公开(公告)号：BR9813430A

公开(公告)日：2000-10-17

申请号：BR9813430

申请日：1998-11-26

Applicant: BASF AG

Inventor： BAUER PETER ,  LANGE ARMIN ,  KARER RAINER ,  ROSENDORFER PHILIPP ,  HECKER MANFRED ,  SCHWEIER GUENTHER ,  MICKLITZ WOLFGANG ,  EVERTZ KASPAR ,  FEINDT HANS-JACOB

IPC: C08J5/18 ,  C08F2/34 ,  C08F4/02 ,  C08F4/24 ,  C08F4/69 ,  C08F10/02 ,  C08F210/02

Abstract: A continuous vapor-phase fluidized-bed process for the preparation of ethylene homopolymers and copolymers having a density of from 0.87 to 0.97 g/cm in which ethylene or mixtures of ethylene and C3-C8 a-monoolefins are (co)polymerized in the presence of a supported chromium catalyst in the polymerization zone of a vapor-phase fluidized-bed reactor under pressures ranging from 1 to 100 bar and at temperatures ranging from 30° to 125° C. in the vapor phase in an agitated bed of bulk material comprising particulate polymer, the resultant heat of polymerization is removed by cooling the recirculated reactor gas and the resulting (co)polymer is removed from the vapor-phase fluidized-bed reactor, wherein, for the preparation of a (co)polymer of a specific density d, the (co)polymerization is carried out at a temperature which is in a range restricted by an upper envelope defined by equation Iand a lower envelope defined by equation IIin which the variables have the following meanings:TH is the highest reaction temperature in ° C.;TL is the lowest reaction temperature in ° C.;d' is the numerical value of the density d of the (co)polymer to be synthesized.

公开(公告)号：DE19855440A1

公开(公告)日：2000-06-08

申请号：DE19855440

申请日：1998-12-01

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  KOTHRADE STEPHAN ,  KESLER THOMAS ,  LANGE ARMIN ,  HOFMANN JUERGEN ,  REINHOLD ULRICH

IPC: A61J3/10 ,  A61K9/16 ,  A61K9/20 ,  B29C47/42

Abstract: The invention relates to a method for producing solid forms of administration by means of melt extrusion. A polymer binder, at least one pharmaceutical active agent and optionally, other additives are mixed and the mixture is melted in an extruder and then extruded in the form of a continuous plastic product strand. The inventive method is characterised in that the extruder used is a planetary roller extruder (10) which preferably has one central spindle (13) and six planetary spindles (14).

公开(公告)号：CA2352874A1

公开(公告)日：2000-06-08

申请号：CA2352874

申请日：1999-11-30

Applicant: BASF AG

Inventor： REINHOLD ULRICH ,  HOFMANN JURGEN ,  KESSLER THOMAS ,  KOTHRADE STEPHAN ,  LANGE ARMIN ,  BERNDL GUNTHER

IPC: A61J3/10 ,  A61K9/16 ,  A61K9/20 ,  B29C47/42

Abstract: The invention relates to a method for producing solid forms of administratio n by means of melt extrusion. A polymer binder, at least one pharmaceutical active agent and optionally, other additives are mixed and the mixture is melted in an extruder and then extruded in the form of a continuous plastic product strand. The inventive method is characterised in that the extruder used is a planetary roller extruder (10) which preferably has one central spindle (13) and six planetary spindles (14).

公开(公告)号：NO995056A

公开(公告)日：1999-10-15

申请号：NO995056

申请日：1999-10-15

Applicant: BASF AG

Inventor： MIHAN SHAHRAM ,  LANGE ARMIN ,  ROSENDORFER PHILIPP ,  HACK JOHANNES

IPC: C08F2/34 ,  C08F2/44 ,  C08F4/60 ,  C08F4/69 ,  C08F10/00 ,  C08F10/02

CPC classification number: C08F10/02 ,  C08F2/005 ,  C08F4/24 ,  C08F2/44

公开(公告)号：AU1004199A

公开(公告)日：1999-07-22

申请号：AU1004199

申请日：1999-01-04

Applicant: BASF AG

Inventor： LANGE ARMIN ,  MICKLITZ WOLFGANG ,  KARER RAINER ,  EVERTZ KASPAR ,  MIHAN SHAHRAM ,  FEINDT HANS-JACOB ,  HECKER MANFRED ,  BAUER PETER ,  ROSENDORFER PHILIPP

IPC: C08K13/02 ,  C08F2/00 ,  C08F2/34 ,  C08F6/02 ,  C08F10/00 ,  C08F10/02 ,  C08F10/06 ,  C08F210/16

Abstract: Continuous gas phase polymerization for producing ethylene homopolymers and -copolymers, comprises polymerizing ethylene or monoolefin from but-1-en, pent-1-en, 2-methylpentene, hex-1-en, hept-1-en and oct-1-en in the a polymerization reactor; and endowing a catalyst poison with boiling point higher than a circle gas pipeline, and molecular weight greater than 100 g/mol at a position after the reactor, but before the cooler and compressor. Continuous gas phase polymerization for producing ethylene homopolymers and -copolymers, comprises polymerizing ethylene and/or monoolefin from but-1-en, pent-1-en, 2-methylpentene, hex-1-en, hept-1-en or oct-1-en, in the polymerization zone of a gas phase polymerization reactor at 30-125[deg]C and 1-100 bar in the gaseous phase in a finely divided polymer bed, in the presence of a metallocene catalyst in carrier form polymer, where a reactor gas is lead into the circle gas pipeline for the removal of the polymerization heat; and endowing a catalyst poison with boiling point higher than circle gas pipeline and molecular weight greater than 100 g/mol at a position after the reactor but before the cooler and compressor, for preventing polymer linings, such that the productivity of the catalyst is not essentially affected in the reactor.