公开(公告)号：SK59896A3

公开(公告)日：1997-07-09

申请号：SK59896

申请日：1994-11-10

Applicant: BASF AG

Inventor： KROGER BURKHARD ,  SEULBERGER HARALD ,  MEYER THOMAS ,  SCHMIDT MARTIN ,  JACOB ELARD ,  OTTER RAINER ,  SUBKOWSKI THOMAS ,  HILLEN HEINZ

IPC: G01N33/573 ,  A01K67/027 ,  A61K31/70 ,  A61K35/12 ,  A61K38/00 ,  A61K38/43 ,  A61K38/48 ,  A61K39/395 ,  A61K48/00 ,  A61P9/00 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  A61P11/00 ,  A61P13/02 ,  A61P15/00 ,  A61P25/04 ,  A61P25/28 ,  A61P29/00 ,  A61P31/04 ,  C07H21/04 ,  C07K14/47 ,  C07K16/40 ,  C12N5/00 ,  C12N5/10 ,  C12N9/64 ,  C12N15/09 ,  C12N15/113 ,  C12N15/57 ,  C12R1/91 ,  C12N15/11

Abstract: PCT No. PCT/EP94/03706 Sec. 371 Date May 16, 1996 Sec. 102(e) Date May 16, 1996 PCT Filed Nov. 10, 1994 PCT Pub. No. WO95/14095 PCT Pub. Date May 26, 1995The invention relates to endothelin-converting enzymes containing the polypeptide sequence described in SEQ. ID. NO. 30 or SEQ. ID. NO. 36 or functional fragments thereof, genes which code for such enzymes, and processes for producing the said enzymes and the use thereof.

公开(公告)号：NO962023L

公开(公告)日：1996-07-16

申请号：NO962023

申请日：1996-05-15

Applicant: BASF AG

Inventor： KROGER BURKHARD ,  SEULBERGER HARALD ,  MEYER THOMAS ,  SCHMIDT MARTIN ,  JACOB ELARD ,  OTTER RAINER ,  SUBKOWSKI THOMAS ,  HILLEN HEINZ

IPC: G01N33/573 ,  A01K67/027 ,  A61K31/70 ,  A61K35/12 ,  A61K38/00 ,  A61K38/43 ,  A61K38/48 ,  A61K39/395 ,  A61K48/00 ,  A61P9/00 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  A61P11/00 ,  A61P13/02 ,  A61P15/00 ,  A61P25/04 ,  A61P25/28 ,  A61P29/00 ,  A61P31/04 ,  C07H21/04 ,  C07K14/47 ,  C07K16/40 ,  C12N5/00 ,  C12N5/10 ,  C12N9/64 ,  C12N15/09 ,  C12N15/113 ,  C12N15/57 ,  C12R1/91

Abstract: PCT No. PCT/EP94/03706 Sec. 371 Date May 16, 1996 Sec. 102(e) Date May 16, 1996 PCT Filed Nov. 10, 1994 PCT Pub. No. WO95/14095 PCT Pub. Date May 26, 1995The invention relates to endothelin-converting enzymes containing the polypeptide sequence described in SEQ. ID. NO. 30 or SEQ. ID. NO. 36 or functional fragments thereof, genes which code for such enzymes, and processes for producing the said enzymes and the use thereof.

公开(公告)号：NZ242758A

公开(公告)日：1994-12-22

申请号：NZ24275892

申请日：1992-05-15

Applicant: BASF AG

Inventor： GRAMMENOS WASSILIOS ,  KIRSTGEN REINHARD ,  OBERDORF KLAUS ,  SAUTER HUBERT ,  ROEHL FRANZ ,  OTTER RAINER ,  AMMERMANN EBERHARD ,  LORENZ GISELA ,  KARDORFF UWE ,  KUENAST CHRISTOPH

IPC: A01N35/10 ,  A01N43/54 ,  A01N43/56 ,  A01N43/78 ,  C07C59/64 ,  C07C69/145 ,  C07C69/618 ,  C07C69/65 ,  C07C69/73 ,  C07C69/732 ,  C07C69/734 ,  C07C69/738 ,  C07C69/76 ,  C07C69/767 ,  C07C69/92 ,  C07C69/94 ,  C07C251/48 ,  C07C251/52 ,  C07C251/54 ,  C07C323/62 ,  C07D207/337 ,  C07D209/18 ,  C07D209/30 ,  C07D213/64 ,  C07D231/12 ,  C07D231/18 ,  C07D235/26 ,  C07D235/28 ,  C07D239/26 ,  C07D239/34 ,  C07D239/38 ,  C07D239/46 ,  C07D239/52 ,  C07D239/56 ,  C07D239/60 ,  C07D239/88 ,  C07D239/90 ,  C07D261/08 ,  C07D261/10 ,  C07D261/12 ,  C07D261/20 ,  C07D263/16 ,  C07D263/38 ,  C07D263/40 ,  C07D263/46 ,  C07D263/56 ,  C07D263/58 ,  C07D271/10 ,  C07D271/113 ,  C07D275/02 ,  C07D277/20 ,  C07D277/30 ,  C07D277/32 ,  C07D277/34 ,  C07D277/36 ,  C07D277/64 ,  C07D277/74 ,  C07D285/08 ,  C07D285/12 ,  C07D285/125 ,  C07D307/54 ,  C07D317/30 ,  C07D333/24 ,  C07F9/40 ,  C07C59/60 ,  C07C219/14 ,  C07C235/42 ,  C07C255/41 ,  C07C321/20 ,  C07D241/52 ,  C07D241/42 ,  C07D241/40 ,  C07D317/12 ,  C07D317/14 ,  C07F9/11 ,  A01N37/06 ,  A01N37/16 ,  A01N37/34 ,  A01N37/36 ,  A01N37/40 ,  A01N37/44 ,  A01N43/26 ,  A01N43/28 ,  A01N43/30 ,  A01N43/40 ,  A01N43/52 ,  A01N43/60 ,  A01N43/80 ,  A01N43/82 ,  A01N57/10

Abstract: alpha -Phenylacrylic acid derivatives I in which n = 0 to 4; y = 0 or 1; R = H; alkyl; alkenyl; alkynyl; optionally substituted cycloalkyl; vinyl or ethynyl if W represents a direct bond; R = CN; alkenyl; alkynyl; optionally substituted cycloalkyl; optionally substituted alkyl; R = H; NO2; CN; halogen; alkyl; alkoxy; haloalkyl; haloalkoxy; alkylthio; or, in the event that n represents 2, 3 or 4, two adjacent substituents R together are optionally substituted 1,3-butadiene-1,4-diyl; R = H; CHO; optionally substituted alkyl; optionally substituted alkenyl; optionally substituted alkynyl; an optionally substituted saturated or unsaturated cyclic radical; (phenyl)3P-; (phenyl)2PO-; (alkoxy)2PO-; an optionally substituted (hetero)aromatic system; W = a direct bond; oxygen; sulphur; optionally substituted nitrogen; A = -O-; -C(=O)-; -O-C(=O)-; -C(=O)-O-; -S-; -S(=O)-; -O-S(=0)--S(=O)-O-; -S(=O)2-; -O-S(=O)2-; -S(=O)2-O-; -NR -; -O-NR -; -NR -C(=O)-; -C(=O)-NR -; -NR -C(=O)-NR -; -NR -S(=O)-; -S(=O)-NR -; -NR -S-(=O)-NR -; -NR -S(=O)2-; -S(=O)2-NR -; -NR -S(=O)2-NR -; -N=N-; -NR -NR -; -NR -NR -C(=O)-; -C(=O)-NR -NR -; -NR -NR -S(=O)-; -S(=O)-NR -NR -; -NR -NR -S(=O)2-; -S(=O)2-NR -NR -; -O-(alkylene)-O-; -C-(=O)-(alkylene)-O-; -O-C(=O)-(alkylene)-O-; -C(=O)-O-(alkylene)-O-; -S-(alkylene)-O-; -S(=0)2-(alkylene)-O-; -O-S-(=O)2-(alkylene)-O-; -S(=O)2-O-(alkylene)-O-; -NR -(alkylene)-O-; -O-NR -(alkylene)-O-; -NR -C(=O)-(alkylene)-O-; -C(=O)-NR -(alkylene)-O-; -NR -C(=O)-NR -(alkylene)-O-; -N=N-(alkylene)-O-; -NR -NR -(alkylene)-O-; -NR -NR -C(=O)-(alkylene)-O-; -C(=O)-NR -NR -(alkylene)-O-; optionally substituted alkylene, alkenylene or alkynylene, it being possible for these carbon chains to be interrupted by one of the following groups or to be bonded to R or to the phenyl ring by one of the following groups: O, S, NR , CO, CO-O, O-CO, SO, SO2, SO2-O, O-SO2, NR -CO, CO-NR , NR -CO-NR , N=N, NR -NR , NR -NR -CO, CO-NR -NR ; R , R = H, alkyl or alkoxy, their preparation, fungicides and pesticides containing them, and their use.

公开(公告)号：ZA923534B

公开(公告)日：1993-11-15

申请号：ZA923534

申请日：1992-05-15

Applicant: BASF AG

Inventor： GRAMMENOS WASSILIOS ,  KIRSTGEN REINHARD ,  OBERDORF KLAUS ,  SAUTER HUBERT ,  ROEHL FRANZ ,  OTTER RAINER ,  AMMERMANN EBERHARD ,  LORENZ GISELA ,  KARDORFF UWE ,  KUENAST CHRISTOPH

IPC: A01N35/10 ,  A01N43/54 ,  A01N43/56 ,  A01N43/78 ,  C07C59/64 ,  C07C69/145 ,  C07C69/618 ,  C07C69/65 ,  C07C69/73 ,  C07C69/732 ,  C07C69/734 ,  C07C69/738 ,  C07C69/76 ,  C07C69/767 ,  C07C69/92 ,  C07C69/94 ,  C07C251/48 ,  C07C251/52 ,  C07C251/54 ,  C07C323/62 ,  C07D207/337 ,  C07D209/18 ,  C07D209/30 ,  C07D213/64 ,  C07D231/12 ,  C07D231/18 ,  C07D235/26 ,  C07D235/28 ,  C07D239/26 ,  C07D239/34 ,  C07D239/38 ,  C07D239/46 ,  C07D239/52 ,  C07D239/56 ,  C07D239/60 ,  C07D239/88 ,  C07D239/90 ,  C07D261/08 ,  C07D261/10 ,  C07D261/12 ,  C07D261/20 ,  C07D263/16 ,  C07D263/38 ,  C07D263/40 ,  C07D263/46 ,  C07D263/56 ,  C07D263/58 ,  C07D271/10 ,  C07D271/113 ,  C07D275/02 ,  C07D277/20 ,  C07D277/30 ,  C07D277/32 ,  C07D277/34 ,  C07D277/36 ,  C07D277/64 ,  C07D277/74 ,  C07D285/08 ,  C07D285/12 ,  C07D285/125 ,  C07D307/54 ,  C07D317/30 ,  C07D333/24 ,  C07F9/40 ,  C07D ,  C07C ,  C07F ,  A01N

Abstract: alpha -Phenylacrylic acid derivatives I in which n = 0 to 4; y = 0 or 1; R = H; alkyl; alkenyl; alkynyl; optionally substituted cycloalkyl; vinyl or ethynyl if W represents a direct bond; R = CN; alkenyl; alkynyl; optionally substituted cycloalkyl; optionally substituted alkyl; R = H; NO2; CN; halogen; alkyl; alkoxy; haloalkyl; haloalkoxy; alkylthio; or, in the event that n represents 2, 3 or 4, two adjacent substituents R together are optionally substituted 1,3-butadiene-1,4-diyl; R = H; CHO; optionally substituted alkyl; optionally substituted alkenyl; optionally substituted alkynyl; an optionally substituted saturated or unsaturated cyclic radical; (phenyl)3P-; (phenyl)2PO-; (alkoxy)2PO-; an optionally substituted (hetero)aromatic system; W = a direct bond; oxygen; sulphur; optionally substituted nitrogen; A = -O-; -C(=O)-; -O-C(=O)-; -C(=O)-O-; -S-; -S(=O)-; -O-S(=0)--S(=O)-O-; -S(=O)2-; -O-S(=O)2-; -S(=O)2-O-; -NR -; -O-NR -; -NR -C(=O)-; -C(=O)-NR -; -NR -C(=O)-NR -; -NR -S(=O)-; -S(=O)-NR -; -NR -S-(=O)-NR -; -NR -S(=O)2-; -S(=O)2-NR -; -NR -S(=O)2-NR -; -N=N-; -NR -NR -; -NR -NR -C(=O)-; -C(=O)-NR -NR -; -NR -NR -S(=O)-; -S(=O)-NR -NR -; -NR -NR -S(=O)2-; -S(=O)2-NR -NR -; -O-(alkylene)-O-; -C-(=O)-(alkylene)-O-; -O-C(=O)-(alkylene)-O-; -C(=O)-O-(alkylene)-O-; -S-(alkylene)-O-; -S(=0)2-(alkylene)-O-; -O-S-(=O)2-(alkylene)-O-; -S(=O)2-O-(alkylene)-O-; -NR -(alkylene)-O-; -O-NR -(alkylene)-O-; -NR -C(=O)-(alkylene)-O-; -C(=O)-NR -(alkylene)-O-; -NR -C(=O)-NR -(alkylene)-O-; -N=N-(alkylene)-O-; -NR -NR -(alkylene)-O-; -NR -NR -C(=O)-(alkylene)-O-; -C(=O)-NR -NR -(alkylene)-O-; optionally substituted alkylene, alkenylene or alkynylene, it being possible for these carbon chains to be interrupted by one of the following groups or to be bonded to R or to the phenyl ring by one of the following groups: O, S, NR , CO, CO-O, O-CO, SO, SO2, SO2-O, O-SO2, NR -CO, CO-NR , NR -CO-NR , N=N, NR -NR , NR -NR -CO, CO-NR -NR ; R , R = H, alkyl or alkoxy, their preparation, fungicides and pesticides containing them, and their use.