포일퀴네이트, 메틸 3,5- O -디카페오일-4- O -(3-히드록시-3-메틸)글루타로일퀴네이트, 에틸 5- O -카페오일-4- O -시나포일퀴네이트, 메틸 3- O -카페오일-5- O -시나포일퀴네이트, 에틸 3- O -카페오일-5- O -시나포일퀴네이트, 3,5- O - 디카페오일퀴닉산 및 4,5- O -디카페오일퀴닉산을 포함하는 활성산소소거활성 및 항바이러스활성을 나타내는 치자추출물. 그로부터 분리된 신규 화합물에 관한 것이다. 본 발명에 의한 치자 추출물 및 분리된 신규화합물들은 DPPH 자유라디칼, 슈퍼옥사이드 음이온 라디칼 등의 활성산소 소거활성이 우수하여 활성 산소에 의한 질병을 치료 및 예방하는데 뛰어난 효과가 있으며, 인간면역결핍바이러스의 인티그라제에 대한 저해 활성 및 항바이러스활성도 높아 AIDS 등 바이러스성 질환의 치료에 응용될 수 있다. 치자, 활성산소 소거활성, 인티그라제(integrase), 항바이러스활성, AIDS,
Abstract:
본 발명은 손바닥선인장을 에틸 아세테이트로 추출하여 얻은 신경세포 보호효과를 갖는 추출물 및, 이 추출물 또는 이로부터 분리된 화합물을 유효성분으로 함유하는 신경세포 보호용 약학 조성물에 관한 것으로, 본 발명의 약학 조성물은 알쯔하이머병, 뇌졸중, 파킨슨병과 같은 뇌신경질환에 의한 뇌신경세포 손상, 허혈로 인한 세포와 조직 손상 또는 심근경색과 같은 심혈관계 질환의 예방 및 치료에 유용하게 사용될 수 있다.
Abstract:
PURPOSE: A new use of propolis and caffeic acid phenethyl(CAPE) ester as a component thereof is provided. Therefore, the propolis and CAPE can be used as a preventive and therapeutic agent for a disease generated from estrogen deficiency, or nitric oxide inhibitors, angiogenesis inhibitors. CONSTITUTION: An estrogen agonist contains propolis and caffeic acid phenethyl ester as an effective component, and an estrogen agonist composition is obtained by adding a pharmaceutically acceptable conventional excipient, carrier or adjuvant to the propolis and CAPE. The composition contains one formulation of: powder, a tablet, capsule, liquid and dispersing agent; a patch agent for mucosal absorption or transdermal absorption; and an injection.
Abstract:
PURPOSE: A composition for the prevention and treatment of ischemic disease containing aloesin as an effective ingredient and a preparation containing the same is provided. Because aloesin as an aloe component has an excellent neuroprotective effect and nerve-ethological recovering effect, the composition containing the same can be effectively used in treatment of nerve cell and tissue damage caused by cerebral ischemia. CONSTITUTION: The composition for prevention and treatment of ischemia disease contains aloesin of the formula 1 £8-C-β -D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one|, a pharmaceutically acceptable salt, hydrate or solvate or isomer and a pharmaceutically acceptable carrier thereof. The composition is formulated into a tablet, hard and soft gelatin capsule, liquid, suspension, injection, ointment, cream, gel or lotion. The composition is a neuroprotective composition for the prevention and treatment of ischemic apoplexy or concussion and a heart protecting composition for the prevention and treatment of ischemic myocardial infarction.
Abstract:
PURPOSE: A composition for the prevention and treatment of ischemic disease containing aloesin as an effective ingredient and a preparation containing the same is provided. Because aloesin as an aloe component has an excellent neuroprotective effect and nerve-ethological recovering effect, the composition containing the same can be effectively used in treatment of nerve cell and tissue damage caused by cerebral ischemia. CONSTITUTION: The composition for prevention and treatment of ischemia disease contains aloesin of the formula 1 £8-C-β -D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one|, a pharmaceutically acceptable salt, hydrate or solvate or isomer and a pharmaceutically acceptable carrier thereof. The composition is formulated into a tablet, hard and soft gelatin capsule, liquid, suspension, injection, ointment, cream, gel or lotion. The composition is a neuroprotective composition for the prevention and treatment of ischemic apoplexy or concussion and a heart protecting composition for the prevention and treatment of ischemic myocardial infarction.