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    Preparation of water soluble or dispersible copolymer, useful as solubilizer for the preparation of the aqueous active or effective composition, comprises polymerizing a polymer with an anhydride reactive group and an amide compound
    36.
    发明专利
    Preparation of water soluble or dispersible copolymer, useful as solubilizer for the preparation of the aqueous active or effective composition, comprises polymerizing a polymer with an anhydride reactive group and an amide compound 未知

    公开(公告)号：DE102005026711A1

    公开(公告)日：2007-02-01

    申请号：DE102005026711

    申请日：2005-06-09

    Applicant: BASF AG

    Inventor： DIETSCHE FRANK ,  BOUILLO NATHALIE ,  HUEFFER STEPHAN ,  LANGE RONALD FRANS MARIA ,  PINNEKER OLGA ,  DROHMANN CHRISTIAN

    IPC: C08F299/00 ,  A61K8/06 ,  A61K8/81 ,  C08F2/00 ,  C08F210/10 ,  C08F226/00 ,  C09K23/52

    Abstract: Preparation of water soluble or water dispersible copolymer comprises either polymerizing at least a polymer (P1) having at least an anhydride reactive group, and at least a compound containing alpha , beta -ethylenically unsaturated amide group, or reacting at least a hydrolysis product of P1 with a polyolefin (P2) containing at least a anhydride group, where the reaction step takes place using a shear force. Preparation of water soluble or water dispersible copolymer comprises either polymerizing at least a polymer (P1) having at least an anhydride reactive group, and at least a compound (M1) containing alpha , beta -ethylenically unsaturated amide group of formula (R1>-C(=O)-NR2>R3>), or reacting at least a hydrolysis product of P1 with a polyolefin (P2) containing at least a anhydride group, where the reaction step takes place using a shear force. R2>CH2=CR4>; R4>H or 1-4C-alkyl; and either R1>, R3>H, (cyclo)alkyl, heterocycloalkyl or (hetero)aryl; or R1>R3>NH2lactam with 5 to 8 ring atoms. Independent claims are included for: (1) the copolymer obtained by the above process; (2) an active or effective composition comprising the copolymer and at least an active or effective material with an solubility of 10 g/l in water at 25[deg]C and 1013 mbar; (3) a method for the preparation of the aqueous active or effective composition comprising either preparing homogeneous, non-aqueous mixture containing the copolymer and the active or effective material and dispersing the obtained mixture in water, or preparing a solution of the active or effective material and the copolymer in an organic solvent having boiling point less than water, mixing the obtained mixture and removing the organic agent, or preparing the active or effective material in an aqueous solution copolymer at a temperature above the melt temperature of the active agent; and (4) a cosmetic, pharmaceutical or plant protective agent comprising the copolymer, at least the cosmetic active or effective material and optionally at least an auxiliary material.

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