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公开(公告)号：PL343264A1
公开(公告)日：2001-07-30
申请号：PL34326499
申请日：1999-03-05
Applicant: ABBOTT LAB
Inventor： NIENABER VICKI L , GREER JONATHAN , ABAD-ZAPATERO CELERINO , NORBECK DANIEL W
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公开(公告)号：CZ20003246A3
公开(公告)日：2001-03-14
申请号：CZ20003246
申请日：1999-03-05
Applicant: ABBOTT LAB
Inventor： NIENABER VICKI L , GREER JONATHAN , ABAD-ZAPATERO CELERINO , NORBECK DANIEL W
IPC: G01N33/00
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公开(公告)号：BR9908563A
公开(公告)日：2000-11-21
申请号：BR9908563
申请日：1999-03-05
Applicant: ABBOTT LAB
Inventor： NIENABER VICKI L , GREER JONATHAN , ABAD-ZAPATERO CELERINO , NORBECK DANIEL W
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公开(公告)号：AU2887099A
公开(公告)日：1999-09-20
申请号：AU2887099
申请日：1999-03-01
Applicant: ABBOTT LAB
Inventor： NIENABER VICKI L , GREER JONATHAN , ABAD-ZAPATERO CELERINO , NORBECK DANIEL W
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公开(公告)号：PL286388A1
公开(公告)日：1991-05-06
申请号：PL28638890
申请日：1990-08-07
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN
Abstract: The present invention relates to novel "pseudo" nonapeptide and decapeptide derivatives of LHRH. More particularly the present invention relates to derivatives of LHRH wherein the nitrogen atom of at least one of the amide bonds has been alkylated.
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Patent Agency Ranking
公开(公告)号：HUT54387A
公开(公告)日：1991-02-28
申请号：HU491090
申请日：1990-08-06
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN
Abstract: The present invention relates to novel "pseudo" nonapeptide and decapeptide derivatives of LHRH. More particularly the present invention relates to derivatives of LHRH wherein the nitrogen atom of at least one of the amide bonds has been alkylated.
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公开(公告)号：CA2022437A1
公开(公告)日：1991-02-08
申请号：CA2022437
申请日：1990-08-01
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
Abstract: The present invention relates to novel LHRH analogs. The LHRH analogs include "pseudo" hexapeptide, heptapeptide, octapeptide and nonapeptide analogs of LHRH, wherein all or some of the amino acids 1, 2 and 3 have been eliminated and the remaining (2-9), (2-10), (3-9), (3-10), (4-9) or (4-10) peptide is linked to various carboxylic acids which take the place of amino acids 1, 2 or 3 in LHRH.
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公开(公告)号：NO903454D0
公开(公告)日：1990-08-06
申请号：NO903454
申请日：1990-08-06
Applicant: ABBOTT LAB
Inventor： HAVIV FORTUNA , GREER JONATHAN , PALABRICA CHRISTOPHER A , FITZPATRICK TIMOTHY D
Abstract: The present invention relates to novel LHRH analogs. The LHRH analogs include "pseudo" hexapeptide, heptapeptide, octapeptide and nonapeptide analogs of LHRH, wherein all or some of the amino acids 1, 2 and 3 have been eliminated and the remaining (2-9), (2-10), (3-9), (3-10), (4-9) or (4-10) peptide is linked to various carboxylic acids which take the place of amino acids 1, 2 or 3 in LHRH.
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公开(公告)号：DE69937292T2
公开(公告)日：2008-07-03
申请号：DE69937292
申请日：1999-03-05
Applicant: ABBOTT LAB
Inventor： NIENABER VICKI L , GREER JONATHAN , ABAD-ZAPATERO CELERINO , NORBECK DANIEL W
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公开(公告)号：HU0102011A2
公开(公告)日：2001-11-28
申请号：HU0102011
申请日：1999-03-11
Applicant: ABBOTT LAB
Inventor： BRUNCKO MILAN , CRAWFORD BRADLEY W , DALTON CHRISTOPHER R , FREY LISA MARIE , GREER JONATHAN , HAVIV FORTUNA , KAMINSKI MICHELE A , MORT NICHOLAS A , RANDOLPH JOHN , SAUER DARYL R
IPC: A61K31/7042 , A61K31/7048 , A61K31/7056 , A61P5/24 , A61P13/08 , A61P15/00 , A61P35/00 , A61P43/00 , C07H17/08 , C07H1/00
Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
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