公开(公告)号：CA2672727A1

公开(公告)日：2008-07-03

申请号：CA2672727

申请日：2007-12-21

Applicant: ABBOTT LAB

Inventor： GRONGSAARD PINTIPA ,  HAYES MARTIN E ,  ANSELL GRAHAM K ,  BREINLINGER ERIC C ,  WALLACE GRIER A ,  FIX-STENZEL SHANNON R ,  GORDON THOMAS D ,  HOBSON ADRIAN D ,  CUSACK KEVIN P

IPC: C07C229/48 ,  A61K31/13 ,  A61K31/19 ,  A61K31/197 ,  A61K31/343 ,  A61K31/397 ,  A61K31/40 ,  A61K31/4192 ,  A61K31/661 ,  A61P25/00 ,  A61P25/28 ,  C07C49/753 ,  C07C59/54 ,  C07C215/00 ,  C07C217/00 ,  C07C217/74 ,  C07C229/14 ,  C07C255/46 ,  C07D205/04 ,  C07D207/08 ,  C07D249/06 ,  C07D263/52 ,  C07D307/79 ,  C07F9/09

Abstract: The present invention is directed to novel, potent, and selective agents, which are agonists or antagonists of the one or more of the individual rece ptors of the S1P receptor family. The compounds of the invention are useful as therapeutics for treating medical conditions associated with agonism or a ntagonism of the individual receptors of the S1P receptor family.