公开(公告)号：DE102005057681A1

公开(公告)日：2007-06-06

申请号：DE102005057681

申请日：2005-12-01

Applicant: BASF AG

Inventor： SCHMIDT THOMAS ,  GEBHARDT JOACHIM ,  LOEHR SANDRA ,  KEIL MICHAEL ,  WEVERS JAN HENDRIK ,  RACK MICHAEL ,  MAYER GUIDO

IPC: C07C201/12 ,  B01J31/06 ,  C07C205/58

Abstract: Preparation of fluorinated m-nitro-benzoic acid chloride compound (I) comprises reacting a fluorinated m-nitro-benzoic acid compound (II) with a chlorinating agent, in the presence of a catalytic amount of phosphine derivative (III). Preparation of fluorinated m-nitro-benzoic acid chloride compound of formula (I) comprises reacting a fluorinated m-nitro-benzoic acid compound of formula (II) with a chlorinating agent, in the presence of a catalytic amount of phosphine derivative (III) of formula (Ra-P(=X n)(Rb)-Rc). R 1>-R 4>H, halo, CN, NO 2, 1-6C alkyl, 1-6C haloalkyl, 1-6C alkoxy or 1-6C haloalkoxy (where at least one of the residue is F); Ra-Rc : 1-6C alkyl or phenyl (optionally substituted by 1-4C alkyl); X : O or two single bonded Cl atom; and n : 0 or 1. An independent claim is included for the preparation of a sulfonamide compound of formula (V) comprising reacting (I) with an aminosulfone compound of formula (NH 2-SO 2NR 5>R 6>) (VI). R 5>, R 6>H, 1-6C alkyl (preferred), 3-6C alkenyl, 3-6C alkynyl, 3-7C cycloalkyl, 3-7C cycloalkenyl, 1-6C alkoxy, phenyl or benzyl. [Image] [Image].

公开(公告)号：DE60034254D1

公开(公告)日：2007-05-16

申请号：DE60034254

申请日：2000-12-23

Applicant: BASF AG

Inventor： PFRENGLE ANDREAS ,  SCHEFFER ROBERT J ,  SCHEIBLICH STEFAN DR ,  WEVERS JAN HENDRIK ,  VOGELBACHER UWE JOSEF ,  DOEHNER ROBERT F

IPC: C07C67/343 ,  C07C69/88

公开(公告)号：DK1572613T3

公开(公告)日：2006-12-18

申请号：DK03785691

申请日：2003-12-01

Applicant: BASF AG

Inventor： MAYWALD VOLKER ,  HOFFMANN NICO ,  KEIL MICHAEL ,  VOGELBACHER UWE JOSEF ,  WEVERS JAN HENDRIK

IPC: C07C45/46 ,  C07C45/81 ,  C07C49/84 ,  C07C51/363 ,  C07C51/60

Abstract: A process for preparing benzophenones of the formula I, where X may be chlorine, hydroxyl, methoxy or C 1 -C 6 -alkylcarbonyloxy, and Y may be chlorine or bromine, by reacting an acid chloride of the formula II where X and Y are as defined above with 3,4,5-trimethoxytoluene, which comprises carrying out the reaction in the presence of a) an aromatic hydrocarbon as a diluent and b) from 0.01 to 0.2 mol % of an iron catalyst, based on the acid chloride, c) at a temperature between 60° C. and the boiling point of the particular diluent.

公开(公告)号：AU2006251185A1

公开(公告)日：2006-11-30

申请号：AU2006251185

申请日：2006-05-18

Applicant: BASF AG

Inventor： KEIL MICHAEL ,  WEVERS JAN HENDRIK ,  SCHMIDT THOMAS ,  GEBHARDT JOACHIM ,  ZECH HELMUT ,  HABERLE RUDOLF ,  LOHR SANDRA

IPC: C07D239/54

Abstract: The present invention relates to a process for preparing 1-alkyl-3-phenyluracils of the formula I where the variables R1 to R7 are as defined in the description by reacting 3-phenyluracils of the formula II and alkylating agents of the formula III R1-L1  III, with one another, wherein during the entire reaction the pH is kept in a range from 1 to 6 by adding base a little at a time.

公开(公告)号：DE69829613T2

公开(公告)日：2005-09-15

申请号：DE69829613

申请日：1998-08-17

Applicant: BASF AG

Inventor： KNELL MARCUS ,  BRINK MONIKA ,  WEVERS JAN HENDRIK ,  HEINZ WILLI

IPC: C07D213/79 ,  C07D20060101 ,  C07D213/00 ,  C07D213/02 ,  C07D213/04 ,  C07D213/60 ,  C07D213/78 ,  C07D213/80 ,  C07D213/803 ,  C07D213/81 ,  C07D213/82 ,  C07D401/12 ,  C07D401/14 ,  C07D403/00

Abstract: The invention relates to a process for the preparation of heteroarylcarboxylic amides and esters of formula I in which A through A , R , Hal and X one or two of the groups A , A , A , A and A represent a nitrogen atom and the other groups each independently represent CR , Hal represents a halogen atom, X represents oxygen or NR , R1 represents an optionally substituted alkyl, aryl, heteroaryl or cycloalkyl group, R represents a hydrogen atom or an alkyl group, or R and R together with the interjacent ring form a heterocyclic group, and R each independently represent a hydrogen atom or an alkyl group, which comprises: heating a mixture consisting essentially of heteroaryltrichloromethane compound of formula II, in which A through A and Hal are as hereinbefore defined, and 1.0 to 1.5 equivalents of concentrated sulfuric acid, and reacting the resulting intermediate product with an alcohol or amine of formula III HXR optionally in the presence of a diluent and/or a base.

公开(公告)号：DK0749947T4

公开(公告)日：2002-06-17

申请号：DK96303932

申请日：1996-05-31

Applicant: BASF AG

Inventor： WEVERS JAN HENDRIK ,  SCHEFFER ROBERT JAN HENDRIK

IPC: C07C29/70 ,  C07C31/30

Abstract: There is provided a safe, efficient process for the production of sodium C4-C8alkoxide which utilizes a less than stoichiometric quantity of a C4-C8alcohol and the option of a continuous recycle of the unreacted sodium metal.

公开(公告)号：BRPI0316844B1

公开(公告)日：2016-03-08

申请号：BR0316844

申请日：2003-12-01

Applicant: BASF AG

Inventor： WEVERS JAN HENDRIK ,  KEIL MICHAEL ,  HOFFMANN NICO ,  VOGELBACHER UWE JOSEF ,  MAYWALD VOLKER

IPC: C07C45/81 ,  C07C45/46 ,  C07C49/84 ,  C07C51/363 ,  C07C51/60

Abstract: "processo para preparar benzofenonas". um processo para preparar benzofenonas de fórmula i, em que x pode ser cloro, hidroxila, metoxi ou c~ 1~-c~ 6~-alquilcarbonilóxi, e y pode ser cloro ou bromo, reagindo um cloreto ácido de fórmula ii em que x e y são como definidos acima com 3,4,5-trimetoxitolueno, que compreende efetuar a reação na presença de a) um hidrocarboneto aromático como um diluente e b) de 0,0 1 a 0,2 % molar de um catalisador contendo ferro, com base no cloreto ácido, c) em temperatura entre 60 c e o ponto de ebulição do diluente usado.

公开(公告)号：AU2006251185B2

公开(公告)日：2011-04-07

申请号：AU2006251185

申请日：2006-05-18

Applicant: BASF AG

Inventor： KEIL MICHAEL ,  WEVERS JAN HENDRIK ,  SCHMIDT THOMAS ,  GEBHARDT JOACHIM ,  ZECH HELMUT ,  HABERLE RUDOLF ,  LOHR SANDRA

IPC: C07D239/54

Abstract: The present invention relates to a process for preparing 1-alkyl-3-phenyluracils of the formula I where the variables R1 to R7 are as defined in the description by reacting 3-phenyluracils of the formula II and alkylating agents of the formula III R1-L1  III, with one another, wherein during the entire reaction the pH is kept in a range from 1 to 6 by adding base a little at a time.

公开(公告)号：CA2508714C

公开(公告)日：2011-04-05

申请号：CA2508714

申请日：2003-12-01

Applicant: BASF AG

Inventor： MAYWALD VOLKER ,  HOFFMANN NICO ,  KEIL MICHAEL ,  VOGELBACHER UWE JOSEF ,  WEVERS JAN HENDRIK

IPC: C07C45/46 ,  C07C45/81 ,  C07C49/84 ,  C07C51/363 ,  C07C51/60

Abstract: Disclosed is a method for producing benzophenones of formula I, wherein X can represent chlorine, hydroxy, methoxy, or C1-C6 alkylcarbonyloxy while Y represents chlorine or bromine, by reacting an acid chloride of formula II, wherein X and Y have the meaning mentioned above, with 3,4,5-trimethoxytoluene. The inventive method is characterized by the fact that the reaction is carried out in the presence of a) an aromatic hydrocarbon as a thinner, and b) 0.01 to 0.2 mole percent of an iron catalyst, the percentage being in relation to the acid chloride, c) at a temperature ranging between 60oC and the boiling point of the respective thinner.

公开(公告)号：AU2003294750B2

公开(公告)日：2010-04-01

申请号：AU2003294750

申请日：2003-12-01

Applicant: BASF AG

Inventor： KEIL MICHAEL ,  WEVERS JAN HENDRIK ,  HOFFMANN NICO ,  VOGELBACHER UWE JOSEF ,  MAYWALD VOLKER

IPC: C07C45/46 ,  C07C45/81 ,  C07C51/363 ,  C07C51/60

Abstract: A process for preparing benzophenones of the formula I, where X may be chlorine, hydroxyl, methoxy or C 1 -C 6 -alkylcarbonyloxy, and Y may be chlorine or bromine, by reacting an acid chloride of the formula II where X and Y are as defined above with 3,4,5-trimethoxytoluene, which comprises carrying out the reaction in the presence of a) an aromatic hydrocarbon as a diluent and b) from 0.01 to 0.2 mol % of an iron catalyst, based on the acid chloride, c) at a temperature between 60° C. and the boiling point of the particular diluent.