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公开(公告)号：WO2007084728A2
公开(公告)日：2007-07-26
申请号：PCT/US2007001548
申请日：2007-01-19
Applicant: ABBOTT LAB , ROTH GREGORY P , WALLACE GRIER A , GEORGE DAWN M , GRONGSAARD PINTIPA , HAYES MARTIN , BREINLINGER ERIC C
Inventor： ROTH GREGORY P , WALLACE GRIER A , GEORGE DAWN M , GRONGSAARD PINTIPA , HAYES MARTIN , BREINLINGER ERIC C
IPC: A61K31/4184
CPC classification number: C07D401/06 , C07D401/12 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/06 , C07D417/06 , C07D417/12 , C07D471/04 , C07D487/04
Abstract: Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I), wherein the substituents are as defined herein, which are useful as therapeutic agents.
Abstract translation: 式（I）的新型化合物或其药学上可接受的盐，前药和其生物活性代谢物，其中取代基如本文所定义，其可用作治疗剂。
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2.发明公开SPHINGOSINE-1 -PHOSPHATE RECEPTOR AGONIST AND ANTAGONIST COMPOUNDS 审中-公开SPHINGOSINE 1磷酸受体激动剂和拮抗剂化合物
公开(公告)号：EP2120575A4
公开(公告)日：2011-04-27
申请号：EP07863237
申请日：2007-12-21
Applicant: ABBOTT LAB
Inventor： WALLACE GRIER A , BREINLINGER ERIC C , CUSACK KEVIN P , FIX-STENZEL SHANNON R , GORDON THOMAS D , HOBSON ADRIAN D , HAYES MARTIN E , ANSELL GRAHAM K , GRONGSAARD PINTIPA
IPC: A01N43/50 , A61K31/415 , A61P25/28 , C07C215/38 , C07C215/42 , C07C217/74 , C07C229/14 , C07C229/48 , C07D205/04 , C07D207/12 , C07D207/14 , C07D213/30 , C07D263/32 , C07D263/52 , C07D271/06 , C07D307/22 , C07D307/24 , C07D333/16 , C07D413/04 , C07F9/30 , C07F9/38 , C07F9/40 , C07F9/653 , C07F9/655 , C07F9/6553
CPC classification number: C07D413/04 , C07C215/38 , C07C215/42 , C07C217/52 , C07C217/74 , C07C229/14 , C07C229/48 , C07C2601/02 , C07C2601/08 , C07D205/04 , C07D207/12 , C07D207/14 , C07D213/30 , C07D263/32 , C07D263/52 , C07D271/06 , C07D307/22 , C07D307/24 , C07D333/16 , C07D491/107 , C07F9/091 , C07F9/301 , C07F9/3808 , C07F9/3826 , C07F9/4006 , C07F9/653 , C07F9/65515 , C07F9/655345
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公开(公告)号：EP1983992A4
公开(公告)日：2010-08-18
申请号：EP07717989
申请日：2007-01-19
Applicant: ABBOTT LAB
Inventor： ROTH GREGORY P , WALLACE GRIER A , GEORGE DAWN M , GRONGSAARD PINTIPA , HAYES MARTIN , BREINLINGER ERIC C
IPC: A61K31/496
CPC classification number: C07D401/06 , C07D401/12 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/06 , C07D417/06 , C07D417/12 , C07D471/04 , C07D487/04
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公开(公告)号：EP2109364A4
公开(公告)日：2010-04-14
申请号：EP07867755
申请日：2007-12-14
Applicant: ABBOTT LAB
Inventor： HOBSON ADRIAN D , FIX-STENZEL SHANNON , CUSACK KEVIN P , BREINLINGER ERIC C , ANSELL GRAHAM K , STOFFEL ROBERT H , WOLLER KEVIN R , GRONGSAARD PINTIPA
CPC classification number: C07D271/07 , C07D271/06 , C07D413/04 , C07D413/06 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/04 , C07D471/04 , C07D487/04
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公开(公告)号：NO20092376L
公开(公告)日：2009-06-22
申请号：NO20092376
申请日：2009-06-22
Applicant: ABBOTT LAB
Inventor： GORDON THOMAS D , CUSACK KEVIN P , WALLACE GRIER A , BREINLINGER ERIC C , FIX-STENZEL SHANNON R , HOBSON ADRIAN D , HAYES MARTIN E , ANSELL GRAHAM K , GRONGSAARD PINTIPA
IPC: C07D413/04 , C07D215/38 , C07D215/42
Abstract: The present invention is directed to novel, potent, and selective agents, which are agonists or antagonists of the one or more of the individual receptors of the S1P receptor family. The compounds of the invention are useful as therapeutics for treating medical conditions associated with agonism or antagonism of the individual receptors of the S1P receptor family.
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Patent Agency Ranking
公开(公告)号：MX2009006751A
公开(公告)日：2009-06-30
申请号：MX2009006751
申请日：2007-12-21
Applicant: ABBOTT LAB
Inventor： FIX-STENZEL SHANNON R , GORDON THOMAS D , WALLACE GRIER A , GRONGSAARD PINTIPA , CUSACK KEVIN P , HOBSON ADRIAN D , BREINLINGER ERIC C , ANSELL GRAHAM K , HAYES MARTIN E
IPC: A01N43/50 , A61K31/415
Abstract: La presente invención se dirige a agentes novedosos, potentes y selectivos, los cuales son agonistas o antagonistas del uno omás de los receptores individuales de la familia del receptor S1P. Los compuestos de la presente invención son útiles como terapéuticos para tratar condiciones médicas asociadas con agonismo o antagonismo de los receptores individuales de la familia del receptor S1P.
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公开(公告)号：CA2672727A1
公开(公告)日：2008-07-03
申请号：CA2672727
申请日：2007-12-21
Applicant: ABBOTT LAB
Inventor： GRONGSAARD PINTIPA , HAYES MARTIN E , ANSELL GRAHAM K , BREINLINGER ERIC C , WALLACE GRIER A , FIX-STENZEL SHANNON R , GORDON THOMAS D , HOBSON ADRIAN D , CUSACK KEVIN P
IPC: C07C229/48 , A61K31/13 , A61K31/19 , A61K31/197 , A61K31/343 , A61K31/397 , A61K31/40 , A61K31/4192 , A61K31/661 , A61P25/00 , A61P25/28 , C07C49/753 , C07C59/54 , C07C215/00 , C07C217/00 , C07C217/74 , C07C229/14 , C07C255/46 , C07D205/04 , C07D207/08 , C07D249/06 , C07D263/52 , C07D307/79 , C07F9/09
Abstract: The present invention is directed to novel, potent, and selective agents, which are agonists or antagonists of the one or more of the individual rece ptors of the S1P receptor family. The compounds of the invention are useful as therapeutics for treating medical conditions associated with agonism or a ntagonism of the individual receptors of the S1P receptor family.
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公开(公告)号：CA2637674A1
公开(公告)日：2007-07-26
申请号：CA2637674
申请日：2007-01-19
Applicant: ABBOTT LAB
Inventor： ROTH GREGORY P , BREINLINGER ERIC C , HAYES MARTIN , GEORGE DAWN M , WALLACE GRIER A , GRONGSAARD PINTIPA
IPC: A61K31/496
Abstract: Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I) wherein the substituents are as defined herein, which are useful as therapeutic agents.
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公开(公告)号：ZA200903873B
公开(公告)日：2010-10-27
申请号：ZA200903873
申请日：2009-06-03
Applicant: ABBOTT LAB
Inventor： WALLACE GRIER A , BREINLINGER ERIC C , CUSACK KEVIN P , FIX-STENZEL SHANNON R , GORDON THOMAS D , HOBSON ADRIAN D , HAYES MARTIN E , ANSELL GRAHAM K , GRONGSAARD PINTIPA
IPC: A01N20060101 , A61K20060101
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公开(公告)号：ECSP099435A
公开(公告)日：2009-07-31
申请号：ECSP099435
申请日：2009-06-15
Applicant: ABBOTT LAB
Inventor： WALLACE GRIER A , FIX-STENZEL SHANNON R , HAYES MARTIN E , BREINLINGER ERIC C , GORDON THOMAS D , ANSELL GRAHAM K , CUSAK KEVIN P , HOBSON ADRIAN D , GRONGSAARD PINTIPA
IPC: A01N43/50 , A61K31/415
Abstract: La presente invención esta dirigida a agentes nuevos, potentes y selectivos, los cuales son agonistas o antagonistas de uno o más de los receptores individuales de la familia de receptores S1P. Los compuestos de la invención son usados como terapia en el tratamiento de condiciones médicas asociadas con el agonismo o antagonismo de los receptores individuales de la familia de receptores S1P.
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