公开(公告)号：NO20005396A

公开(公告)日：2000-10-26

申请号：NO20005396

申请日：2000-10-26

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  WOHLLEBEN WOLFGANG ,  FISCHER PETER ,  LUTZ-WAHL SABINE ,  SCHMIDT-DANNERT CLAUDIA ,  SCHMID ROLF ,  SCHERR OLIVER

IPC: C07C403/16 ,  C12P1/06 ,  C12P7/02 ,  C12P7/26 ,  C12R1/465

CPC classification number: C12P7/26 ,  C12P7/02

公开(公告)号：CA2461139C

公开(公告)日：2013-08-27

申请号：CA2461139

申请日：2002-09-19

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  MATUSCHEK MARKUS ,  SCHMID ROLF ,  BUTA CHRISTIANE ,  KAUFFMANN ISABELLE ,  LAEMMLE KATRIN ,  ZIPPER HUBERT

IPC: C12N15/63 ,  G01N33/50 ,  B01J20/281 ,  C12N15/09 ,  C12N15/10 ,  C12N15/66 ,  C12Q1/68 ,  G01N21/78 ,  G01N30/26 ,  G01N30/88 ,  G01N33/24

Abstract: The invention relates to a method for producing a normalized gene library from nucleic acid extracts of soil samples and to the genetic structures and vectors used therein. The invention further relates to the use of the normalized gene library for screening genes that encode novel biocatalysts from soil samples.

公开(公告)号：CA2380186C

公开(公告)日：2012-03-13

申请号：CA2380186

申请日：2000-07-27

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN ,  LUTZ-WAHL SABINE ,  APPEL DANIEL

IPC: C12N15/09 ,  C12N15/53 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/70 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19

Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.

公开(公告)号：AU2002219040B2

公开(公告)日：2006-06-22

申请号：AU2002219040

申请日：2001-10-16

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  MERKL RAINER ,  SCHMID ROLF ,  BLASCO FRANCESCA

IPC: C12N9/02 ,  C12N15/09 ,  C12M1/40 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/53 ,  C12P1/04 ,  C12P7/00 ,  C12R1/01

Abstract: The invention relates to novel cytochrome P450 monooxygenases from thermophilic bacteria, in particular the genus Thermus sp., to nucleotide sequences encoding them, to the recombinant production of these monooxygenases and to their use for the microbiological oxidation of organic compounds.

公开(公告)号：DE10321082A1

公开(公告)日：2004-11-25

申请号：DE10321082

申请日：2003-05-09

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  HABICHER TILO ,  SCHMID ROLF ,  MAURER STEFFEN CHRISTIAN ,  URLACHER VLADA BENIAMINOVNA ,  SCHULZE HOLGER ,  HUBER NORBERT ,  BACHMANN TILL T

IPC: C12N9/02 ,  C12P7/02

Abstract: A process for preparing a hydroxylation catalyst by i) embedding a cystochrome P450 monooxygenase in a sol-gel matrix, ii) embedding an enzymatic NADPH-regenerating system in a sol-gel matrix, and combining the two components i) and ii) unless they were already mixed together before the embedding.

公开(公告)号：CA2425927A1

公开(公告)日：2003-04-14

申请号：CA2425927

申请日：2001-10-16

Applicant: BASF AG

Inventor： MERKL RAINER ,  BLASCO FRANCESCA ,  SCHMID ROLF ,  HAUER BERNHARD

IPC: C12N15/09 ,  C12M1/40 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/02 ,  C12N15/53 ,  C12P1/04 ,  C12P7/00 ,  C12R1/01 ,  C12Q1/68

Abstract: The invention relates to novel cytochrome P450 monooxygenases consisting of thermophilic bacteria, especially the species Thermus sp., nucleotide sequences coding for the same, the recombinant production of said monooxygenases and the use thereof for the microbiological oxidation of organic compounds.

公开(公告)号：DE10146572A1

公开(公告)日：2003-04-10

申请号：DE10146572

申请日：2001-09-21

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  MATUSCHEK MARKUS ,  SCHMID ROLF ,  BUTA CHRISTIANE ,  KAUFFMANN ISABELLE ,  LAEMMLE KATRIN ,  ZIPPER HUBERT

IPC: G01N33/50 ,  B01J20/281 ,  C12N15/09 ,  C12Q1/68 ,  G01N21/78 ,  G01N30/26 ,  G01N30/88 ,  G01N33/24 ,  C12N15/10 ,  C12N15/63

Abstract: The invention relates to a method for producing a normalized gene library from nucleic acid extracts of soil samples and to the genetic structures and vectors used therein. The invention further relates to the use of the normalized gene library for screening genes that encode novel biocatalysts from soil samples.

公开(公告)号：DE19955605A1

公开(公告)日：2001-05-23

申请号：DE19955605

申请日：1999-11-18

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QUING-SHAN

IPC: C12N9/02 ,  C12N15/53 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P17/10 ,  C12P17/16

Abstract: Cytochrome P450 monooxygenase (I) that can oxidize at least one of the following types of substrates(A): (i) optionally substituted mono- or poly-cyclic aromatic heterocyclics containing nitrogen, sulfur or oxygen; (ii) optionally substituted mono- or poly-cyclic aromatics; (iii) linear or branched alkanes or alkenes, or (iv) optionally substituted cycloalkanes or cycloalkenes, is new.

公开(公告)号：AU6830700A

公开(公告)日：2001-02-13

申请号：AU6830700

申请日：2000-07-27

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN

IPC: C12N15/09 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/53 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19 ,  C12N15/70

Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.

公开(公告)号：NO20005396D0

公开(公告)日：2000-10-26

申请号：NO20005396

申请日：2000-10-26

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  WOHLLEBEN WOLFGANG ,  FISCHER PETER ,  LUTZ-WAHL SABINE ,  SCHMIDT-DANNERT CLAUDIA ,  SCHMID ROLF ,  SCHERR OLIVER

IPC: C07C403/16 ,  C12P1/06 ,  C12P7/02 ,  C12P7/26 ,  C12R1/465 ,  C12P

Abstract: The invention relates to a process for the oxidation of substituted trimethylcyclohexenyl compounds in the presence of microorganisms of the order Actinomycetales and to the use of microorganisms in oxidation reactions.