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公开(公告)号：SI2039685T1
公开(公告)日：2013-04-30
申请号：SI200432001
申请日：2004-02-25
Applicant: ARRAY BIOPHARMA INC
Inventor： MUNSON MARK , MARESKA DAVID A , KIM YOUNGBOO , GRONEBERG ROBERT , RIZZI JAMES , RODRIGUEZ MARTHA , KIM GANGHYEOK , VIGERS GUY , RAO CHANG , BALACHARI DEVAN , HARVEY DARREN
IPC: C07D401/00 , A61K20060101 , A61K31/00 , A61K31/4745 , A61K31/503 , A61K31/675 , C07D20060101 , C07D231/00 , C07D231/56 , C07D261/00 , C07D261/20 , C07D401/14 , C07D403/00 , C07D403/04 , C07D403/12 , C07D405/00 , C07D405/12 , C07D413/00 , C07D413/12 , C07D471/00 , C07D471/02 , C07D471/04 , C07D487/02 , C07D491/02 , C07D498/02
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公开(公告)号：CA2821712A1
公开(公告)日：2012-06-21
申请号：CA2821712
申请日：2011-12-13
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , DELISLE ROBERT KIRK , HICKEN ERIK JAMES , KENNEDY APRIL L , MARESKA DAVID A , MARMSATER FREDRIK P , MUNSON MARK C , NEWHOUSE BRAD , RAST BRYSON , RIZZI JAMES P , RODRIGUEZ MARTHA E , TOPALOV GEORGE T , ZHAO QIAN
IPC: C07D471/04 , A61K31/437 , A61P35/00
Abstract: Compounds of Formula I: and pharmaceutically acceptable salts thereof in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of fibrosis, bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases, pain and burns in a mammal.
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公开(公告)号：IS2675B
公开(公告)日：2010-09-15
申请号：IS8037
申请日：2005-09-21
Applicant: ARRAY BIOPHARMA INC
Inventor： MUNSON MARK , MARESKA DAVID A , KIM YOUNGBOO , GRONEBERG ROBERT , RIZZI JAMES , RODRIGUEZ MARTHA , KIM GANGHYEOK , VIGERS GUY , RAO CHANG , BALACHARI DEVAN , HARVEY DARREN
IPC: C07D401/14 , A61K20060101 , A61K31/416 , A61K31/4162 , A61K31/4745 , A61K31/503 , A61K31/675 , A61P35/00 , C07D20060101 , C07D231/56 , C07D261/20 , C07D403/04 , C07D413/12 , C07D471/02 , C07D471/04 , C07D487/02 , C07D491/02
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公开(公告)号：IS8810A
公开(公告)日：2009-03-16
申请号：IS8810
申请日：2009-03-16
Applicant: ARRAY BIOPHARMA INC
Inventor： MUNSON MARK , MARESKA DAVID A , KIM YOUNGBOO , GROENBERG ROBERT , RIZZI JAMES , RODRIGUEZ MARTHA , KIM GANGHYEOK , VIGERS GUY P A , RAO CHANG , BALACHARI DEVAN , HARVEY DARREN
IPC: A61K20060101 , A61K31/4745 , A61K31/503 , A61K31/675 , C07D20060101 , C07D231/56 , C07D261/20 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/02 , C07D471/04 , C07D487/02 , C07D491/02 , C07D498/02
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公开(公告)号：ZA200507874B
公开(公告)日：2007-03-28
申请号：ZA200507874
申请日：2004-02-25
Applicant: ARRAY BIOPHARMA INC
Inventor： MARK MUNSON , MARESKA DAVID A , YOUNGBOO KIM , ROBERT GRONEBERG , JAMES RIZZI , MARTHA RODRIGUEZ , GANGHYEOK KIM , GUY VIGERS , CHANG RAO , DEVAN BALACHARI , DARREN HARVEY
IPC: A61K20090101 , A61K31/4745 , A61K31/503 , A61K31/675 , C07D20060101 , C07D231/56 , C07D261/20 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/02 , C07D471/04 , C07D487/02 , C07D491/02 , C07D498/02
Abstract: Compounds having the Formula: wherein Y, A, W, B, U, V, X and Ar 1 have the meanings given in the specification, which compounds are useful in therapy as p38-inhibitors.
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Patent Agency Ranking
公开(公告)号：NO20085373L
公开(公告)日：2005-11-29
申请号：NO20085373
申请日：2008-12-23
Applicant: ARRAY BIOPHARMA INC
Inventor： MUNSON MARK , KIM YOUNGBOO , RIZZI JAMES , KIM GANGHYEOK , VIGERS GUY , RAO CHANG , BALACHARI DEVAN , HARVEY DARREN , MARESKA DAVID A , GRONEBERG ROBERT , RODRIGUEZ MARTHA
IPC: C07D471/04 , A61K20060101 , A61K31/416 , A61K31/4745 , A61K31/503 , A61K31/675 , A61P29/00 , C07D20060101 , C07D231/56 , C07D261/20 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/02 , C07D487/02 , C07D491/02 , C07D498/02
Abstract: Compounds having the Formula: wherein Y, A, W, B, U, V, X and Ar 1 have the meanings given in the specification, which compounds are useful in therapy as p38-inhibitors.
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公开(公告)号：PA8596901A1
公开(公告)日：2004-11-26
申请号：PA8596901
申请日：2004-03-02
Applicant: ARRAY BIOPHARMA INC
Inventor： GRONEBERG ROBERT D , MARESKA DAVID A , YOUNGBOO KIM , MUNSON MARK , RIZZI JAMES , KIM GANGHYEOK , VIGERS GUY , CHANG RAO , BALACHARI DEVAN , DARREN HARVEY
IPC: A61K20060101 , A61K31/4745 , A61K31/503 , A61K31/675 , C07D20060101 , C07D231/56 , C07D261/20 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/02 , C07D471/04 , C07D487/02 , C07D491/02 , C07D498/02
Abstract: LA PRESENTE INVENCION SE RELACIONA CON INHIBIDORES DE P38, Y METODOS PARA PRODUCIR ESTOS INHIBIDORES. LA PRESENTE INVENCION ADEMAS PROPORCIONAR COMPOSICIONES FARMACEUTICAS QUE COMPRENDE LOS INHIBIDORES DE LA INVENCION Y METODOS PARA UTILIZAR LOS INHIBIDORES Y COMPOSICIONES FARMACEUTICAS EN EL TRATAMIENTO Y PREVENCION DE VARIOS DESORDENES MEDIADOS POR P38.
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公开(公告)号：AU2018201903B2
公开(公告)日：2019-09-19
申请号：AU2018201903
申请日：2018-03-16
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , DELISLE ROBERT KIRK , HICKEN ERIK JAMES , KENNEDY APRIL L , MARESKA DAVID A , MARMSATER FREDRIK P , MUNSON MARK C , NEWHOUSE BRAD , RAST BRYSON , RIZZI JAMES P , RODRIGUEZ MARTHA E , TOPALOV GEORGE T , ZHAO QIAN
IPC: C07D471/04 , A61K31/437 , A61P35/00
Abstract: [007801 Compounds of Formula I: and pharmaceutically acceptable salts thereof in which R, R2, R3, R4, R5 and R6 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of fibrosis, bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases, pain and burns in a mammal.
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公开(公告)号：CA2821712C
公开(公告)日：2019-02-12
申请号：CA2821712
申请日：2011-12-13
Applicant: ARRAY BIOPHARMA INC
Inventor： BOYS MARK LAURENCE , DELISLE ROBERT KIRK , HICKEN ERIK JAMES , KENNEDY APRIL L , MARESKA DAVID A , MARMSATER FREDRIK P , MUNSON MARK C , NEWHOUSE BRAD , RAST BRYSON , RIZZI JAMES P , RODRIGUEZ MARTHA E , TOPALOV GEORGE T , ZHAO QIAN
IPC: C07D471/04 , A61K31/437 , A61P35/00
Abstract: Compounds of Formula I: and pharmaceutically acceptable salts thereof are inhibitors of cFMS and are useful in the treatment of fibrosis, bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases, pain and burns in a mammal (see formula I)
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公开(公告)号：PT2651939E
公开(公告)日：2015-08-04
申请号：PT11808427
申请日：2011-12-13
Applicant: ARRAY BIOPHARMA INC
Inventor： MARMSATER FREDRIK P , TOPALOV GEORGE T , DELISLE ROBERT KIRK , HICKEN ERIK JAMES , KENNEDY APRIL L , MUNSON MARK C , RIZZI JAMES P , RODRIGUEZ MARTHA E , ZHAO QIAN , LAURENCE BOYS MARK , MARESKA DAVID A , NEWHOUSE BRAD , RAST BRYSON
IPC: C07D471/04 , A61K31/437 , A61P35/00
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